MA5-12293 targets Tyrosinase Related Protein 75 in IHC (F) and WB applications and shows reactivity with Human samples.
The MA5-12293 immunogen is sK-MEL-23 Melanoma cell line.
This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.
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Protein Aliases: 5,6-dihydroxyindole-2-carboxylic acid oxidase; Catalase B; DHICA oxidase; Glycoprotein 75; Melanoma antigen gp75; MGC120175; MGC149362; RP11-3L8.1; TRP; TRY1; TRY4; TRYP1; Tyrosinase-related protein 1
Gene Aliases: b-PROTEIN; CAS2; CATB; GP75; OCA3; TRP; TRP1; TYRP; TYRP1; TYRRP
UniProt ID: (Human) P17643
Entrez Gene ID: (Human) 7306