Product References
Butyrate prevents visceral adipose tissue inflammation and metabolic alterations in a Friedreich's ataxia mouse model.
iScience
Turchi R,Sciarretta F,Ceci V,Tiberi M,Audano M,Pedretti S,Panebianco C,Nesci V,Pazienza V,Ferri A,Carotti S,Chiurchiù V,Mitro N,Lettieri-Barbato D,Aquilano K
MA5-11690 was used in Western Blot to understand its role in Friedreich's ataxia-related metabolic complications.
Fri Oct 20 00:00:00 UTC 2023
Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin-deficient mice.
EMBO molecular medicine
Farini A,Tripodi L,Villa C,Strati F,Facoetti A,Baselli G,Troisi J,Landolfi A,Lonati C,Molinaro D,Wintzinger M,Gatti S,Cassani B,Caprioli F,Facciotti F,Quattrocelli M,Torrente Y
MA5-11690 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to identify a potential role for the gut microbiota in the pathogenesis of DMD.
Wed Mar 08 00:00:00 UTC 2023
Pathway choice in the alternative telomere lengthening in neoplasia is dictated by replication fork processing mediated by EXD2's nuclease activity.
Nature communications
Broderick R,Cherdyntseva V,Nieminuszczy J,Dragona E,Kyriakaki M,Evmorfopoulou T,Gagos S,Niedzwiedz W
MA5-11690 was used in Western Blotting to demonstrate that EXD2 loss leads to telomere shortening, elevated telomeric sister chromatid exchanges, C-circle formation as well as BIR-mediated telomeric replication.
Thu Apr 27 00:00:00 UTC 2023
The RabGAPs EPI64A and EPI64B regulate the apical structure of epithelial cells †.
Molecular biology of the cell
Miller MR,McDermitt DJ,Sauvanet C,Lombardo AT,Zaman R,Bretscher A
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Immunocytochemistry
Sat Jan 01 00:00:00 UTC 2022
The Downregulation of Both Giant HERCs, HERC1 and HERC2, Is an Unambiguous Feature of Chronic Myeloid Leukemia, and HERC1 Levels Are Associated with Leukemic Cell Differentiation.
Journal of clinical medicine
Ali MS,Magnati S,Panuzzo C,Cilloni D,Saglio G,Pergolizzi B,Bracco E
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Western Blot
Mon Jan 10 00:00:00 UTC 2022
Chemical, Molecular, and Single-nucleus Analysis Reveal Chondroitin Sulfate Proteoglycan Aberrancy in Fibrolamellar Carcinoma.
Cancer research communications
Francisco AB,Li J,Farghli AR,Kanke M,Shui B,Munn PR,Grenier JK,Soloway PD,Wang Z,Reid LM,Liu J,Sethupathy P
MA5-11690 was used in Western Blotting to reveal a pathologic aberrancy in chondroitin (but not heparan) sulfate proteoglycans in FLC and highlight a potential role for activated stellate cells.
Fri Jul 01 00:00:00 UTC 2022
Chemical, Molecular, and Single-nucleus Analysis Reveal Chondroitin Sulfate Proteoglycan Aberrancy in Fibrolamellar Carcinoma.
Cancer research communications
Francisco AB,Li J,Farghli AR,Kanke M,Shui B,Munn PR,Grenier JK,Soloway PD,Wang Z,Reid LM,Liu J,Sethupathy P
MA5-11690 was used in Western Blotting to reveal a pathologic aberrancy in chondroitin (but not heparan) sulfate proteoglycans in FLC and highlight a potential role for activated stellate cells.
Fri Jul 01 00:00:00 UTC 2022
Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization.
Cell reports
Romano LEL,Aw WY,Hixson KM,Novoselova TV,Havener TM,Howell S,Taylor-Blake B,Hall CL,Xing L,Beri J,Nethisinghe S,Perna L,Hatimy A,Altadonna GC,Graves LM,Herring LE,Hickey AJ,Thalassinos K,Chapple JP,Wolter JM
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Immunocytochemistry
Tue Nov 01 00:00:00 UTC 2022
Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization.
Cell reports
Romano LEL,Aw WY,Hixson KM,Novoselova TV,Havener TM,Howell S,Taylor-Blake B,Hall CL,Xing L,Beri J,Nethisinghe S,Perna L,Hatimy A,Altadonna GC,Graves LM,Herring LE,Hickey AJ,Thalassinos K,Chapple JP,Wolter JM
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Immunocytochemistry
Tue Nov 01 00:00:00 UTC 2022
Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization.
Cell reports
Romano LEL,Aw WY,Hixson KM,Novoselova TV,Havener TM,Howell S,Taylor-Blake B,Hall CL,Xing L,Beri J,Nethisinghe S,Perna L,Hatimy A,Altadonna GC,Graves LM,Herring LE,Hickey AJ,Thalassinos K,Chapple JP,Wolter JM
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Immunocytochemistry
Tue Nov 01 00:00:00 UTC 2022
Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization.
Cell reports
Romano LEL,Aw WY,Hixson KM,Novoselova TV,Havener TM,Howell S,Taylor-Blake B,Hall CL,Xing L,Beri J,Nethisinghe S,Perna L,Hatimy A,Altadonna GC,Graves LM,Herring LE,Hickey AJ,Thalassinos K,Chapple JP,Wolter JM
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Immunocytochemistry
Tue Nov 01 00:00:00 UTC 2022
Rora Regulates Neutrophil Migration and Activation in Zebrafish.
Frontiers in immunology
Hsu AY,Wang T,Syahirah R,Liu S,Li K,Zhang W,Wang J,Cao Z,Tian S,Matosevic S,Staiger CJ,Wan J,Deng Q
MA5-11690 was used in Western Blotting to reveal previously unknown functions of miR-99 and RORα in regulating neutrophil migration and anti-microbial defense.
Mon May 02 00:00:00 UTC 2022
Control of backbone chemistry and chirality boost oligonucleotide splice switching activity.
Nucleic acids research
Kandasamy P,McClorey G,Shimizu M,Kothari N,Alam R,Iwamoto N,Kumarasamy J,Bommineni GR,Bezigian A,Chivatakarn O,Butler DCD,Byrne M,Chwalenia K,Davies KE,Desai J,Shelke JD,Durbin AF,Ellerington R,Edwards B,Godfrey J,Hoss A,Liu F,Longo K,Lu G,Marappan S,Oieni J,Paik IH,Estabrook EP,Shivalila C,Tischbein M,Kawamoto T,Rinaldi C,Rajão-Saraiva J,Tripathi S,Yang H,Yin Y,Zhao X,Zhou C,Zhang J,Apponi L,Wood MJA,Vargeese C
MA5-11690 was used in Simple Western - Size to conclude that chimeric stereopure oligonucleotides are a promising splice-switching modality with potential for the treatment of neuromuscular and other genetic diseases impacting difficult to reach tissues such as the skeletal muscle and heart.
Fri Jun 10 00:00:00 UTC 2022
Immunoproteasome Inhibition Ameliorates Aged Dystrophic Mouse Muscle Environment.
International journal of molecular sciences
Tripodi L,Molinaro D,Fortunato F,Mella C,Cassani B,Torrente Y,Farini A
MA5-11690 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to show that ONX-0914 is a promising molecule that may slow down muscle mass loss, with relatively low side effects, in dystrophic patients with moderate to advanced disease.
Thu Nov 24 00:00:00 UTC 2022
IL-9 Abrogates the Metastatic Potential of Breast Cancer by Controlling Extracellular Matrix Remodeling and Cellular Contractility.
Journal of immunology (Baltimore, Md. : 1950)
Das S,Surve V,Marathe S,Wad S,Karulkar A,Srinivasan S,Dwivedi A,Barthel SR,Purwar R
MA5-11690 was used in Flow cytometry/Cell sorting to support that IL-9 inhibits the metastatic potential of breast and cervical cancer cells by controlling extracellular matrix remodeling and cellular contractility.
Tue Jun 01 00:00:00 UTC 2021
Defective dystrophic thymus determines degenerative changes in skeletal muscle.
Nature communications
Farini A,Sitzia C,Villa C,Cassani B,Tripodi L,Legato M,Belicchi M,Bella P,Lonati C,Gatti S,Cerletti M,Torrente Y
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Western Blot
Thu Apr 08 00:00:00 UTC 2021
Defective dystrophic thymus determines degenerative changes in skeletal muscle.
Nature communications
Farini A,Sitzia C,Villa C,Cassani B,Tripodi L,Legato M,Belicchi M,Bella P,Lonati C,Gatti S,Cerletti M,Torrente Y
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Western Blot
Thu Apr 08 00:00:00 UTC 2021
Effect of Epigallocatechin-3-Gallate on EGFR Signaling and Migration in Non-Small Cell Lung Cancer.
International journal of molecular sciences
Minnelli C,Cianfruglia L,Laudadio E,Mobbili G,Galeazzi R,Armeni T
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Western Blot
Sun Oct 31 00:00:00 UTC 2021
Effect of Epigallocatechin-3-Gallate on EGFR Signaling and Migration in Non-Small Cell Lung Cancer.
International journal of molecular sciences
Minnelli C,Cianfruglia L,Laudadio E,Mobbili G,Galeazzi R,Armeni T
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Western Blot
Sun Oct 31 00:00:00 UTC 2021
Flavonoids and Omega3 Prevent Muscle and Cardiac Damage in Duchenne Muscular Dystrophy Animal Model.
Cells
Tripodi L,Molinaro D,Farini A,Cadiao G,Villa C,Torrente Y
MA5-11690 was used in Western Blot to propose FLAVOmega β as food supplement suitable for preventing muscle weakness, delaying inflammatory milieu, and sustaining physical health in patients affected from DMD.
Thu Oct 28 00:00:00 UTC 2021
The Giant HECT E3 Ubiquitin Ligase HERC1 Is Aberrantly Expressed in Myeloid Related Disorders and It Is a Novel BCR-ABL1 Binding Partner.
Cancers
Ali MS,Panuzzo C,Calabrese C,Maglione A,Piazza R,Cilloni D,Saglio G,Pergolizzi B,Bracco E
MA5-11690 was used in Western Blotting to determine that HERC1, a large HECT E3 Ubiquitin Ligase, may be involved in suppressing or promoting tumours.
Tue Jan 19 00:00:00 UTC 2021
Lysine in Combination With Estradiol Promote Dissemination of Estrogen Receptor Positive Breast Cancer via Upregulation of U2AF1 and RPN2 Proteins.
Frontiers in oncology
Vazquez Rodriguez G,Abrahamsson A,Turkina MV,Dabrosin C
MA5-11690 was used in Immunocytochemistry to sample extracellular essential amino acids in vivo by microdialysis in human breast cancer.
Fri Dec 18 00:00:00 UTC 2020
Lysine in Combination With Estradiol Promote Dissemination of Estrogen Receptor Positive Breast Cancer via Upregulation of U2AF1 and RPN2 Proteins.
Frontiers in oncology
Vazquez Rodriguez G,Abrahamsson A,Turkina MV,Dabrosin C
MA5-11690 was used in Immunocytochemistry to sample extracellular essential amino acids in vivo by microdialysis in human breast cancer.
Fri Dec 18 00:00:00 UTC 2020
Truncation of MYH8 tail in AML: a novel prognostic marker with increase cell migration and epithelial-mesenchymal transition utilizing RAF/MAPK pathway.
Carcinogenesis
Park H,Kim D,Kim D,Park J,Koh Y,Yoon SS
MA5-11690 was used in Immunocytochemistry-immunoflourescence to establish knock-in cell lines using CRISPR-Cas9 genome editing. Using the established mutant model, we assessed traits of cancer progress.
Fri Jul 10 00:00:00 UTC 2020
PTX3 Predicts Myocardial Damage and Fibrosis in Duchenne Muscular Dystrophy.
Frontiers in physiology
Farini A,Villa C,Di Silvestre D,Bella P,Tripodi L,Rossi R,Sitzia C,Gatti S,Mauri P,Torrente Y
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Western Blot
Mon Sep 28 00:00:00 UTC 2020
PTX3 Predicts Myocardial Damage and Fibrosis in Duchenne Muscular Dystrophy.
Frontiers in physiology
Farini A,Villa C,Di Silvestre D,Bella P,Tripodi L,Rossi R,Sitzia C,Gatti S,Mauri P,Torrente Y
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Western Blot
Mon Sep 28 00:00:00 UTC 2020
LHRH-Conjugated Drugs as Targeted Therapeutic Agents for the Specific Targeting and Localized Treatment of Triple Negative Breast Cancer.
Scientific reports
Obayemi JD,Salifu AA,Eluu SC,Uzonwanne VO,Jusu SM,Nwazojie CC,Onyekanne CE,Ojelabi O,Payne L,Moore CM,King JA,Soboyejo WO
MA5-11690 was used in Immunocytochemistry-immunofluorescence to show that overexpressed Luteinizing Hormone-Releasing Hormone (LHRH) receptors serve as binding sites on the breast cancer cells/tumor and the LHRH-conjugated drugs inhibited the growth of breast cells/tumor in in vitro and in vivo experiments.
Tue May 19 00:00:00 UTC 2020
LHRH-Conjugated Drugs as Targeted Therapeutic Agents for the Specific Targeting and Localized Treatment of Triple Negative Breast Cancer.
Scientific reports
Obayemi JD,Salifu AA,Eluu SC,Uzonwanne VO,Jusu SM,Nwazojie CC,Onyekanne CE,Ojelabi O,Payne L,Moore CM,King JA,Soboyejo WO
MA5-11690 was used in Immunocytochemistry-immunofluorescence to show that overexpressed Luteinizing Hormone-Releasing Hormone (LHRH) receptors serve as binding sites on the breast cancer cells/tumor and the LHRH-conjugated drugs inhibited the growth of breast cells/tumor in in vitro and in vivo experiments.
Tue May 19 00:00:00 UTC 2020
Transferrin-targeted porous silicon nanoparticles reduce glioblastoma cell migration across tight extracellular space.
Scientific reports
Sheykhzadeh S,Luo M,Peng B,White J,Abdalla Y,Tang T,Mäkilä E,Voelcker NH,Tong WY
MA5-11690 was used in Immunocytochemistry to develop transferrin-conjugated porous silicon nanoparticles (Tf@pSiNP) and studied their effect on inhibiting GBM migration by means of a microfluidic-based migration chip.
Tue Feb 11 00:00:00 UTC 2020
Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression.
Nature communications
Lim KH,Han Z,Jeon HY,Kach J,Jing E,Weyn-Vanhentenryck S,Downs M,Corrionero A,Oh R,Scharner J,Venkatesh A,Ji S,Liau G,Ticho B,Nash H,Aznarez I
MA5-11690 was used in Western Blotting to explore the effect of antisense oligonucleotide modulation on downstream gene expression.
Thu Jul 09 00:00:00 UTC 2020
Vinculin variant M94I identified in sudden unexplained nocturnal death syndrome decreases cardiac sodium current.
Scientific reports
Cheng J,Kyle JW,Wiedmeyer B,Lang D,Vaidyanathan R,Makielski JC
MA511690 was used in immunoprecipitation to examine the physical and functional interaction between vinculin and the cardiac sodium channel and their role in sudden unexplained nocturnal death syndrome
Mon Feb 20 00:00:00 UTC 2017
Vinculin variant M94I identified in sudden unexplained nocturnal death syndrome decreases cardiac sodium current.
Scientific reports
Cheng J,Kyle JW,Wiedmeyer B,Lang D,Vaidyanathan R,Makielski JC
MA511690 was used in immunoprecipitation to examine the physical and functional interaction between vinculin and the cardiac sodium channel and their role in sudden unexplained nocturnal death syndrome
Mon Feb 20 00:00:00 UTC 2017
Vinculin variant M94I identified in sudden unexplained nocturnal death syndrome decreases cardiac sodium current.
Scientific reports
Cheng J,Kyle JW,Wiedmeyer B,Lang D,Vaidyanathan R,Makielski JC
MA511690 was used in immunoprecipitation to examine the physical and functional interaction between vinculin and the cardiac sodium channel and their role in sudden unexplained nocturnal death syndrome
Mon Feb 20 00:00:00 UTC 2017
An East Asian Common Variant Vinculin P.Asp841His Was Associated With Sudden Unexplained Nocturnal Death Syndrome in the Chinese Han Population.
Journal of the American Heart Association
Cheng J,Kyle JW,Lang D,Wiedmeyer B,Guo J,Yin K,Huang L,Vaidyanathan R,Su T,Makielski JC
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Western Blot
Mon Apr 03 00:00:00 UTC 2017
An East Asian Common Variant Vinculin P.Asp841His Was Associated With Sudden Unexplained Nocturnal Death Syndrome in the Chinese Han Population.
Journal of the American Heart Association
Cheng J,Kyle JW,Lang D,Wiedmeyer B,Guo J,Yin K,Huang L,Vaidyanathan R,Su T,Makielski JC
Published figure using Vinculin monoclonal antibody (Product # MA5-11690) in Western Blot
Mon Apr 03 00:00:00 UTC 2017
EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression.
PLoS pathogens
Currier MG,Lee S,Stobart CC,Hotard AL,Villenave R,Meng J,Pretto CD,Shields MD,Nguyen MT,Todd SO,Chi MH,Hammonds J,Krumm SA,Spearman P,Plemper RK,Sakamoto K,Peebles RS,Power UF,Moore ML
MA5-11690 was used in western blot to characterize the interaction with the fusion protein of respiratory syncytial virus strain 2-20 and mediation of infection and mucin expression by EGFR
Sun May 01 00:00:00 UTC 2016
Focal adhesion plaque associated cytoskeletons are involved in the invasion and metastasis of human colorectal carcinoma.
Cancer investigation
Yang HJ,Chen JZ,Zhang WL,Ding YQ
MA5-11690 was used in immunohistochemistry to investigate the involvement of focal adhesion plaque associated cytoskeletons in the invasion and metastasis of colorectal carcinoma
Mon Feb 01 00:00:00 UTC 2010
Connective tissue growth factor expression and induction by transforming growth factor-beta is abrogated by simvastatin via a Rho signaling mechanism.
American journal of physiology. Lung cellular and molecular physiology
Watts KL,Spiteri MA
MA5-11690 was used in western blot to investigate the influence of simvastatin on connective tissue growth factor expression and its mechanism
Wed Dec 01 00:00:00 UTC 2004
Focal complex formation in adult cardiomyocytes is accompanied by the activation of beta3 integrin and c-Src.
Journal of molecular and cellular cardiology
Willey CD,Balasubramanian S,Rodríguez Rosas MC,Ross RS,Kuppuswamy D
MA5-11690 was used in immunocytochemistry to investigate the involvement of beta3 integrin and c-Src in focal adhesion complex formation in adult cardiomyocytes
Sun Jun 01 00:00:00 UTC 2003
