MA5-17187 targets TGFBR3 in WB applications and shows reactivity with Human and Mouse samples.
The MA5-17187 immunogen is purified recombinant fragment of human TGFBR3 (amino acids: 147-328 ) expressed in E. Coli.
MA5-17187 detects TGFBR3 which has a predicted molecular weight of approximately 93.4kDa.
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Betaglycan; betaglycan proteoglycan; TGF-beta receptor type 3; TGF-beta receptor type III; TGFR-3; Transforming growth factor beta receptor III; Transforming growth factor beta receptor type 3
Gene Aliases: 1110036H20Rik; AU015626; AW215636; betaglycan; BGCAN; TBRIII; TGFBR3