|Tested species reactivity||Human, Mouse, Zebrafish|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human Syntenin 1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
PA5-28813 targets Syntenin 1 in IF and WB applications and shows reactivity with Human samples.
The PA5-28813 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 45 of Human Syntenin 1.
The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.
MDA-9; melanoma differentiation associated protein-9; melanoma differentiation-associated protein 9; pro-TGF-alpha cytoplasmic domain-interacting protein 18; scaffold protein Pbp1; ST1; SYCL; syndecan binding protein (syntenin); syndecan interacting protein; syndecan-binding protein 1; syntenin; syntenin-1; TACIP18
MDA-9; MDA9; SDCBP; ST1; SYCL; syntenin-1; TACIP18