The protein encoded by TRMT2A is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of TRMT2A varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for TRMT2A.
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Protein Aliases: HpaII tiny fragments locus 9c protein; TRM2 tRNA methyltransferase 2 homolog A; tRNA (uracil-5-)-methyltransferase homolog A
Gene Aliases: HTF9C; TRMT2A
UniProt ID: (Human) Q8IZ69
Entrez Gene ID: (Human) 27037
Molecular Function: RNA methyltransferase