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Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fragment corresponding to a region within amino acids 241 and 504 of ZC3H12A (Uniprot ID#Q5D1E8) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1.64 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7, with 20% glycerol |
Contains |
0.025% ProClin 300 |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_11155824 |
Recommended positive controls: 293T, A431.
Predicted reactivity: Bovine (83%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
ZC3H12A is an MCP1 -induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endoribonuclease ZC3H12A; MCP-1 treatment-induced protein; MCP-induced protein 1; Monocyte chemotactic protein-induced protein 1; Reg1; Regnase-1; ribonuclease ZC3H12A; RP3-423B22.1; Zinc finger CCCH domain-containing protein 12A
Gene Aliases: dJ423B22.1; MCPIP; MCPIP1; ZC3H12A
UniProt ID: (Human) Q5D1E8
Entrez Gene ID: (Human) 80149
Molecular Function:
endoribonuclease
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