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This gene is a member of the transient receptor family and the TrpV subfamily. The calcium-selective channel encoded by this gene has 6 transmembrane-spanning domains, multiple potential phosphorylation sites, an N-linked glycosylation site, and 5 ANK repeats. This protein forms homotetramers or heterotetramers and is activated by a low internal calcium level.
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Protein Aliases: Calciu; Calcium transport protein 2; Calcium transporter 2; CaT2; ECaC; ECaC1; Epithelial calcium channel 1; Osm-9-like TRP channel 3; OTRPC3; Transient receptor potential cation channel subfamily V member 5; transient receptor potential cation channel, subfamily V, member 5; TrpV5
Gene Aliases: CAT2; D630033B11; Ecac; ECAC1; OTRPC3; TRPV5
UniProt ID: (Human) Q9NQA5, (Rat) Q9JIP0, (Mouse) P69744
Entrez Gene ID: (Human) 56302, (Rat) 116469, (Mouse) 194352
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