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Product Details
MA5-15413
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
ELISA (ELISA) |
1:10,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1B5G3;3F11H6 |
Immunogen |
Purified recombinant fragment of TNK1 (aa451-560) expressed in E. Coli. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
Conc. Not Determined |
Storage buffer |
ascites |
Contains |
0.03% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_10982180 |
Product Specific Information
MA5-15413 targets TNK1 in WB applications and shows reactivity with Human samples.
The MA5-15413 immunogen is purified recombinant fragment of TNK1 (aa451-560) expressed in E. Coli.
.
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD38 negative kinase 1; MGC46193; Non-receptor tyrosine-protein kinase TNK1; TNK1; tyrosine kinase, non-receptor 1; tyrosine kinase, non-receptor, 1
Gene Aliases: TNK1
UniProt ID: (Human) Q13470
Entrez Gene ID: (Human) 8711
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
cell differentiation
negative regulation of cell growth
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
negative regulation of Ras protein signal transduction
protein autophosphorylation
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