This antibody is predicted to react with bovine, canine, human and rat based on sequence homology.
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE domain, and an N-terminal regulatory domain. Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: adipocyte; adiponectin; FP17469; HGNC:11433; Neuron-specific antigen HPC-1; syntaxin 1 a; syntaxin 1B1; syntaxin 1B2; syntaxin a/b; Syntaxin-1A; Syntaxin-1B
Gene Aliases: HPC-1; Stx1a; Stx1b; Stx1b1; Stx1b2; Stx1bl; Syn1b