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Invitrogen
alpha-Amanitin Monoclonal Antibody (3B9)
Product Details
MA5-49614
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
3B9
Immunogen
Conjugate of alpha-AMA hapten and KLH
Conjugate
Form
Liquid
Concentration
3.9 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_3090280
Product Specific Information
Antibody tested in indirect ELISA
Target Information
Alpha-amanitin is a cyclic peptide toxin found in certain species of mushrooms, including the death cap mushroom (Amanita phalloides). It is known for its potent inhibitory effects on RNA polymerase II, a key enzyme involved in transcription of genes. This inhibition can lead to liver failure and death in humans if ingested. Alpha-amanitin is also used in research as a tool to study gene expression and transcriptional regulation. It has been shown to be effective in killing cancer cells, and research is ongoing to explore its potential as a therapeutic agent for cancer treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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