MA5-12293 targets Tyrosinase Related Protein 75 in IHC (F) and WB applications and shows reactivity with Human samples.
The MA5-12293 immunogen is sK-MEL-23 Melanoma cell line.
Tyrosinase related Protein 75 (TRP75/gp75) is a pigmentation associated proteins expressed by melanoma cells and normal melanocytes. This antigen appears to be expressed during the stage III and IV of melanosomes.
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Protein Aliases: 5; 5,6-dihydroxyindole-2-carboxylic acid oxidase; 6-dihydroxyindole-2-carboxylic acid oxidase; Catalase B; DHICA oxidase; Glycoprotein 75; Melanoma antigen gp75; TRP; Tyrosinase-related protein 1
Gene Aliases: b-PROTEIN; CAS2; CATB; GP75; OCA3; TRP; TRP1; TYRP; TYRP1; TYRRP
UniProt ID: (Human) P17643
Entrez Gene ID: (Human) 7306