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Product Details
MA5-17181
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:200-1:1,000 | - |
Flow Cytometry (Flow) |
1:200 - 1:400 | - |
ELISA (ELISA) |
1:10,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1G4 |
Immunogen |
Purified recombinant fragment of human SRY (amino acids:1-204) expressed in E. Coli. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS |
Contains |
0.05% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2538652 |
Product Specific Information
MA5-17181 targets SRY in FACS, IHC, pep-ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17181 immunogen is purified recombinant fragment of human SRY (amino acids:1-204) expressed in E. Coli.
MA5-17181 detects SRY which has a predicted molecular weight of approximately 23.9kDa.
Target Information
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: essential protein for sex determination in human males; sex determining region Y protein; sex-determining region on Y; Sex-determining region Y protein; Testis-determining factor; testis-determining factor on Y
Gene Aliases: SRXX1; SRXY1; SRY; TDF; TDY
UniProt ID: (Human) Q05066
Entrez Gene ID: (Human) 6736
Molecular Function:
HMG box transcription factor
Performance Guarantee
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