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      TGFBR2 Polyclonal Antibody

      See 7 other TGFBR2 antibodies ›
      TGFBR2 Polyclonal Antibody for Western Blot, IF, ICC and IHC (P)

      Catalog#: PA5-35076 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      PA5-35076 400 µL
      349.00
      Please enter a quantity in the range of 1 to 199.
      Suggested Secondary Antibodies

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      Product Details

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human, Mouse
      Host / Isotype Rabbit / IgG
      Class Polyclonal
      Type Antibody
      Immunogen KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human TGFBR2
      Conjugate Unconjugated
      Form Liquid
      Concentration Lot-Specific
      Purification Antigen affinity chromatography
      Storage buffer PBS
      Contains 0.09% sodium azide
      Storage Conditions -20° C, Avoid Freeze/Thaw Cycles
      Tested Applications Dilution *
      Immunocytochemistry (ICC) 1:10-1:50
      Immunofluorescence (IF) 1:10-1:50
      Immunohistochemistry (Paraffin) (IHC (P)) 1:10-1:50
      Western Blot (WB) 1:1000

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Background/Target Information

      This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      Bioinformatics

      Protein Aliases:

      tbetaR-II; TGF-beta receptor II; TGF-beta receptor type II; TGF-beta receptor type IIB; TGF-beta receptor type-2; TGF-beta type II receptor; TGFBR2; TGFR-2; transforming growth factor beta receptor II; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor II (70/80kDa); transforming growth factor, beta receptor II alpha; transforming growth factor, beta receptor II beta; transforming growth factor, beta receptor II delta; transforming growth factor, beta receptor II epsilon; transforming growth factor, beta receptor II gamma; Transforming growth factor-beta receptor type II

      Gene Aliases:

      1110020H15Rik; AAT3; AU042018; DNIIR; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; RIIDN; TAAD2; TbetaR-II; TbetaRII; TBR-II; TGFbeta-RII; TGFBR2; TGFR-2

      UniProt ID:

      (Human) P37173, (Mouse) Q62312

      Entrez Gene ID:

      (Human) 7048, (Mouse) 21813

      Molecular Function:

      TGF-beta receptor cytokine receptor kinase protein kinase protein kinase receptor receptor serine/threonine protein kinase receptor transferase

      Function(s) Process(es)

      Documents

      Material safety data sheets (MSDS)

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