Product References
Muscle fibre transition and transcriptional changes of horse skeletal muscles during traditional Mongolian endurance training.
Equine veterinary journal
Bou T,Ding W,Ren X,Liu H,Gong W,Jia Z,Zhang X,Dugarjaviin M,Bai D
Mon Jan 01 00:00:00 EST 2024
Virulence factors and mechanisms of paediatric pneumonia caused by Enterococcus faecalis.
Gut pathogens
Tian Z,Khan AI,Rehman AU,Deng T,Ma C,Wang L
Mon Jan 09 00:00:00 EST 2023
Wnt3a-Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Gao L,Sun Y,Zhang X,Ma D,Xie A,Wang E,Cheng L,Liu S
Thu Jun 01 00:00:00 EDT 2023
An enzyme-instructed self-assembly system induces tumor acidosis via sequential-dual effect for cancer selective therapy.
Acta biomaterialia
Zhang H,Wang Z,Gao T,Wang Z,Ren C,Liu J
Sat Jul 01 00:00:00 EDT 2023
Effect of Sublethal Concentrations of Metal Nanomaterials on Cell Energy Metabolism.
Toxics
Liang C,Jiang Q,Liu Z,Yang J,Zhang J,Zhang S,Xin W
Thu May 11 00:00:00 EDT 2023
Therapeutic role of Artemether in the prevention of hepatic steatosis through miR-34a-5p/PPARα pathway.
Drug development research
Chen L,Yu S,Hong S,Lin X,Zhu X,Cao X,Li Y,Xiao H
Sat Apr 01 00:00:00 EDT 2023
Crizotinib Nanomicelles Synergize with Chemotherapy through Inducing Proteasomal Degradation of Mutp53 Proteins.
ACS applied materials & interfaces
Yi T,Qian J,Ye Y,Zhang H,Jin X,Wang M,Yang Z,Zhang W,Wen L,Zhang Y
Wed Jan 11 00:00:00 EST 2023
The Mechanosensitive Ion Channel PIEZO1 in Intestinal Epithelial Cells Mediates Inflammation through the NOD-Like Receptor 3 Pathway in Crohn's Disease.
Inflammatory bowel diseases
Liu Q,Wang D,Yang X,Ma F,Han W,Hu J,Mei Q
Thu Jan 05 00:00:00 EST 2023
Viral Hemorrhagic Septicemia Virus Activates Integrated Stress Response Pathway and Induces Stress Granules to Regulate Virus Replication.
Viruses
Ramnani B,Powell S,Shetty AG,Manivannan P,Hibbard BR,Leaman DW,Malathi K
Tue Feb 07 00:00:00 EST 2023
BCKDHA contributes to melanoma progression by promoting the expressions of lipogenic enzymes FASN and ACLY.
Experimental dermatology
Tian Y,Ma J,Wang M,Yi X,Guo S,Wang H,Zhang H,Wang H,Yang Y,Zhang B,Du J,Shi Q,Gao T,Li C,Guo W
Sun Oct 01 00:00:00 EDT 2023
The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition.
Oxidative medicine and cellular longevity
Gao R,Wu Y,Yang Q,Chen L,Chen J,Wang B,Liu Z,Jin J,Li J,Wu G
Wed Feb 15 00:00:00 EST 2023
Effects of Si-Miao-Yong-An decoction on myocardial I/R rats by regulating gut microbiota to inhibit LPS-induced TLR4/NF-κB signaling pathway.
BMC complementary medicine and therapies
Cui Y,Zhang F,Xu W,Li Z,Zou J,Gao P,Hu J
Fri Jun 02 00:00:00 EDT 2023
PRSS2 regulates EMT and metastasis via MMP-9 in gastric cancer.
Acta histochemica
Wang F,Yi J,Chen Y,Bai X,Lu C,Feng S,Zhou X
Tue Aug 01 00:00:00 EDT 2023
ZNFX1 antisense RNA1 promotes antiviral innate immune responses via modulating ZNFX1 function.
Journal of medical virology
Jia X,Zhang M,Wang H,Cheng C,Li Q,Li Y,Kong L,Lan X,Wang Y,Liang X,Yuan S,Wang Y,Xu A
Wed Mar 01 00:00:00 EST 2023
Dexmedetomidine attenuates airway inflammation and oxidative stress in asthma via the Nrf2 signaling pathway.
Molecular medicine reports
Xiao S,Zhou Y,Gao H,Yang D
Sun Jan 01 00:00:00 EST 2023
Aberrant Activation of the STING-TBK1 Pathway in γδ T Cells Regulates Immune Responses in Oral Lichen Planus.
Biomedicines
Huang S,Tan YQ,Zhou G
Mon Mar 20 00:00:00 EDT 2023
Slc6a13 Deficiency Attenuates Pasteurella multocida Infection-Induced Inflammation via Glycine-Inflammasome Signaling.
Journal of innate immunity
He F,Qiu Y,Wu X,Xia Y,Yang L,Wu C,Li P,Zhang R,Fang R,Li N,Peng Y
Tue Dec 26 00:00:00 EST 2023
Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.
Autophagy
Wang SM,Wu HE,Yasui Y,Geva M,Hayden M,Maurice T,Cozzolino M,Su TP
Sun Jan 01 00:00:00 EST 2023
Effect of STK3 on proliferation and apoptosis of pancreatic cancer cells via PI3K/AKT/mTOR pathway.
Cellular signalling
Chen J,Liu F,Wu J,Yang Y,He J,Wu F,Yang K,Li J,Jiang Z,Jiang Z
Thu Jun 01 00:00:00 EDT 2023
NONO regulates B-cell development and B-cell receptor signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang Y,Cui D,Huang M,Zheng Y,Zheng B,Chen L,Chen Q
Sat Apr 01 00:00:00 EDT 2023
Newcastle Disease Virus Manipulates Mitochondrial MTHFD2-Mediated Nucleotide Metabolism for Virus Replication.
Journal of virology
Tang N,Chen P,Zhao C,Liu P,Tan L,Song C,Qiu X,Liao Y,Liu X,Luo T,Sun Y,Ding C
Thu Mar 30 00:00:00 EDT 2023
Amelioration of Lung Fibrosis by Total Flavonoids of Astragalus via Inflammatory Modulation and Epithelium Regeneration.
The American journal of Chinese medicine
Yang CG,Mao XL,Wu JF,An X,Cao JJ,Zhang XY,Li M,Zhang FF
Fri Mar 31 00:00:00 EDT 2023
RASSF1A inhibits epithelial-mesenchymal transition of gastric cancer cells by downregulating P-JNK.
Cell biology international
Bin Y,Deng W,Hu H,Zeng Q,Chen J,Xu Y,Dai Y,Liao A,Xiao W
Wed Mar 01 00:00:00 EST 2023
RBM24 inhibits the translation of SARS-CoV-2 polyproteins by targeting the 5'-untranslated region.
Antiviral research
Yao Y,Sun H,Chen Y,Tian L,Huang D,Liu C,Zhou Y,Wang Y,Wen Z,Yang B,Chen X,Pei R
Sun Jan 01 00:00:00 EST 2023
Relationship between IL-22 and IL-22BP in diabetic cognitive dysfunction.
Acta diabetologica
Wang X,Yu S,Liu W,Lv P,Zhao L,Wang Y,Fu C,Meng L,Yang Q,Wang X,Huang Y,Zuo Z,Liu X
Mon May 01 00:00:00 EDT 2023
Identification and characterization of novel carboxyl ester lipase gene variants in patients with different subtypes of diabetes.
BMJ open diabetes research & care
Wu H,Shu M,Liu C,Zhao W,Li Q,Song Y,Zhang T,Chen X,Shi Y,Shi P,Fang L,Wang R,Xu C
Sun Jan 01 00:00:00 EST 2023
In situ isolation of nuclei or nuclear proteins from adherent cells: a simple, effective method with less cytoplasmic contamination.
Biological research
Qin Y,Zhou Y,Wang K,Gu J,Xiong Z,Zhang W,Chen Y
Fri Apr 21 00:00:00 EDT 2023
SARS-CoV-2 Omicron subvariants exhibit distinct fusogenicity, but similar sensitivity, to pan-CoV fusion inhibitors.
Emerging microbes & infections
Xia S,Wang L,Jiao F,Yu X,Xu W,Huang Z,Li X,Wang Q,Zhu Y,Man Q,Jiang S,Lu L
Fri Dec 01 00:00:00 EST 2023
Mitochondrial division inhibitor (mdivi-1) inhibits proliferation and epithelial-mesenchymal transition via the NF-κB pathway in thyroid cancer cells.
Toxicology in vitro : an international journal published in association with BIBRA
Zhang L,Sun L,Wang L,Wang J,Wang D,Jiang J,Zhang J,Zhou Q
Sat Apr 01 00:00:00 EDT 2023
Uridine Alleviates Sepsis-Induced Acute Lung Injury by Inhibiting Ferroptosis of Macrophage.
International journal of molecular sciences
Lai K,Song C,Gao M,Deng Y,Lu Z,Li N,Geng Q
Tue Mar 07 00:00:00 EST 2023
Photobiomodulation augments the effects of mitochondrial transplantation in the treatment of spinal cord injury in rats by facilitating mitochondrial transfer to neurons via Connexin 36.
Bioengineering & translational medicine
Zhu Z,Li X,Wang X,Zuo X,Ma Y,Gao X,Liang Z,Zhang Z,Song Z,Ding T,Ju C,Li P,Li K,Zhang J,Quan H,Wang Z,Hu X
Mon May 01 00:00:00 EDT 2023
METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.
Journal of experimental & clinical cancer research : CR
Wei W,Zhang ZY,Shi B,Cai Y,Zhang HS,Sun CL,Fei YF,Zhong W,Zhang S,Wang C,He B,Jiang GM,Wang H
Tue Jun 20 00:00:00 EDT 2023
Rapamycin Inhibits Osteoclastogenesis and Prevents LPS-Induced Alveolar Bone Loss by Oxidative Stress Suppression.
ACS omega
Feng C,Liu Y,Zhang BY,Zhang H,Shan FY,Li TQ,Zhao ZN,Wang XX,Zhang XY
Tue Jun 13 00:00:00 EDT 2023
Hexokinase 2-mediated glycolysis supports inflammatory responses to Porphyromonas gingivalis in gingival fibroblasts.
BMC oral health
Su W,Li J,Jiang L,Lei L,Li H
Wed Feb 15 00:00:00 EST 2023
Engineered Extracellular Vesicle-Delivered CRISPR/CasRx as a Novel RNA Editing Tool.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Li T,Zhang L,Lu T,Zhu T,Feng C,Gao N,Liu F,Yu J,Chen K,Zhong J,Tang Q,Zhang Q,Deng X,Ren J,Zeng J,Zhou H,Zhu J
Sat Apr 01 00:00:00 EDT 2023
The Construction and Immunogenicity Analyses of a Recombinant Pseudorabies Virus with Senecavirus A VP2 Protein Coexpression.
Microbiology spectrum
Tao Q,Zhu L,Xu L,Yang Y,Zhang Y,Liu Z,Xu T,Wen J,Deng L,Zhou Y,Xu Z
Tue Mar 28 00:00:00 EDT 2023
High-cholesterol diet promotes depression- and anxiety-like behaviors in mice by impact gut microbe and neuroinflammation.
Journal of affective disorders
Zou L,Tian Y,Wang Y,Chen D,Lu X,Zeng Z,Chen Z,Lin C,Liang Y
Fri Apr 14 00:00:00 EDT 2023
PVT1/miR-136/Sox2/UPF1 axis regulates the malignant phenotypes of endometrial cancer stem cells.
Cell death & disease
Li Q,Kong F,Cong R,Ma J,Wang C,Ma X
Fri Mar 03 00:00:00 EST 2023
Vimar/RAP1GDS1 promotes acceleration of brain aging after flies and mice reach middle age.
Communications biology
Xiong Y,Cheng Q,Li Y,Han Y,Sun X,Liu L
Sat Apr 15 00:00:00 EDT 2023
Angelica sinensis aboveground part polysaccharide and its metabolite 5-MT ameliorate colitis via modulating gut microbiota and TLR4/MyD88/NF-κB pathway.
International journal of biological macromolecules
Zou YF,Li CY,Fu YP,JiZe XP,Zhao YZ,Peng X,Wang JY,Yin ZQ,Li YP,Song X,Li LX,Zhao XH,Feng B,Huang C,Ye G,Tang HQ,Chen J,Li R,Chen XF,Tian ML
Sat Jul 01 00:00:00 EDT 2023
The role of atypical MAP kinase 4 in the host interaction with Cryptosporidium parvum.
Scientific reports
Watanabe N,Bando H,Murakoshi F,Sakurai R,Kabir MHB,Fukuda Y,Kato K
Thu Jan 19 00:00:00 EST 2023
Resveratrol induces proliferation and differentiation of mouse pre-osteoblast MC3T3-E1 by promoting autophagy.
BMC complementary medicine and therapies
Cai W,Sun B,Song C,Liu F,Wu Z,Liu Z
Fri Apr 14 00:00:00 EDT 2023
Repetitive Transcranial Magnetic Stimulation Improves Depression-like Behavior in Rats by Promoting Neural Stem Cell Proliferation and Differentiation.
Neuroscience
Jiang C,Zheng S,Chen T,Li W,Zhang C,Gu S,Ren H,Song J,Zhang Z
Tue Aug 01 00:00:00 EDT 2023
JFD, a Novel Natural Inhibitor of Keap1 Alkylation, Suppresses Intracellular Mycobacterium Tuberculosis Growth through Keap1/Nrf2/SOD2-Mediated ROS Accumulation.
Oxidative medicine and cellular longevity
Wan H,Cai Y,Xiao L,Ling Y,Ge L,Mo S,Xie Q,Peng S,Zhou B,Zeng X,Chen X
Tue Jan 23 00:00:00 EST 2024
An animal model induced by bilateral cavernous nerve crushing mimics post-radical prostatectomy erectile dysfunction in old rats.
Life sciences
Ge Y,Hu D,Xi Y,Wang H,Xia T,Chen J,Pu X,Xiao H
Sat Jul 15 00:00:00 EDT 2023
Highly pathogenic porcine reproductive and respiratory syndrome virus-induced inflammatory response in porcine pulmonary microvascular endothelial cells and effects of herbal ingredients on main inflammatory molecules.
International immunopharmacology
Wu Y,Song X,Li P,Wang Z,Zhao Z,Zhang T
Mon May 01 00:00:00 EDT 2023
Identification of menaquinone-4 (vitamin K2) target genes in bovine endometrial epithelial cells in vitro.
Theriogenology
Bai H,Kawahara M,Takahashi M
Wed Mar 01 00:00:00 EST 2023
Oligomeric Aβ25-35 induces the tyrosine phosphorylation of PSD-95 by SrcPTKs in rat hippocampal CA1 subfield.
The International journal of neuroscience
Wu GM,Du CP,Xu Y
Fri Dec 01 00:00:00 EST 2023
FOXA2 plays a critical role in hepatocellular carcinoma progression and lenvatinib-associated drug resistance.
Bioscience trends
Wang Z,Shen J,Chen C,Wen T,Li C
Mon May 15 00:00:00 EDT 2023
Prevention of Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice by Bilobalide.
Evidence-based complementary and alternative medicine : eCAM
Zhang X,Zhang W,Chen X,Cai Y
Sat Feb 04 00:00:00 EST 2023
Ubiquitin E3 ligase β-TrCP negatively regulates surface protein of hepatitis B virus.
Journal of medical virology
Tu W,Liu J,Qian F,Zhu L,Li M,Zheng H,Zhu C
Wed Mar 01 00:00:00 EST 2023
Exosomal microRNA-4535 of Melanoma Stem Cells Promotes Metastasis by Inhibiting Autophagy Pathway.
Stem cell reviews and reports
Liu D,Li X,Zeng B,Zhao Q,Chen H,Zhang Y,Chen Y,Wang J,Xing HR
Sun Jan 01 00:00:00 EST 2023
CCP1, a Regulator of Tubulin Post-Translational Modifications, Potentially Plays an Essential Role in Cerebellar Development.
International journal of molecular sciences
Pang B,Araki A,Zhou L,Takebayashi H,Harada T,Kadota K
Fri Mar 10 00:00:00 EST 2023
Long noncoding RNA uc007nnj.1 mediates neuronal death induced by retinal ischemia/reperfusion in mice via the miR-155-5p/Tle4 axis.
Molecular medicine (Cambridge, Mass.)
Feng Y,Lu J,Peng X,Ge Y,Zhang R,Li H
Wed Jan 18 00:00:00 EST 2023
Low temperature exposure inhibits proliferation and induces apoptosis of bovine subcutaneous preadipocytes via p38 MAPK/JNK activation.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology
Li T,Bai H,Yang L,Hao W,Wei S,Yan P
Tue Dec 20 00:00:00 EST 2022
GBP2 promotes clear cell renal cell carcinoma progression through immune infiltration and regulation of PD‑L1 expression via STAT1 signaling.
Oncology reports
Ye S,Li S,Qin L,Zheng W,Liu B,Li X,Ren Z,Zhao H,Hu X,Ye N,Li G
Wed Mar 01 00:00:00 EST 2023
Chloride intracellular channel 1 promotes esophageal squamous cell carcinoma proliferation via mTOR signalling.
Translational oncology
Geng H,Feng C,Sun Z,Fan X,Xie Y,Gu J,Fan L,Liu G,Li C,Thorne RF,Zhang XD,Li X,Liu X
Sun Jan 01 00:00:00 EST 2023
Multi-omics analysis of a drug-induced model of bipolar disorder in zebrafish.
iScience
Li Y,Zhang L,Mao M,He L,Wang T,Pan Y,Zhao X,Li Z,Mu X,Qian Y,Qiu J
Fri May 19 00:00:00 EDT 2023
CM3-SII polysaccharide obtained from Cordyceps militaris ameliorates hyperlipidemia in heterozygous LDLR-deficient hamsters by modulating gut microbiota and NPC1L1 and PPARα levels.
International journal of biological macromolecules
Yu WQ,Wang XL,Ji HH,Miao M,Zhang BH,Li H,Zhang ZY,Ji CF,Guo SD
Thu Jun 01 00:00:00 EDT 2023
10-Gingerol Enhances the Effect of Taxol in Triple-Negative Breast Cancer via Targeting ADRB2 Signaling.
Drug design, development and therapy
Liang Y,Wu G,Luo T,Xie H,Zuo Q,Huang P,Li H,Chen L,Lu H,Chen Q
Wed Feb 01 00:00:00 EST 2023
6-Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF-7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling pathway.
Phytotherapy research : PTR
Zhang L,Zhang X,Che D,Zeng L,Zhang Y,Nan K,Zhang X,Zhang H,Guo Z
Sun Jan 01 00:00:00 EST 2023
LPS inhibits TRIM65 expression in macrophages and C57BL/6J mouse by activating the ERK1/2 signaling pathway.
Experimental and therapeutic medicine
Zeng X,Deng X,Ni Y,Bi H,Jiang M,Wang D,Dong P,Xiao Y,Jiang M
Sat Apr 01 00:00:00 EDT 2023
Study on the treatment of postmenopausal osteoporosis with quercetin in Liuwei Dihuang Pill based on network pharmacology.
Journal of orthopaedic surgery and research
Zhu F,Li W,Wang L,Dai B,Liu Z,Wu H,Deng T
Mon Jan 09 00:00:00 EST 2023
Effect of acupuncture on the opening time of implantation window and endometrial receptivity in controlled ovarian hyperstimulation rats during peri-implantation period.
Frontiers in endocrinology
Hu R,Huang Y,Song Y,Wu X,Song K,Huang G,Zhang M,Dong H
Tue Apr 04 00:00:00 EDT 2023
PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism.
iScience
Xue T,Zhao S,Zhang H,Tang T,Zheng L,Jing J,Ge X,Ma R,Ma J,Ren X,Jueraitetibaike K,Guo Z,Chen L,Yao B
Fri Mar 17 00:00:00 EDT 2023
LncRNA CFAR promotes cardiac fibrosis via the miR-449a-5p/LOXL3/mTOR axis.
Science China. Life sciences
Zhang M,Zhang B,Wang X,Song J,Tong M,Dong Z,Xu J,Liu M,Jiang Y,Wang N,Wang Y,Du Z,Liu Y,Zhang R,Xu C
Sat Apr 01 00:00:00 EDT 2023
Elevated nuclear TDP-43 induces constitutive exon skipping.
bioRxiv : the preprint server for biology
Carmen-Orozco RP,Tsao W,Ye Y,Sinha IR,Chang K,Trinh V,Chung W,Bowden K,Troncoso JC,Blackshaw S,Hayes LR,Sun S,Wong PC,Ling JP
Fri May 12 00:00:00 EDT 2023
CircHIPK3 negatively regulates autophagy by blocking VCP binding to the Beclin 1 complex in bladder cancer.
Discover. Oncology
Wang C,Liu T,Wang J,Cheng C,Zhang Z,Zhang J,Huang H,Li Y
Sat Jun 03 00:00:00 EDT 2023
Phenolic profile, antioxidation and anti-proliferation activity of phenolic-rich extracts from Sanghuangporusvaninii.
Current research in food science
Gao H,Yin C,Li C,Li Y,Shi D,Fan X,Yao F,Wu W,Li J
Sun Jun 04 00:00:00 EDT 2023
Whether the Subacute MPTP-Treated Mouse is as Suitable as a Classic Model of Parkinsonism.
Neuromolecular medicine
Qi Y,Zhang Z,Li Y,Zhao G,Huang J,Zhang Y,Xue J,Tang X
Fri Sep 01 00:00:00 EDT 2023
Microglia activation mediates circadian rhythm disruption-induced cognitive impairment in mice.
Journal of neuroimmunology
Meng D,Yang M,Zhang H,Zhang L,Song H,Liu Y,Zeng Y,Yang B,Wang X,Chen Y,Liu R
Thu Jun 15 00:00:00 EDT 2023
ZSWIM1 Promotes the Proliferation and Metastasis of Lung Adenocarcinoma Cells through the STK38/MEKK2/ERK1/2 Axis.
Journal of proteome research
Gao X,Lian Q,Guan B,Liu QY,Meng M,Chen Y,Jin J,Li H,Liu X,Sun Z,Liu L,He QY,Zhang G
Fri Apr 07 00:00:00 EDT 2023
Role of Escin in breast cancer therapy: potential mechanism for inducing ferroptosis and synergistic antitumor activity with cisplatin.
Apoptosis : an international journal on programmed cell death
Li C,He Z,Yao F,Liao S,Sun K,Sun S,Li Z,Wang Z
Tue Aug 01 00:00:00 EDT 2023
N6-methyladenosine-modified USP13 induces pro-survival autophagy and imatinib resistance via regulating the stabilization of autophagy-related protein 5 in gastrointestinal stromal tumors.
Cell death and differentiation
Gao Z,Li C,Sun H,Bian Y,Cui Z,Wang N,Wang Z,Yang Y,Liu Z,He Z,Li B,Li F,Li Z,Wang L,Zhang D,Yang L,Xu Z,Li X,Xu H
Wed Feb 01 00:00:00 EST 2023
The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression.
Experimental & molecular medicine
Yan B,Li X,Peng M,Zuo Y,Wang Y,Liu P,Ren W,Jin X
Thu Jun 01 00:00:00 EDT 2023
Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.
Placenta
Yuan D,Guo T,Qian H,Jin C,Ge H,Zhao Y,Zhu D,Lin M,Wang H,Yu H
Sun Jan 01 00:00:00 EST 2023
miR-34b-3p Inhibition of eIF4E Causes Post-stroke Depression in Adult Mice.
Neuroscience bulletin
Ke X,Deng M,Wu Z,Yu H,Yu D,Li H,Lu Y,Shu K,Pei L
Wed Feb 01 00:00:00 EST 2023
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhao Z,Du JF,Wang QL,Qiu FN,Chen XY,Liu FJ,Li P,Jiang Y,Li HJ
Thu Jun 01 00:00:00 EDT 2023
An integrated strategy combining network toxicology and feature-based molecular networking for exploring hepatotoxic constituents and mechanism of Epimedii Folium-induced hepatotoxicity in vitro.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhao Z,Du JF,Wang QL,Qiu FN,Chen XY,Liu FJ,Li P,Jiang Y,Li HJ
Thu Jun 01 00:00:00 EDT 2023
Characterizing the specific mechanism of series processed Coptidis Rhizoma by multi-organ metabolomics combined with network pharmacology and molecular docking.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhou N,Wang Y,Zhang Z,Feng W,Liu T,Cao Y,Zhang J,Zhang B,Zheng X,Li K
Thu Jun 01 00:00:00 EDT 2023
TIM-4 orchestrates mitochondrial homeostasis to promote lung cancer progression via ANXA2/PI3K/AKT/OPA1 axis.
Cell death & disease
Wang Y,Wang Y,Liu W,Ding L,Zhang X,Wang B,Tong Z,Yue X,Li C,Xu L,Wu Z,Liang X,Ma C,Gao L
Mon Feb 20 00:00:00 EST 2023
Ponicidin Induces Apoptosis of Murine Melanoma by Inhibiting the NF-κB Signaling Pathway.
Biological & pharmaceutical bulletin
Wang L,Lou X,Wang D,Lu K,Zhang S,Cheng B
Fri Jun 02 00:00:00 EDT 2023
Potential targets and mechanisms of photobiomodulation for spinal cord injury.
Neural regeneration research
Ju C,Ma YG,Zuo XS,Wang XK,Song ZW,Zhang ZH,Zhu ZJ,Li X,Liang ZW,Ding T,Wang Z,Hu XY
Tue Aug 01 00:00:00 EDT 2023
Anomanolide C suppresses tumor progression and metastasis by ubiquitinating GPX4-driven autophagy-dependent ferroptosis in triple negative breast cancer.
International journal of biological sciences
Chen YM,Xu W,Liu Y,Zhang JH,Yang YY,Wang ZW,Sun DJ,Li H,Liu B,Chen LX
Wed May 24 00:00:00 EDT 2023
TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis.
The Journal of clinical investigation
Huang C,Zhao S,Yang Y,Guo T,Ke H,Mi X,Qin Y,Chen ZJ,Zhao S
Wed Mar 01 00:00:00 EST 2023
Transcription factor SOX15 regulates stem cell pluripotency and promotes neural fate during differentiation by activating the neurogenic gene Hes5.
The Journal of biological chemistry
Choi EB,Vodnala M,Saini P,Anugula S,Zerbato M,Ho JJ,Wang J,Ho Sui SJ,Yoon J,Roels M,Inouye C,Fong YW
Wed Mar 01 00:00:00 EST 2023
CircRNA-02191 regulating unsaturated fatty acid synthesis by adsorbing miR-145 to enhance CD36 expression in bovine mammary gland.
International journal of biological macromolecules
Chen Z,Wang Y,Wang K,Zhang Z,Han M,Li G,Zhang B,Yang Y,Loor JJ,Yang Z,Zhong F,Dai R,Wang M
Mon Jul 31 00:00:00 EDT 2023
In vitro and in vivo study on the treatment of non-small cell lung cancer with radionuclide labeled PD-L1 nanobody.
Journal of cancer research and clinical oncology
Zhu M,Zhang J,Yang M,Zhang H,Xu T,Kan F,Zhang X,Zhang S,Yin Y,Yu F
Fri Sep 01 00:00:00 EDT 2023
Fc receptor-like 1 (FCRL1) is a novel biomarker for prognosis and a possible therapeutic target in diffuse large B-cell lymphoma.
Molecular biology reports
Yousefi Z,Sharifzadeh S,Zare F,Eskandari N
Wed Feb 01 00:00:00 EST 2023
The relationship between gut microbiota and susceptibility to type 2 diabetes mellitus in rats.
Chinese medicine
An Y,Dai H,Duan Y,Cheng L,Shi L,He C,Wang C,Lv Y,Li H,Zhang H,Huang Y,Fu W,Sun W,Zhao B
Fri May 05 00:00:00 EDT 2023
Ergolide covalently binds NLRP3 and inhibits NLRP3 inflammasome-mediated pyroptosis.
International immunopharmacology
Ren M,Chen J,Xu H,Li W,Wang T,Chi Z,Lin Y,Zhang A,Chen G,Wang X,Sun X,Liang G,Wang J,Luo W
Sat Jul 01 00:00:00 EDT 2023
Targeting ZDHHC9 potentiates anti-programmed death-ligand 1 immunotherapy of pancreatic cancer by modifying the tumor microenvironment.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lin Z,Huang K,Guo H,Jia M,Sun Q,Chen X,Wu J,Yao Q,Zhang P,Vakal S,Zou Z,Gao H,Ci L,Chen J,Guo W
Mon May 01 00:00:00 EDT 2023
SARS-CoV-2 Omicron XBB subvariants exhibit enhanced fusogenicity and substantial immune evasion in elderly population, but high sensitivity to pan-coronavirus fusion inhibitors.
Journal of medical virology
Xia S,Jiao F,Wang L,Yu X,Lu T,Fu Y,Huang Z,Li X,Huang J,Wang Q,Man Q,Xiong L,Jiang S,Lu L
Wed Mar 01 00:00:00 EST 2023
POU Domain Class 2 Transcription Factor 2 Inhibits Ferroptosis in Cerebral Ischemia Reperfusion Injury by Activating Sestrin2.
Neurochemical research
Yang J,Guo Q,Wang L,Yu S
Wed Feb 01 00:00:00 EST 2023
Quantitative proteomics of sperm tail in asthenozoospermic patients: exploring the molecular pathways affecting sperm motility.
Cell and tissue research
Mirshahvaladi S,Topraggaleh TR,Bucak MN,Rahimizadeh P,Shahverdi A
Thu Jun 01 00:00:00 EDT 2023
M2 macrophages with inflammation tropism facilitate cementoblast mineralization.
Journal of periodontology
Huang X,Wang X,Ma L,Wang H,Peng Y,Liu H,Xiao J,Cao Z
Wed Feb 01 00:00:00 EST 2023
Disruption of the Intestinal Mucosal Barrier Induced by High Fructose and Restraint Stress Is Regulated by the Intestinal Microbiota and Microbiota Metabolites.
Microbiology spectrum
Yu J,Liu T,Guo Q,Wang Z,Chen Y,Dong Y
Tue Jan 31 00:00:00 EST 2023
VASN promotes colorectal cancer progression by activating the YAP/TAZ and AKT signaling pathways via YAP.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liang W,Zuo J,Liu M,Su Y,Guo B,Hou J,Xing Q,Peng Y,Fang L,Cao Y,Shan J,Sun R,Zhao J,Wang J
Sun Jan 01 00:00:00 EST 2023
cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway.
Journal of immunology (Baltimore, Md. : 1950)
Shen X,Sun C,Cheng Y,Ma D,Sun Y,Lin Y,Zhao Y,Yang M,Jing W,Cui X,Han L
Sat Apr 15 00:00:00 EDT 2023
Modified Gegen Qinlian decoction ameliorated ulcerative colitis by attenuating inflammation and oxidative stress and enhancing intestinal barrier function in vivo and in vitro.
Journal of ethnopharmacology
Wang Y,Zhang J,Zhang B,Lu M,Ma J,Liu Z,Huang J,Ma J,Yang X,Wang F,Tang X
Fri Sep 15 00:00:00 EDT 2023
Nutrient-dependent regulation of β-cell proinsulin content.
The Journal of biological chemistry
Xu X,Arunagiri A,Alam M,Haataja L,Evans CR,Zhao I,Castro-Gutierrez R,Russ HA,Demangel C,Qi L,Tsai B,Liu M,Arvan P
Sat Jul 01 00:00:00 EDT 2023
Microbiota from Exercise Mice Counteracts High-Fat High-Cholesterol Diet-Induced Cognitive Impairment in C57BL/6 Mice.
Oxidative medicine and cellular longevity
Li R,Liu R,Chen L,Wang G,Qin L,Yu Z,Wan Z
Wed Feb 01 00:00:00 EST 2023
C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways.
Journal of applied oral science : revista FOB
Chen Y,Liu Y,Li H,Huna R,Tan X,Li N,Zhang Y,Jiao X,Liu M
Fri Feb 10 00:00:00 EST 2023
Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner.
Molecular medicine (Cambridge, Mass.)
Chen Y,Liu X,Li L,He X,Zheng F,Zhang Y,Gao H,Jin Z,Wu D,Wang Q,Tao H,Zhao Y,Liu W,Zou L
Mon Feb 06 00:00:00 EST 2023
Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model.
Journal of extracellular vesicles
Chen Y,Ou Z,Pang M,Tao Z,Zheng X,Huang Z,Wen D,Li Q,Zhou R,Chen P,Situ B,Sheng C,Huang Y,Yue X,Zheng L,Huang L
Mon May 01 00:00:00 EDT 2023
Chemo- and Diastereoselective Cycloisomerization/[2 + 3] Cycloaddition of Enynamides: Synthesis of Spiropyrazolines as Potential Anticancer Reagents.
The Journal of organic chemistry
Fang H,Li Y,Zhang L,Yan ZH,Ma K,Peng C,Huang W,Zhan G
Fri Jun 02 00:00:00 EDT 2023
PSKH1 affects proliferation and invasion of osteosarcoma cells via the p38/MAPK signaling pathway.
Oncology letters
Zhu X,Jiang C,Wang Z,Zhu X,Yuan F,Yang Y
Sat Apr 01 00:00:00 EDT 2023
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Molecular oncology
Luo G,Aldridge K,Chen T,Aslot V,Kim BG,Han EH,Singh N,Li S,Xiao TS,Sporn MB,Letterio JJ
Fri Dec 01 00:00:00 EST 2023
Berberine inhibits high fat diet-associated colorectal cancer through modulation of the gut microbiota-mediated lysophosphatidylcholine.
International journal of biological sciences
Chen H,Ye C,Wu C,Zhang J,Xu L,Wang X,Xu C,Zhang J,Guo Y,Yao Q
Tue May 09 00:00:00 EDT 2023
Bile duct ligation increased dopamine levels in the cerebral cortex of rats partly due to induction of tyrosine hydroxylase.
British journal of pharmacology
Kong W,Sun X,Yu S,Liu P,Zheng X,Zhang J,Zhu L,Jiang T,Jin M,Gao J,Fan X,Liu X,Liu L
Sat Jul 01 00:00:00 EDT 2023
Microglia PKM2 Mediates Neuroinflammation and Neuron Loss in Mice Epilepsy through the Astrocyte C3-Neuron C3R Signaling Pathway.
Brain sciences
Li X,Zhou R,Peng H,Peng J,Li Q,Mei M
Fri Feb 03 00:00:00 EST 2023
The natural flavone acacetin protects against high-fat diet-induced lipid accumulation in the liver via the endoplasmic reticulum stress/ferroptosis pathway.
Biochemical and biophysical research communications
Jiang Z,Sun H,Miao J,Sheng Q,Xu J,Gao Z,Zhang X,Song Y,Chen K
Sun Jan 15 00:00:00 EST 2023
Knockdown of the long non‑coding RNA MALAT1 ameliorates TNF‑α‑mediated endothelial cell pyroptosis via the miR‑30c‑5p/Cx43 axis.
Molecular medicine reports
Yang ZJ,Liu R,Han XJ,Qiu CL,Dong GL,Liu ZQ,Liu LH,Luo Y,Jiang LP
Sat Apr 01 00:00:00 EDT 2023
Cathepsin B S-nitrosylation promotes ADAR1-mediated editing of its own mRNA transcript via an ADD1/MATR3 regulatory axis.
Cell research
Lin Z,Zhao S,Li X,Miao Z,Cao J,Chen Y,Shi Z,Zhang J,Wang D,Chen S,Wang L,Gu A,Chen F,Yang T,Sun K,Han Y,Xie L,Chen H,Ji Y
Sat Jul 01 00:00:00 EDT 2023
Chronic spinal cord compression associated with intervertebral disc degeneration in SPARC-null mice.
Neural regeneration research
Li ZY,Zhou AF,Li G,Zhou LY,Pu PM,Zhu K,Zheng Z,Wang YJ,Liang QQ,Yao M,Cui XJ
Wed Mar 01 00:00:00 EST 2023
Qingre Huazhuo Jiangsuan Decoction promotes autophagy by inhibiting PI3K/AKT/mTOR signaling pathway to relieve acute gouty arthritis.
Journal of ethnopharmacology
Liu P,Xu Y,Ye J,Tan J,Hou J,Wang Y,Li J,Cui W,Wang S,Zhao Q
Fri Feb 10 00:00:00 EST 2023
A Mulberry Diels-Alder-Type Adduct, Kuwanon M, Triggers Apoptosis and Paraptosis of Lung Cancer Cells through Inducing Endoplasmic Reticulum Stress.
International journal of molecular sciences
Ma M,Luan X,Zheng H,Wang X,Wang S,Shen T,Ren D
Thu Jan 05 00:00:00 EST 2023
ARID1B blocks methionine-stimulated mTOR activation to inhibit milk fat and protein synthesis in and proliferation of mouse mammary epithelial cells.
The Journal of nutritional biochemistry
Lin G,Qi H,Guo X,Wang W,Zhang M,Gao X
Sat Apr 01 00:00:00 EDT 2023
Role of asparagine biosynthesis pathway in Siniperca chuatsi rhabdovirus proliferation.
Frontiers in microbiology
Li F,Fu X,Luo X,Lin Q,Liang H,Niu Y,Liu L,Li N
Tue Apr 18 00:00:00 EDT 2023
PHB2 promotes colorectal cancer cell proliferation and tumorigenesis through NDUFS1-mediated oxidative phosphorylation.
Cell death & disease
Ren L,Meng L,Gao J,Lu M,Guo C,Li Y,Rong Z,Ye Y
Fri Jan 20 00:00:00 EST 2023
FZD7, Regulated by Non-CpG Methylation, Plays an Important Role in Immature Porcine Sertoli Cell Proliferation.
International journal of molecular sciences
Yang A,Yan S,Yin Y,Chen C,Tang X,Ran M,Chen B
Fri Mar 24 00:00:00 EDT 2023
Protective Effect of 20(S)-Protopanaxadiol on D-Gal-Induced Cognitively Impaired Mice Based on Its Target Protein Brain-type Creatine Kinase.
Journal of agricultural and food chemistry
Zhang H,Chen F,Xu S,Zhang W,Li R,Yao Q,Zhao Y,Zhu Z,Chen L
Wed Feb 08 00:00:00 EST 2023
Anti-inflammatory effects of extracellular vesicles from Morchella on LPS-stimulated RAW264.7 cells via the ROS-mediated p38 MAPK signaling pathway.
Molecular and cellular biochemistry
Chen Q,Che C,Yang S,Ding P,Si M,Yang G
Wed Feb 01 00:00:00 EST 2023
Stromal cell-derived small extracellular vesicles enhance radioresistance of prostate cancer cells via interleukin-8-induced autophagy.
Journal of extracellular vesicles
Wang X,Xu F,Kou H,Zheng Y,Yang J,Xu Z,Fang Y,Sun W,Zhu S,Jiang Q,Wei X,Xu Y
Sat Jul 01 00:00:00 EDT 2023
Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination.
Journal of neuroinflammation
Wang Y,Sun J,Zhu K,Wang D,Zhao X,Zhang H,Wu S,Wang Y,Wang J
Sat Mar 25 00:00:00 EDT 2023
KIAA1199 promotes oxaliplatin resistance and epithelial mesenchymal transition of colorectal cancer via protein O-GlcNAcylation.
Translational oncology
Hua Q,Lu Y,Wang D,Da J,Peng W,Sun G,Gu K,Wang H,Zhu Y
Wed Feb 01 00:00:00 EST 2023
Metabolism-related lncRNAs signature to predict the prognosis of colon adenocarcinoma.
Cancer medicine
Sun Y,Liu B,Xiao B,Jiang X,Xiang JJ,Xie J,Hu XM
Wed Mar 01 00:00:00 EST 2023
Tax1 binding protein 3 regulates osteogenic and adipogenic differentiation through inactivating Wnt/β-catenin signalling.
Journal of cellular and molecular medicine
Wang Y,Gan Y,Dong Y,Zhou J,Zhu E,Yuan H,Li X,Wang B
Sat Apr 01 00:00:00 EDT 2023
TIGAR deficiency induces caspase-1-dependent trophoblasts pyroptosis through NLRP3-ASC inflammasome.
Frontiers in immunology
Guo J,Zhou M,Zhao M,Li S,Fang Z,Li A,Zhang M
Tue May 02 00:00:00 EDT 2023
SDC1-dependent TGM2 determines radiosensitivity in glioblastoma by coordinating EPG5-mediated fusion of autophagosomes with lysosomes.
Autophagy
Zheng W,Chen Q,Liu H,Zeng L,Zhou Y,Liu X,Bai Y,Zhang J,Pan Y,Shao C
Wed Mar 01 00:00:00 EST 2023
The role of Sirt3-induced autophagy in renal structural damage caused by periodontitis in rats.
Journal of periodontal research
Ding X,Hou Y,Liu X,Li X,Liu X,Deng Y,Cao N,Yu W
Wed Feb 01 00:00:00 EST 2023
A role of cytoplasmic p53 in the regulation of metabolism shown by bat-mimicking p53 NLS mutant mice.
Cell reports
Sanford JD,Jin A,Grois GA,Zhang Y
Tue Jan 31 00:00:00 EST 2023
SNORD60 promotes the tumorigenesis and progression of endometrial cancer through binding PIK3CA and regulating PI3K/AKT/mTOR signaling pathway.
Molecular carcinogenesis
Wu W,Chen X,Liu X,Bao HJ,Li QH,Xian JY,Lu BF,Zhao Y,Chen S
Sat Apr 01 00:00:00 EDT 2023
Isoamericanin A improves lipopolysaccharide-induced memory impairment in mice through suppression of the nicotinamide adenine dinucleotide phosphateoxidase-dependent nuclear factor kappa B signaling pathway.
Phytotherapy research : PTR
Yang Y,Chen R,Che Y,Yao X,Fang M,Wang Y,Zhou D,Li N,Hou Y
Fri Sep 01 00:00:00 EDT 2023
Upregulation of NDUFAF2 in Lung Adenocarcinoma Is a Novel Independent Prognostic Biomarker.
Computational and mathematical methods in medicine
Zou K,Gao P,Xu X,Zhang W,Zeng Z
Mon Jan 30 00:00:00 EST 2023
KLF6 alleviates hepatic ischemia-reperfusion injury by inhibiting autophagy.
Cell death & disease
Li J,Yu D,He C,Yu Q,Huo Z,Zhang Y,Zhang S
Sat Jul 01 00:00:00 EDT 2023
Palmitoyl transferases act as novel drug targets for pancreatic cancer.
Journal of translational medicine
Lin Z,Lv Z,Liu X,Huang K
Mon Apr 10 00:00:00 EDT 2023
Alpinia oxyphylla Miq. volatile oil ameliorates depressive behaviors and inhibits neuroinflammation in CUMS-exposed mice by inhibiting the TLR4-medicated MyD88/NF-κB signaling pathway.
Journal of chemical neuroanatomy
Wu B,Gan A,Wang R,Lin F,Yan T,Jia Y
Sat Jul 01 00:00:00 EDT 2023
Manipulation of PD-L1 Endosomal Trafficking Promotes Anticancer Immunity.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Ye Z,Xiong Y,Peng W,Wei W,Huang L,Yue J,Zhang C,Lin G,Huang F,Zhang L,Zheng S,Yue J
Wed Feb 01 00:00:00 EST 2023
EFEMP1 is a potential biomarker of choroid thickness change in myopia.
Frontiers in neuroscience
Shi WQ,Wan T,Li B,Li T,Zhou XD
Fri Mar 10 00:00:00 EST 2023
Profilin1 Regulates Trophoblast Invasion and Macrophage Differentiation.
The American journal of pathology
Chen X,Song QL,Wang JY,Ji R,Li ZH,Cao ML,Mu XF,Guo DY,Zhang Y,Yang J
Tue Aug 01 00:00:00 EDT 2023
Mitochondrial targeting half-sandwich iridium(III) and ruthenium(II) dppf complexes and in vitro anticancer assay.
Journal of inorganic biochemistry
Liu J,Wu Y,Yang G,Liu Z,Liu X
Wed Feb 01 00:00:00 EST 2023
Ang-(1-7)/MasR axis promotes functional recovery after spinal cord injury by regulating microglia/macrophage polarization.
Cell & bioscience
Gu G,Zhu B,Ren J,Song X,Fan B,Ding H,Shang J,Wu H,Li J,Wang H,Li J,Wei Z,Feng S
Sat Feb 04 00:00:00 EST 2023
Taurochenodeoxycholic acid inhibits intestinal epithelial cell proliferation and induces apoptosis independent of the farnesoid X receptor.
Food & function
Liu Y,Niu K,Wang R,Liang X,Lin C,Wu X,Zhai Z
Tue Jun 06 00:00:00 EDT 2023
A Prevascularized Sinus Tract on the Liver Surface for Islet Transplantation.
Transplantation
Li F,Lv Y,Li X,Yang Z,Guo T,Zhang J
Sun Jan 01 00:00:00 EST 2023
CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer.
The Journal of clinical investigation
Zheng C,Wei Y,Zhang P,Xu L,Zhang Z,Lin K,Hou J,Lv X,Ding Y,Chiu Y,Jain A,Islam N,Malovannaya A,Wu Y,Ding F,Xu H,Sun M,Chen X,Chen Y
Wed Mar 01 00:00:00 EST 2023
Calpain-2 Facilitates Autophagic/Lysosomal Defects and Apoptosis in ARPE-19 Cells and Rats Induced by Exosomes from RPE Cells under NaIO3 Stimulation.
Oxidative medicine and cellular longevity
Zhang S,Qiu Y,Feng Y,Zhang Y,Li Y,Wang B,Wei H,Chen X,Shen L,Li W,Zheng L,Zhang Y
Tue Jan 31 00:00:00 EST 2023
ARID3A plays a key regulatory role in palmitic acid-stimulated milk fat synthesis in mouse mammary epithelial cells.
Cell biology international
Guo X,Qi H,Lin G,Yu J,Zhang M,Gao X
Thu Jun 01 00:00:00 EDT 2023
Cannabinoid type 2 receptor activation inhibits MPP+-induced M1 differentiation of microglia through activating PI3K/Akt/Nrf2 signal pathway.
Molecular biology reports
Wang M,Liu M,Ma Z
Mon May 01 00:00:00 EDT 2023
Exploring the potential of ginseng glycoprotein to improve learning and memory in mice via Notch signaling pathway and structural analysis using multi-information fusion based on liquid chromatography-mass spectrometry.
Journal of ethnopharmacology
Fang X,Zhang X,Zhang Y,Zhang X,Shan M,Guan S,Qiu Z,Zhu D,Luo H
Wed Mar 01 00:00:00 EST 2023
Proline promotes proliferation and drug resistance of multiple myeloma by downregulation of proline dehydrogenase.
British journal of haematology
Zhang J,Shi F,Liu X,Wu X,Hu C,Guo J,Yang Q,Xia J,He Y,An G,Qiu L,Feng X,Zhou W
Mon May 01 00:00:00 EDT 2023
Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases.
International journal of molecular sciences
Liu H,Ma H,Zeng X,Wu C,Acharya S,Sudan SK,Zhang X
Mon Jun 12 00:00:00 EDT 2023
The Circadian System Is Essential for the Crosstalk of VEGF-Notch-mediated Endothelial Angiogenesis in Ischemic Stroke.
Neuroscience bulletin
Zhang Y,Zhao X,Guo C,Zhang Y,Zeng F,Yin Q,Li Z,Shao L,Zhou D,Liu L
Fri Sep 01 00:00:00 EDT 2023
Developmental changes in lipid and fatty acid metabolism and the inhibition by in ovo feeding oleic acid in Muscovy duck embryogenesis.
Animal nutrition (Zhongguo xu mu shou yi xue hui)
Zhang X,Wu Q,Zheng W,Liu C,Huang L,Zuo X,Xiao W,Han X,Ye H,Wang W,Yang L,Zhu Y
Wed Mar 01 00:00:00 EST 2023
Platelets promote CRC by activating the C5a/C5aR1 axis via PSGL-1/JNK/STAT1 signaling in tumor-associated macrophages.
Theranostics
Li X,Chen X,Gong S,Zhao J,Yao C,Zhu H,Xiao R,Qin Y,Li R,Sun N,Li X,Dong F,Zhao T,Pan Y,Yang J
Tue Apr 18 00:00:00 EDT 2023
Hepatic G Protein-Coupled Receptor 180 Deficiency Ameliorates High Fat Diet-Induced Lipid Accumulation via the Gi-PKA-SREBP Pathway.
Nutrients
Zhang Y,Zhu Z,Sun L,Yin W,Liang Y,Chen H,Bi Y,Zhai W,Yin Y,Zhang W
Tue Apr 11 00:00:00 EDT 2023
A copper complex that combats triple negative breast cancer by restraining angiogenesis.
Dalton transactions (Cambridge, England : 2003)
Zheng H,Hu C,Quan Y,Ye X,Shi X,Guo Z,Wang X
Tue Jun 06 00:00:00 EDT 2023
DSTN Hypomethylation Promotes Radiotherapy Resistance of Rectal Cancer by Activating the Wnt/β-Catenin Signaling Pathway.
International journal of radiation oncology, biology, physics
Wen R,Zhou L,Jiang S,Fan H,Zheng K,Yu Y,Gao X,Hao L,Lou Z,Yu G,Yang F,Zhang W
Fri Sep 01 00:00:00 EDT 2023
Thioredoxin 1 overexpression attenuated diabetes-induced endoplasmic reticulum stress in Müller cells via apoptosis signal-regulating kinase 1.
Journal of cellular biochemistry
Yu X,Teng Q,Bao K,Chudhary M,Qi H,Zhou W,Che H,Liu J,Ren X,Kong L
Wed Mar 01 00:00:00 EST 2023
Efficient tumor synergistic chemoimmunotherapy by self-augmented ROS-responsive immunomodulatory polymeric nanodrug.
Journal of nanobiotechnology
Song J,Cheng M,Xie Y,Li K,Zang X
Thu Mar 16 00:00:00 EDT 2023
Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.
The journal of gene medicine
Shao Q,Jiang C,Zhang Q,Liu J,Jin B,Zhao M,Xia Y
Fri Sep 01 00:00:00 EDT 2023
Characterization of TIM-3 Expression and Its Correlation with TNF-α and IFN-γ in Patients with Surgically Resected Lung Adenocarcinoma.
Disease markers
Tan J,Shen P,Yang X,Cai W,Liao H
Tue Mar 07 00:00:00 EST 2023
Neuroprotective effect of meglumine cyclic adenylate against ischemia/reperfusion injury via STAT3-Ser727 phosphorylation.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Niu XQ,Li DD,Bao YJ,Yang Q,Liu YK,Lu F,Yan JZ,Yin XH,Li C
Sun Jan 01 00:00:00 EST 2023
TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Wu M,Jin Q,Xu X,Fan J,Chen W,Miao M,Gu R,Zhang S,Guo Y,Huang S,Zhang Y,Zhang A,Jia Z
Fri Sep 01 00:00:00 EDT 2023
Structure of Semliki Forest virus in complex with its receptor VLDLR.
Cell
Cao D,Ma B,Cao Z,Zhang X,Xiang Y
Thu May 11 00:00:00 EDT 2023
Profiling the metabolome of uterine fluid for early detection of ovarian cancer.
Cell reports. Medicine
Wang P,Ma J,Li W,Wang Q,Xiao Y,Jiang Y,Gu X,Wu Y,Dong S,Guo H,Li M
Tue Jun 20 00:00:00 EDT 2023
Discovery of rafoxanide as a novel agent for the treatment of non-small cell lung cancer.
Scientific reports
Hu A,Liu J,Wang Y,Zhang M,Guo Y,Qin Y,Liu T,Men Y,Chen Q,Liu T
Fri Jan 13 00:00:00 EST 2023
Orai1 is an Entotic Ca2+ Channel for Non-Apoptotic Cell Death, Entosis in Cancer Development.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Lee AR,Park CY
Mon May 01 00:00:00 EDT 2023
Gold nanoparticles inhibit tumor growth via targeting the Warburg effect in a c-Myc-dependent way.
Acta biomaterialia
Sun L,Liu Y,Yang N,Ye X,Liu Z,Wu J,Zhou M,Zhong W,Cao M,Zhang J,Mequanint K,Xing M,Liao W
Wed Mar 01 00:00:00 EST 2023
d-mannose blocks the interaction between keratinocytes and Th17 cells to alleviate psoriasis by inhibiting HIF-1α/CCL20 in mice.
International immunopharmacology
Jiang Q,Wei B,You M,Zhou X
Mon May 01 00:00:00 EDT 2023
Metabolomic analysis and pharmacological validation of the cerebral protective effect of 3,4‑dihydroxybenzaldehyde on cerebral ischemia‑reperfusion injury.
Molecular medicine reports
Luo Y,Chen P,Yang L,Duan X
Sun Jan 01 00:00:00 EST 2023
Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF-κB signalling pathway.
Nephrology (Carlton, Vic.)
Liu Z,Xiang H,Deng Q,Fu W,Li Y,Yu Z,Qiu Y,Mei Z,Xu L
Thu Jun 01 00:00:00 EDT 2023
The rhythmic coupling of Egr-1 and Cidea regulates age-related metabolic dysfunction in the liver of male mice.
Nature communications
Wu J,Bu D,Wang H,Shen D,Chong D,Zhang T,Tao W,Zhao M,Zhao Y,Fang L,Li P,Xue B,Li CJ
Fri Mar 24 00:00:00 EDT 2023
ATG16L1 adopts a dual-binding site mode to interact with WIPI2b in autophagy.
Science advances
Gong X,Wang Y,Tang Y,Wang Y,Zhang M,Li M,Zhang Y,Pan L
Wed Mar 01 00:00:00 EST 2023
C9ORF72 suppresses JAK-STAT mediated inflammation.
iScience
Pang W,Hu F
Fri May 19 00:00:00 EDT 2023
Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation.
World journal of surgical oncology
Cheng X,Jia X,Wang C,Zhou S,Chen J,Chen L,Chen J
Tue Mar 28 00:00:00 EDT 2023
Reciprocal FGF19-GLI2 signaling induces epithelial-to-mesenchymal transition to promote lung squamous cell carcinoma metastasis.
Cellular oncology (Dordrecht)
Zhang Y,Wu T,Wang Y,Chen Z,Chen J,Lu S,Xia W
Sat Apr 01 00:00:00 EDT 2023
SARS-CoV-2 NSP7 inhibits type I and III IFN production by targeting the RIG-I/MDA5, TRIF, and STING signaling pathways.
Journal of medical virology
Deng J,Zheng Y,Zheng SN,Nan ML,Han L,Zhang J,Jin Y,Pan JA,Gao C,Wang PH
Wed Mar 01 00:00:00 EST 2023
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Developmental cell
Geng J,Khaket TP,Pan J,Li W,Zhang Y,Ping Y,Cobos Sillero MI,Lu B
Mon Apr 10 00:00:00 EDT 2023
BMF-AS1/BMF Promotes Diabetic Vascular Calcification and Aging both In Vitro and In Vivo.
Aging and disease
Lin X,Xiang QY,Li S,Song WL,Wang YJ,Ni YQ,Zhao Y,Li C,Wang Y,Li HH,Liang Z,Zhan JK,Liu YS
Wed Feb 01 00:00:00 EST 2023
Moderate-Intensity Treadmill Exercise Promotes mTOR-Dependent Motor Cortical Neurotrophic Factor Expression and Functional Recovery in a Murine Model of Crush Spinal Cord Injury (SCI).
Molecular neurobiology
Zhan Z,Pan L,Zhu Y,Wang Y,Zhao Q,Liu Y,Li S,Wang H,Yang C,Yu L,Yin Y,Tan B
Wed Feb 01 00:00:00 EST 2023
BPOZ-2 is a negative regulator of the NLPR3 inflammasome contributing to SARS-CoV-2-induced hyperinflammation.
Frontiers in cellular and infection microbiology
Li J,Lin H,Fan T,Huang L,Zhang X,Tai Y,Fang Y,Li Q,Zhao R,Wang P,Zhou L,Wan L,Wu Y,Zhong H,Wei C,Yang X
Mon Mar 27 00:00:00 EDT 2023
Barrier-penetrating liposome targeted delivery of basic fibroblast growth factor for spinal cord injury repair.
Materials today. Bio
Wu F,Wang P,Wei X,Yang Y,Al Mamun A,Zhang X,Zhu Y,Mo T,Zhang H,Jiang C,Hu J,Xiao J
Wed Feb 01 00:00:00 EST 2023
Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis.
Cell cycle (Georgetown, Tex.)
Qi D,Chen P,Bao H,Zhang L,Sun K,Song S,Li T
Sat Apr 01 00:00:00 EDT 2023
Discovery of alantolactone as a naturally occurring NLRP3 inhibitor to alleviate NLRP3-driven inflammatory diseases in mice.
British journal of pharmacology
Li W,Xu H,Shao J,Chen J,Lin Y,Zheng Z,Wang Y,Luo W,Liang G
Thu Jun 01 00:00:00 EDT 2023
Low expression of SEMA4D as a potential predictive molecular marker of poor survival in patients with melanoma combined with liver cancer.
Oncology letters
Liu X,Zhang C,Yang WH,Li SC,Wang RF,Zhang YB,Zhang ZL
Sat Apr 01 00:00:00 EDT 2023
The prognostic value of the GPAT/AGPAT gene family in hepatocellular carcinoma and its role in the tumor immune microenvironment.
Frontiers in immunology
Wen P,Wang R,Xing Y,Ouyang W,Yuan Y,Zhang S,Liu Y,Peng Z
Wed Mar 01 00:00:00 EST 2023
Porcine Epidemic Diarrhea Virus Replication in Human Intestinal Cells Reveals Potential Susceptibility to Cross-Species Infection.
Viruses
Niu Z,Zhang S,Xu S,Wang J,Wang S,Hu X,Zhang L,Ren L,Zhang J,Liu X,Zhou Y,Yang L,Song Z
Thu Apr 13 00:00:00 EDT 2023
Landscape of pathogenic mutations in premature ovarian insufficiency.
Nature medicine
Ke H,Tang S,Guo T,Hou D,Jiao X,Li S,Luo W,Xu B,Zhao S,Li G,Zhang X,Xu S,Wang L,Wu Y,Wang J,Zhang F,Qin Y,Jin L,Chen ZJ
Wed Feb 01 00:00:00 EST 2023
The Prognostic Value and the Oncogenic and Immunological Roles of Vacuolar Protein Sorting Associated Protein 26 A in Pancreatic Adenocarcinoma.
International journal of molecular sciences
Hou J,Wu H,Xu B,Shang J,Xu X,Li G,Zhang H,Zhang W,Deng Y,Hong X,Hu T,Zhang M,Zhan Y
Thu Feb 09 00:00:00 EST 2023
Sensitive and quantitative in vivo analysis of PD-L1 using magnetic particle imaging and imaging-guided immunotherapy.
European journal of nuclear medicine and molecular imaging
Peng Z,Lu C,Shi G,Yin L,Liang X,Song G,Tian J,Du Y
Sat Apr 01 00:00:00 EDT 2023
Extracellular acidosis restricts one-carbon metabolism and preserves T cell stemness.
Nature metabolism
Cheng H,Qiu Y,Xu Y,Chen L,Ma K,Tao M,Frankiw L,Yin H,Xie E,Pan X,Du J,Wang Z,Zhu W,Chen L,Zhang L,Li G
Wed Feb 01 00:00:00 EST 2023
Coupled deglycosylation-ubiquitination cascade in regulating PD-1 degradation by MDM2.
Cell reports
Wu Z,Cao Z,Yao H,Yan X,Xu W,Zhang M,Jiao Z,Zhang Z,Chen J,Liu Y,Zhang M,Wang D
Tue Jul 25 00:00:00 EDT 2023
Novel secreted STPKLRR from Vibrio splendidus AJ01 promotes pathogen internalization via mediating tropomodulin phosphorylation dependent cytoskeleton rearrangement.
PLoS pathogens
Dai F,Guo M,Shao Y,Li C
Mon May 01 00:00:00 EDT 2023
Schisandrin B induces HepG2 cells pyroptosis by activating NK cells mediated anti-tumor immunity.
Toxicology and applied pharmacology
Song A,Ding T,Wei N,Yang J,Ma M,Zheng S,Jin H
Tue Aug 01 00:00:00 EDT 2023
Subchronic Microcystin-LR Aggravates Colorectal Inflammatory Response and Barrier Disruption via Raf/ERK Signaling Pathway in Obese Mice.
Toxins
Yang Y,Zheng S,Chu H,Du C,Chen M,Emran MY,Chen J,Yang F,Tian L
Sat Apr 01 00:00:00 EDT 2023
P4HA2-mediated HIF-1α stabilization promotes erdafitinib-resistance in FGFR3-alteration bladder cancer.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li X,Li Y,Liu B,Chen L,Lyu F,Zhang P,He Q,Cheng L,Liu C,Song Y,Xing Y
Sat Apr 01 00:00:00 EDT 2023
Identification of biomarkers of hepatocellular carcinoma gene prognosis based on the immune-related lncRNA signature of transcriptome data.
Functional & integrative genomics
Ma A,Sun Y,Ogbodu RO,Xiao L,Deng H,Zhou H
Tue Mar 28 00:00:00 EDT 2023
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
European journal of medicinal chemistry
Lin H,Han H,Yang M,Wen Z,Chen Q,Ma Y,Wang X,Wang C,Yin T,Wang X,Lu G,Chen H,Qi J,Yang Y
Sun Mar 05 00:00:00 EST 2023
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
The journal of gene medicine
Yao B,Cai Y,Wan L,Deng J,Zhao L,Wang W,Han Z
Thu Jun 01 00:00:00 EDT 2023
Optimization of Primary Human Bronchial Epithelial 3D Cell Culture with Donor-Matched Fibroblasts and Comparison of Two Different Culture Media.
International journal of molecular sciences
Maurer J,Walles T,Wiese-Rischke C
Sat Feb 18 00:00:00 EST 2023
TMT proteomics analysis reveals the mechanism of bleomycin-induced pulmonary fibrosis and effects of Ginseng honeysuckle superfine powdered tea.
Chinese medicine
Li X,Yu X,Gao Y,Zhao W,Wang Y,Yu F,Fu C,Gao H,Cheng M,Li B
Wed May 24 00:00:00 EDT 2023
Hesperidin may improve depressive symptoms by binding NLRP3 and influencing the pyroptosis pathway in a rat model.
European journal of pharmacology
Cao H,Yang D,Nie K,Lin R,Peng L,Zhou X,Zhang M,Zeng Y,Liu L,Huang W
Sat Aug 05 00:00:00 EDT 2023
Comprehensive Analysis of NABP2 as a Prognostic Biomarker and Its Correlation with Immune Infiltration in Hepatocellular Carcinoma.
Journal of inflammation research
Li B,Liu J,Xu L,Xu Q,Liu Z,Liu T
Sun Apr 30 00:00:00 EDT 2023
Ant-Neointimal Formation Effects of SLC6A6 in Preventing Vascular Smooth Muscle Cell Proliferation and Migration via Wnt/β-Catenin Signaling.
International journal of molecular sciences
Rong Z,Li F,Zhang R,Niu S,Di X,Ni L,Liu C
Fri Feb 03 00:00:00 EST 2023
Methotrexate and Triptolide regulate Notch signaling pathway by targeting the Nedd4-Numb axis.
International immunopharmacology
Wu Q,Chen X,Qiao C,Cao X,Du Q,Yuan Y,Zuo Y,Miao Y,Zheng Z,Zhang T,Zang L,Yang X,Shi W,Xie Z,Xu Y,Wu D,Wen C,Zheng H
Sun Jan 01 00:00:00 EST 2023
Peroxiredoxin-6 Released by Astrocytes Contributes to Neuroapoptosis During Ischemia.
Neuroscience
Hou JY,Zhou XL,Wang XY,Liang J,Xue Q
Tue Feb 21 00:00:00 EST 2023
Combination effects of amino acid transporter LAT1 inhibitor nanvuranlat and cytotoxic anticancer drug gemcitabine on pancreatic and biliary tract cancer cells.
Cancer cell international
Nishikubo K,Ohgaki R,Liu X,Okanishi H,Xu M,Endou H,Kanai Y
Thu Jun 15 00:00:00 EDT 2023
Pinellia ternata lectin induces inflammation through TLR4 receptor and mediates PI3K/Akt/mTOR axis to regulate NF-κB signaling pathway.
Toxicology
Li J,Wang W,Yuan Y,Cui X,Bian H,Wen H,Zhang X,Yu H,Wu H
Wed Mar 01 00:00:00 EST 2023
Oncogenic roles of GPR176 in breast cancer: a potential marker of aggressiveness and a potential target of gene therapy.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Yun WJ,Xue H,Yang N,Xiao LJ,Sun HZ,Zheng HC
Sun Oct 01 00:00:00 EDT 2023
Bioengineered Bacteriophage-Like Nanoparticles as RNAi Therapeutics to Enhance Radiotherapy against Glioblastomas.
ACS nano
Pang HH,Huang CY,Chen PY,Li NS,Hsu YP,Wu JK,Fan HF,Wei KC,Yang HW
Tue Jun 13 00:00:00 EDT 2023
Heme oxygenase-1 protects against PM2.5 induced endothelial dysfunction through inhibition of HIF1α.
Environmental toxicology and pharmacology
Xu H,Wen Q,Xu X,Yu D,Liu Z,Zhang C,Zhang X,Ma J,Zhao H,Song L
Sun Jan 01 00:00:00 EST 2023
Human Umbilical Cord Mesenchymal Stem Cells Inhibit Pyroptosis of Renal Tubular Epithelial Cells through miR-342-3p/Caspase1 Signaling Pathway in Diabetic Nephropathy.
Stem cells international
Zheng S,Zhang K,Zhang Y,He J,Ouyang Y,Lang R,Ao C,Jiang Y,Xiao H,Li Y,Li M,Li C,Wu D
Sat Apr 15 00:00:00 EDT 2023
Novel insights into the mediating roles of cluster of differentiation 36 in transmembrane transport and tissue partition of per- and polyfluoroalkyl substances in mice.
Journal of hazardous materials
Jia Y,Zhu Y,Wang R,Ye Q,Xu D,Zhang W,Zhang Y,Shan G,Zhu L
Sun Jan 15 00:00:00 EST 2023
Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection.
Microbiology spectrum
Lin L,Yang J,Zhang D,Lv Q,Wang F,Liu P,Wang M,Shi C,Huang X,Liang W,Tan C,Wang X,Chen H,Wilson BA,Wu B,Peng Z
Tue Mar 14 00:00:00 EDT 2023
Identification and validation of hub genes in drug induced acute kidney injury basing on integrated transcriptomic analysis.
Frontiers in immunology
Deng YX,Liu K,Qiu QX,Tang ZY,Que RM,Li DK,Gu XR,Zhou GL,Wu YF,Zhou LY,Yin WJ,Zuo XC
Tue Apr 18 00:00:00 EDT 2023
Nanodrug rescues liver fibrosis via synergistic therapy with H2O2 depletion and Saikosaponin b1 sustained release.
Communications biology
Dong H,Han X,Hao M,Yang Q,Lyu Q,Tang D,Shen Z,Wang K,Kuang H,Cao G,Peng M,Shao M
Thu Feb 16 00:00:00 EST 2023
Ubiquitin-specific protease 24 promotes EV71 infection by restricting K63-linked polyubiquitination of TBK1.
Virologica Sinica
Zang L,Gu J,Yang X,Yuan Y,Guo H,Zhou W,Ma J,Chen Y,Wu Y,Zheng H,Shi W
Wed Feb 01 00:00:00 EST 2023
RUNX1/CD44 axis regulates the proliferation, migration, and immunotherapy of gliomas: A single-cell sequencing analysis.
Frontiers in immunology
Zhang H,Cao H,Luo H,Zhang N,Wang Z,Dai Z,Wu W,Liu G,Xie Z,Cheng Q,Cheng Y
Tue Feb 14 00:00:00 EST 2023
TUBA1C: a new potential target of LncRNA EGFR-AS1 promotes gastric cancer progression.
BMC cancer
Wang H,Cui H,Yang X,Peng L
Mon Mar 20 00:00:00 EDT 2023
Intermittent Fasting Alleviates Non-Alcoholic Steatohepatitis by Regulating Bile Acid Metabolism and Promoting Fecal Bile Acid Excretion in High-Fat and High-Cholesterol Diet Fed Mice.
Molecular nutrition & food research
Lin X,Zhu X,Xin Y,Zhang P,Xiao Y,He T,Guo H
Sat Jul 01 00:00:00 EDT 2023
DnaJC7 specifically regulates tau seeding.
bioRxiv : the preprint server for biology
Perez VA,Sanders DW,Mendoza-Oliva A,Stopschinski BE,Mullapudi V,White CL,Joachimiak LA,Diamond MI
Thu Mar 16 00:00:00 EDT 2023
An XBP1s-PIM-2 positive feedback loop controls IL-15-mediated survival of natural killer cells.
Science immunology
Ma S,Han J,Li Z,Xiao S,Zhang J,Yan J,Tang T,Barr T,Kraft AS,Caligiuri MA,Yu J
Fri Mar 17 00:00:00 EDT 2023
Tissue-resident CXCR4+ macrophage as a poor prognosis signature promotes pancreatic ductal adenocarcinoma progression.
International journal of cancer
Liao Z,Ye L,Li T,Jin X,Lin X,Fei Q,Zhang H,Shi S,Yu X,Jin K,Wu W
Thu Jun 01 00:00:00 EDT 2023
Hydroxysafflor yellow a confers neuroprotection against acute traumatic brain injury by modulating neuronal autophagy to inhibit NLRP3 inflammasomes.
Journal of ethnopharmacology
Lai Z,Li C,Ma H,Hua S,Liu Z,Huang S,Liu K,Li J,Feng Z,Cai Y,Zou Y,Tang Y,Jiang X
Tue May 23 00:00:00 EDT 2023
Cardiac-specific Trim44 knockout in rat attenuates isoproterenol-induced cardiac remodeling via inhibition of AKT/mTOR pathway.
Disease models & mechanisms
Jiang XY,Guan FF,Ma JX,Dong W,Qi XL,Zhang X,Chen W,Gao S,Gao X,Pan S,Wang JZ,Ma YW,Zhang LF,Lu D
Mon May 01 00:00:00 EDT 2023
Fetal factors disrupt placental and maternal iron homeostasis in murine β-thalassemia.
Blood
Yu Y,Woloshun RR,Lee JK,Ebea PO,Zhu S,Nemeth E,Garrick LM,Garrick MD,Collins JF
Thu Jul 13 00:00:00 EDT 2023
EphA2 is a functional entry receptor for HCMV infection of glioblastoma cells.
PLoS pathogens
Dong XD,Li Y,Li Y,Sun C,Liu SX,Duan H,Cui R,Zhong Q,Mou YG,Wen L,Yang B,Zeng MS,Luo MH,Zhang H
Mon May 01 00:00:00 EDT 2023
Combination therapy with ultrasound and 2D nanomaterials promotes recovery after spinal cord injury via Piezo1 downregulation.
Journal of nanobiotechnology
Zhang F,He X,Dong K,Yang L,Ma B,Liu Y,Liu Z,Chen B,Zhu R,Cheng L
Wed Mar 15 00:00:00 EDT 2023
ACC010, a novel BRD4 inhibitor, synergized with homoharringtonine in acute myeloid leukemia with FLT3-ITD.
Molecular oncology
Qian Y,Zhang X,Mao S,Wei W,Lin X,Ling Q,Ye W,Li F,Pan J,Zhou Y,Zhao Y,Huang X,Huang J,Tong H,Sun J,Jin J
Sat Jul 01 00:00:00 EDT 2023
Inhibition of tiRNA-Gly-GCC ameliorates neointimal formation via CBX3-mediated VSMCs phenotypic switching.
Frontiers in cardiovascular medicine
Rong Z,Li F,Zhang R,Niu S,Di X,Ni L,Liu C
Fri Feb 24 00:00:00 EST 2023
Oculocerebrorenal syndrome of Lowe (OCRL) controls leukemic T-cell survival by preventing excessive PI(4,5)P2 hydrolysis in the plasma membrane.
The Journal of biological chemistry
Chen H,Lu C,Tan Y,Weber-Boyvat M,Zheng J,Xu M,Xiao J,Liu S,Tang Z,Lai C,Li M,Olkkonen VM,Yan D,Zhong W
Thu Jun 01 00:00:00 EDT 2023
Hawthorn fruit extract protect against MC-LR-induced hepatotoxicity by attenuating oxidative stress and apoptosis.
Environmental toxicology
Wang Y,Guo Y,Liu H,Du X,Shi L,Wang W,Zhang S
Thu Jun 01 00:00:00 EDT 2023
Baicalin Ameliorates Lung Injury in Rats by Inhibiting NLRP3 Inflammasome Activation via NF-[Formula: see text]B Signaling Pathway.
The American journal of Chinese medicine
Yang X,Han J,Huan Z,Xu C,Wang Q,Ge X
Mon Jun 19 00:00:00 EDT 2023
Dendrobium mixture ameliorates type 2 diabetes mellitus with non-alcoholic fatty liver disease through PPAR gamma: An integrated study of bioinformatics analysis and experimental verification.
Frontiers in pharmacology
Zhuang S,Zhang J,Lin X,Wang X,Yu W,Shi H
Tue Mar 07 00:00:00 EST 2023
Silencing of FAM111B inhibits tumor growth and promotes apoptosis by decreasing AKT activity in ovarian cancer.
Experimental biology and medicine (Maywood, N.J.)
Wang W,Gu Y,Ni H,Quan Q,Guo L
Thu Jun 01 00:00:00 EDT 2023
Upregulation of PIK3IP1 monitors the anti-cancer activity of PI3Kα inhibitors in gastric cancer cells.
Biochemical pharmacology
Ma XB,Wang Y,Jia YJ,Liu YJ,Tian YQ,Liu Y,Hou GQ,Xu YC,Liu HM
Sun Jan 01 00:00:00 EST 2023
EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS.
Shock (Augusta, Ga.)
Deng M,He J,Hao C,Guo Y,Si H,Deng X,Zhang C,Li S,Yao S,Ren W,Yao W
Thu Jun 01 00:00:00 EDT 2023
Low-dose graphene oxide promotes tumor cells proliferation by activating PI3K-AKT-mTOR signaling via cellular membrane protein integrin αV.
Environmental pollution (Barking, Essex : 1987)
Zheng Z,Halifu A,Ma J,Liu L,Fu Q,Yi B,Du E,Tian D,Xu Y,Zhang Z,Zhu J
Tue Aug 01 00:00:00 EDT 2023
Dual role of PID1 in regulating apoptosis induced by distinct anticancer-agents through AKT/Raf-1-dependent pathway in hepatocellular carcinoma.
Cell death discovery
Yang J,Li S,He J,Xu Q,Xie M,Yang C,Wang H,Zhang Y,Wan Q,Xiang M
Fri Apr 28 00:00:00 EDT 2023
Amnion-derived serum amyloid A1 participates in sterile inflammation of fetal membranes at parturition.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Lin YK,Zhang F,Lei WJ,Gan XW,Li MD,Pan F,Wang WS,Sun K
Sat Apr 01 00:00:00 EDT 2023
Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway.
Cellular signalling
Hefni E,Menon D,Ma T,Asiedu EB,Sultan A,Meiller T,Schneider A,Sodhi A,Montaner S
Tue Aug 01 00:00:00 EDT 2023
mTOR inhibitor, gemcitabine and PD-L1 antibody blockade combination therapy suppresses pancreatic cancer progression via metabolic reprogramming and immune microenvironment remodeling in Trp53flox/+LSL-KrasG12D/+Pdx-1-Cre murine models.
Cancer letters
Qiu J,Feng M,Yang G,Cao Z,Liu Y,You L,Zhang T
Wed Feb 01 00:00:00 EST 2023
Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis.
Life science alliance
Wang TX,Duan KL,Huang ZX,Xue ZA,Liang JY,Dang Y,Zhang A,Xiong Y,Ding C,Guan KL,Yuan HX
Sun Jan 01 00:00:00 EST 2023
Exosomes from tannic acid-stimulated macrophages accelerate wound healing through miR-221-3p mediated fibroblasts migration by targeting CDKN1b.
International journal of biological macromolecules
Song X,Chen Y,Chen X,Zhao X,Zou Y,Li L,Zhou X,Li M,Zhang D,Ye G,Jia R,Yin Z
Mon Jul 31 00:00:00 EDT 2023
A terrified-sound stress causes cognitive impairment in female mice by impairing neuronal plasticity.
Brain research
Gao S,Zhang L,Wang X,Li R,Han L,Xiong X,Jiang Q,Cheng D,Xiao X,Li H,Yang J
Tue Aug 01 00:00:00 EDT 2023
Immunophenotyping of Monocyte Migration Markers and Therapeutic Effects of Selenium on IL-6 and IL-1β Cytokine Axes of Blood Mononuclear Cells in Preoperative and Postoperative Coronary Artery Disease Patients.
International journal of molecular sciences
Wacker M,Ball A,Beer HD,Schmitz I,Borucki K,Azizzadeh F,Scherner M,Awad G,Wippermann J,Veluswamy P
Thu Apr 13 00:00:00 EDT 2023
Perturbation of endoplasmic reticulum proteostasis triggers tissue injury in the thyroid gland.
JCI insight
Zhang X,Young C,Liao XH,Refetoff S,Torres M,Tomer Y,Stefan-Lifshitz M,Zhang H,Larkin D,Fang D,Qi L,Arvan P
Thu Jun 22 00:00:00 EDT 2023
FUT2-dependent fucosylation of HYOU1 protects intestinal stem cells against inflammatory injury by regulating unfolded protein response.
Redox biology
Wang Z,Tan C,Duan C,Wu J,Zhou D,Hou L,Qian W,Han C,Hou X
Sat Apr 01 00:00:00 EDT 2023
All-Trans Retinoic Acid-Responsive LGR6 Is Transiently Expressed during Myogenic Differentiation and Is Required for Myoblast Differentiation and Fusion.
International journal of molecular sciences
Kitakaze T,Tatsumi R,Yamaguchi M,Nakatsuji A,Harada N,Yamaji R
Sat May 20 00:00:00 EDT 2023
Targeting NAD metabolism regulates extracellular adenosine levels to improve the cytotoxicity of CD8+ effector T cells in the tumor microenvironment of gastric cancer.
Journal of cancer research and clinical oncology
Liu HY,Wang FH,Liang JM,Xiang YY,Liu SH,Zhang SW,Zhu CM,He YL,Zhang CH
Sat Jul 01 00:00:00 EDT 2023
Theabrownin Isolated from Pu-Erh Tea Enhances the Innate Immune and Anti-Inflammatory Effects of RAW264.7 Macrophages via the TLR2/4-Mediated Signaling Pathway.
Foods (Basel, Switzerland)
Zhao L,Miao Y,Shan B,Zhao C,Peng C,Gong J
Thu Mar 30 00:00:00 EDT 2023
MiR-29c Inhibits TNF-α-Induced ROS Production and Apoptosis in Mouse Hippocampal HT22 Cell Line.
Neurochemical research
Li B,Lu Y,Wang R,Xu T,Lei X,Jin H,Gao X,Xie Y,Liu X,Zeng J
Wed Feb 01 00:00:00 EST 2023
Heat shock factor 1 promotes neurite outgrowth and suppresses inflammation in the severed spinal cord of geckos.
Neural regeneration research
He BQ,Li AC,Hou YX,Li H,Zhang XY,Hao HF,Song HH,Cai RX,Wang YJ,Zhou Y,Wang YJ
Fri Sep 01 00:00:00 EDT 2023
Ginsenoside Rb1 improves energy metabolism after spinal cord injury.
Neural regeneration research
Wen S,Zou ZR,Cheng S,Guo H,Hu HS,Zeng FZ,Mei XF
Thu Jun 01 00:00:00 EDT 2023
Sex Differences in Genomic Features of Hepatitis B-Associated Hepatocellular Carcinoma With Distinct Antitumor Immunity.
Cellular and molecular gastroenterology and hepatology
Xu C,Cheng S,Chen K,Song Q,Liu C,Fan C,Zhang R,Zhu Q,Wu Z,Wang Y,Fan J,Zheng H,Lu L,Chen T,Zhao H,Jiao Y,Qu C
Thu Jan 26 00:00:00 EST 2023
Dysfunction of NRG1/ErbB4 Signaling in the Hippocampus Might Mediate Long-term Memory Decline After Systemic Inflammation.
Molecular neurobiology
Gao YZ,Wu XM,Zhou ZQ,Liu PM,Yang JJ,Ji MH
Thu Jun 01 00:00:00 EDT 2023
HDAC inhibitor chidamide overcomes drug resistance in chronic myeloid leukemia with the T315i mutation through the Akt-autophagy pathway.
Human cell
Yin L,Zhang Q,Xie S,Cheng Z,Li R,Zhu H,Yu Q,Yuan H,Wang C,Peng H,Zhang G
Sat Jul 01 00:00:00 EDT 2023
LIPUS accelerates bone regeneration via HDAC6-mediated ciliogenesis.
Biochemical and biophysical research communications
Xiao H,Yan A,Li M,Wang L,Xiang J
Sun Jan 22 00:00:00 EST 2023
Combinatorial expression of ebony and tan generates body color variation from nymph through adult stages in the cricket, Gryllus bimaculatus.
PloS one
Inoue S,Watanabe T,Hamaguchi T,Ishimaru Y,Miyawaki K,Nikawa T,Takahashi A,Noji S,Mito T
Mon May 22 00:00:00 EDT 2023
Pirfenidone suppressed triple-negative breast cancer metastasis by inhibiting the activity of the TGF-β/SMAD pathway.
Journal of cellular and molecular medicine
Luo D,Zeng X,Zhang S,Li D,Cheng Z,Wang Y,Long J,Hu Z,Long S,Zhou J,Zhang S,Zeng Z
Wed Feb 01 00:00:00 EST 2023
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.
Kidney international
Li J,Sun X,Yang N,Ni J,Xie H,Guo H,Wang X,Zhou L,Liu J,Chen S,Wang X,Zhang Y,Yu C,Zhang W,Lu L
Sun Jan 01 00:00:00 EST 2023
Xiaoyaosan ameliorates depressive-like behavior and susceptibility to glucose intolerance in rat: involvement of LepR-STAT3/PI3K pathway in hypothalamic arcuate nucleus.
BMC complementary medicine and therapies
Qiu W,Wu Q,Zhang K,Da X,Tang K,Yuan N,Deng L,Wu M,Zhang Y,Quan J,Ma Q,Li X,Chen J
Wed Apr 12 00:00:00 EDT 2023
Oncogenic FLT3 internal tandem duplication activates E2F1 to regulate purine metabolism in acute myeloid leukaemia.
Biochemical pharmacology
Ou ZY,Wang K,Shen WW,Deng G,Xu YY,Wang LF,Zai ZY,Ling YA,Zhang T,Peng XQ,Chen FH
Sat Apr 01 00:00:00 EDT 2023
Proteomic analysis reveals the mechanisms of the astaxanthin suppressed foam cell formation.
Life sciences
Liu A,Li R,Zaaboul F,He M,Li X,Shi J,Liu Y,Xu YJ
Sat Jul 15 00:00:00 EDT 2023
Epigenetically silenced lncRNA SNAI3-AS1 promotes ferroptosis in glioma via perturbing the m6A-dependent recognition of Nrf2 mRNA mediated by SND1.
Journal of experimental & clinical cancer research : CR
Zheng J,Zhang Q,Zhao Z,Qiu Y,Zhou Y,Wu Z,Jiang C,Wang X,Jiang X
Fri May 19 00:00:00 EDT 2023
Amyloid β oligomers disrupt piriform cortical output via a serotonergic pathway.
Neurobiology of aging
Wang X,Hu M,Xie Q,Geng C,Jin C,Ren W,Fan J,Ma T,Hu B
Sun Jan 01 00:00:00 EST 2023
All Domains of SARS-CoV-2 nsp1 Determine Translational Shutoff and Cytotoxicity of the Protein.
Journal of virology
Frolov I,Agback T,Palchevska O,Dominguez F,Lomzov A,Agback P,Frolova EI
Thu Mar 30 00:00:00 EDT 2023
JMJD8 regulates neuropathic pain by affecting spinal cord astrocyte differentiation.
Neuroscience letters
Li Y,Zhang Y,Zhou Z,Yi L,Ji F,Zhang K,Zhang Y,Xu H
Thu Jul 13 00:00:00 EDT 2023
Quantitative reactive cysteinome profiling reveals a functional link between ferroptosis and proteasome-mediated degradation.
Cell death and differentiation
Wang Y,Wang C
Sun Jan 01 00:00:00 EST 2023
Guanylate-binding protein 1 restricts avian coronavirus infectious bronchitis virus-infected HD11 cells.
Poultry science
Ma P,Gu K,Wen R,Li C,Zhou C,Zhao Y,Li H,Lei C,Yang X,Wang H
Wed Mar 01 00:00:00 EST 2023
Periplocin inhibits hepatocellular carcinoma progression and reduces the recruitment of MDSCs through AKT/NF-κB pathway.
Life sciences
Lin JP,Huang MH,Sun ZT,Chen L,Lei YH,Huang YQ,Qi M,Fan SR,Chen SG,Chung CW,Chan MC,Liu JS,Hu M,Chen MF,Ye WC,Chen YY,Deng LJ
Sat Jul 01 00:00:00 EDT 2023
Activating mitofusins interrupts mitochondrial degeneration and delays disease progression in SOD1 mutant amyotrophic lateral sclerosis.
Human molecular genetics
Dang X,Zhang L,Franco A,Dorn Ii GW
Mon Mar 20 00:00:00 EDT 2023
TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs.
Cell death & disease
Yang C,Jin X,Liu X,Wu G,Yang W,Pang B,Jiang J,Liao D,Zhang Y
Fri Jan 20 00:00:00 EST 2023
Phosphorylation and stabilization of EZH2 by DCAF1/VprBP trigger aberrant gene silencing in colon cancer.
Nature communications
Ghate NB,Kim S,Shin Y,Kim J,Doche M,Valena S,Situ A,Kim S,Rhie SK,Lenz HJ,Ulmer TS,Mumenthaler SM,An W
Mon Apr 17 00:00:00 EDT 2023
Antidepressant-like effect of CP-101,606: Evidence of mTOR pathway activation.
Molecular and cellular neurosciences
Qin Y,Guo X,Song W,Liang Z,Wang Y,Feng D,Yang Y,Li M,Gao M
Wed Mar 01 00:00:00 EST 2023
Exercise improves homeostasis of the intestinal epithelium by activation of apelin receptor-AMP-activated protein kinase signalling.
The Journal of physiology
Chae SA,Du M,Son JS,Zhu MJ
Thu Jun 01 00:00:00 EDT 2023
NSUN2-mediated M5c methylation of IRF3 mRNA negatively regulates type I interferon responses during various viral infections.
Emerging microbes & infections
Wang H,Feng J,Zeng C,Liu J,Fu Z,Wang D,Wang Y,Zhang L,Li J,Jiang A,He M,Cao Y,Yan K,Tang H,Guo D,Xu K,Zhou X,Zhou L,Lan K,Zhou Y,Chen Y
Fri Dec 01 00:00:00 EST 2023
Death-associated protein kinase 1 is associated with cognitive dysfunction in major depressive disorder.
Neural regeneration research
Li XH,Zhu HC,Cui XM,Wang W,Yang L,Wang LB,Hu NW,Duan DX
Tue Aug 01 00:00:00 EDT 2023
Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation.
iScience
Zhang C,Liu Z,Wang X,Zhang B,Cui L,Hu Q,Hu B,Cao K,Shan W,Shi H,Wang R
Fri Jun 16 00:00:00 EDT 2023
Targeting copper death genotyping associated gene RARRES2 suppresses glioblastoma progression and macrophages infiltration.
Cancer cell international
Yan T,Yang H,Meng Y,Li H,Jiang Q,Liu J,Xu C,Xue Y,Xu J,Song Y,Chu X,Wang L,Chen X,Che F
Mon May 29 00:00:00 EDT 2023
A novel cuproptosis-related gene signature to predict prognosis in Glioma.
BMC cancer
Zhang M,Liu X,Wang D,Ruan X,Wang P,Liu L,Xue Y
Mon Mar 13 00:00:00 EDT 2023
Direct administration of mesenchymal stem cell-derived mitochondria improves cardiac function after infarction via ameliorating endothelial senescence.
Bioengineering & translational medicine
Liang X,Zhang Y,Lin F,Li M,Li X,Chen Y,Liu J,Meng Q,Ma X,Wang E,Wei L,He Z,Fan H,Zhou X,Ding Y,Liu Z
Sun Jan 01 00:00:00 EST 2023
Direct administration of mesenchymal stem cell-derived mitochondria improves cardiac function after infarction via ameliorating endothelial senescence.
Bioengineering & translational medicine
Liang X,Zhang Y,Lin F,Li M,Li X,Chen Y,Liu J,Meng Q,Ma X,Wang E,Wei L,He Z,Fan H,Zhou X,Ding Y,Liu Z
Sun Jan 01 00:00:00 EST 2023
CircPVT1 promotes ER-positive breast tumorigenesis and drug resistance by targeting ESR1 and MAVS.
The EMBO journal
Yi J,Wang L,Hu GS,Zhang YY,Du J,Ding JC,Ji X,Shen HF,Huang HH,Ye F,Liu W
Mon May 15 00:00:00 EDT 2023
MiR-133a/CD47 axis is a novel prognostic biomarker to promote triple negative breast cancer progression.
Pathology, research and practice
Yan H,Huang W,Chen C,Zhang X,Zhu K,Yuan J
Sat Apr 01 00:00:00 EDT 2023
MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization.
EMBO reports
Zhang Y,Cao X,Gao Z,Ma X,Wang Q,Xu X,Cai X,Zhang Y,Zhang Z,Wei G,Wen B
Thu Aug 03 00:00:00 EDT 2023
Mitochondrial Glycerol-3-Phosphate Dehydrogenase Restricts HBV Replication via the TRIM28-Mediated Degradation of HBx.
Journal of virology
Liu C,Zhao K,Chen Y,Yao Y,Tang J,Wang J,Xu C,Yang Q,Zheng Y,Yuan Y,Sun H,Zhang Y,Zhou Y,Chen J,Wang Y,Wu C,Pei R,Chen X
Wed May 31 00:00:00 EDT 2023
Glioblastoma glycolytic signature predicts unfavorable prognosis, immunological heterogeneity, and ENO1 promotes microglia M2 polarization and cancer cell malignancy.
Cancer gene therapy
Liang X,Wang Z,Dai Z,Zhang H,Zhang J,Luo P,Liu Z,Liu Z,Yang K,Cheng Q,Zhang M
Wed Mar 01 00:00:00 EST 2023
Bone marrow mesenchymal stem cells repair hexavalent chromium-induced testicular injury by regulating autophagy and ferroptosis mediated by the AKT/mTOR pathway in rats.
Environmental toxicology
Zhuge R,Li Z,He C,Ma W,Yan J,Xue Q,Wang R,Liu Y,Lu R,Du H,Yin F,Guo L
Wed Feb 01 00:00:00 EST 2023
ROS Scavenging Nanozyme Modulates Immunosuppression for Sensitized Cancer Immunotherapy.
Advanced healthcare materials
Mo W,Liu S,Zhao X,Wei F,Li Y,Sheng X,Cao W,Ding M,Zhang W,Chen X,Meng L,Yao S,Diao W,Wei H,Guo H
Tue Aug 01 00:00:00 EDT 2023
Transcriptome analysis highlights the role of ferroptosis in palmitic acid-induced endothelial dysfunction.
Sexual medicine
Tan XH,Gu YY,Song WP,Nan TG,Song WD,Fang D,Yuan YM,Xin ZC,Li XS,Guan RL
Wed Feb 01 00:00:00 EST 2023
Macrophage migration inhibitory factor (MIF) inhibitor iSO-1 promotes staphylococcal protein A-induced osteogenic differentiation by inhibiting NF-κB signaling pathway.
International immunopharmacology
Shi X,Wu Y,Ni H,Li M,Qi B,Xu Y
Wed Feb 01 00:00:00 EST 2023
The Screening of Broadly Neutralizing Antibodies Targeting the SARS-CoV-2 Spike Protein by mRNA Immunization in Mice.
Pharmaceutics
An Z,Zhang Y,Yu X,Xia J,Yin Y,Li G,Lu J,Fan X,Xu Y
Fri May 05 00:00:00 EDT 2023
Menstrual blood-derived endometrial stem cells alleviate neuroinflammation by modulating M1/M2 polarization in cell and rat Parkinson's disease models.
Stem cell research & therapy
Li H,Wei J,Zhang Z,Li J,Ma Y,Zhang P,Lin J
Thu Apr 13 00:00:00 EDT 2023
VCAM-1+ hUC-MSCs Exert Considerable Neuroprotection Against Cerebral Infarction in Rats by Suppression of NLRP3-Induced Pyroptosis.
Neurochemical research
Zhang X,Sang X,Chen Y,Yu H,Sun Y,Liang X,Zheng X,Wang X,Yang H,Bi J,Zhang L,Wang P
Sun Oct 01 00:00:00 EDT 2023
Integrated network pharmacology and experimental verification to explore the molecular mechanism of Jingxin Zhidong formula for treating Tic disorder.
Journal of ethnopharmacology
Tian X,Ou G,Hu S,Wang C,Han F,Gao L
Thu Apr 06 00:00:00 EDT 2023
LncRNA WDR11-AS1 Promotes Extracellular Matrix Synthesis in Osteoarthritis by Directly Interacting with RNA-Binding Protein PABPC1 to Stabilize SOX9 Expression.
International journal of molecular sciences
Huang H,Yan J,Lan X,Guo Y,Sun M,Zhao Y,Zhang F,Sun J,Lu S
Tue Jan 03 00:00:00 EST 2023
Network pharmacology reveals that Berberine may function against Alzheimer's disease via the AKT signaling pathway.
Frontiers in neuroscience
Wei W,Yao JX,Zhang TT,Wen JY,Zhang Z,Luo YM,Cao Y,Li H
Tue May 23 00:00:00 EDT 2023
Lactiplantibacillus plantarum attenuates Coxsackievirus B3-induced pancreatitis through the BAX/BCL2/CASP3 signaling pathway.
Food & function
Yu X,Zhang Y,Pei K,Tan J,Tian H,Xu T,Liu F,Peng N,Huang Y,Huang X,Huang X,Wu J,Liu Q,Zeng L,Hua W,Huang X
Thu May 11 00:00:00 EDT 2023
Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine.
Cell
He K,Wan T,Wang D,Hu J,Zhou T,Tao W,Wei Z,Lu Q,Zhou R,Tian Z,Flavell RA,Zhu S
Thu Jul 06 00:00:00 EDT 2023
APOBEC3B coordinates R-loop to promote replication stress and sensitize cancer cells to ATR/Chk1 inhibitors.
Cell death & disease
Zong C,Zhang Z,Gao L,He J,Wang Y,Li Q,Liu X,Yang J,Chen D,Huang R,Zheng G,Jin X,Wei W,Jia R,Shen J
Sat Jun 03 00:00:00 EDT 2023
Embryonic Exposure to UV-328 Impairs the Cell Cycle in Zebrafish (Danio rerio) by Inhibiting the p38 MAPK/p53/Gadd45a Signaling Pathway.
Environmental science & technology
Zhang L,Shen L,Huang Y,Cui S,Zhao Q,Zhang C,Zhuang S,Jiang G
Tue Jul 11 00:00:00 EDT 2023
The therapeutic effect of tanshinone IIA in mouse astrocytes after treatment with Angiostrongylus cantonensis fifth-stage larval excretory-secretory products.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
Chen KY,Chen YJ,Cheng CJ,Jhan KY,Chiu CH,Wang LC
Tue Aug 01 00:00:00 EDT 2023
Glutaredoxin 1 protects lens epithelial cells from epithelial-mesenchymal transition by preventing casein kinase 1α S-glutathionylation during posterior capsular opacification.
Redox biology
Li C,Chen X,Zhang S,Liang C,Ma X,Zhang R,Yan H
Thu Jun 01 00:00:00 EDT 2023
c-kit+VEGFR-2+ Mesenchymal Stem Cells Differentiate into Cardiovascular Cells and Repair Infarcted Myocardium after Transplantation.
Stem cell reviews and reports
Zhou P,Yu SN,Zhang HF,Wang YL,Tao P,Tan YZ,Wang HJ
Sun Jan 01 00:00:00 EST 2023
FXR1 promotes proliferation, invasion and migration of hepatocellular carcinoma in vitro and in vivo.
Oncology letters
Zhao K,Gao J,Shi J,Shi C,Pang C,Li J,Guo W,Zhang S
Sun Jan 01 00:00:00 EST 2023
EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons.
The Journal of cell biology
Parker SS,Ly KT,Grant AD,Sweetland J,Wang AM,Parker JD,Roman MR,Saboda K,Roe DJ,Padi M,Wolgemuth CW,Langlais P,Mouneimne G
Mon May 01 00:00:00 EDT 2023
Proteome profiling of the prefrontal cortex of Fmr1 knockout mouse reveals enhancement of complement and coagulation cascades.
Journal of proteomics
Gao MM,Shi H,Yan HJ,Long YS
Wed Mar 15 00:00:00 EDT 2023
Hypoxia-Preconditioned Bone Marrow Mesenchymal Stem Cells Improved Cerebral Collateral Circulation and Stroke Outcome in Mice.
Arteriosclerosis, thrombosis, and vascular biology
Tian H,Yang X,Zhao J,Liu X,Liu X,Cai Y,Wehbe A,Ding Y,Yu S,Wei L,Liu L
Sat Jul 01 00:00:00 EDT 2023
Resistance to anti-HER2 therapy associated with the TSC2 nonsynonymous variant c.4349 C > G (p.Pro1450Arg) is reversed by CDK4/6 inhibitor in HER2-positive breast cancer.
NPJ breast cancer
Yang Z,Feng J,Jing J,Huang Y,Ye WW,Lei L,Wang XJ,Cao WM
Tue May 09 00:00:00 EDT 2023
CD137 signaling aggravates myocardial ischemia-reperfusion injury by inhibiting mitophagy mediated NLRP3 inflammasome activation.
Journal of geriatric cardiology : JGC
Zang GY,Yin Q,Shao C,Sun Z,Zhang LL,Xu Y,Li LH,Wang ZQ
Tue Mar 28 00:00:00 EDT 2023
Exosomal circCLIP1 regulates PM2.5-induced airway obstruction via targeting SEPT10 in vitro.
Ecotoxicology and environmental safety
Zhu H,Tang X,Zhang H,Zhou M,Liu H,Chu H,Zhang Z
Sat Apr 01 00:00:00 EDT 2023
Inositol polyphosphates-regulated polyubiquitination of PHR1 by NLA E3 ligase during phosphate starvation response in Arabidopsis.
The New phytologist
Park SH,Jeong JS,Huang CH,Park BS,Chua NH
Wed Feb 01 00:00:00 EST 2023
Methylthioacetic acid, a derivative of aroma compounds from Cucumis melo var. conomon dose-dependently triggers differentiation and apoptosis of RCM-1 human colorectal cancer cells.
The Journal of toxicological sciences
Kamimura M,Sasaki A,Otani Y,Nakamura Y,Nakamura T,Kuramochi K,Imai T,Kubo N,Okamoto S
Fri Jan 06 00:00:00 EST 2023
Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination.
Communications biology
Hu J,Jiang W,Zuo J,Shi D,Chen X,Yang X,Zhang W,Ma L,Liu Z,Xing Q
Tue Jan 17 00:00:00 EST 2023
CD27-Expressing Xenoantigen-Expanded Human Regulatory T Cells Are Efficient in Suppressing Xenogeneic Immune Response.
Cell transplantation
Cao L,Ma X,Zhang J,Yang M,He Z,Yang C,Li S,Rong P,Wang W
Wed Jan 18 00:00:00 EST 2023
Rhein Inhibited Ferroptosis and EMT to Attenuate Diabetic Nephropathy by Regulating the Rac1/NOX1/β-Catenin Axis.
Frontiers in bioscience (Landmark edition)
Xiong D,Hu W,Han X,Cai Y
Thu May 25 00:00:00 EDT 2023
MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.
iScience
Ji X,Chu L,Su D,Sun J,Song P,Sun S,Wang Y,Mu Q,Liu Y,Wan Q
Fri May 19 00:00:00 EDT 2023
Protective Effect of Lonicera japonica on PM2.5-Induced Pulmonary Damage in BALB/c Mice via the TGF-β and NF-κB Pathway.
Antioxidants (Basel, Switzerland)
Lee HL,Kim JM,Go MJ,Kim TY,Joo SG,Kim JH,Lee HS,Kim HJ,Heo HJ
Thu Apr 20 00:00:00 EDT 2023
Lenvatinib inhibited HCC cell migration and invasion through regulating the transcription and ubiquitination of UHRF1 and DNMT1.
Biochemical pharmacology
Fang T,Jiao Z,You Y,Cao J,Wang C,Liu J,Zhao W
Sat Apr 01 00:00:00 EDT 2023
Triptonide inhibits growth and metastasis in HCC by suppressing EGFR/PI3K/AKT signaling.
Neoplasma
Zhang H,Mao Y,Zou X,Niu J,Jiang J,Chen X,Zhu M,Yang X,Dong T
Wed Feb 01 00:00:00 EST 2023
Involvement of ferroptosis in Porphyromonas gingivalis lipopolysaccharide-stimulated periodontitis in vitro and in vivo.
Oral diseases
Qiao S,Li B,Cai Q,Li Z,Yin Z,He J,Li Y,Meng W
Wed Nov 01 00:00:00 EDT 2023
Betulinaldehyde exhibits effective anti-tumor effects in A549 cells by regulating intracellular autophagy.
Scientific reports
Huang PH,Duan XB,Tang ZZ,Zou ZX,Song WM,Gao G,Li D,Nie FQ,Yan X,Fu YX,Guo R,Xu YY
Fri Jan 13 00:00:00 EST 2023
Guilu-Erxian-Glue alleviates Tripterygium wilfordii polyglycoside-induced oligoasthenospermia in rats by resisting ferroptosis via the Keap1/Nrf2/GPX4 signaling pathway.
Pharmaceutical biology
Ding J,Lu B,Liu L,Zhong Z,Wang N,Li B,Sheng W,He Q
Fri Dec 01 00:00:00 EST 2023
C1q/tumor necrosis factor-related protein-9 exerts antioxidant and anti-inflammatory effects on oxygen-glucose deprivation/reoxygenation-stimulated neurons by modulating the Akt-GSK-3β-Nrf2 cascade via AdipoR1.
International immunopharmacology
Wang J,Ren B,Yang Y,Li Y
Mon May 01 00:00:00 EDT 2023
Activation of NLRP3 inflammasome in lung epithelial cells triggers radiation-induced lung injury.
Respiratory research
Rao X,Zhou D,Deng H,Chen Y,Wang J,Zhou X,Jie X,Xu Y,Wu Z,Wang G,Dong X,Zhang S,Meng R,Wu C,Xing S,Fan K,Wu G,Zhou R
Tue Jan 24 00:00:00 EST 2023
Xuanhuang Runtong Tablets Relieve Slow Transit Constipation in Mice by Regulating TLR5/IL-17A Signaling Mediated by Gut Microbes.
Evidence-based complementary and alternative medicine : eCAM
Liang X,Wan D,Cai Y,Yue W,Wang X,Zhou H,Zhou R,Du Q,Xiao J,Zhang S
Thu Feb 02 00:00:00 EST 2023
Mitochondrial decline in the ageing old world primate retina: Little evidence for difference between the centre and periphery.
PloS one
Kam JH,Shinhmar H,Powner MB,Hayes MJ,Aboelnour A,Jeffery G
Thu May 04 00:00:00 EDT 2023
LncRNA NR2F1-AS1 was involved in azacitidine resistance of THP-1 cells by targeting IGF1 with miR-483-3p.
Cytokine
Hu C,Li S,Fu X,Zhao X,Peng J
Wed Feb 01 00:00:00 EST 2023
Dietary choline metabolite TMAO impairs cognitive function and induces hippocampal synaptic plasticity declining through the mTOR/P70S6K/4EBP1 pathway.
Food & function
Zhou S,Liu J,Sun Y,Xu P,Liu JL,Sun S,Zhu B,Wu H
Mon Mar 20 00:00:00 EDT 2023
Staphylococcus aureus induces mitophagy to promote its survival within bovine mammary epithelial cells.
Veterinary microbiology
Xu D,Hu G,Luo J,Cheng J,Wu D,Cheng L,Huang X,Fu S,Liu J
Mon May 01 00:00:00 EDT 2023
Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis.
European journal of pharmacology
Zhang ML,Wang M,Chen J,Liu YJ,Yu YJ,Liu LM,Zheng XH,Xiao YC,Zhang JM,Zhu MX,Yue X,Zhao Y,Niu W,Li ZC
Sun Mar 05 00:00:00 EST 2023
Cerebrospinal fluid-derived extracellular vesicles after spinal cord injury promote vascular regeneration via PI3K/AKT signaling pathway.
Journal of orthopaedic translation
Li C,Qin T,Jin Y,Hu J,Yuan F,Cao Y,Duan C
Wed Mar 01 00:00:00 EST 2023
EPC-exosomal miR-26a-5p improves airway remodeling in COPD by inhibiting ferroptosis of bronchial epithelial cells via PTGS2/PGE2 signaling pathway.
Scientific reports
Liu C,Lu J,Yuan T,Xie L,Zhang L
Fri Apr 14 00:00:00 EDT 2023
An unconventional cancer-promoting function of methamphetamine in hepatocellular carcinoma.
Life science alliance
Si Z,Yang G,Wang X,Yu Z,Pang Q,Zhang S,Qian L,Ruan Y,Huang J,Yu L
Wed Mar 01 00:00:00 EST 2023
Themis suppresses the effector function of CD8+ T cells in acute viral infection.
Cellular & molecular immunology
Tang J,Jia X,Li J,Dong J,Wang J,Li W,Zhu Y,Hu Y,Hou B,Lin C,Cong Y,Ren T,Yan C,Yang H,Lai Q,Zheng H,Bao Y,Gautam N,Wang HR,Xu B,Chen XL,Li Q,Gascoigne NRJ,Fu G
Mon May 01 00:00:00 EDT 2023
Baicalein Suppresses NLRP3 and AIM2 Inflammasome-Mediated Pyroptosis in Macrophages Infected by Mycobacterium tuberculosis via Induced Autophagy.
Microbiology spectrum
Ning B,Shen J,Liu F,Zhang H,Jiang X
Thu Jun 15 00:00:00 EDT 2023
GATA zinc finger protein p66β promotes breast cancer cell migration by acting as a co-activator of Snail.
Cell death & disease
Zou X,Ma L,Zhang Y,Zhang Q,Xu C,Zhang D,Chu Y,Zhang J,Li M,Zhang H,Wang J,Peng C,Wei G,Wu Y,Hou Z,Jia H
Wed Jun 28 00:00:00 EDT 2023
Baicalin ameliorates multidrug-resistant Pseudomonas aeruginosa induced pulmonary inflammation in rat via arginine biosynthesis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li L,Cui H,Zhang Y,Xie W,Lin Y,Guo Y,Huang T,Xue B,Guo W,Huang Z,Man T,Yu H,Zhai Z,Cheng M,Wang M,Lei H,Wang C
Thu Jun 01 00:00:00 EDT 2023
Baicalin ameliorates multidrug-resistant Pseudomonas aeruginosa induced pulmonary inflammation in rat via arginine biosynthesis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Li L,Cui H,Zhang Y,Xie W,Lin Y,Guo Y,Huang T,Xue B,Guo W,Huang Z,Man T,Yu H,Zhai Z,Cheng M,Wang M,Lei H,Wang C
Thu Jun 01 00:00:00 EDT 2023
Photobiomodulation promotes spinal cord injury repair by inhibiting macrophage polarization through lncRNA TUG1-miR-1192/TLR3 axis.
Cellular & molecular biology letters
Ju C,Ma Y,Zuo X,Wang X,Song Z,Zhang Z,Zhu Z,Li X,Liang Z,Ding T,Hu X,Wang Z
Thu Jan 19 00:00:00 EST 2023
The E3 ligase RBCK1 reduces the sensitivity of ccRCC to sunitinib through the ANKRD35-MITD1-ANXA1 axis.
Oncogene
Wang Y,Peng M,Zhong Y,Xiong W,Zhu L,Jin X
Wed Mar 01 00:00:00 EST 2023
The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis.
Acta biochimica et biophysica Sinica
Li W,Tao C,Mao M,Zhu K
Fri May 26 00:00:00 EDT 2023
Acinous cell AR42J-derived exosome miR125b-5p promotes acute pancreatitis exacerbation by inhibiting M2 macrophage polarization via PI3K/AKT signaling pathway.
World journal of gastrointestinal surgery
Zheng Z,Cao F,Ding YX,Lu JD,Fu YQ,Liu L,Guo YL,Liu S,Sun HC,Cui YQ,Li F
Thu Apr 27 00:00:00 EDT 2023
PIWI-interacting RNA-17458 is oncogenic and a potential therapeutic target in cervical cancer.
Journal of Cancer
Liu L,Li L,Zu W,Jing J,Liu G,Sun T,Xie Q
Mon Jun 19 00:00:00 EDT 2023
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Zoological research
Zhang MF,Wan SC,Chen WB,Yang DH,Liu WQ,Li BL,Aierken A,Du XM,Li YX,Wu WP,Yang XC,Wei YD,Li N,Peng S,Li XL,Li GP,Hua JL
Thu May 18 00:00:00 EDT 2023
Ginsenoside Rg3 Ameliorates DSS-Induced Colitis by Inhibiting NLRP3 Inflammasome Activation and Regulating Microbial Homeostasis.
Journal of agricultural and food chemistry
Liu D,Tian Q,Liu K,Ren F,Liu G,Zhou J,Yuan L,Fang Z,Zou B,Wang S
Wed Feb 08 00:00:00 EST 2023
IL-33/ST2 axis promotes remodeling of the extracellular matrix and drives protective microglial responses in the mouse model of perioperative neurocognitive disorders.
International immunopharmacology
Li S,Liu H,Qian Y,Jiang L,Liu S,Liu Y,Liu C,Gu X
Sun Jan 01 00:00:00 EST 2023
ZY-444 inhibits the growth and metastasis of prostate cancer by targeting TNFAIP3 through TNF signaling pathway.
American journal of cancer research
Han MT,Pei H,Sun QQ,Wang CL,Li P,Xie YY,Cao LJ,Zhang XX,Sun ZL
Sun May 14 00:00:00 EDT 2023
The kinase inhibitory region of SOCS3 attenuates reactive astrogliosis and astroglial scar in mice after traumatic brain injury.
Journal of chemical neuroanatomy
Cai Z,Zhang Z,Zhang L,Tan R,Wang Y,Sun M,Hu X,Ge Q,An J,Lu H
Fri Sep 01 00:00:00 EDT 2023
ADAMTS12 promotes migration and epithelial-mesenchymal transition and predicts poor prognosis for pancreatic cancer.
Hepatobiliary & pancreatic diseases international : HBPD INT
He RZ,Zheng JH,Yao HF,Xu DP,Yang MW,Liu DJ,Sun YW,Huo YM
Sat Apr 01 00:00:00 EDT 2023
HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation.
Cellular & molecular immunology
Wang Z,Yan C,Du Q,Huang Y,Li X,Zeng D,Mao R,Gurram RK,Cheng S,Gu W,Zhu L,Fan W,Ma L,Ling Z,Qiu J,Li D,Liu E,Zhang Y,Fang Y,Zhu J,Sun B
Sat Apr 01 00:00:00 EDT 2023
CENP-I directly targets centromeric DNA to support CENP-A deposition and centromere maintenance.
Proceedings of the National Academy of Sciences of the United States of America
Hu L,Zhao C,Liu M,Liu S,Ye J,Wang K,Shi J,Tian W,He X
Tue Mar 14 00:00:00 EDT 2023
TIGD1 Function as a Potential Cuproptosis Regulator Following a Novel Cuproptosis-Related Gene Risk Signature in Colorectal Cancer.
Cancers
Wu Z,Lin C,Zhang F,Lu Z,Wang Y,Liu Y,Zhou Z,Li L,Song L
Thu Apr 13 00:00:00 EDT 2023
Disruption of the ADAM17/NF-κB feedback loop in astrocytes ameliorates HIV-1 Tat-induced inflammatory response and neuronal death.
Journal of neurovirology
Qiu X,Wang J,Zhang W,Duan C,Chen T,Zhang D,Su J,Gao L
Thu Jun 01 00:00:00 EDT 2023
CBL0137 activates ROS/BAX signaling to promote caspase-3/GSDME-dependent pyroptosis in ovarian cancer cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Yang C,Wang ZQ,Zhang ZC,Lou G,Jin WL
Mon May 01 00:00:00 EDT 2023
Mucin2 regulated by Ho1/p38/IL-10 axis plays a protective role in polystyrene nanoplastics-mediated intestinal toxicity.
Environmental pollution (Barking, Essex : 1987)
Cui M,He Q,Wang Z,Yu Y,Gao H,Liu Z,Peng H,Wang H,Zhang X,Li D,Chen L,Xing X,Xiao Y,Chen W,Wang Q
Tue Aug 01 00:00:00 EDT 2023
M6A-modified circRBM33 promotes prostate cancer progression via PDHA1-mediated mitochondrial respiration regulation and presents a potential target for ARSI therapy.
International journal of biological sciences
Zhong C,Long Z,Yang T,Wang S,Zhong W,Hu F,Teoh JY,Lu J,Mao X
Tue Apr 18 00:00:00 EDT 2023
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
International immunopharmacology
Teng S,Zhu Z,Wu C,He Y,Zhou S
Thu Jun 01 00:00:00 EDT 2023
Ectopic endometriotic stromal cells-derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis.
Immunology
Gou Y,Wang H,Wang T,Wang H,Wang B,Jiao N,Yu Y,Cao Y,Wang H,Zhang Z
Wed Mar 01 00:00:00 EST 2023
Effect of blood flow-restricted resistance training on myocardial fibrosis in early spontaneously hypertensive rats.
Frontiers in cardiovascular medicine
Tan Z,Chen P,Zheng Y,Pan Y,Wang B,Zhao Y
Fri Feb 24 00:00:00 EST 2023
Resveratrol Promotes Gluconeogenesis by Inhibiting SESN2-mTORC2-AKT Pathway in Calf Hepatocytes.
The Journal of nutrition
Wang G,Qin S,Geng H,Zheng Y,Li R,Xia C,Chen L,Yao J,Deng L
Sat Jul 01 00:00:00 EDT 2023
Bud31-mediated alternative splicing is required for spermatogonial stem cell self-renewal and differentiation.
Cell death and differentiation
Qin J,Huang T,Wang Z,Zhang X,Wang J,Dang Q,Cui D,Wang X,Zhai Y,Zhao L,Lu G,Shao C,Li S,Liu H,Liu Z
Sun Jan 01 00:00:00 EST 2023
Progerinin, an Inhibitor of Progerin, Alleviates Cardiac Abnormalities in a Model Mouse of Hutchinson-Gilford Progeria Syndrome.
Cells
Kang SM,Seo S,Song EJ,Kweon O,Jo AH,Park S,Woo TG,Kim BH,Oh GT,Park BJ
Mon Apr 24 00:00:00 EDT 2023
Toxicity of polystyrene nanoparticles for mouse ovary and cultured human granulosa cells.
Ecotoxicology and environmental safety
Huang J,Zou L,Bao M,Feng Q,Xia W,Zhu C
Sun Jan 01 00:00:00 EST 2023
1,8-Cineole ameliorates diabetic retinopathy by inhibiting retinal pigment epithelium ferroptosis via PPAR-γ/TXNIP pathways.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Z,Gan S,Fu L,Xu Y,Wang S,Zhang G,Pan D,Tao L,Shen X
Tue Aug 01 00:00:00 EDT 2023
N protein of PEDV plays chess game with host proteins by selective autophagy.
Autophagy
Zhai X,Kong N,Zhang Y,Song Y,Qin W,Yang X,Ye C,Ye M,Tong W,Liu C,Zheng H,Yu H,Zhang W,Yang X,Zhang G,Tong G,Shan T
Tue Aug 01 00:00:00 EDT 2023
Human Cytomegalovirus UL23 Antagonizes the Antiviral Effect of Interferon-γ by Restraining the Expression of Specific IFN-Stimulated Genes.
Viruses
Wang H,Peng W,Wang J,Zhang C,Zhao W,Ran Y,Yang X,Chen J,Li H
Thu Apr 20 00:00:00 EDT 2023
Kaempferol promotes melanogenesis and reduces oxidative stress in PIG1 normal human skin melanocytes.
Journal of cellular and molecular medicine
Xie Y,Mei X,Shi W
Sat Apr 01 00:00:00 EDT 2023
Triptolide injection reduces Alzheimer's disease-like pathology in mice.
Synapse (New York, N.Y.)
Mao R,Xu S,Sun G,Yu Y,Zuo Z,Wang Y,Yang K,Zhang Z,Yang W
Mon May 01 00:00:00 EDT 2023
Sestrin2 contributes to BRAF inhibitor resistance via reducing redox vulnerability of melanoma cells.
Journal of dermatological science
Guo S,Yue Q,Wang S,Wang H,Ye Z,Zhang W,Shi Q,Gao T,Li C,Zhu G
Wed Feb 01 00:00:00 EST 2023
Thioredoxin-1 regulates IRE1α to ameliorate sepsis-induced NLRP3 inflammasome activation and oxidative stress in Raw 264.7 cell.
Immunopharmacology and immunotoxicology
Shao R,Lou X,Xue J,Yang Y,Ning D,Chen G,Jiang L
Thu Jun 01 00:00:00 EDT 2023
The effect of PINK1/Parkin pathway on glucose homeostasis imbalance induced by tacrolimus in mouse livers.
Heliyon
Li Z,Xiang J,Mei S,Wu Y,Xu Y
Sat Apr 01 00:00:00 EDT 2023
PFC@O2 Targets HIF-1α to Reverse the Immunosuppressive TME in OSCC.
Journal of clinical medicine
Lan Z,Zou KL,Cui H,Chen H,Zhao YY,Yu GT
Tue Jan 10 00:00:00 EST 2023
Ferredoxin 1 regulates granulosa cell apoptosis and autophagy in polycystic ovary syndrome.
Clinical science (London, England : 1979)
Xing J,Qiao G,Luo X,Liu S,Chen S,Ye G,Zhang C,Yi J
Fri Mar 31 00:00:00 EDT 2023
Establishment of Risk Model and Analysis of Immunoinfiltration Based on Mitophagy-Related Associated Genes in Atrial Fibrillation.
Journal of inflammation research
Sang W,Wang L,Yan X,Sun H,Han Y,Wang F,Tang B,Li Y
Sat Jul 01 00:00:00 EDT 2023
HIF-1α Mediates Arsenic-Induced Metabolic Reprogramming in Lung Bronchial Epithelial Cells.
Biological trace element research
Wang W,Zhang A
Mon May 01 00:00:00 EDT 2023
Reduced hepatic bradykinin degradation accounts for cold-induced BAT thermogenesis and WAT browning in male mice.
Nature communications
Xiao F,Jiang H,Li Z,Jiang X,Chen S,Niu Y,Yin H,Shu Y,Peng B,Lu W,Li X,Li Z,Lan S,Xu X,Guo F
Tue May 02 00:00:00 EDT 2023
T-cell immunoglobulin- and mucin-domain-containing molecule-4 maintains adipose tissue homeostasis by orchestrating M2 macrophage polarization via nuclear factor kappa B pathway.
Immunology
Ding L,Liang Y,Wang Y,Tong Z,Liu W,Tan S,Zhang J,Wang Y,Wu Z,Liang X,Ma C,Gao L
Sun Jan 01 00:00:00 EST 2023
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.
Cellular and molecular gastroenterology and hepatology
Yuan J,Lv T,Yang J,Wu Z,Yan L,Yang J,Shi Y,Jiang L
Thu Jan 26 00:00:00 EST 2023
p53 protects against alcoholic fatty liver disease via ALDH2 inhibition.
The EMBO journal
Yao P,Zhang Z,Liu H,Jiang P,Li W,Du W
Mon Apr 17 00:00:00 EDT 2023
FBXO11 amplifies type I interferon signaling to exert antiviral effects by facilitating the assemble of TRAF3-TBK1-IRF3 complex.
Journal of medical virology
Gao L,Gao Y,Han K,Wang Z,Meng F,Liu J,Zhao X,Shao Y,Shen J,Sun W,Liu Y,Xu H,Du X,Li J,Qin FX
Wed Mar 01 00:00:00 EST 2023
ULK1-mediated metabolic reprogramming regulates Vps34 lipid kinase activity by its lactylation.
Science advances
Jia M,Yue X,Sun W,Zhou Q,Chang C,Gong W,Feng J,Li X,Zhan R,Mo K,Zhang L,Qian Y,Sun Y,Wang A,Zou Y,Chen W,Li Y,Huang L,Yang Y,Zhao Y,Cheng X
Fri Jun 02 00:00:00 EDT 2023
Gut microbiota from sigma-1 receptor knockout mice induces depression-like behaviors and modulates the cAMP/CREB/BDNF signaling pathway.
Frontiers in microbiology
Li JH,Liu JL,Li XW,Liu Y,Yang JZ,Chen LJ,Zhang KK,Xie XL,Wang Q
Tue Apr 25 00:00:00 EDT 2023
Segregation of pathways leading to pexophagy.
Life science alliance
Barone FG,Urbé S,Clague MJ
Mon May 01 00:00:00 EDT 2023
Effect of peroxiredoxin 1 on the regulation of trophoblast function by affecting autophagy and oxidative stress in preeclampsia.
Journal of assisted reproduction and genetics
Zhou M,Guo J,Li S,Li A,Fang Z,Zhao M,Zhang M,Wang X
Sat Jul 01 00:00:00 EDT 2023
Baicalin facilitates remyelination and suppresses neuroinflammation in rats with chronic cerebral hypoperfusion by activating Wnt/β-catenin and inhibiting NF-κB signaling.
Behavioural brain research
Xiao Y,Guan T,Yang X,Xu J,Zhang J,Qi Q,Teng Z,Dong Y,Gao Y,Li M,Meng N,Lv P
Tue Mar 28 00:00:00 EDT 2023
Charged multivesicular body protein 2B ameliorates biliary injury in the liver from donation after cardiac death rats via autophagy with air-oxygenated normothermic machine perfusion.
Biochimica et biophysica acta. Molecular basis of disease
Bai Y,Shi JH,Liu Q,Yang DJ,Yan ZP,Zhang JK,Tang HW,Guo WZ,Jin Y,Zhang SJ
Thu Jun 01 00:00:00 EDT 2023
Role of ionizing radiation activated NRF2 in lung cancer radioresistance.
International journal of biological macromolecules
Xu Q,Zhang P,Han X,Ren H,Yu W,Hao W,Luo B,Khan MI,Chen N
Fri Jun 30 00:00:00 EDT 2023
E2F1 inhibits cellular senescence and promotes oxaliplatin resistance in colorectal cancer.
Annals of translational medicine
Gao H,Zhou F,Li R,Yuan J,Ye L
Tue Feb 28 00:00:00 EST 2023
The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus.
Cell reports
Wen L,Yang X,Wu Z,Fu S,Zhan Y,Chen Z,Bi D,Shen Y
Tue Apr 25 00:00:00 EDT 2023
Downregulation of CBX7 induced by EZH2 upregulates FGFR3 expression to reduce sensitivity to cisplatin in bladder cancer.
British journal of cancer
Ren J,Yu H,Li W,Jin X,Yan B
Sun Jan 01 00:00:00 EST 2023
Selective HDAC6 inhibitor TubA offers neuroprotection after intracerebral hemorrhage via inhibiting neuronal apoptosis.
PeerJ
Peng C,Gong X,Hu Z,Chen C,Jiang Z
Fri May 19 00:00:00 EDT 2023
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages.
International immunopharmacology
Shen PC,Huang SH,Liu ZM,Lu CC,Chou SH,Tien YC
Sat Jul 01 00:00:00 EDT 2023
A biomaterial-based therapy using a sodium hyaluronate/bioglass composite hydrogel for the treatment of oral submucous fibrosis.
Acta biomaterialia
Guo ZX,Zhang Z,Yan JF,Xu HQ,Wang SY,Ye T,Han XX,Wang WR,Wang Y,Gao JL,Niu LN,Chang J,Jiao K
Wed Feb 01 00:00:00 EST 2023
Lin28a induced mitochondrial dysfunction in human granulosa cells via suppressing LARS2 expression.
Cellular signalling
Chen J,Liu W
Wed Mar 01 00:00:00 EST 2023
Molecular mechanisms in the miR-33a/LPPR4 pathway regulating unsaturated fatty acid synthesis in bovine mammary epithelial cells.
Animal biotechnology
Wu Y,Zhang W,Wang Y,Lu Q,Zhou J,Chen Z,Yang Z,Loor JJ
Fri Dec 01 00:00:00 EST 2023
Chromatin remodeler BRM is a key mediator of leucine-stimulated mTOR gene transcription in mouse mammary epithelial cells.
Biochemical and biophysical research communications
Ke C,Zhao S,Wang L,Zhang M,Gao X
Sun Feb 05 00:00:00 EST 2023
The U2AF65/circNCAPG/RREB1 feedback loop promotes malignant phenotypes of glioma stem cells through activating the TGF-β pathway.
Cell death & disease
Li H,Jiang Y,Hu J,Xu J,Chen L,Zhang G,Zhao J,Zong S,Guo Z,Li X,Zhao X,Jing Z
Fri Jan 13 00:00:00 EST 2023
Molecular weight-dependent hyaluronic acid permeability and tight junction modulation in human buccal TR146 cell monolayers.
International journal of biological macromolecules
Park HY,Kweon DK,Kim JK
Wed Feb 01 00:00:00 EST 2023
NSUN2-mediated m5 C RNA methylation dictates retinoblastoma progression through promoting PFAS mRNA stability and expression.
Clinical and translational medicine
Zuo S,Li L,Wen X,Gu X,Zhuang A,Li R,Ye F,Ge S,Fan X,Fan J,Chai P,Lu L
Mon May 01 00:00:00 EDT 2023
Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps.
Nature communications
Wang T,Zhou Y,Zhou Z,Zhang P,Yan R,Sun L,Ma W,Zhang T,Shen S,Liu H,Lu H,Ye L,Feng J,Chen Z,Zhong X,Wu G,Cai Y,Jia W,Gao P,Zhang H
Sat Mar 18 00:00:00 EDT 2023
Functional analysis of two SLC9A6 frameshift variants in lymphoblastoid cells from patients with Christianson syndrome.
CNS neuroscience & therapeutics
He H,Zhang H,Chen H,He F,Yin F,Stauber T,Zou X,Peng J
Fri Dec 01 00:00:00 EST 2023
Enterococcus faecalis promotes the progression of colorectal cancer via its metabolite: biliverdin.
Journal of translational medicine
Zhang L,Liu J,Deng M,Chen X,Jiang L,Zhang J,Tao L,Yu W,Qiu Y
Thu Feb 02 00:00:00 EST 2023
A core NRF2 gene set defined through comprehensive transcriptomic analysis predicts selective drug resistance and poor multi-cancer prognosis.
bioRxiv : the preprint server for biology
Luo G,Kumar H,Alridge K,Rieger S,Jiang E,Chan ER,Soliman A,Mahdi H,Letterio JJ
Thu Jun 29 00:00:00 EDT 2023
Holothuria leucospilota Polysaccharides Improve Immunity and the Gut Microbiota in Cyclophosphamide-Treated Immunosuppressed Mice.
Molecular nutrition & food research
Zhao F,Ma T,Zhang X,Zhao Q,Zhu K,Cao J,Liu Z,Shen X,Li C
Sat Apr 01 00:00:00 EDT 2023
Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.
Nature communications
Li L,Jiang D,Liu H,Guo C,Zhao R,Zhang Q,Xu C,Qin Z,Feng J,Liu Y,Wang H,Chen W,Zhang X,Li B,Bai L,Tian S,Tan S,Yu Z,Chen L,Huang J,Zhao JY,Hou Y,Ding C
Wed Mar 29 00:00:00 EDT 2023
SLC25A22 as a Key Mitochondrial Transporter Against Ferroptosis by Producing Glutathione and Monounsaturated Fatty Acids.
Antioxidants & redox signaling
Liu Y,Wang Y,Lin Z,Kang R,Tang D,Liu J
Sat Jul 01 00:00:00 EDT 2023
The outer mitochondrial membrane protein TMEM11 demarcates spatially restricted BNIP3/BNIP3L-mediated mitophagy.
The Journal of cell biology
Gok MO,Connor OM,Wang X,Menezes CJ,Llamas CB,Mishra P,Friedman JR
Mon Apr 03 00:00:00 EDT 2023
iTRAQ-based Proteomic Analysis Unveils ACSL4 as a Novel Potential Regulator of Human Endometrial Receptivity.
Endocrinology
Hu S,Sun Z,Li B,Zhao H,Wang Y,Yao G,Li X,Bian X,Li TC,Vankelecom H,Sun Y
Mon Jan 09 00:00:00 EST 2023
Transcription Factor BCL11A Regulates Schwann Cell Behavior During Peripheral Nerve Regeneration.
Molecular neurobiology
Zhang Y,Shen Y,Zhao L,Zhao Q,Zhao L,Yi S
Fri Sep 01 00:00:00 EDT 2023
The synbiotic mixture of lactulose and Bacillus coagulans protects intestinal barrier dysfunction and apoptosis in weaned piglets challenged with lipopolysaccharide.
Journal of animal science and biotechnology
Zheng W,Zhao Z,Yang Y,Ding L,Yao W
Sun Jun 11 00:00:00 EDT 2023
MLL4 Regulates the Progression of Non-Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis.
Cancer research and treatment
Yang Y,Qiu R,Weng Q,Xu Z,Song J,Zhao S,Meng M,Zhang D,Kong C,Wang H,Xu M,Zhao Z,Ji J
Sat Jul 01 00:00:00 EDT 2023
Phenylalanine diminishes M1 macrophage inflammation.
Science China. Life sciences
Zhang Q,Chen S,Guo Y,He F,Fu J,Ren W
Fri Dec 01 00:00:00 EST 2023
CMTM3 protects the gastric epithelial cells from apoptosis and promotes IL-8 by stabilizing NEMO during Helicobacter pylori infection.
Gut pathogens
Zhang J,Ning J,Fu W,Shi Y,Zhang J,Ding S
Mon Feb 13 00:00:00 EST 2023
A Physiologically Responsive Nanocomposite Hydrogel for Treatment of Head and Neck Squamous Cell Carcinoma via Proteolysis-Targeting Chimeras Enhanced Immunotherapy.
Advanced materials (Deerfield Beach, Fla.)
Wu Y,Chang X,Yang G,Chen L,Wu Q,Gao J,Tian R,Mu W,Gooding JJ,Chen X,Sun S
Wed Mar 01 00:00:00 EST 2023
Bisphenol P exposure in C57BL/6 mice caused gut microbiota dysbiosis and induced intestinal barrier disruption via LPS/TLR4/NF-κB signaling pathway.
Environment international
Ma N,Ma D,Liu X,Zhao L,Ma L,Ma D,Dong S
Mon May 01 00:00:00 EDT 2023
Alteration in branching morphogenesis via YAP/TAZ in fibroblasts of fetal lungs in an LPS-induced inflammation model.
Molecular medicine (Cambridge, Mass.)
Ko HS,Laiman V,Tsao PN,Chen CM,Chuang HC
Mon Jan 30 00:00:00 EST 2023
Remodeling of imbalanced extracellular matrix homeostasis for reversal of pancreatic fibrosis.
Biomaterials
Qi L,Han H,Han MM,Sun Y,Xing L,Jiang HL,Pandol SJ,Li L
Sun Jan 01 00:00:00 EST 2023
The Qi-Bang-Yi-Shen formula ameliorates renal dysfunction and fibrosis in rats with diabetic kidney disease via regulating PI3K/AKT, ERK and PPARγ signaling pathways.
European journal of histochemistry : EJH
Wang Z,Jian G,Chen T,Chen Y,Li J,Wang N
Wed Mar 01 00:00:00 EST 2023
The Effect of Gut Microbiota on the Progression of Intervertebral Disc Degeneration.
Orthopaedic surgery
Yao B,Cai Y,Wang W,Deng J,Zhao L,Han Z,Wan L
Wed Mar 01 00:00:00 EST 2023
Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Hu Y,Wen Q,Cai Y,Liu Y,Ma W,Li Q,Song F,Guo Y,Zhu L,Ge J,Zeng Q,Wang J,Yin C,Zheng G,Ge M
Sun Jan 01 00:00:00 EST 2023
CRISPR-Cas9-Mediated NPC1 Gene Deletion Enhances HEK 293 T Cell Adhesion by Regulating E-Cadherin.
Molecular biotechnology
Jia Z,Yang M,Zhao Y,Li X,Yang C,Qiao L,Li H,Du J,Lin J,Guan L
Wed Feb 01 00:00:00 EST 2023
An HPK1 inhibitor enhanced the tumour response to anti-PD-1 immunotherapy in non-Hodgkin's lymphoma.
Clinical and experimental medicine
Yang L,Zhao Q,Chen T,Liu W,Qiu X,Chen J,Huang S,Huang R,Dong L
Wed Nov 01 00:00:00 EDT 2023
Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration.
Cell reports
Sun L,Zhang X,Wu S,Liu Y,Guerrero-Juarez CF,Liu W,Huang J,Yao Q,Yin M,Li J,Ramos R,Liao Y,Wu R,Xia T,Zhang X,Yang Y,Li F,Heng S,Zhang W,Yang M,Tzeng CM,Ji C,Plikus MV,Gallo RL,Zhang LJ
Tue Jun 27 00:00:00 EDT 2023
BAP31 regulates the expression of ICAM-1/VCAM-1 via MyD88/NF-κB pathway in acute lung injury mice model.
Life sciences
Li G,Jiang X,Liang X,Hou Y,Zang J,Zhu B,Jia C,Niu K,Liu X,Xu X,Jiang R,Wang B
Sun Jan 15 00:00:00 EST 2023
Cul5 mediates taurine-stimulated mTOR mRNA expression and proliferation of mouse mammary epithelial cells.
Amino acids
Xu M,Zhou Y,Fan S,Zhang M,Gao X
Wed Feb 01 00:00:00 EST 2023
Combination of hyperlipidemia and 17β-Estradiol induces TMJOA-like pathological changes in rats.
Oral diseases
Zhao Y,Gan YH
Wed Nov 01 00:00:00 EDT 2023
LncRNA LINC00534 regulates cell proliferation and migration via the miR-494-3p/PTEN axis in HTR-8/SVneo cells.
Journal of clinical laboratory analysis
Song X,Zhang X,Xia Q,Li C,Zhang Y,Huang Y,Meng L,Wang C,Li J,Long W
Sun Jan 01 00:00:00 EST 2023
Moderate Intensity of Treadmill Exercise Rescues TBI-Induced Ferroptosis, Neurodegeneration, and Cognitive Impairments via Suppressing STING Pathway.
Molecular neurobiology
Chen J,Zhu T,Yu D,Yan B,Zhang Y,Jin J,Yang Z,Zhang B,Hao X,Chen Z,Yan C,Yu J
Fri Sep 01 00:00:00 EDT 2023
Prognosis-related VDAC1 regulates the proliferation and apoptosis of osteosarcoma cells via the MAPK signaling pathway.
Genomics
Cai X,Zhu S
Mon May 01 00:00:00 EDT 2023
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Inflammation
Shen Y,Teng L,Qu Y,Huang Y,Peng Y,Tang M,Fu Q
Sat Apr 01 00:00:00 EDT 2023
rTMS treatment for abrogating intracerebral hemorrhage-induced brain parenchymal metabolite clearance dysfunction in male mice by regulating intracranial lymphatic drainage.
Brain and behavior
Liu Y,Liu X,Sun P,Li J,Nie M,Gong J,He A,Zhao M,Yang C,Wang Z
Sat Jul 01 00:00:00 EDT 2023
GSTP1-mediated S-glutathionylation of Pik3r1 is a redox hub that inhibits osteoclastogenesis through regulating autophagic flux.
Redox biology
Ji X,Hong J,Yang W,Yao M,Wang J,Jiang G,Wang Y,Li C,Lin J,Mou H,Li C,Li S,Chen Y,Shi M,Wang W,Lu F,Wu H,Zhao X,Qi Y,Yan S
Mon May 01 00:00:00 EDT 2023
Forced activation of dystrophin transcription by CRISPR/dCas9 reduced arrhythmia susceptibility via restoring membrane Nav1.5 distribution.
Gene therapy
Zhang R,Liu J,Xue G,Yang J,Li D,Tian T,Zhang X,Gao K,Pan Z
Wed Feb 01 00:00:00 EST 2023
Discovery of a natural small-molecule AMP-activated kinase activator that alleviates nonalcoholic steatohepatitis.
Marine life science & technology
Chen J,Xu L,Zhang XQ,Liu X,Zhang ZX,Zhu QM,Liu JY,Iqbal MO,Ding N,Shao CL,Wei MY,Gu YC
Mon May 01 00:00:00 EDT 2023
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma.
Nature metabolism
Yang Z,Yan C,Ma J,Peng P,Ren X,Cai S,Shen X,Wu Y,Zhang S,Wang X,Qiu S,Zhou J,Fan J,Huang H,Gao Q
Sun Jan 01 00:00:00 EST 2023
High-frequency repetitive transcranial magnetic stimulation protects against cerebral ischemia/reperfusion injury in rats: Involving the mitigation of ferroptosis and inflammation.
Brain and behavior
Zhou GJ,Liu DN,Huang XR,Wu Q,Feng WB,Zeng YH,Liu HY,Yu J,Xiao ZJ,Zhou J
Mon May 01 00:00:00 EDT 2023
Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion.
The Journal of pharmacy and pharmacology
Zhang X,Yang X,Zhang S,Wang J,Wang M,Ma T,Wan M,Lv X,Yan T,Jia Y
Fri Apr 07 00:00:00 EDT 2023
Integrating HPLC-Q-TOF-MS/MS, network pharmacology and experimental validation to decipher the chemical substances and mechanism of modified Gui-shao-liu-jun-zi decoction against gastric cancer.
Journal of traditional and complementary medicine
Huang W,Wen F,Ruan S,Gu P,Gu S,Song S,Zhou J,Li Y,Liu J,Shu P
Mon May 01 00:00:00 EDT 2023
Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit.
Journal of molecular biology
Kozai D,Numoto N,Nishikawa K,Kamegawa A,Kawasaki S,Hiroaki Y,Irie K,Oshima A,Hanzawa H,Shimada K,Kitano Y,Fujiyoshi Y
Mon May 15 00:00:00 EDT 2023
mGluR5 in hippocampal CA1 pyramidal neurons mediates stress-induced anxiety-like behavior.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Li X,Du ZJ,Xu JN,Liang ZM,Lin S,Chen H,Li SJ,Li XW,Yang JM,Gao TM
Sat Jul 01 00:00:00 EDT 2023
Advanced glycation end products promote the progression of chronic kidney diseases by targeting calpain 6.
Amino acids
Zhang Y,Han H,Qian Y,Wang Q,Jiang M
Sat Jul 01 00:00:00 EDT 2023
Membrane-dependent actin polymerization mediated by the Legionella pneumophila effector protein MavH.
bioRxiv : the preprint server for biology
Zhang Q,Wan M,Mao Y
Tue Jan 24 00:00:00 EST 2023
Myristic acid as a checkpoint to regulate STING-dependent autophagy and interferon responses by promoting N-myristoylation.
Nature communications
Jia M,Wang Y,Wang J,Qin D,Wang M,Chai L,Fu Y,Zhao C,Gao C,Jia J,Zhao W
Tue Feb 07 00:00:00 EST 2023
SIM imaging resolves endocytosis of SARS-CoV-2 spike RBD in living cells.
Cell chemical biology
Miao L,Yan C,Chen Y,Zhou W,Zhou X,Qiao Q,Xu Z
Thu Mar 16 00:00:00 EDT 2023
Canagliflozin ameliorates the development of NAFLD by preventing NLRP3-mediated pyroptosis through FGF21-ERK1/2 pathway.
Hepatology communications
Huang S,Wu B,He Y,Qiu R,Yang T,Wang S,Lei Y,Li H,Zheng F
Wed Mar 01 00:00:00 EST 2023
STAT3/Mitophagy Axis Coordinates Macrophage NLRP3 Inflammasome Activation and Inflammatory Bone Loss.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Zhu L,Wang Z,Sun X,Yu J,Li T,Zhao H,Ji Y,Peng B,Du M
Wed Feb 01 00:00:00 EST 2023
IFIT2 Depletion Promotes Cancer Stem Cell-like Phenotypes in Oral Cancer.
Biomedicines
Lai KC,Regmi P,Liu CJ,Lo JF,Lee TC
Tue Mar 14 00:00:00 EDT 2023
African swine fever virus pA104R protein acts as a suppressor of type I interferon signaling.
Frontiers in microbiology
Chen Q,Li L,Guo S,Liu Z,Liu L,Tan C,Chen H,Wang X
Tue Apr 25 00:00:00 EDT 2023
Inhibition of cGAS ameliorates acute lung injury triggered by zinc oxide nanoparticles.
Toxicology letters
Jiang Z,Jiang Y,Fan J,Zhang J,Xu G,Fan Y,Zhang L,Qin X,Jiang X,Mao L,Liu G,Chen C,Zou Z
Sun Jan 15 00:00:00 EST 2023
Donkey Oil-Based Ketogenic Diet Prevents Tumor Progression by Regulating Intratumor Inflammation, Metastasis and Angiogenesis in CT26 Tumor-Bearing Mice.
Genes
Zhang H,Xie L,Zhang N,Qi X,Lu T,Xing J,Akhtar MF,Li L,Liu G
Sun Apr 30 00:00:00 EDT 2023
Sirtuin 1 activator alleviated lethal inflammatory injury via promotion of autophagic degradation of pyruvate kinase M2.
Frontiers in pharmacology
Zhao S,Sun Y,Wu X,Yang Y,Fan K,Hu K,Qin Y,Li K,Lin L,Chen K,Ma Y,Zhu M,Liu G,Zhang L
Fri Apr 28 00:00:00 EDT 2023
Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6.
iScience
Ding L,Zhang Y,Wang Y,Wang Y,Tong Z,Li P,Chen C,Wang B,Yue X,Li C,Wu Z,Liang X,Ma C,Gao L
Fri Jun 16 00:00:00 EDT 2023
QiHuangYiShen Granules Modulate the Expression of LncRNA MALAT1 and Attenuate Epithelial-Mesenchymal Transition in Kidney of Diabetic Nephropathy Rats.
Evidence-based complementary and alternative medicine : eCAM
Yuan LS,Du H,Ren QY,Yang RL,Liu SW,Liu SY,Shi KF,Wang B,Meng XF,Li TX,Zhang N
Sat Feb 11 00:00:00 EST 2023
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Wu J,Li J,Wu Y,Yang M,Chen Y,Wang N,Wang J,Yuan Z,Yi J,Yang C
Sat Jul 01 00:00:00 EDT 2023
Pterostilbene Confers Protection against Diquat-Induced Intestinal Damage with Potential Regulation of Redox Status and Ferroptosis in Broiler Chickens.
Oxidative medicine and cellular longevity
Chen Y,Zhang H,Li Y,Wang T
Mon Feb 06 00:00:00 EST 2023
Cofilin promotes tau pathology in Alzheimer's disease.
Cell reports
Yan M,Tang L,Dai L,Lei C,Xiong M,Zhang X,He M,Tian Y,Xiong J,Ke W,Zhang Z,Zhang C,Deng X,Zhang Z
Tue Feb 28 00:00:00 EST 2023
Evaluation of different rat models intrauterine adhesion models and improvement of the technique for their establishment.
Experimental animals
Xi J,Pan Y,Jin C,Liu J,Cheng J,Xu B
Wed May 17 00:00:00 EDT 2023
Hydroxysafflor Yellow A Exerts Neuroprotective Effect by Reducing Aβ Toxicity Through Inhibiting Endoplasmic Reticulum Stress in Oxygen-Glucose Deprivation/Reperfusion Cell Model.
Rejuvenation research
Ma HH,Wen JR,Fang H,Su S,Wan C,Zhang C,Lu FM,Fan LL,Wu GL,Zhou ZY,Qiao LJ,Zhang SJ,Cai YF
Sat Apr 01 00:00:00 EDT 2023
Disorders in the gut and liver are involved in depression contagion between isosexual post-stroke depression mice and the healthy cohabitors.
Behavioural brain research
Wang H,Pan MB,Jiang ST,Wang YC,Zhu Y,Zhang QC,Dong YF
Wed Feb 15 00:00:00 EST 2023
Interaction of Nmi and IFP35 Promotes Mutual Protein Stabilization and IRF3 and IRF7 Degradation to Suppress Type I IFN Production in Teleost Fish.
Journal of immunology (Baltimore, Md. : 1950)
Li L,Chen SN,Wang KL,Li N,Pang AN,Liu LH,Li B,Hou J,Wang S,Nie P
Mon May 15 00:00:00 EDT 2023
The stromal-tumor amplifying STC1-Notch1 feedforward signal promotes the stemness of hepatocellular carcinoma.
Journal of translational medicine
Bai S,Zhao Y,Chen W,Peng W,Wang Y,Xiong S,Li Y,Yang Y,Chen S,Cheng B,Wang R
Fri Mar 31 00:00:00 EDT 2023
CDGSH iron sulfur domain 2 over-expression alleviates neuronal ferroptosis and brain injury by inhibiting lipid peroxidation via AKT/mTOR pathway following intracerebral hemorrhage in mice.
Journal of neurochemistry
Li R,Zhang X,Gu L,Yuan Y,Luo X,Shen W,Xie Z
Mon May 01 00:00:00 EDT 2023
Effects and mechanisms of Xiaochaihu Tang against liver fibrosis: An integration of network pharmacology, molecular docking and experimental validation.
Journal of ethnopharmacology
Wang SJ,Ye W,Li WY,Tian W,Zhang M,Sun Y,Feng YD,Liu CX,Liu SY,Cao W,Meng JR,Li XQ
Wed Mar 01 00:00:00 EST 2023
Thiram-induced hyperglycemia causes tibial dyschondroplasia by triggering aberrant ECM remodeling via the gut-pancreas axis in broiler chickens.
Journal of hazardous materials
Mo Q,Kulyar MF,Quan C,Ding Y,Zhang Y,Zhang L,Pan H,Li J
Wed Feb 15 00:00:00 EST 2023
Ketogenic Diet Combined with Moderate Aerobic Exercise Training Ameliorates White Adipose Tissue Mass, Serum Biomarkers, and Hepatic Lipid Metabolism in High-Fat Diet-Induced Obese Mice.
Nutrients
Yan J,Ren C,Dong Y,Wali JA,Song H,Zhang Y,Zhang H,Kou G,Raubenheimer D,Cui Z
Tue Jan 03 00:00:00 EST 2023
Gomphrena globosa L. extract alleviates carbon tetrachoride-induced liver injury in mice by activating antioxidant signaling pathways and promoting autophagy.
Molecular biology reports
Wei Y,Tan W,Qin H,Jin M,Yu H,Cheng J,Feng H
Sun Jan 01 00:00:00 EST 2023
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
Journal of ethnopharmacology
Fu S,Song X,Tang X,Qian X,Du Z,Hu Y,Xu X,Zhang M
Mon Apr 24 00:00:00 EDT 2023
Synergistic effects of L-theanine and epigallocatechin gallate in alleviating ovalbumin allergy by regulating intestinal immunity through inhibition of mast cell degranulation.
Food & function
Xu W,Song X,Qu Q,Gong Z,Xiao W
Tue Feb 21 00:00:00 EST 2023
Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1.
Autophagy
Liu Y,Zhang H,Liu Y,Zhang S,Su P,Wang L,Li Y,Liang Y,Wang X,Zhao W,Chen B,Luo D,Zhang N,Yang Q
Fri Sep 01 00:00:00 EDT 2023
RNF20 is required for male fertility through regulation of H2B ubiquitination in the Sertoli cells.
Cell & bioscience
Lai F,Wang H,Zhao X,Yang K,Cai L,Hu M,Lin L,Xia X,Li W,Cheng H,Zhou R
Thu Apr 06 00:00:00 EDT 2023
Reshaping the Endogenous Electric Field to Boost Wound Repair via Electrogenerative Dressing.
Advanced materials (Deerfield Beach, Fla.)
Luo R,Liang Y,Yang J,Feng H,Chen Y,Jiang X,Zhang Z,Liu J,Bai Y,Xue J,Chao S,Xi Y,Liu X,Wang E,Luo D,Li Z,Zhang J
Sat Apr 01 00:00:00 EDT 2023
ZDHHC2-Mediated AGK Palmitoylation Activates AKT-mTOR Signaling to Reduce Sunitinib Sensitivity in Renal Cell Carcinoma.
Cancer research
Sun Y,Zhu L,Liu P,Zhang H,Guo F,Jin X
Thu Jun 15 00:00:00 EDT 2023
Effects of Caprylic Acid and Eicosapentaenoic Acid on Lipids, Inflammatory Levels, and the JAK2/STAT3 Pathway in ABCA1-Deficient Mice and ABCA1 Knock-Down RAW264.7 Cells.
Nutrients
Zhang X,Zhang P,Liu Y,Liu Z,Xu Q,Zhang Y,Liu L,Yang X,Li L,Xue C
Mon Mar 06 00:00:00 EST 2023
Lymphocyte-Related Immunomodulatory Therapy with Siponimod (BAF-312) Improves Outcomes in Mice with Acute Intracerebral Hemorrhage.
Aging and disease
Zhang Z,Li Y,Shi J,Zhu L,Dai Y,Fu P,Liu S,Hong M,Zhang J,Wang J,Jiang C
Thu Jun 01 00:00:00 EDT 2023
Apelin-13 Improves Cognitive Impairment and Repairs Hippocampal Neuronal Damage by Activating PGC-1α/PPARγ Signaling.
Neurochemical research
Chen B,Wu J,Hu S,Liu Q,Yang H,You Y
Mon May 01 00:00:00 EDT 2023
Overexpression of hepatic pescadillo 1 in obesity induces lipid dysregulation by inhibiting autophagy.
Translational research : the journal of laboratory and clinical medicine
Zhou J,Lu Y,Lin Y,Li C,Liu J,Jiang Z,Chen K
Tue Aug 01 00:00:00 EDT 2023
Hyperbaric oxygen enhanced the chemotherapy of mitochondrial targeting molecule IR-780 in bladder cancer.
Journal of cancer research and clinical oncology
Shen C,Yue X,Dai L,Wang J,Li J,Fang Q,Zhi Y,Shi C,Li W
Wed Feb 01 00:00:00 EST 2023
Luteolin improves vasoconstriction function and survival of septic mice via AMPK/NF-κB pathway.
Heliyon
Liu B,Su H
Wed Feb 01 00:00:00 EST 2023
Cyanidin-3-O-glucoside and protocatechuic acid alleviate heat stress-induced testicular damage.
Food & function
Cai D,Li X,Xu Q,Li H,Liu R,Chen J,Jiang X,Sun J,Lai C,Bai W
Tue Feb 21 00:00:00 EST 2023
Adipocyte YTH N(6)-methyladenosine RNA-binding protein 1 protects against obesity by promoting white adipose tissue beiging in male mice.
Nature communications
Yan S,Zhou X,Wu C,Gao Y,Qian Y,Hou J,Xie R,Han B,Chen Z,Wei S,Gao X
Mon Mar 13 00:00:00 EDT 2023
Flavonoids dimers from the fruits of Psoralea corylifolia and their cytotoxicity against MCF-7 cells.
Bioorganic chemistry
Xu QX,Wang ZJ,He ZC,Xu J,Xu W,Yang XW
Sun Jan 01 00:00:00 EST 2023
Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET.
Toxicology and applied pharmacology
Qi Y,Hu M,Qiu Y,Zhang L,Yan Y,Feng Y,Feng C,Hou X,Wang Z,Zhang D,Zhao J
Sat Apr 15 00:00:00 EDT 2023
Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice.
Aging
Peng S,Yu Y,Li J,Jiang D,Xu G,Wu L,Hu J
Fri Mar 17 00:00:00 EDT 2023
Dioscin reduced chemoresistance for colon cancer and analysis of sensitizing targets.
Biochemical and biophysical research communications
Li R,Qin J,Wang Z,Lv F,Guo J,Zhu H,Huang Y
Sun Jan 01 00:00:00 EST 2023
Genetic lineage tracing reveals stellate cells as contributors to myofibroblasts in pancreas and islet fibrosis.
iScience
Wang J,Li T,Zhou Y,Wang X,Carvalho V,Ni C,Li W,Wang Q,Chen Y,Shang Z,Qiu S,Sun Z
Fri Jun 16 00:00:00 EDT 2023
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
BMC molecular and cell biology
Chen J,Lei C,Zhang H,Huang X,Yang Y,Liu J,Jia Y,Shi H,Zhang Y,Zhang J,Du J
Fri Mar 03 00:00:00 EST 2023
STK24 Promotes Progression of LUAD and Modulates the Immune Microenvironment.
Mediators of inflammation
Li Y,Liu Y,Wang K,Xue D,Huang Y,Tan Z,Chen Y
Tue May 16 00:00:00 EDT 2023
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats.
Frontiers in pharmacology
Ma P,Huang N,Tang J,Zhou Z,Xu J,Chen Y,Zhang M,Huang Q,Cheng Y
Sat Mar 04 00:00:00 EST 2023
Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.
Journal of ethnopharmacology
Zhang Y,Wang S,Dai X,Liu T,Liu Y,Shi H,Yin J,Xu T,Zhang Y,Zhao D,Sukhorukov V,Orekhov AN,Gao S,Wang L,Zhang D
Thu Aug 10 00:00:00 EDT 2023
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
Journal of orthopaedic translation
Chen D,Jiang X,Zou H
Wed Mar 01 00:00:00 EST 2023
Baicalin Reduces Immune Cell Infiltration by Inhibiting Inflammation and Protecting Tight Junctions in Ischemic Stroke Injury.
The American journal of Chinese medicine
Hao Z,Zhang Z,Zhao Y,Wang D
Fri Mar 31 00:00:00 EDT 2023
Targeting ACYP1-mediated glycolysis reverses lenvatinib resistance and restricts hepatocellular carcinoma progression.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Wang S,Zhou L,Ji N,Sun C,Sun L,Sun J,Du Y,Zhang N,Li Y,Liu W,Lu W
Sat Jul 01 00:00:00 EDT 2023
Clinical Implications of a New DDX58 Pathogenic Variant That Causes Lupus Nephritis due to RIG-I Hyperactivation.
Journal of the American Society of Nephrology : JASN
Peng J,Wang Y,Han X,Zhang C,Chen X,Jin Y,Yang Z,An Y,Zhang J,Liu Z,Chen Y,Gao E,Zhang Y,Xu F,Zheng C,Zhou Q,Liu Z
Wed Feb 01 00:00:00 EST 2023
Anti-Neuroinflammatory Meroterpenoids from a Chinese Collection of the Brown Alga Sargassum siliquastrum.
Journal of natural products
Qi Y,Wang Z,Zhang J,Tang S,Zhu H,Jiang B,Li X,Wang J,Sun Z,Zhao M,Zhu H,Yan P
Fri May 26 00:00:00 EDT 2023
Escherichia coli enhances Th17/Treg imbalance via TLR4/NF-κB signaling pathway in oral lichen planus.
International immunopharmacology
Wang J,Yang J,Xia W,Zhang M,Tang H,Wang K,Zhou C,Qian L,Fan Y
Thu Jun 01 00:00:00 EDT 2023
TRPM8 promotes hepatocellular carcinoma progression by inducing SNORA55 mediated nuclear-mitochondrial communication.
Cancer gene therapy
Fu J,Liu G,Zhang X,Lei X,Liu Q,Qian K,Tong Q,Qin W,Li Z,Cao Z,Zhang J,Liu C,Wang Z,Liu Z,Liang XM,Yamamoto H,Xu X
Mon May 01 00:00:00 EDT 2023
Absorbable suture knots on the supraspinatus tendon prevent adverse effects of nonabsorbable suture knots in a rat model.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
Ben H,Luo C,Cheng J,Zeng CH,Zhou Y,Jeon IH,Sun Y
Sat Jul 01 00:00:00 EDT 2023
Lysine crotonylation of SERCA2a correlates to cardiac dysfunction and arrhythmia in Sirt1 cardiac-specific knockout mice.
International journal of biological macromolecules
Chen HX,Wang XC,Hou HT,Wang J,Yang Q,Chen YL,Chen HZ,He GW
Sat Jul 01 00:00:00 EDT 2023
RIG-I Promotes Tumorigenesis and Confers Radioresistance of Esophageal Squamous Cell Carcinoma by Regulating DUSP6.
International journal of molecular sciences
Li L,Lv L,Xu JC,He Q,Chang N,Cui YY,Tao ZC,Zhu T,Qian LT
Wed Mar 15 00:00:00 EDT 2023
Emodin attenuates inflammation and demyelination in experimental autoimmune encephalomyelitis.
Neural regeneration research
Cui YR,Bu ZQ,Yu HY,Yan LL,Feng J
Sat Jul 01 00:00:00 EDT 2023
Knockdown of PKMYT1 is associated with autophagy inhibition and apoptosis induction and suppresses tumor progression in hepatocellular carcinoma.
Biochemical and biophysical research communications
Wu F,Tu C,Zhang K,Che H,Lin Q,Li Z,Zhou Q,Tang B,Yang Y,Chen M,Shao C
Sun Jan 15 00:00:00 EST 2023
RBM10 Loss Promotes EGFR-Driven Lung Cancer and Confers Sensitivity to Spliceosome Inhibition.
Cancer research
Bao Y,Zhang S,Zhang X,Pan Y,Yan Y,Wang N,Ren Y,Zuo J,Zong WX,Wang Z,Wang Y
Tue May 02 00:00:00 EDT 2023
Acinetobacter baumannii outer membrane protein A induces autophagy in bone marrow-derived dendritic cells involving the PI3K/mTOR pathway.
Immunity, inflammation and disease
Tan H,Cao L
Sat Apr 01 00:00:00 EDT 2023
PGAM4 silencing inhibited glycolysis and chemoresistance to temozolomide in glioma cells.
Cell biology international
Lu B,Nie XH,Yin R,Ding P,Su ZZ,Qiu S,Qian YF
Sat Apr 01 00:00:00 EDT 2023
Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner.
Cellular oncology (Dordrecht)
Huang S,Zhang NQ,Xu CJ,Huang WQ,Li DX,Li J,Yao LL,Sundquist K,Sundquist J,Jiang SH,Xing X,Hu LP,Zhang ZG,Ji J,Zhang XL
Tue Aug 01 00:00:00 EDT 2023
Network Pharmacology-Based Identification of Key Targets of Ziyin Mingmu Pills Acting on Age-Related Macular Degeneration.
Evidence-based complementary and alternative medicine : eCAM
Yang Y,Wang Y,Liu X,Deng Y,Lu J,Jiang F,Nie F,Peng J,Peng Q,Qin Y
Tue Feb 14 00:00:00 EST 2023
Anti-oxidative-initiated cognitive impairment amelioration in Alzheimer's disease model rats through preventive transcutaneous electrical acupoint stimulation.
Integrative medicine research
Weng H,Wang Q,Ye R,Bai Y,Yang H,Xu G,Wang Q
Thu Jun 01 00:00:00 EDT 2023
A Genome-Wide Association Study for Susceptibility to Axial Length in Highly Myopic Eyes.
Phenomics (Cham, Switzerland)
Lu Q,Du Y,Zhang Y,Chen Y,Li H,He W,Tang Y,Zhao Z,Zhang Y,Wu J,Zhu X,Lu Y
Thu Jun 01 00:00:00 EDT 2023
Loss of exosomal miR-200b-3p from hypoxia cancer-associated fibroblasts promotes tumorigenesis and reduces sensitivity to 5-Flourouracil in colorectal cancer via upregulation of ZEB1 and E2F3.
Cancer gene therapy
Gong W,Guo Y,Yuan H,Chai R,Wan Z,Zheng B,Hu X,Chen B,Gao S,Dai Q,Yu P,Tu S
Thu Jun 01 00:00:00 EDT 2023
The cytotoxicity of zinc oxide nanoparticles to 3D brain organoids results from excessive intracellular zinc ions and defective autophagy.
Cell biology and toxicology
Liu L,Wang J,Zhang J,Huang C,Yang Z,Cao Y
Wed Feb 01 00:00:00 EST 2023
Effects of substrate topography on the regulation of human fibroblasts and capsule formation via modulating macrophage polarization.
Colloids and surfaces. B, Biointerfaces
Chen C,Chen Y,Lan YJ,Tian MN,Zhang YM,Lei ZY,Fan DL
Wed Feb 01 00:00:00 EST 2023
A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases.
Theranostics
Tao G,Liu F,Jin Z,Liu B,Wang H,Li D,Tang W,Chen Y,He Q,Qin S
Wed May 24 00:00:00 EDT 2023
Identification and functional analysis of three novel genetic variants resulting in premature termination codons in three unrelated patients with hereditary antithrombin deficiency.
International journal of hematology
Imai Y,Nagaya S,Araiso Y,Meguro-Horike M,Togashi T,Ohmori K,Makita Y,Sato E,Yujiri T,Nagamori Y,Horike SI,Watanabe A,Morishita E
Sat Apr 01 00:00:00 EDT 2023
Aqueous-soluble components of sporoderm-removed Ganoderma lucidum spore powder promote ferroptosis in oral squamous cell carcinoma.
Chinese journal of cancer research = Chung-kuo yen cheng yen chiu
Wu X,Wu Q,Wang Y,Liu Y,Li Z,Liu Q,Huang Z,Li M,Zhang B,Zhan Q
Sun Apr 30 00:00:00 EDT 2023
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy.
Molecular therapy : the journal of the American Society of Gene Therapy
Liu JL,Zhang L,Huang Y,Li XH,Liu YF,Zhang SM,Zhao YE,Chen XJ,Liu Y,He LY,Dong Z,Liu FY,Sun L,Xiao L
Wed May 03 00:00:00 EDT 2023
Vacuole Membrane Protein 1 (VMP1) Restricts NLRP3 Inflammasome Activation by Modulating SERCA Activity and Autophagy.
Research square
Zack SR,Nikolaienko R,Cook B,Melki R,Zima AV,Campbell EM
Fri Jan 27 00:00:00 EST 2023
NPTX2 Promotes Epithelial-Mesenchymal Transition in Cutaneous Squamous Cell Carcinoma through METTL3-Mediated N6-Methyladenosine Methylation of SNAIL.
The Journal of investigative dermatology
Kang T,Zhang C,Lei H,Luo R,Liu M,Wang S,Zhang X,Duan Q,Xiao S,Zheng Y
Thu Jun 01 00:00:00 EDT 2023
Circular RNA METTL9 contributes to neuroinflammation following traumatic brain injury by complexing with astrocytic SND1.
Journal of neuroinflammation
Huang C,Sun L,Xiao C,You W,Sun L,Wang S,Zhang Z,Liu S
Fri Feb 17 00:00:00 EST 2023
TIPE1 promotes liver regeneration by enhancing ROS-FoxO1 axis mediated autophagy.
The FEBS journal
Zhang X,Li S,Ren X,Xiang P,Zhang Y,Wang T,Qin Q,Sun F,Liu J,Gao L,Ma C,Yue X,Yang X,Han S,Liang X
Wed Feb 01 00:00:00 EST 2023
Apolipoprotein A4 Elevates Sympathetic Activity and Thermogenesis in Male Mice.
Nutrients
Kuo HN,LaRussa Z,Xu FM,West K,Consitt L,Davidson WS,Liu M,Coschigano KT,Shi H,Lo CC
Fri May 26 00:00:00 EDT 2023
Caffeine can alleviate non-alcoholic fatty liver disease by augmenting LDLR expression via targeting EGFR.
Food & function
Huang YW,Wang LT,Zhang M,Nie Y,Yang JB,Meng WL,Wang XJ,Sheng J
Mon Apr 03 00:00:00 EDT 2023
MAVS-Based Reporter Systems for Real-Time Imaging of EV71 Infection and Antiviral Testing.
Viruses
Li X,Yang E,Li X,Fan T,Guo S,Yang H,Wu B,Wang H
Wed Apr 26 00:00:00 EDT 2023
Identification of hub genes and pathways in lung metastatic colorectal cancer.
BMC cancer
Dai W,Guo C,Wang Y,Li Y,Xie R,Wu J,Yao B,Xie D,He L,Li Y,Huang H,Wang Y,Liu S
Thu Apr 06 00:00:00 EDT 2023
Lipid phosphatase SAC1 suppresses hepatitis B virus replication through promoting autophagic degradation of virions.
Antiviral research
Zheng J,Deng Y,Wei Z,Zou H,Wen X,Cai J,Zhang S,Jia B,Lu M,Lu K,Lin Y
Mon May 01 00:00:00 EDT 2023
Rs15285, a functional polymorphism located in lipoprotein lipase, predicts the risk and prognosis of gastric cancer.
Applied microbiology and biotechnology
Shen K,Zhou X,Hu L,Xiao J,Cheng Q,Wang Y,Liu K,Fan H,Xu Z,Yang L
Mon May 01 00:00:00 EDT 2023
TMEM2 induces epithelial-mesenchymal transition and promotes resistance to temozolomide in GBM cells.
Heliyon
Gao L,Tong S,Liu J,Cai J,Ye Z,Zhou L,Song P,Li Z,Lei P,Wei H,Hua Q,Tian D,Cai Q
Thu Jun 01 00:00:00 EDT 2023
Perilla frutescens L. alleviates trimethylamine N-oxide-induced apoptosis in the renal tubule by regulating ASK1-JNK phosphorylation.
Phytotherapy research : PTR
Yong C,Huang G,Ge H,Zhu Y,Yang Y,Yu Y,Tian F,Gao K,Zhou E
Sat Apr 01 00:00:00 EDT 2023
miR-100-5p Regulates Skeletal Muscle Myogenesis through the Trib2/mTOR/S6K Signaling Pathway.
International journal of molecular sciences
Wang K,Liufu S,Yu Z,Xu X,Ai N,Li X,Liu X,Chen B,Zhang Y,Ma H,Yin Y
Wed May 17 00:00:00 EDT 2023
COLEC10 Induces Endoplasmic Reticulum Stress by Occupying GRP78 and Inhibits Hepatocellular Carcinoma.
Laboratory investigation; a journal of technical methods and pathology
Cai MN,Chen DM,Xiao LX,Li SS,Liao CH,Li J,Huang ZX,Wang JL,Gu YR,Gu L,Huang YH,Lian YF
Sat Jul 01 00:00:00 EDT 2023
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
EMBO molecular medicine
Southwell N,Primiano G,Nadkarni V,Attarwala N,Beattie E,Miller D,Alam S,Liparulo I,Shurubor YI,Valentino ML,Carelli V,Servidei S,Gross SS,Manfredi G,Chen Q,D'Aurelio M
Mon Jul 10 00:00:00 EDT 2023
PKM2 allosteric converter: A self-assembly peptide for suppressing renal cell carcinoma and sensitizing chemotherapy.
Biomaterials
Wang L,Fu B,Hou DY,Lv YL,Yang G,Li C,Shen JC,Kong B,Zheng LB,Qiu Y,Wang HL,Liu C,Zhang JJ,Bai SY,Li LL,Wang H,Xu WH
Mon May 01 00:00:00 EDT 2023
Notch mediates the glycolytic switch via PI3K/Akt signaling to support embryonic development.
Cellular & molecular biology letters
Wang H,Liang W,Wang X,Zhan Y,Wang W,Yang L,Zhu Y
Mon Jun 26 00:00:00 EDT 2023
A Disintegrin and Metalloproteinase 10 (ADAM10) Is Essential for Oligodendrocyte Precursor Development and Myelination in the Mouse Brain.
Molecular neurobiology
Guo D,Huang F,Xue R,Ma Y,Xiao L,Lou H,Pan S
Wed Mar 01 00:00:00 EST 2023
EGFR-TNFR1 pathway in endothelial cell facilitates acute lung injury by NF-κB/MAPK-mediated inflammation and RIP3-dependent necroptosis.
International immunopharmacology
Zhang H,Zhang X,Ling C,Liu C,Hua S,Xiong Z,Zhao H,Feng Q,Feng Z,Tang J,Hong X
Sat Apr 01 00:00:00 EDT 2023
Influence of cyclin D1 splicing variants expression on breast cancer chemoresistance via CDK4/CyclinD1-pRB-E2F1 pathway.
Journal of cellular and molecular medicine
Wang J,Zhang J,Ma Q,Zhang S,Ma F,Su W,Zhang T,Xie X,Di C
Sat Apr 01 00:00:00 EDT 2023
Interleukin-1 increases cyclooxygenase-2 expression and prostaglandin E2 production in human granulosa-lutein cell via nuclear factor kappa B/P65 and extracellular signal-regulated kinase 1/2 signaling pathways.
Molecular and cellular endocrinology
Wan S,Chen Q,Xiang Y,Sang Y,Tang M,Song Y,Feng G,Ye B,Bai L,Zhu Y
Mon May 01 00:00:00 EDT 2023
Adiponectin Attenuates Splenectomy-Induced Cognitive Deficits by Neuroinflammation and Oxidative Stress via TLR4/MyD88/NF-κb Signaling Pathway in Aged Rats.
ACS chemical neuroscience
Zhang Z,Guo L,Yang F,Peng S,Wang D,Lai X,Su B,Xie H
Wed May 17 00:00:00 EDT 2023
Tanshinone IIA analogue 15a inhibits NLRP3-mediated inflammation by activating mitophagy in macrophages to alleviate acute tubular necrosis.
International immunopharmacology
Chen J,Luo W,Hu C,Ren M,Xu H,Xu X,Li W,Chen Y,Shao J,Xiao Z,Lv X,Liang G
Mon May 01 00:00:00 EDT 2023
Osmoadaptive GLP-1R signalling in hypothalamic neurones inhibits antidiuretic hormone synthesis and release.
Molecular metabolism
Greenwood MP,Greenwood M,Bárez-López S,Hawkins JW,Short K,Tatovic D,Murphy D
Sat Apr 01 00:00:00 EDT 2023
miR-124-3p improves mitochondrial function of renal tubular epithelial cells in db/db mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liang L,Wo C,Yuan Y,Cao H,Tan W,Zhou X,Wang D,Chen R,Shi M,Zhang F,Xiao Y,Liu L,Zhou Y,Zhang T,Wang Y,Guo B
Wed Mar 01 00:00:00 EST 2023
Role of Berberine Thermosensitive Hydrogel in Periodontitis via PI3K/AKT Pathway In Vitro.
International journal of molecular sciences
Wang C,Liu C,Liang C,Qu X,Zou X,Du S,Zhang Q,Wang L
Tue Mar 28 00:00:00 EDT 2023
FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system.
Cell death and differentiation
Zhu Y,Zhang H,Mao H,Zhong S,Huang Y,Chen S,Yan K,Zhao Z,Hao X,Zhang Y,Yao H,Huang X,Wang M,Zhang W,Li J,Meng G,Qin X,Ye Z,Shen J,Song Y,Xu Y,Yang Z,Wang L,Zhang Y,Wen L
Sun Jan 01 00:00:00 EST 2023
PKMYT1 inhibits lung adenocarcinoma progression by abrogating AKT1 activity.
Cellular oncology (Dordrecht)
Wang S,Liu X,Zhou T,Li J,Lin Y,Zhou A,Huang J,Zhao J,Cai J,Cai X,Huang Y,Li X
Wed Feb 01 00:00:00 EST 2023
Paeoniflorin-6'-O-benzene sulfonate protected the intestinal epithelial barrier by restoring the inhibitory effect of GRK2 and β-arrestin 2 on ERK1/2-NF-κB.
Phytotherapy research : PTR
Jiang M,Tang C,Yang M,Li Y,Wang W,Wang C,Wei W,Chen J
Wed Feb 01 00:00:00 EST 2023
The High Level of RANKL Improves IκB/p65/Cyclin D1 Expression and Decreases p-Stat5 Expression in Firm Udder of Dairy Goats.
International journal of molecular sciences
Gao Z,Shao D,Zhao C,Liu H,Zhao X,Wei Q,Ma B
Tue May 16 00:00:00 EDT 2023
Knockdown of the SELENOK gene induces ferroptosis in cervical cancer cells.
Metallomics : integrated biometal science
Abdurahman A,Li Y,Jia SZ,Xu XW,Lin SJ,Ouyang P,Jun He Z,Zhang ZH,Liu Q,Xu Y,Song GL
Mon Apr 03 00:00:00 EDT 2023
Identification of miR-30c-5p as a tumor suppressor by targeting the m6 A reader HNRNPA2B1 in ovarian cancer.
Cancer medicine
Wu Q,Li G,Gong L,Cai J,Chen L,Xu X,Liu X,Zhao J,Zeng Y,Gao R,Yu L,Wang Z
Wed Feb 01 00:00:00 EST 2023
Scutellarin Acts via MAPKs Pathway to Promote M2 Polarization of Microglial Cells.
Molecular neurobiology
Chen HL,Yang L,Zhang XL,Jia QY,Duan ZD,Li JJ,Zheng LY,Liu TT,Qi Z,Yuan Y,Wu CY
Tue Aug 01 00:00:00 EDT 2023
Marein reduces lipid levels via modulating the PI3K/AKT/mTOR pathway to induce lipophagy.
Journal of ethnopharmacology
Zhang PP,Zhuo BY,Duan ZW,Li X,Huang SL,Cao Q,Zhao T,Wei SL,Hu XH,Zhang Y
Thu Aug 10 00:00:00 EDT 2023
Morphometric analysis of the size-adjusted linear dimensions of the skull landmarks revealed craniofacial dysmorphology in Mid1-cKO mice.
BMC genomics
Liang Y,Song C,Li J,Li T,Zhang C,Zou Y
Thu Feb 09 00:00:00 EST 2023
Methionine sulfoxide suppresses adipogenic differentiation by regulating the mitogen-activated protein kinase signaling pathway.
Cell biology international
Qin D,Lei Y,Xie W,Zheng Q,Peng Z,Liu Y,Dai B,Ma T,Wei P,Gao C,Guo X,Gao J,Zhao J,Du J,Zeng Q,Zhang Z,Dong X,Shen H
Wed Mar 01 00:00:00 EST 2023
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Inflammation
Li K,Feng Z,Wang L,Ma X,Wang L,Liu K,Geng X,Peng C
Thu Jun 01 00:00:00 EDT 2023
The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB.
Cell reports
Fei X,Huang J,Li F,Wang Y,Shao Z,Dong L,Wu Y,Li B,Zhang X,Lv B,Zhao Y,Weng Q,Chen K,Zhang M,Yang S,Zhang C,Zhang M,Li W,Ying S,Sun Q,Chen Z,Shen H
Tue Jun 27 00:00:00 EDT 2023
The FBXO32/ATR/ATM axis acts as a molecular switch to control the sensitivity of osteosarcoma cells to irradiation through its regulation of EXO1 expression.
Acta biochimica et biophysica Sinica
Lu Y,Huang P,Li Y,Liu W,Li J,Zhao R,Feng H,Shi C,Cao G
Wed May 24 00:00:00 EDT 2023
Ligation to Scavenging Strategy Enables On-Demand Termination of Targeted Protein Degradation.
Journal of the American Chemical Society
Jin Y,Fan J,Wang R,Wang X,Li N,You Q,Jiang Z
Wed Apr 05 00:00:00 EDT 2023
CD98 regulates the phosphorylation of HER2 and a bispecific anti-HER2/CD98 antibody inhibits the growth signal of human breast cancer cells.
Genes to cells : devoted to molecular & cellular mechanisms
Yamasaki A,Maruyama-Takahashi K,Nishida K,Okazaki S,Okita K,Akiyama Y,Suzuki H,Endo Y,Masuko K,Masuko T,Tomioka Y
Mon May 01 00:00:00 EDT 2023
PARM1 Drives Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension via AKT/FOXO3A Axis.
International journal of molecular sciences
He Z,Chang T,Chen Y,Wang H,Dai L,Zeng H
Tue Mar 28 00:00:00 EDT 2023
Upregulation of CSNK1A1 induced by ITGB5 confers to hepatocellular carcinoma resistance to sorafenib in vivo by disrupting the EPS15/EGFR complex.
Pharmacological research
Gu L,Jin X,Liang H,Yang C,Zhang Y
Thu Jun 01 00:00:00 EDT 2023
Mesenchymal Stem Cell-Derived Exosomal miR-150-3p Affects Intracerebral Hemorrhage By Regulating TRAF6/NF-κB Axis, Gut Microbiota and Metabolism.
Stem cell reviews and reports
Sun J,Xu G
Tue Aug 01 00:00:00 EDT 2023
Leonurine Regulates Hippocampal Nerve Regeneration in Rats with Chronic and Unpredictable Mild Stress by Activating SHH/GLI Signaling Pathway and Restoring Gut Microbiota and Microbial Metabolic Homeostasis.
Neural plasticity
Meng P,Zhang X,Li D,Yang H,Lin X,Zhao H,Li P,Wang Y,Wang X,Ge J
Wed Jan 18 00:00:00 EST 2023
Soluble TREM-like Transcript-1 Acts as a Damage-Associated Molecular Pattern through the TLR4/MD2 Pathway Contributing to Immune Dysregulation during Sepsis.
Journal of immunology (Baltimore, Md. : 1950)
Chang CM,Cheng KH,Wei TY,Lu MP,Chen YC,Lu YT
Mon May 01 00:00:00 EDT 2023
MSC-EXO and tempol ameliorate bronchopulmonary dysplasia in newborn rats by activating HIF-1α.
Pediatric pulmonology
Wang J,Zhang A,Huang F,Xu J,Zhao M
Mon May 01 00:00:00 EDT 2023
Sleeve gastrectomy decreased hepatic lipid accumulation by inducing autophagy via AMPK/mTOR pathway.
Biochemical and biophysical research communications
Zeng R,Zeng Y,Wang Q,Li X,Liu J,Li B,Zhang G,Hu S
Sun Apr 23 00:00:00 EDT 2023
Yi-Shen-Xie-Zhuo formula alleviates cisplatin-induced AKI by regulating inflammation and apoptosis via the cGAS/STING pathway.
Journal of ethnopharmacology
Qi J,Luo Q,Zhang Q,Wu M,Zhang L,Qin L,Xue Q,Nie X
Mon Jun 12 00:00:00 EDT 2023
Effects of icariin and curcumol on autophagy, ferroptosis, and lipid metabolism based on miR-7/m-TOR/SREBP1 pathway on prostate cancer.
BioFactors (Oxford, England)
Xu W,Ding J,Li B,Sun T,You X,He Q,Sheng W
Wed Mar 01 00:00:00 EST 2023
Elevated expression of myosin VI contributes to breast cancer progression via MAPK/ERK signaling pathway.
Cellular signalling
Zhan XJ,Wang R,Kuang XR,Zhou JY,Hu XL
Thu Jun 01 00:00:00 EDT 2023
Identification of immune signatures in Parkinson's disease based on co-expression networks.
Frontiers in genetics
Dong X,Li Y,Li Q,Li W,Wu G
Sat Feb 04 00:00:00 EST 2023
Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration.
Neuron
Festa BP,Siddiqi FH,Jimenez-Sanchez M,Won H,Rob M,Djajadikerta A,Stamatakou E,Rubinsztein DC
Wed Jul 05 00:00:00 EDT 2023
SFRP1 Expression is Inversely Associated With Metastasis Formation in Canine Mammary Tumours.
Journal of mammary gland biology and neoplasia
Seitz J,Bilsland A,Puget C,Baasner I,Klopfleisch R,Stein T
Tue Jul 04 00:00:00 EDT 2023
Activation of Nrf2 signalling pathway by tectoridin protects against ferroptosis in particulate matter-induced lung injury.
British journal of pharmacology
Dong T,Fan X,Zheng N,Yan K,Hou T,Peng L,Ci X
Sun Oct 01 00:00:00 EDT 2023
Piperine ameliorates psoriatic skin inflammation by inhibiting the phosphorylation of STAT3.
International immunopharmacology
Lu H,Gong H,Du J,Gao W,Xu J,Cai X,Yang Y,Xiao H
Thu Jun 01 00:00:00 EDT 2023
The G allele of SNP rs3922 reduces the binding affinity between IGF2BP3 and CXCR5 correlating with a lower antibody production.
European journal of immunology
Duan Z,Ma L,Jin J,Ma L,Ye L,Wu J,Luo Y
Tue Aug 01 00:00:00 EDT 2023
The choleretic role of tauroursodeoxycholic acid exacerbates alpha-naphthylisothiocyanate induced cholestatic liver injury through the FXR/BSEP pathway.
Journal of applied toxicology : JAT
Zhao J,Song G,Weng F,Li Y,Zou B,Jin J,Yan D,Sun X,Liu C,Qiu FR
Sat Jul 01 00:00:00 EDT 2023
Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression.
Journal of ethnopharmacology
Liu EY,Yang CL,Tsai JC,Cheng HY,Peng WH
Mon Jun 12 00:00:00 EDT 2023
Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2.
Journal of medicinal chemistry
Zhang Y,Yang H,Li B,Li J,Li H,Shi Q,Li B,Wang Z,Zheng J,Zhang Y,Dong H,Huang X,Wang Y
Thu Jun 08 00:00:00 EDT 2023
Aminosalicylates target GPR35, partly contributing to the prevention of DSS-induced colitis.
European journal of pharmacology
Otkur W,Wang J,Hou T,Liu F,Yang R,Li Y,Xiang K,Pei S,Qi H,Lin H,Zhou H,Zhang X,Piao HL,Liang X
Thu Jun 15 00:00:00 EDT 2023
Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway.
Journal of ethnopharmacology
Zhu Y,Han Q,Wang L,Wang B,Chen J,Cai B,Wu C,Zhu X,Liu F,Han D,Dong H,Jia Y,Liu Y
Mon Jan 30 00:00:00 EST 2023
Soyasaponin I alleviates hypertensive intracerebral hemorrhage by inhibiting the renin-angiotensin-aldosterone system.
Clinical and experimental hypertension (New York, N.Y. : 1993)
Li W,Li SG,Li L,Yang LJ,Li ZS,Li X,Ye AY,Xiong Y,Zhang Y,Xiong YY
Sun Dec 31 00:00:00 EST 2023
MiR-24-3p/Dio3 axis is essential for BDE47 to induce local thyroid hormone disorder and neurotoxicity.
Toxicology
Liu M,Yu Z,Zhao Z,Yang F,Zhou M,Wang C,Tian X,Zhang B,Liang G,Liu X,Shao J
Thu Jun 01 00:00:00 EDT 2023
High SNRPA1 expression leads to poor prognosis in patients with lung adenocarcinoma.
The clinical respiratory journal
Yang JJ,Yang YJ,Gu YL,Tong L,Liu YF,Zhang JG
Tue Aug 01 00:00:00 EDT 2023
The long noncoding RNA CIRBIL is a regulator of steroidogenesis in mice.
Reproductive biology
Huang X,Liu X,Zhang X,Yang Y,Gao H,Gao J,Bao H,Zhao L,Yang G,Zhang Y,Liu D
Fri Sep 01 00:00:00 EDT 2023
Characterization of dominant-negative growth hormone receptor variants reveals a potential therapeutic target for short stature.
European journal of endocrinology
Andrews A,Cottrell E,Maharaj A,Ladha T,Williams J,Schilbach K,Kaisinger LR,Perry JRB,Metherell LA,McCormick PJ,Storr HL
Tue Apr 04 00:00:00 EDT 2023
DNA repair mechanisms that promote insertion-deletion events during immunoglobulin gene diversification.
Science immunology
Hao Q,Zhan C,Lian C,Luo S,Cao W,Wang B,Xie X,Ye X,Gui T,Voena C,Pighi C,Wang Y,Tian Y,Wang X,Dai P,Cai Y,Liu X,Ouyang S,Sun S,Hu Q,Liu J,Ye Y,Zhao J,Lu A,Wang JY,Huang C,Su B,Meng FL,Chiarle R,Pan-Hammarström Q,Yeap LS
Fri Mar 31 00:00:00 EDT 2023
Heat-Killed Lacticaseibacillus paracasei Repairs Lipopolysaccharide-Induced Intestinal Epithelial Barrier Damage via MLCK/MLC Pathway Activation.
Nutrients
Xie Z,Zhang G,Liu R,Wang Y,Tsapieva AN,Zhang L,Han J
Tue Apr 04 00:00:00 EDT 2023
HERC2 promotes inflammation-driven cancer stemness and immune evasion in hepatocellular carcinoma by activating STAT3 pathway.
Journal of experimental & clinical cancer research : CR
Liu Y,Xu Q,Deng F,Zheng Z,Luo J,Wang P,Zhou J,Lu X,Zhang L,Chen Z,Zhang Q,Chen Q,Zuo D
Wed Feb 01 00:00:00 EST 2023
Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis.
Journal of orthopaedic translation
Chen Y,Liu Y,Jiang K,Wen Z,Cao X,Wu S
Wed Mar 01 00:00:00 EST 2023
Oridonin promotes endoplasmic reticulum stress via TP53-repressed TCF4 transactivation in colorectal cancer.
Journal of experimental & clinical cancer research : CR
Zhou F,Gao H,Shang L,Li J,Zhang M,Wang S,Li R,Ye L,Yang S
Mon Jun 19 00:00:00 EDT 2023
E. coli Nissle 1917 ameliorates mitochondrial injury of granulosa cells in polycystic ovary syndrome through promoting gut immune factor IL-22 via gut microbiota and microbial metabolism.
Frontiers in immunology
Luo M,Chen Y,Pan X,Chen H,Fan L,Wen Y
Tue Jun 13 00:00:00 EDT 2023
AAV9-Tspyl2 gene therapy retards bleomycin-induced pulmonary fibrosis by modulating downstream TGF-β signaling in mice.
Cell death & disease
Zhang S,Tong X,Liu S,Huang J,Zhang L,Zhang T,Wang D,Fan H
Fri Jun 30 00:00:00 EDT 2023
Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function.
Acta pharmacologica Sinica
Sun JX,Zhu KY,Wang YM,Wang DJ,Zhang MZ,Sarlus H,Benito-Cuesta I,Zhao XQ,Zou ZF,Zhong QY,Feng Y,Wu S,Wang YQ,Harris RA,Wang J
Sat Apr 01 00:00:00 EDT 2023
Banoxantrone Coordinated Metal-Organic Framework for Photoacoustic Imaging-Guided High Intensity Focused Ultrasound Therapy.
Advanced healthcare materials
Sun T,Li J,Zeng C,Luo C,Luo X,Li H
Sun Jan 01 00:00:00 EST 2023
Cancer-associated fibroblasts suppressed ferroptosis in glioblastoma via upregulating lncRNA DLEU1.
American journal of physiology. Cell physiology
Zhao J,Yang S,Lv C,Liu Y
Mon May 01 00:00:00 EDT 2023
Lycium barbarum Polysaccharides Regulating miR-181/Bcl-2 Decreased Autophagy of Retinal Pigment Epithelium with Oxidative Stress.
Oxidative medicine and cellular longevity
Yang YJ,Wang Y,Deng Y,Liu XQ,Lu J,Peng J,Li J,Zhou YS,Zhu HA,Li B,Qin YH,Peng QH
Wed Jan 18 00:00:00 EST 2023
YY1 (Yin-Yang 1), a transcription factor regulating systemic inflammation, is involved in cognitive impairment of depression.
Psychiatry and clinical neurosciences
Lu J,Jin K,Jiao J,Liu R,Mou T,Chen B,Zhang Z,Jiang C,Zhao H,Wang Z,Zhou R,Huang M
Wed Mar 01 00:00:00 EST 2023
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Nucleic acids research
Zhu X,Huang B,Zhao F,Lian J,He L,Zhang Y,Ji L,Zhang J,Yan X,Zeng T,Ma C,Liang Y,Zhang C,Lin J
Tue Mar 21 00:00:00 EDT 2023
Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis.
Arteriosclerosis, thrombosis, and vascular biology
Li S,Wang W,Lin L,Yang L,Cai Y,Yang X,Zhang T,Xiao C,Yan H,Gao N,Zhao J
Wed Feb 01 00:00:00 EST 2023
Natural Oncolysis of Enterovirus 71 in Antitumor Therapy of Colorectal Cancer.
Advanced biology
Ruan Z,Chi J,Kong Y,Li C,Ruan X,Zhou X,Chen Y,Li Y,Luo Z
Sat Jul 01 00:00:00 EDT 2023
Donor graft METTL3 gene transfer ameliorates rat liver transplantation ischemia-reperfusion injury by enhancing HO-1 expression in an m6A-dependent manner.
Clinical immunology (Orlando, Fla.)
Xiang S,Wang Y,Lei D,Luo Y,Peng D,Zong K,Liu Y,Huang Z,Mo S,Pu X,Zheng J,Wu Z
Thu Jun 01 00:00:00 EDT 2023
Lactobacillus johnsonii L531 Ameliorates Salmonella enterica Serovar Typhimurium Diarrhea by Modulating Iron Homeostasis and Oxidative Stress via the IRP2 Pathway.
Nutrients
Chen K,Wang J,Guo L,Wang J,Yang L,Hu T,Zhao Y,Wang X,Zhu Y
Thu Feb 23 00:00:00 EST 2023
Sustainably released nanoparticle-based rhynchophylline limits pulmonary fibrosis by inhibiting the TEK-PI3K/AKT signaling pathway.
Translational lung cancer research
Wang S,Huang Z,Liu Y,Sun H,Zhou Y,Shi J
Fri Mar 31 00:00:00 EDT 2023
Sertaconazole nitrate targets IDO1 and regulates the MAPK signaling pathway to induce autophagy and apoptosis in CRC cells.
European journal of pharmacology
Yang Y,Jin Y,Yin L,Liu P,Zhu L,Gao H
Sun Mar 05 00:00:00 EST 2023
PFKFB2 is a favorable prognostic biomarker for colorectal cancer by suppressing metastasis and tumor glycolysis.
Journal of cancer research and clinical oncology
Liu F,Wei X,Chen Z,Chen Y,Hu P,Jin Y
Fri Sep 01 00:00:00 EDT 2023
Role of SUMOylation of STAT1 in tubular epithelial‑mesenchymal transition induced by high glucose.
Molecular medicine reports
Gu C,Gao F,Zhang S,Kang L,Zhang W,Feng X,Liu J,Tian Y,Wei Q,Du Y,Xing Y,Liu Q,Liu S
Wed Feb 01 00:00:00 EST 2023
Pemetrexed induces ROS generation and cellular senescence by attenuating TS-mediated thymidylate metabolism to reverse gefitinib resistance in NSCLC.
Journal of cellular and molecular medicine
Chen Y,Zhang C,Jin S,Li J,Dai J,Zhang Z,Guo R
Sat Jul 01 00:00:00 EDT 2023
Liraglutide abrogates nephrotoxic effects of chemotherapies.
Pharmacological research
Xu C,Lu C,Wang Z,Hu X,Li S,Xie Y,Qiu Y,Cao R,Li Y,Yang J
Wed Mar 01 00:00:00 EST 2023
Prediction and Verification of Curcumin as a Potential Drug for Inhibition of PDCoV Replication in LLC-PK1 Cells.
International journal of molecular sciences
Wang X,Wang X,Zhang J,Shan Q,Zhu Y,Xu C,Wang J
Mon Mar 20 00:00:00 EDT 2023
PRPF19 Limits Porcine Epidemic Diarrhea Virus Replication through Targeting and Degrading Viral Capsid Protein.
Journal of virology
Zhai X,Kong N,Wang C,Qin W,Dong S,Zhai H,Yang X,Ye C,Ye M,Li G,Tong W,Liu C,Zheng H,Yu H,Zhang W,Yang X,Tong G,Shan T
Tue Jan 31 00:00:00 EST 2023
A novel nano material for anti-cerebral ischaemia: preparation and application of borneol angelica polysaccharide liposomes.
Journal of liposome research
Ding H,Wang K,He LQ,Yang XY,Huang HH,Liu WL,Xiao C,Du ZX,Yu L,Zhang W
Thu Jun 01 00:00:00 EDT 2023
Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS.
The Journal of toxicological sciences
Luo J,Liu J,Mou Y,Luo F,Liao Q,Liao Y
Fri Jun 02 00:00:00 EDT 2023
Southern rice black-streaked dwarf virus induces incomplete autophagy for persistence in gut epithelial cells of its vector insect.
PLoS pathogens
Zhang L,Liu W,Wu N,Wang H,Zhang Z,Liu Y,Wang X
Sun Jan 01 00:00:00 EST 2023
Disrupted in renal carcinoma 2 (DIRC2/SLC49A4) is an H+-driven lysosomal pyridoxine exporter.
Life science alliance
Akino S,Yasujima T,Yamashiro T,Yuasa H
Wed Feb 01 00:00:00 EST 2023
NLRP3 Inflammasome Mediates Silica-induced Lung Epithelial Injury and Aberrant Regeneration in Lung Stem/Progenitor Cell-derived Organotypic Models.
International journal of biological sciences
Zhou H,Zhang Q,Huang W,Zhou S,Wang Y,Zeng X,Wang H,Xie W,Kong H
Tue Apr 18 00:00:00 EDT 2023
Sevoflurane-induced P300 promotes neuron apoptosis via Sp1/CDK9 pathway.
Clinical and experimental pharmacology & physiology
Zhou X,Liu C,Xia D
Sat Jul 01 00:00:00 EDT 2023
Dickkopf-1 promotes vascular smooth muscle cell foam cell formation and atherosclerosis development through CYP4A11/SREBP2/ABCA1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li X,Zheng T,Zhang Y,Zhao Y,Liu F,Dai S,Liu X,Zhang M
Tue Aug 01 00:00:00 EDT 2023
ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate.
Metabolites
Yang Y,Zhang Z,Li W,Li L,Zhou Y,Du W
Mon Apr 10 00:00:00 EDT 2023
USP22 suppresses the NLRP3 inflammasome by degrading NLRP3 via ATG5-dependent autophagy.
Autophagy
Di Q,Zhao X,Tang H,Li X,Xiao Y,Wu H,Wu Z,Quan J,Chen W
Wed Mar 01 00:00:00 EST 2023
USP22 suppresses the NLRP3 inflammasome by degrading NLRP3 via ATG5-dependent autophagy.
Autophagy
Di Q,Zhao X,Tang H,Li X,Xiao Y,Wu H,Wu Z,Quan J,Chen W
Wed Mar 01 00:00:00 EST 2023
Flavivirus prM interacts with MDA5 and MAVS to inhibit RLR antiviral signaling.
Cell & bioscience
Sui L,Zhao Y,Wang W,Chi H,Tian T,Wu P,Zhang J,Zhao Y,Wei ZK,Hou Z,Zhou G,Wang G,Wang Z,Liu Q
Fri Jan 13 00:00:00 EST 2023
Downregulated annexin A1 expression correlates with poor prognosis, metastasis, and immunosuppressive microenvironment in Ewing's sarcoma.
Aging
Shi X,Wu Y,Tang L,Ni H,Xu Y
Tue Mar 28 00:00:00 EDT 2023
Integrated analysis of Dendrobium nobile extract Dendrobin A against pancreatic ductal adenocarcinoma based on network pharmacology, bioinformatics, and validation experiments.
Frontiers in pharmacology
Xu X,Yu Y,Yang L,Wang B,Fan Y,Ruan B,Zhang X,Dai H,Mei W,Jie W,Zheng S
Tue Mar 21 00:00:00 EDT 2023
Ambra1 modulates the sensitivity of mantle cell lymphoma to palbociclib by regulating cyclin D1.
Scientific reports
Jiang Z,Zhang A,Wei W,Li S
Wed May 24 00:00:00 EDT 2023
The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease.
Blood
Cheng Q,Wang D,Lai X,Liu Y,Zuo Y,Zhang W,Lei L,Chen J,Liu H,Wang Y,Liu H,Zheng H,Wu D,Xu Y
Thu Mar 23 00:00:00 EDT 2023
Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer.
Chinese medicine
Wu R,Xi Z,Liu M,Ren H,Dai R,Jiang X,Nik Nabil WN,Wang Y,Feng J,Chai Q,Dong Q,Xu H
Sun May 28 00:00:00 EDT 2023
Hypoxic Preconditioning Enhances Cellular Viability and Migratory Ability: Role of DANCR/miR-656-3p/HIF-1α Axis in Placental Mesenchymal Stem Cells.
Stem cells (Dayton, Ohio)
Haoran S,Zhishan J,Yan M,Ruilin M,Jianjian C,Zejun Y,Jianwen Z,Hui G,Yin Z
Fri Sep 15 00:00:00 EDT 2023
Discovery of bipyridine amide derivatives targeting pRXRα-PLK1 interaction for anticancer therapy.
European journal of medicinal chemistry
Chen J,Zhao T,He F,Zhong Y,Wang S,Tang Z,Qiu Y,Wu Z,Fang M
Mon Jun 05 00:00:00 EDT 2023
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation.
Autophagy
Cai W,Hu M,Li C,Wu R,Lu D,Xie C,Zhang W,Li T,Shen S,Huang H,Qiu W,Liu Q,Lu Y,Lu Z
Sat Apr 01 00:00:00 EDT 2023
Silencing mouse circular RNA circSlc8a1 by circular antisense cA-circSlc8a1 induces cardiac hepatopathy.
Molecular therapy : the journal of the American Society of Gene Therapy
Wu N,Li F,Yang W,Du WW,Awan FM,Zhang C,Lyu J,Misir S,Zeng K,Eshaghi E,Yang BB
Wed Jun 07 00:00:00 EDT 2023
N6-methyladenosine reader IGF2BP3 as a prognostic Biomarker contribute to malignant progression of glioma.
Translational cancer research
Zheng X,Li S,Yu J,Dai C,Yan S,Chen G,Sun C
Fri Apr 28 00:00:00 EDT 2023
Amphibian pore-forming protein βγ-CAT drives extracellular nutrient scavenging under cell nutrient deficiency.
iScience
Liu LZ,Liu L,Shi ZH,Bian XL,Si ZR,Wang QQ,Xiang Y,Zhang Y
Fri May 19 00:00:00 EDT 2023
USP2 promotes cell proliferation and metastasis in choroidal melanoma via stabilizing Snail.
Journal of cancer research and clinical oncology
Wei C,Zhao X,Zhang H,Wang L
Fri Sep 01 00:00:00 EDT 2023
The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma.
Cell death and differentiation
Wang S,Wang T,Zhang X,Cheng S,Chen C,Yang G,Wang F,Wang R,Zhang Q,Yang D,Zhang Y,Liu S,Qin H,Liu Q,Liu H
Sat Jul 01 00:00:00 EDT 2023
Macrophage Migration Inhibitory Factor Promotes Expression of Matrix Metalloproteinases 1 and 3 in Spinal Cord Astrocytes following Gecko Tail Amputation.
Journal of integrative neuroscience
Zhang H,Sun C,He B,Zhang X,Hao H,Hou Y,Li A,Wang Y,Wang Y
Fri Feb 10 00:00:00 EST 2023
p53 directly downregulates the expression of CDC20 to exert anti-tumor activity in mantle cell lymphoma.
Experimental hematology & oncology
Chen Y,Yang P,Wang J,Gao S,Xiao S,Zhang W,Zhu M,Wang Y,Ke X,Jing H
Tue Mar 07 00:00:00 EST 2023
SLC7A14 imports GABA to lysosomes and impairs hepatic insulin sensitivity via inhibiting mTORC2.
Cell reports
Jiang X,Liu K,Jiang H,Yin H,Wang ED,Cheng H,Yuan F,Xiao F,Wang F,Lu W,Peng B,Shu Y,Li X,Chen S,Guo F
Tue Jan 31 00:00:00 EST 2023
Lateral septum adenosine A2A receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula.
Nature communications
Wang M,Li P,Li Z,da Silva BS,Zheng W,Xiang Z,He Y,Xu T,Cordeiro C,Deng L,Dai Y,Ye M,Lin Z,Zhou J,Zhou X,Ye F,Cunha RA,Chen J,Guo W
Wed Apr 05 00:00:00 EDT 2023
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.
Psychopharmacology
Liao D,Shangguan D,Wu Y,Chen Y,Liu N,Tang J,Yao D,Shi Y
Mon May 01 00:00:00 EDT 2023
Preparation of nanocomposite membranes loaded with taxifolin liposome and its mechanism of wound healing in diabetic mice.
International journal of biological macromolecules
Ding Q,Ding C,Liu X,Zheng Y,Zhao Y,Zhang S,Sun S,Peng Z,Liu W
Fri Jun 30 00:00:00 EDT 2023
Exosomal lncRNA HOTAIR induces PDL1+ B cells to impede anti-tumor immunity in colorectal cancer.
Biochemical and biophysical research communications
Xie Z,Xia J,Jiao M,Zhao P,Wang Z,Lin S,Xing Y,Li Y,Lu Z,Zhong Z,Miao C,Zhou P,Qian J,Wang L,Zhang D,Gu J,Chu Y,Liu R
Sun Feb 12 00:00:00 EST 2023
miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.
Life sciences
Wen T,Duan Y,Gao D,Zhang X,Zhang X,Liang L,Yang Z,Zhang P,Zhang J,Sun J,Feng Y,Zheng Q,Han H,Yan X
Tue Aug 01 00:00:00 EDT 2023
Mechanism of autophagy mediated by IGF-1 signaling pathway in the neurotoxicity of lead in pubertal rats.
Ecotoxicology and environmental safety
Zhang B,Li H,Wang Y,Li Y,Zhou Z,Hou X,Zhang X,Liu T
Wed Feb 01 00:00:00 EST 2023
Subconjunctival Administration of Mesenchymal Stem Cells Alleviates Ocular Inflammation in a Murine Model of Corneal Alkali Burn.
Stem cells (Dayton, Ohio)
Chen M,Chen X,Li X,Wang J,Wu J,Wang Q,Huang Y,Li Z,Wang L
Thu Jun 15 00:00:00 EDT 2023
Aquaporin 1 is a prognostic marker and inhibits tumour progression through downregulation of Snail expression in intrahepatic cholangiocarcinoma.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Zhuang MQ,Jiang XL,Liu WD,Xie QH,Wang P,Dong LW,Hu HP,Zhou HB,Zhou YB
Tue Aug 01 00:00:00 EDT 2023
The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.
Cell reports
Fan G,Wang F,Chen Y,Zheng Q,Xiong J,Lv Q,Wu K,Xiong J,Wei L,Li D,Zhang J,Zhang W,Li F
Tue Jan 31 00:00:00 EST 2023
Traxoprodil Produces Antidepressant-Like Behaviors in Chronic Unpredictable Mild Stress Mice through BDNF/ERK/CREB and AKT/FOXO/Bim Signaling Pathway.
Oxidative medicine and cellular longevity
Wang Y,Liang Z,Song W,Qin Y,Todd N,Gao M
Mon Feb 27 00:00:00 EST 2023
Loureirin C inhibits ferroptosis after cerebral ischemia reperfusion through regulation of the Nrf2 pathway in mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Liu Y,Mi Y,Wang Y,Meng Q,Xu L,Liu Y,Zhou D,Wang Y,Liang D,Li W,Li N,Hou Y
Mon May 01 00:00:00 EDT 2023
Tabersonine, a natural NLRP3 inhibitor, suppresses inflammasome activation in macrophages and attenuate NLRP3-driven diseases in mice.
Acta pharmacologica Sinica
Xu HW,Li WF,Hong SS,Shao JJ,Chen JH,Chattipakorn N,Wu D,Luo W,Liang G
Thu Jun 01 00:00:00 EDT 2023
ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer.
Developmental cell
Yi J,Wang L,Du J,Wang M,Shen H,Liu Z,Qin Y,Liu J,Hu G,Xiao R,Ding J,Chen X,Wang H,Huang H,Ouyang G,Liu W
Mon May 08 00:00:00 EDT 2023
FTO-dependent m6A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke.
Nature communications
Li B,Xi W,Bai Y,Liu X,Zhang Y,Li L,Bian L,Liu C,Tang Y,Shen L,Yang L,Gu X,Xie J,Zhou Z,Wang Y,Yu X,Wang J,Chao J,Han B,Yao H
Mon Jan 30 00:00:00 EST 2023
9-Butyl-Harmol Exerts Antiviral Activity against Newcastle Disease Virus through Targeting GSK-3β and HSP90β.
Journal of virology
Wang C,Wang T,Hu R,Duan L,Hou Q,Han Y,Dai J,Wang W,Ren S,Liu H,Wang X,Xiao S,Li N,Wang J,Yang Z
Thu Mar 30 00:00:00 EDT 2023
Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function.
Acta pharmacologica Sinica
Zhu XX,Wang X,Jiao SY,Liu Y,Shi L,Xu Q,Wang JJ,Chen YE,Zhang Q,Song YT,Wei M,Yu BQ,Fielitz J,Gonzalez FJ,Du J,Qu AJ
Wed Nov 01 00:00:00 EDT 2023
YTHDF2 orchestrates tumor-associated macrophage reprogramming and controls antitumor immunity through CD8+ T cells.
Nature immunology
Ma S,Sun B,Duan S,Han J,Barr T,Zhang J,Bissonnette MB,Kortylewski M,He C,Chen J,Caligiuri MA,Yu J
Wed Feb 01 00:00:00 EST 2023
COPS3 inhibition promotes cell proliferation blockage and anoikis via regulating PFKFB3 in osteosarcoma cancer cells.
European journal of pharmacology
Zhang F,Li Q,Zhang Y,Li N,Rao M,Li S,Ai Z,Yan S,Tian Z
Sat Jul 15 00:00:00 EDT 2023
FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels.
The EMBO journal
Elcocks H,Brazel AJ,McCarron KR,Kaulich M,Husnjak K,Mortiboys H,Clague MJ,Urbé S
Mon Jul 03 00:00:00 EDT 2023
TLR2-mediated NF-κB signaling pathway is involved in PPV1-induced apoptosis in PK-15 cells.
Veterinary research communications
Xu M,Jin X,Zhang C,Liao H,Wang P,Zhou Y,Song Y,Xia L,Wang L
Thu Jun 01 00:00:00 EDT 2023
Selenoprotein Gene mRNA Expression Evaluation During Renal Ischemia-Reperfusion Injury in Rats and Ebselen Intervention Effects.
Biological trace element research
Wu Y,Shi H,Xu Y,Wen R,Gong M,Hong G,Xu S
Sat Apr 01 00:00:00 EDT 2023
Characterization and mechanisms of radioresistant lung squamous cell carcinoma cell lines.
Thoracic cancer
Pan L,Wu Q,Wang Y,Ma S,Zhang S
Mon May 01 00:00:00 EDT 2023
Hesperidin enhances intestinal barrier function in Caco-2 cell monolayers via AMPK-mediated tight junction-related proteins.
FEBS open bio
Park HY,Yu JH
Wed Mar 01 00:00:00 EST 2023
Podocyte-specific deletion of ubiquitin carboxyl-terminal hydrolase L1 causes podocyte injury by inducing endoplasmic reticulum stress.
Cellular and molecular life sciences : CMLS
Hu Y,Qi C,Shi J,Tan W,Zhao Z,Xu Y,Wu H,Zhang Z
Thu Mar 23 00:00:00 EDT 2023
Antisense lncRNA-RP11-498C9.13 promotes bladder cancer progression by enhancing reactive oxygen species-induced mitophagy.
The journal of gene medicine
Song W,Li Z,Yang K,Gao Z,Zhou Q,Li P
Fri Sep 01 00:00:00 EDT 2023
Dietary fiber alters immunity and intestinal barrier function of different breeds of growing pigs.
Frontiers in immunology
Ding S,Cheng Y,Azad MAK,Dong H,He J,Huang P,Kong X
Tue Mar 07 00:00:00 EST 2023
Excessive serine from the bone marrow microenvironment impairs megakaryopoiesis and thrombopoiesis in Multiple Myeloma.
Nature communications
Kuang C,Xia M,An G,Liu C,Hu C,Zhang J,Liu Z,Meng B,Su P,Xia J,Guo J,Zhu Y,Liu X,Wu X,Shen Y,Feng X,He Y,Li J,Qiu L,Zhou J,Zhou W
Thu Apr 13 00:00:00 EDT 2023
RGS12 represses oral squamous cell carcinoma by driving M1 polarization of tumor-associated macrophages via controlling ciliary MYCBP2/KIF2A signaling.
International journal of oral science
Yuan G,Yang S,Yang S
Thu Feb 16 00:00:00 EST 2023
Radiation resistance of cancer cells caused by mitochondrial dysfunction depends on SIRT3-mediated mitophagy.
The FEBS journal
Wei Y,Xiao G,Xu H,Sun X,Shi Y,Wang F,Kang J,Peng J,Zhou F
Sat Jul 01 00:00:00 EDT 2023
SARS-CoV-2 Nsp8 induces mitophagy by damaging mitochondria.
Virologica Sinica
Zong S,Wu Y,Li W,You Q,Peng Q,Wang C,Wan P,Bai T,Ma Y,Sun B,Qiao J
Tue Aug 01 00:00:00 EDT 2023
Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy.
Journal of nanobiotechnology
Zhu TT,Wang H,Gu HW,Ju LS,Wu XM,Pan WT,Zhao MM,Yang JJ,Liu PM
Fri Feb 10 00:00:00 EST 2023
SIAH1/CTR9 axis promotes the epithelial-mesenchymal transition of hepatocellular carcinoma.
Carcinogenesis
Liu Z,Luo P,Cao K,Hu Q,Hu B,Cui L,Wang X,Shi H,Zhang B,Wang R
Sat Jun 24 00:00:00 EDT 2023
Upregulation of carbonic anhydrase 1 beneficial for depressive disorder.
Acta neuropathologica communications
Cheng K,Wang Y,He Y,Tian Y,Li J,Chen C,Xu X,Wu Z,Yu H,Chen X,Wu Y,Song W,Dong Z,Xu H,Xie P
Mon Apr 03 00:00:00 EDT 2023
Identification of glutamyl-prolyl-tRNA synthetase as a new therapeutic target in hepatocellular carcinoma via a novel bioinformatic approach.
Journal of gastrointestinal oncology
Shu J,Luo P,Zhang G,Gao Y
Sat Apr 29 00:00:00 EDT 2023
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
The FEBS journal
Kuang H,Sun X,Liu Y,Tang M,Wei Y,Shi Y,Li R,Xiao G,Kang J,Wang F,Peng J,Xu H,Zhou F
Sat Jul 01 00:00:00 EDT 2023
Tumor-intrinsic PRC2 inactivation drives a context-dependent immune-desert microenvironment and is sensitized by immunogenic viruses.
The Journal of clinical investigation
Yan J,Chen Y,Patel AJ,Warda S,Lee CJ,Nixon BG,Wong EW,Miranda-Román MA,Yang N,Wang Y,Pachai MR,Sher J,Giff E,Tang F,Khurana E,Singer S,Liu Y,Galbo PM,Maag JL,Koche RP,Zheng D,Antonescu CR,Deng L,Li MO,Chen Y,Chi P
Thu Sep 01 00:00:00 EDT 2022
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.
Neuron
LaForce GR,Farr JS,Liu J,Akesson C,Gumus E,Pinkard O,Miranda HC,Johnson K,Sweet TJ,Ji P,Lin A,Coller J,Philippidou P,Wagner EJ,Schaffer AE
Wed Apr 20 00:00:00 EDT 2022
Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration.
Neuron
LaForce GR,Farr JS,Liu J,Akesson C,Gumus E,Pinkard O,Miranda HC,Johnson K,Sweet TJ,Ji P,Lin A,Coller J,Philippidou P,Wagner EJ,Schaffer AE
Wed Apr 20 00:00:00 EDT 2022
Pyk2 suppresses contextual fear memory in an autophosphorylation-independent manner.
Journal of molecular cell biology
Zheng J,Suo L,Zhou Y,Jia L,Li J,Kuang Y,Cui D,Zhang X,Wu Q
Fri Jan 21 00:00:00 EST 2022
Artemisinin and Its Derivate Alleviate Pulmonary Hypertension and Vasoconstriction in Rodent Models.
Oxidative medicine and cellular longevity
Bao C,He Q,Wang H,Sun Y,Xu Y,Pan Y,Hu Y,Zheng S,Liang S,Luo A,Nahar T,Chen J,Tang H,Han Y
Tue Jun 28 00:00:00 EDT 2022
HGF Secreted by Mesenchymal Stromal Cells Promotes Primordial Follicle Activation by Increasing the Activity of the PI3K-AKT Signaling Pathway.
Stem cell reviews and reports
Mi X,Jiao W,Yang Y,Qin Y,Chen ZJ,Zhao S
Wed Jun 01 00:00:00 EDT 2022
HSP90 promotes radioresistance of cervical cancer cells via reducing FBXO6-mediated CD147 polyubiquitination.
Cancer science
Song Q,Wen J,Li W,Xue J,Zhang Y,Liu H,Han J,Ning T,Lu Z
Fri Apr 01 00:00:00 EDT 2022
The Apoptotic Resistance of BRCA1-Deficient Ovarian Cancer Cells is Mediated by cAMP.
Frontiers in cell and developmental biology
Yue W,Ma J,Xiao Y,Wang P,Gu X,Xie B,Li M
Sat Jul 16 00:00:00 EDT 2022
Prognostic Lnc-S100B-2 Affects Cell Apoptosis and Microenvironment of Colorectal Cancer through MLLT10 Signaling.
Journal of oncology
Yi J,Peng F,Zhao J,Gong X
Tue Feb 08 00:00:00 EST 2022
Long Noncoding RNA ENSG00000254693 Promotes Diabetic Kidney Disease via Interacting with HuR.
Journal of diabetes research
Yu Q,Lin J,Ma Q,Li Y,Wang Q,Chen H,Liu Y,Liu B
Tue May 03 00:00:00 EDT 2022
Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds.
International wound journal
Jiang M,Yakupu A,Guan H,Dong J,Liu Y,Song F,Tang J,Tian M,Niu Y,Lu S
Sat Jan 01 00:00:00 EST 2022
Hepatic RACK1 deficiency protects against fulminant hepatitis through myeloid-derived suppressor cells.
Theranostics
Liu G,Wang Q,Deng L,Huang X,Yang G,Cheng Q,Guo T,Guo L,Niu C,Yang X,Dong J,Zhang J
Thu Apr 21 00:00:00 EDT 2022
Sodium butyrate alleviates pre-eclampsia in pregnant rats by improving the gut microbiota and short-chain fatty acid metabolites production.
Journal of applied microbiology
Yong W,Zhao Y,Jiang X,Li P
Tue Feb 01 00:00:00 EST 2022
4EBP1 senses extracellular glucose deprivation and initiates cell death signaling in lung cancer.
Cell death & disease
Wang Y,Lei J,Zhang S,Wang X,Jin J,Liu Y,Gan M,Yuan Y,Sun L,Li X,Han T,Wang JB
Tue Dec 27 00:00:00 EST 2022
The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice.
European journal of immunology
Christgen S,Place DE,Zheng M,Briard B,Yamamoto M,Kanneganti TD
Tue Feb 01 00:00:00 EST 2022
HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability.
Neoplasma
Wang R,Hua L,Ma P,Song Y,Min J,Guo Y,Yang C,Li J,Su H
Thu Sep 01 00:00:00 EDT 2022
Mitochondrial Calcium-Triggered Oxidative Stress and Developmental Defects in Dopaminergic Neurons Differentiated from Deciduous Teeth-Derived Dental Pulp Stem Cells with MFF Insufficiency.
Antioxidants (Basel, Switzerland)
Sun X,Dong S,Kato H,Kong J,Ito Y,Hirofuji Y,Sato H,Kato TA,Sakai Y,Ohga S,Fukumoto S,Masuda K
Wed Jul 13 00:00:00 EDT 2022
CAV1 alleviated CaOx stones formation via suppressing autophagy-dependent ferroptosis.
PeerJ
Yang Y,Hong S,Lu Y,Wang Q,Wang S,Xun Y
Wed Jan 18 00:00:00 EST 2023
Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wuniqiemu T,Teng F,Qin J,Lv Y,Nabijan M,Luo Q,Zhou Y,Cui J,Yi L,Tang W,Zhu X,Wang S,Abduwaki M,Nurahmat M,Wei Y,Dong JC
Thu Sep 01 00:00:00 EDT 2022
Coxsackievirus B3 infection induces glycolysis to facilitate viral replication.
Frontiers in microbiology
Qian Y,Yang Y,Qing W,Li C,Kong M,Kang Z,Zuo Y,Wu J,Yu M,Yang Z
Tue Dec 27 00:00:00 EST 2022
Silencing TXNIP ameliorates high uric acid-induced insulin resistance via the IRS2/AKT and Nrf2/HO-1 pathways in macrophages.
Free radical biology & medicine
Yu W,Chen C,Zhuang W,Wang W,Liu W,Zhao H,Lv J,Xie D,Wang Q,He F,Xu C,Chen B,Yamamoto T,Koyama H,Cheng J
Sat Jan 01 00:00:00 EST 2022
SLC38A6, regulated by EP300-mediated modifications of H3K27ac, promotes cell proliferation, glutamine metabolism and mitochondrial respiration in hepatocellular carcinoma.
Carcinogenesis
Huang L,Li L,Cheng B,Xing T
Sat Oct 22 00:00:00 EDT 2022
3-Arylcoumarin inhibits vascular calcification by inhibiting the generation of AGEs and anti-oxidative stress.
Journal of enzyme inhibition and medicinal chemistry
Li Y,Pan Y,Wang L,Wang X,Chu H,Li Y,Mu Y,Sun J
Thu Dec 01 00:00:00 EST 2022
Anti-inflammatory Properties of the Alpha-Melanocyte-Stimulating Hormone in Models of Granulomatous Inflammation.
Lung
Shahraki AH,Tian R,Zhang C,Fregien NL,Bejarano P,Mirsaeidi M
Mon Aug 01 00:00:00 EDT 2022
Androgen receptor suppresses β-adrenoceptor-mediated CREB activation and thermogenesis in brown adipose tissue of male mice.
The Journal of biological chemistry
Harada N,Kubo K,Onishi T,Kitakaze T,Goto T,Inui H,Yamaji R
Thu Dec 01 00:00:00 EST 2022
Novel stress granule-like structures are induced via a paracrine mechanism during viral infection.
Journal of cell science
Iadevaia V,Burke JM,Eke L,Moller-Levet C,Parker R,Locker N
Tue Feb 15 00:00:00 EST 2022
Activation of PGC-1α via isoliquiritigenin-induced downregulation of miR-138-5p alleviates nonalcoholic fatty liver disease.
Phytotherapy research : PTR
Wang L,Wang X,Kong L,Li Y,Huang K,Wu J,Wang C,Sun H,Sun P,Gu J,Luo H,Liu K,Meng Q
Tue Feb 01 00:00:00 EST 2022
RAB27A promotes the proliferation and invasion of colorectal cancer cells.
Scientific reports
Li Q,Zhao H,Dong W,Guan N,Hu Y,Zeng Z,Zhang H,Zhang F,Li Q,Yang J,Xiao W
Sat Nov 12 00:00:00 EST 2022
Bicyclol alleviates high-fat diet-induced hepatic ER stress- and autophagy-associated non-alcoholic fatty liver disease/non-alcoholic steatohepatitis in mice.
Drug development and industrial pharmacy
Jia S,Jin L,Cheng X,Wu J,Yao X,Shao J,Zhang C,Cen D,Cheng B,Wang J,Chen L,Yao X
Wed Jun 01 00:00:00 EDT 2022
A Mechanistic Exploratory Study on the Therapeutic Efficacy of Astragaloside IV Against Diabetic Retinopathy Revealed by Network Pharmacology.
Frontiers in pharmacology
Zhao ZH,Xu M,Fu C,Huang Y,Wang TH,Zuo ZF,Liu XZ
Sat Jul 16 00:00:00 EDT 2022
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shi Y,Chen J,Li S,Wu Y,Yu C,Ni L,Xiao J,Shao Z,Zhu H,Wang J,Wang X,Zhang X
Fri Apr 01 00:00:00 EDT 2022
Upregulation of SQLE Contributes to Poor Survival in Head and Neck Squamous Cell Carcinoma.
International journal of biological sciences
Li J,Yang T,Wang Q,Li Y,Wu H,Zhang M,Qi H,Zhang H,Li J
Tue Jul 12 00:00:00 EDT 2022
Promoting Effect of L-Fucose on the Regeneration of Intestinal Stem Cells through AHR/IL-22 Pathway of Intestinal Lamina Propria Monocytes.
Nutrients
Tan C,Hong G,Wang Z,Duan C,Hou L,Wu J,Qian W,Han C,Hou X
Sat Nov 12 00:00:00 EST 2022
KLF16 inhibits PEDV replication by activating the type I IFN signaling pathway.
Veterinary microbiology
Dong S,Kong N,Shen H,Li Y,Qin W,Zhai H,Zhai X,Yang X,Ye C,Ye M,Liu C,Yu L,Zheng H,Tong W,Yu H,Zhang W,Tong G,Shan T
Tue Nov 01 00:00:00 EDT 2022
Network pharmacology analysis and experimental validation to explore the mechanism of Shenlian extract on myocardial ischemia.
Journal of ethnopharmacology
Li JJ,Wang CM,Wang YJ,Yang Q,Cai WY,Li YJ,Song M,Zang YL,Cui XH,Li Q,Chen Y,Weng XG,Zhu XX
Sun Apr 24 00:00:00 EDT 2022
Cystathionine-β-synthase (CBS)/H2S system promotes lymph node metastasis of esophageal squamous cell carcinoma (ESCC) by activating SIRT1.
Carcinogenesis
Liu Y,Pan L,Li Y,Deng Y,Han X,Fu H,Wang T
Thu May 19 00:00:00 EDT 2022
Asiatic Acid Attenuates Inflammation Induced by Salmonella via Upregulating LncRNA TVX1 in Microglia.
International journal of molecular sciences
Zou W,Zhang J,Zhang K,Peng Z,Xin R,Wang L,Li J
Mon Sep 19 00:00:00 EDT 2022
Paclitaxel-based supramolecular hydrogel loaded with mifepristone for the inhibition of breast cancer metastasis.
Cancer science
Zhao CC,Zhang CG,Sun X,Guo Q,Liu J,Liu Y,Hao YN,Feng G,Yang L,Liu H,Liu J
Tue Feb 01 00:00:00 EST 2022
High-circulating gut microbiota-dependent metabolite trimethylamine N-oxide is associated with poor prognosis in pulmonary arterial hypertension.
European heart journal open
Yang Y,Zeng Q,Gao J,Yang B,Zhou J,Li K,Li L,Wang A,Li X,Liu Z,Luo Q,Zhao Z,Liu B,Xue J,Jiang X,Konerman MC,Zheng L,Xiong C
Thu Sep 01 00:00:00 EDT 2022
Periostin promotes nucleus pulposus cells apoptosis by activating the Wnt/β-catenin signaling pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhu D,Wang Z,Zhang G,Ma C,Qiu X,Wang Y,Liu M,Guo X,Chen H,Deng Q,Kang X
Fri Jul 01 00:00:00 EDT 2022
Cisplatin-Induced Anorexia and Pica Behavior in Rats Enhanced by Chronic Stress Pretreatment.
Frontiers in pharmacology
Guo Z,Duan J,Chen Y,Cai W,Yang C,Yang Z,Liu X,Xu F
Tue Aug 02 00:00:00 EDT 2022
MiR-153 downregulation alleviates PTSD-like behaviors and reduces cell apoptosis by upregulating the Sigma-1 receptor in the hippocampus of rats exposed to single-prolonged stress.
Experimental neurology
Chen YL,Tong L,Chen Y,Fu CH,Peng JB,Ji LL
Wed Jun 01 00:00:00 EDT 2022
BMP4 Exerts Anti-Neurogenic Effect via Inducing Id3 during Aging.
Biomedicines
Li T,Liu H,Jiang D,Yang K,Shen J,Feng H,Wang S,Zhang Y,Wang Y,Tang TS
Tue May 17 00:00:00 EDT 2022
Neuroglobin expression and function in the temporal cortex of bilirubin encephalopathy rats.
Anatomical record (Hoboken, N.J. : 2007)
Hu JH,Fan P,Zhang LR,Chen CY,Xu J,Huang J,Lu WT,Zhu SJ,Qiu GP,Xu SY,Ran JH,Gan SW
Tue Feb 01 00:00:00 EST 2022
Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium.
Oxidative medicine and cellular longevity
Huang Q,Peng M,Gu Y,Wu J,Zhan Y,Deng Z,Chen S,Yang R,Chen J,Xie J
Fri Dec 30 00:00:00 EST 2022
Orally Administered Ginkgolide C Attenuates DSS-Induced Colitis by Maintaining Gut Barrier Integrity, Inhibiting Inflammatory Responses, and Regulating Intestinal Flora.
Journal of agricultural and food chemistry
Xu D,Zhuang L,Gao S,Ma H,Cheng J,Liu J,Liu D,Fu S,Hu G
Wed Nov 23 00:00:00 EST 2022
Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy.
Brain sciences
Xin Y,Wang J,Chu T,Zhou Y,Liu C,Xu A
Sat Dec 17 00:00:00 EST 2022
Occludin facilitates tumour angiogenesis in bladder cancer by regulating IL8/STAT3 through STAT4.
Journal of cellular and molecular medicine
Yang F,Liu XQ,He JZ,Xian SP,Yang PF,Mai ZY,Li M,Liu Y,Zhang XD
Fri Apr 01 00:00:00 EDT 2022
Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis.
Journal of immunology research
Lin D,Zhang M,Luo C,Wei P,Cui K,Chen Z
Tue Jun 28 00:00:00 EDT 2022
Melatonin Alleviates Liver Fibrosis by Inhibiting Autophagy.
Current medical science
Jie L,Hong RT,Zhang YJ,Sha LL,Chen W,Ren XF
Wed Jun 01 00:00:00 EDT 2022
Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer's disease.
Cell metabolism
Pan RY,He L,Zhang J,Liu X,Liao Y,Gao J,Liao Y,Yan Y,Li Q,Zhou X,Cheng J,Xing Q,Guan F,Zhang J,Sun L,Yuan Z
Tue Apr 05 00:00:00 EDT 2022
Post-Injury Buprenorphine Administration Is Associated with Long-Term Region-Specific Glial Alterations in Rats.
Pharmaceutics
Ryu J,Jeizan P,Ahmed S,Ehsan S,Jose J,Regan S,Gorse K,Kelliher C,Lafrenaye A
Wed Sep 28 00:00:00 EDT 2022
Circ_0060731 mediated miR-21-5p-PDCD4/ESR1 pathway to induce apoptosis of placental trophoblasts in intrahepatic cholestasis of pregnancy.
Tissue & cell
Feng F,Lei L,Liao J,Huang X,Shao Y
Wed Jun 01 00:00:00 EDT 2022
Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis.
Molecular medicine (Cambridge, Mass.)
Xiao J,Zeng W,Zhang P,Zhou Y,Fang Q
Tue Sep 06 00:00:00 EDT 2022
Identification of Biomarkers Related to Regulatory T Cell Infiltration in Oral Squamous Cell Carcinoma Based on Integrated Bioinformatics Analysis.
International journal of general medicine
Wang C,Chen Z,Yang X,Zhang W,Zhou J,Zhang H,Ding X,Ye J,Wu H,Wu Y,Zheng Y,Song X
Fri Mar 11 00:00:00 EST 2022
Hsp70 Inhibits the Replication of Fowl Adenovirus Serotype 4 by Suppressing Viral Hexon with the Assistance of DnaJC7.
Journal of virology
Cao J,Liu S,Liu M,Wang S,Bi Z,Fan W,Shi Z,Song S,Yan L
Wed Aug 10 00:00:00 EDT 2022
Protein-protein interactions between RUNX3 and ZEB1 in chronic lung injury induced by methamphetamine abuse.
Frontiers in pharmacology
Bao N,Cheng L,Wang Y,Peng Z,Wang Z,Chen S
Sat Dec 10 00:00:00 EST 2022
Sleeve gastrectomy improves lipid dysmetabolism by downregulating the USP20-HSPA2 axis in diet-induced obese mice.
Frontiers in endocrinology
Zhang W,Shi B,Li S,Liu Z,Li S,Dong S,Cheng Y,Zhu J,Zhang G,Zhong M
Tue Jan 17 00:00:00 EST 2023
Inhibition of KIF23 Alleviates IPAH by Targeting Pyroptosis and Proliferation of PASMCs.
International journal of molecular sciences
Wu Z,Zhou G,Wang H,Yao P
Mon Apr 18 00:00:00 EDT 2022
Nicotinamide mononucleotide supplementation protects the intestinal function in aging mice and D-galactose induced senescent cells.
Food & function
Ru M,Wang W,Zhai Z,Wang R,Li Y,Liang J,Kothari D,Niu K,Wu X
Mon Jul 18 00:00:00 EDT 2022
Identification of a small-molecule RPL11 mimetic that inhibits tumor growth by targeting MDM2-p53 pathway.
Molecular medicine (Cambridge, Mass.)
Wang B,Gao J,Zhao Z,Zhong X,Cui H,Hou H,Zhang Y,Zheng J,Di J,Liu Y
Wed Sep 07 00:00:00 EDT 2022
Nodakenin attenuates cartilage degradation and inflammatory responses in a mice model of knee osteoarthritis by regulating mitochondrial Drp1/ROS/NLRP3 axis.
International immunopharmacology
Yi N,Mi Y,Xu X,Li N,Chen B,Yan K,Tan K,Zhang B,Wang L,Kuang G,Lu M
Thu Dec 01 00:00:00 EST 2022
Neuroprotection of chicoric acid in a mouse model of Parkinson's disease involves gut microbiota and TLR4 signaling pathway.
Food & function
Wang N,Feng BN,Hu B,Cheng YL,Guo YH,Qian H
Mon Feb 21 00:00:00 EST 2022
Systemic gene therapy for methylmalonic acidemia using the novel adeno-associated viral vector 44.9.
Molecular therapy. Methods & clinical development
Chandler RJ,Di Pasquale G,Sloan JL,McCoy S,Hubbard BT,Kilts TM,Manoli I,Chiorini JA,Venditti CP
Thu Dec 08 00:00:00 EST 2022
LATS1 is a central signal transmitter for achieving full type-I interferon activity.
Science advances
Zuo Y,He J,Liu S,Xu Y,Liu J,Qiao C,Zang L,Sun W,Yuan Y,Zhang H,Chen X,Jin L,Miao Y,Huang F,Ren T,Wang J,Qian F,Zhu C,Zhang W,Liu Y,Xu G,Ma F,Zheng H
Fri Apr 08 00:00:00 EDT 2022
Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and intestinal flora.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Hao M,Ding C,Peng X,Chen H,Dong L,Zhang Y,Chen X,Liu W,Luo Y
Sat Oct 01 00:00:00 EDT 2022
Annexin A2 regulates Mycoplasma bovis adhesion and invasion to embryo bovine lung cells affecting molecular expression essential to inflammatory response.
Frontiers in immunology
Zhang H,Lu D,Zhang Y,Zhao G,Raheem A,Chen Y,Chen X,Hu C,Chen H,Yang L,Guo A
Wed Sep 28 00:00:00 EDT 2022
A single N6-methyladenosine site regulates lncRNA HOTAIR function in breast cancer cells.
PLoS biology
Porman AM,Roberts JT,Duncan ED,Chrupcala ML,Levine AA,Kennedy MA,Williams MM,Richer JK,Johnson AM
Tue Nov 01 00:00:00 EDT 2022
Preventive Effects of Ilex Cornuta Aqueous Extract on High-Fat Diet-Induced Fatty Liver of Mice.
Evidence-based complementary and alternative medicine : eCAM
Liu M,Jia H,He Y,Huan Y,Kong Z,Xu N,Cao X,Duan Y,Li Z,Yang L,Wei WP,Wang L,Li L
Sat Jul 16 00:00:00 EDT 2022
Integrative network analysis of circular RNAs reveals regulatory mechanisms for hepatic specification of human iPSC-derived endoderm.
Stem cell research & therapy
Bai F,Duan J,Yang D,Lai X,Zhu X,He X,Hu A
Thu Sep 08 00:00:00 EDT 2022
Construction and validation of a prognostic model with RNA binding protein-related mRNAs for the HBV-related hepatocellular carcinoma patients.
Frontiers in oncology
Xu S,Liu H,Tian R,Xie J,Chen S,Luo J,Zhu H,Wang Y,Li Z
Tue Oct 11 00:00:00 EDT 2022
Ornithine α-Ketoglutarate Alleviates Inflammation via Regulating Ileal Mucosa Microbiota and Metabolites in Enterotoxigenic Escherichia coli-Infected Pigs.
Frontiers in nutrition
Li Y,Bao X,Yang F,Tian J,Su W,Yin J,Yao K,Li T,Yin Y
Sat Jul 16 00:00:00 EDT 2022
M2 microglia-derived extracellular vesicles promote white matter repair and functional recovery via miR-23a-5p after cerebral ischemia in mice.
Theranostics
Li Y,Liu Z,Song Y,Pan JJ,Jiang Y,Shi X,Liu C,Ma Y,Luo L,Mamtilahun M,Shi Z,Khan H,Xie Q,Wang Y,Tang Y,Zhang Z,Yang GY
Tue May 17 00:00:00 EDT 2022
Gankyrin modulated non-small cell lung cancer progression via glycolysis metabolism in a YAP1-dependent manner.
Cell death discovery
Yu T,Liu Y,Xue J,Sun X,Zhu D,Ma L,Guo Y,Jin T,Cao H,Chen Y,Zhu T,Li X,Liang H,Du Z,Shan H
Sat Jul 09 00:00:00 EDT 2022
Extracellular vimentin is expressed at the rear of activated macrophage-like cells: Potential role in enhancement of migration and phagocytosis.
Frontiers in cell and developmental biology
Thalla DG,Rajwar AC,Laurent AM,Becher JE,Kainka L,Lautenschläger F
Fri Aug 05 00:00:00 EDT 2022
Pan-Cancer Analysis of the Immunological Role of PDIA5: A Potential Target for Immunotherapy.
Frontiers in immunology
Chen Y,He J,Chen R,Wang Z,Dai Z,Liang X,Wu W,Luo P,Zhang J,Peng Y,Zhang N,Liu Z,Zhang L,Zhang H,Cheng Q
Fri Aug 26 00:00:00 EDT 2022
Targeting Cell Membranes, Depleting ROS by Dithiane and Thioketal-Containing Polymers with Pendant Cholesterols Delivering Necrostatin-1 for Glaucoma Treatment.
ACS nano
Rong R,Zhou X,Liang G,Li H,You M,Liang Z,Zeng Z,Xiao H,Ji D,Xia X
Tue Dec 27 00:00:00 EST 2022
Vibrio harveyi infections induce production of proinflammatory cytokines in murine peritoneal macrophages via activation of p38 MAPK and NF-κB pathways, but reversed by PI3K/AKT pathways.
Developmental and comparative immunology
Yu G,Yu H,Yang Q,Wang J,Fan H,Liu G,Wang L,Bello BK,Zhao P,Zhang H,Dong J
Tue Feb 01 00:00:00 EST 2022
Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1.
Acta pharmacologica Sinica
Li JW,Wang RL,Xu J,Sun KY,Jiang HM,Sun ZY,Lv ZY,Xu XQ,Wu R,Guo H,Jiang Q,Shi DQ
Tue Feb 01 00:00:00 EST 2022
27-hydroxycholesterol linked high cholesterol diet to lung adenocarcinoma metastasis.
Oncogene
Li X,Chen H,Zhang L,Chen L,Wei W,Gao S,Xue Q,Li Y,Wang B,Li J,Gao Y,Lin Y
Sun May 01 00:00:00 EDT 2022
Cordycepin prevents and ameliorates experimental autoimmune encephalomyelitis by inhibiting leukocyte infiltration and reducing neuroinflammation.
Biochemical pharmacology
Song YC,Liu CT,Lee HJ,Yen HR
Tue Mar 01 00:00:00 EST 2022
TARDBP Inhibits Porcine Epidemic Diarrhea Virus Replication through Degrading Viral Nucleocapsid Protein and Activating Type I Interferon Signaling.
Journal of virology
Dong S,Kong N,Zhang Y,Li Y,Sun D,Qin W,Zhai H,Zhai X,Yang X,Ye C,Ye M,Liu C,Yu L,Zheng H,Tong W,Yu H,Zhang W,Tong G,Shan T
Wed May 25 00:00:00 EDT 2022
Dabie bandavirus Nonstructural Protein Interacts with Actin to Induce F-Actin Rearrangement and Inhibit Viral Adsorption and Entry.
Journal of virology
Liu H,Liu S,Liu Z,Gao X,Xu L,Huang M,Su Y,Wang Z,Wang T
Wed Jul 27 00:00:00 EDT 2022
Isorhamnetin protects zearalenone-induced damage via the PI3K/Akt signaling pathway in porcine ovarian granulosa cells.
Animal nutrition (Zhongguo xu mu shou yi xue hui)
Li X,Chen H,Zhang Z,Duan J,Hua R,Li X,Yang L,Cheng J,Li Q
Thu Dec 01 00:00:00 EST 2022
Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Nutrients
Shi JZ,Zheng XM,Zhou YF,Yun LY,Luo DM,Hao JJ,Liu PF,Zhang WK,Xu JK,Yan Y,Xie XM,He YY,Pang XB
Wed Aug 03 00:00:00 EDT 2022
Neuregulin-1 regulates the conversion of M1/M2 microglia phenotype via ErbB4-dependent inhibition of the NF-κB pathway.
Molecular biology reports
Ma Y,Fan P,Zhao R,Zhang Y,Wang X,Cui W
Sun May 01 00:00:00 EDT 2022
Clinical identification of expressed proteins in adrenal medullary hyperplasia detected with hypertension.
Frontiers in endocrinology
Ma H,Wang K,Lai B,Zhang X,Lv Y,Li R
Mon Jan 02 00:00:00 EST 2023
KIF17 maintains the epithelial phenotype of breast cancer cells and curbs tumour metastasis.
Cancer letters
Li T,Zhai D,Zhang M,Ye R,Kuang X,Shao N,Bi J,Lin Y
Tue Nov 01 00:00:00 EDT 2022
Effects of growth hormone/estrogen/androgen on COVID-19-type proinflammatory responses in normal human lung epithelial BEAS-2B cells.
BMC molecular and cell biology
Zhu Z,Zhao Z,Chen X,Chu Z,He Y,Tan Y,Zhou J,Tang C
Thu Sep 29 00:00:00 EDT 2022
Tetrandrine Ameliorates Traumatic Brain Injury by Regulating Autophagy to Reduce Ferroptosis.
Neurochemical research
Liu H,He S,Wang J,Li C,Liao Y,Zou Q,Chen R
Wed Jun 01 00:00:00 EDT 2022
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
Bioorganic chemistry
Li T,Chen Y,Tan P,Shi H,Huang Z,Cai T,Cheng Y,Du Y,Fu W
Sun May 01 00:00:00 EDT 2022
Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity.
Acta pharmacologica Sinica
He JY,Hong Q,Chen BX,Cui SY,Liu R,Cai GY,Guo J,Chen XM
Tue Feb 01 00:00:00 EST 2022
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
Cell death & disease
Wang R,Wen P,Yang G,Feng Y,Mi Y,Wang X,Zhu S,Chen YQ
Tue Jul 19 00:00:00 EDT 2022
Mammalian PERIOD2 regulates H2A.Z incorporation in chromatin to orchestrate circadian negative feedback.
Nature structural & molecular biology
Tartour K,Andriani F,Folco EG,Letkova D,Schneider R,Saidi I,Sato T,Welz PS,Benitah SA,Allier C,Padmanabhan K
Wed Jun 01 00:00:00 EDT 2022
The Mechanism of Lipopolysaccharide Escaping the Intestinal Barrier in Megalobrama amblycephala Fed a High-Fat Diet.
Frontiers in nutrition
Dai YJ,Liu WB,Abasubong KP,Zhang DD,Li XF,Xiao K,Wang X,Jiang GZ
Sat Jul 16 00:00:00 EDT 2022
Oxidative stress and Cx43-mediated apoptosis are involved in PFOS-induced nephrotoxicity.
Toxicology
Tang L,Yu J,Zhuge S,Chen H,Zhang L,Jiang G
Mon Aug 01 00:00:00 EDT 2022
Umbilical Cord Mesenchymal Stem Cells Ameliorate Kidney Injury in MRL/Ipr Mice Through the TGF-β1 Pathway.
Frontiers in cell and developmental biology
Huang C,Meng M,Li S,Liu S,Li L,Su Y,Gao H,He S,Zhao Y,Zhang M,Hou Z,Wang W,Wang X
Sat Jul 16 00:00:00 EDT 2022
Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels.
Phytotherapy research : PTR
Cheng L,Shi L,He C,Wang C,Lv Y,Li H,An Y,Dai H,Duan Y,Zhang H,Huang Y,Fu W,Meng Y,Zhao B
Wed Jun 01 00:00:00 EDT 2022
Akebia Saponin D Inhibits the Inflammatory Reaction by Inhibiting the IL-6-STAT3-DNMT3b Axis and Activating the Nrf2 Pathway.
Molecules (Basel, Switzerland)
Luo JF,Zhou H,Lio CK
Thu Sep 22 00:00:00 EDT 2022
Role of TGF-β1 in Fluoride-Treated Osteoblasts at Different Stages.
Biological trace element research
Jiang N,Xu W,Zhang Z,Jin H,Yang Y,Zhang J,Xu H
Tue Feb 01 00:00:00 EST 2022
Incomplete autophagy promotes the proliferation of Mycoplasma hyopneumoniae through the JNK and Akt pathways in porcine alveolar macrophages.
Veterinary research
Wen Y,Chen Z,Tian Y,Yang M,Dong Q,Yang Y,Ding H
Thu Aug 04 00:00:00 EDT 2022
MAB21L1 promotes survival of lens epithelial cells through control of αB-crystallin and ATR/CHK1/p53 pathway.
Aging
Xiao Y,Xiang JW,Gao Q,Bai YY,Huang ZX,Hu XH,Wang L,Li DW
Wed Aug 10 00:00:00 EDT 2022
Synchronous Disintegration of Ferroptosis Defense Axis via Engineered Exosome-Conjugated Magnetic Nanoparticles for Glioblastoma Therapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Li B,Chen X,Qiu W,Zhao R,Duan J,Zhang S,Pan Z,Zhao S,Guo Q,Qi Y,Wang W,Deng L,Ni S,Sang Y,Xue H,Liu H,Li G
Wed Jun 01 00:00:00 EDT 2022
Effect of Xiongmatang Extract on Behavioral and TRPV1-CGRP/CGRP-R Pathway in Rats With Migraine.
Frontiers in pharmacology
Liu D,Chang L,Wang J,Zhu Q,Jiang N,Azhar M,Ahmed A,Zeng G
Fri Apr 01 00:00:00 EDT 2022
PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.
Cell death & disease
Zhang T,Wang Y,Yu H,Zhang T,Guo L,Xu J,Wei X,Wang N,Wu Y,Wang X,Huang L
Thu Jan 20 00:00:00 EST 2022
PGK1 represses autophagy-mediated cell death to promote the proliferation of liver cancer cells by phosphorylating PRAS40.
Cell death & disease
Zhang T,Wang Y,Yu H,Zhang T,Guo L,Xu J,Wei X,Wang N,Wu Y,Wang X,Huang L
Thu Jan 20 00:00:00 EST 2022
Artemisia sphaerocephala Krasch polysaccharide promotes adipose thermogenesis and decreases obesity by shaping the gut microbiota.
Food & function
Zeng X,Ren D,Li D,Du H,Yang X
Mon Oct 17 00:00:00 EDT 2022
Implications of miR-148a-3p/p35/PTEN signaling in tau hyperphosphorylation and autoregulatory feedforward of Akt/CREB in Alzheimer's disease.
Molecular therapy. Nucleic acids
Zeng L,Jiang H,Ashraf GM,Liu J,Wang L,Zhao K,Liu M,Li Z,Liu R
Tue Mar 08 00:00:00 EST 2022
Targeted Disruption of a Proximal Tubule-Specific TMEM174 Gene in Mice Causes Hyperphosphatemia and Vascular Calcification.
Journal of the American Society of Nephrology : JASN
Miyazaki-Anzai S,Keenan AL,Blaine J,Miyazaki M
Mon Aug 01 00:00:00 EDT 2022
Fabrication of SA/Gel/C scaffold with 3D bioprinting to generate micro-nano porosity structure for skin wound healing: a detailed animal in vivo study.
Cell regeneration (London, England)
Niu C,Wang L,Ji D,Ren M,Ke D,Fu Q,Zhang K,Yang X
Sun May 01 00:00:00 EDT 2022
CIDEA Regulates De Novo Fatty Acid Synthesis in Bovine Mammary Epithelial Cells by Targeting the AMPK/PPARγ Axis and Regulating SREBP1.
Journal of agricultural and food chemistry
Cheng J,Xu D,Chen L,Guo W,Hu G,Liu J,Fu S
Wed Sep 14 00:00:00 EDT 2022
CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.
American journal of respiratory and critical care medicine
Cui H,Xie N,Banerjee S,Dey T,Liu RM,Antony VB,Sanders YY,Adams TS,Gomez JL,Thannickal VJ,Kaminski N,Liu G
Mon Aug 15 00:00:00 EDT 2022
Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics.
Nature metabolism
Liu Q,Zhu F,Liu X,Lu Y,Yao K,Tian N,Tong L,Figge DA,Wang X,Han Y,Li Y,Zhu Y,Hu L,Ji Y,Xu N,Li D,Gu X,Liang R,Gan G,Wu L,Zhang P,Xu T,Hu H,Hu Z,Xu H,Ye D,Yang H,Li B,Tong X
Sun May 01 00:00:00 EDT 2022
GDF15 negatively regulates RGS16 to impair hepatic lipid metabolism in male mice offspring conceived by in vitro fertilization.
American journal of translational research
Liu J,Zhu Y,Zhu D,Shi Y,Lu L,Li W,Li L,Zhou X,Zhang P,Yang H,Li M,Wang B,Sun M
Sat Nov 19 00:00:00 EST 2022
Transcriptome Analysis of Protection by Dendrobium Nobile Alkaloids (DNLA) against Chronic Alcoholic Liver Injury in Mice.
Biomedicines
Huang X,Yang S,Sun J,Li X,Zhou SY,Shi JS,Liu J,Wu Q
Thu Nov 03 00:00:00 EDT 2022
PINK1 deficiency in gastric cancer compromises mitophagy, promotes the Warburg effect, and facilitates M2 polarization of macrophages.
Cancer letters
Xu Y,Lu J,Tang Y,Xie W,Zhang H,Wang B,Zhang S,Hou W,Zou C,Jiang P,Zhang W
Thu Mar 31 00:00:00 EDT 2022
MiR-205-5p Functions as a Tumor Suppressor in Gastric Cancer Cells through Downregulating FAM84B.
Journal of oncology
Chen X,Zhang L,Geng J,Chen Z,Cui X
Sat Jul 16 00:00:00 EDT 2022
Empagliflozin Attenuates Obesity-Related Kidney Dysfunction and NLRP3 Inflammasome Activity Through the HO-1-Adiponectin Axis.
Frontiers in endocrinology
Ye T,Zhang J,Wu D,Shi J,Kuang Z,Ma Y,Xu Q,Chen B,Kan C,Sun X,Han F
Wed Jul 06 00:00:00 EDT 2022
β-Caryophyllene suppresses ferroptosis induced by cerebral ischemia reperfusion via activation of the NRF2/HO-1 signaling pathway in MCAO/R rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Hu Q,Zuo T,Deng L,Chen S,Yu W,Liu S,Liu J,Wang X,Fan X,Dong Z
Wed Jul 20 00:00:00 EDT 2022
The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.
International journal of molecular sciences
Cheng M,Yu H,Kong Q,Wang B,Shen L,Dong D,Sun L
Tue Jan 25 00:00:00 EST 2022
Cannabidiol prevents methamphetamine-induced neurotoxicity by modulating dopamine receptor D1-mediated calcium-dependent phosphorylation of methyl-CpG-binding protein 2.
Frontiers in pharmacology
Shen B,Zhang R,Yang G,Peng Y,Nie Q,Yu H,Dong W,Chen B,Song C,Tian Y,Qin L,Shu J,Hong S,Li L
Sat Sep 24 00:00:00 EDT 2022
Catalpol relieved angiotensin II-induced blood-brain barrier destruction via inhibiting the TLR4 pathway in brain endothelial cells.
Pharmaceutical biology
Xia Y,Lu YW,Hao RJ,Yu GR
Thu Dec 01 00:00:00 EST 2022
Total flavonoids from the dried root of Tetrastigma hemsleyanum Diels et Gilg inhibit colorectal cancer growth through PI3K/AKT/mTOR signaling pathway.
Phytotherapy research : PTR
Zhai Y,Sun J,Sun C,Zhao H,Li X,Yao J,Su J,Xu X,Xu X,Hu J,Daglia M,Han B,Kai G
Tue Nov 01 00:00:00 EDT 2022
Dasatinib suppresses atherosclerotic lesions by suppressing cholesterol uptake in a mouse model of hypercholesterolemia.
Journal of pharmacological sciences
Takaba M,Iwaki T,Arakawa T,Ono T,Maekawa Y,Umemura K
Fri Jul 01 00:00:00 EDT 2022
Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma.
Molecular metabolism
Chen X,Liu Q,Chen Y,Wang L,Yang R,Zhang W,Pan X,Zhang S,Chen C,Wu T,Xia J,Cheng B,Chen X,Ren X
Tue Nov 01 00:00:00 EDT 2022
Osthole inhibits the migration and invasion of highly metastatic breast cancer cells by suppressing ITGα3/ITGβ5 signaling.
Acta pharmacologica Sinica
Chen YQ,Song HY,Zhou ZY,Ma J,Luo ZY,Zhou Y,Wang JY,Liu S,Han XH
Wed Jun 01 00:00:00 EDT 2022
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Advanced healthcare materials
Guo S,Yao M,Zhang D,He Y,Chang R,Ren Y,Guan F
Tue Feb 01 00:00:00 EST 2022
Ginsenoside Rg1 Reduces Oxidative Stress Via Nrf2 Activation to Regulate Age-Related Mesenchymal Stem Cells Fate Switch Between Osteoblasts and Adipocytes.
Evidence-based complementary and alternative medicine : eCAM
Hou J,Wang L,Wang C,Ma R,Wang Z,Xiao H,Zeng D,Ling L,Wang Y
Sat Oct 22 00:00:00 EDT 2022
Glucosamine delays the progression of osteoporosis in senile mice by promoting osteoblast autophagy.
Nutrition & metabolism
Su W,Lv C,Huang L,Zheng X,Yang S
Tue Nov 08 00:00:00 EST 2022
Identification of active natural products that induce lysosomal biogenesis by lysosome-based screening and biological evaluation.
Heliyon
Ding X,Yang X,Zhao Y,Wang Y,Fei J,Niu Z,Dong X,Wang X,Liu B,Li H,Hao X,Zhao Y
Sat Oct 01 00:00:00 EDT 2022
Exosomal circRNA Scm-like with four malignant brain tumor domains 2 (circ-SFMBT2) enhances the docetaxel resistance of prostate cancer via the microRNA-136-5p/tribbles homolog 1 pathway.
Anti-cancer drugs
Tan X,Song X,Fan B,Li M,Zhang A,Pei L
Sat Oct 01 00:00:00 EDT 2022
Circular RNA circPTPRF promotes the progression of GBM via sponging miR-1208 to up-regulate YY1.
Cancer cell international
Zhou J,Wang C,Liu Y,Cui D,Wang Z,Jiang Y,Gao L
Thu Nov 17 00:00:00 EST 2022
Urolithin A promotes mitophagy and suppresses NLRP3 inflammasome activation in lipopolysaccharide-induced BV2 microglial cells and MPTP-induced Parkinson's disease model.
Neuropharmacology
Qiu J,Chen Y,Zhuo J,Zhang L,Liu J,Wang B,Sun D,Yu S,Lou H
Fri Apr 01 00:00:00 EDT 2022
XBP1s promotes the development of lung adenocarcinoma via the p‑JNK MAPK pathway.
International journal of molecular medicine
Jiang H,Jiang Q,He Y,Li X,Xu Y,Liu X
Tue Mar 01 00:00:00 EST 2022
BCAT1 promotes lung adenocarcinoma progression through enhanced mitochondrial function and NF-κB pathway activation.
Journal of Zhejiang University. Science. B
Yu M,Zhao Q,Li J,Xu F,Zhang Z,Liu Y,Dai L,Zhang B,Zhang J,Zhang J
Mon Sep 19 00:00:00 EDT 2022
Alleviating effects of selenium on fluoride-induced testosterone synthesis disorder and reproduction toxicity in rats.
Ecotoxicology and environmental safety
Zhao H,Zhu Y,Zhao Y,Wang T,Li H,Yang J,Cheng X,Wang J,Wang J
Thu Dec 01 00:00:00 EST 2022
miRNA-338-3p inhibits glioma cell proliferation and progression by targeting MYT1L.
Brain research bulletin
Yu Z,Liu Y,Li Y,Zhang J,Peng J,Gong J,Xia Y,Wang L
Tue Feb 01 00:00:00 EST 2022
Construction of Attenuated Strains for Red-Spotted Grouper Nervous Necrosis Virus (RGNNV) via Reverse Genetic System.
Viruses
Lei Y,Xiong Y,Tao D,Wang T,Chen T,Du X,Cao G,Tu J,Dai J
Sat Aug 06 00:00:00 EDT 2022
Tanshinone IIA alleviates NLRP3 inflammasome-mediated pyroptosis in Mycobacterium tuberculosis-(H37Ra-) infected macrophages by inhibiting endoplasmic reticulum stress.
Journal of ethnopharmacology
Li Y,Fu Y,Sun J,Shen J,Liu F,Ning B,Lu Z,Wei L,Jiang X
Mon Jan 10 00:00:00 EST 2022
Thiamine pretreatment improves endotoxemia-related liver injury and cholestatic complications by regulating galactose metabolism and inhibiting macrophage activation.
International immunopharmacology
Li T,Bai J,Du Y,Tan P,Zheng T,Chen Y,Cheng Y,Cai T,Huang M,Fu W,Wen J
Fri Jul 01 00:00:00 EDT 2022
Notch activation suppresses endothelial cell migration and sprouting via miR-223-3p targeting Fbxw7.
In vitro cellular & developmental biology. Animal
Wang R,Yang Z,Liang L,Feng X,Che B,Zhang X,Zheng Q,Yan X,Han H
Tue Feb 01 00:00:00 EST 2022
The amino acids of Autographa californica multiple nucleopolyhedrovirus P48 critical for the association with Ac93 are important for the nuclear egress of nucleocapsids and efficient formation of intranuclear microvesicles.
Virus research
Wang Y,He J,Mo M,Cai Q,Wu W,Yuan M,Yang K
Sat Jan 15 00:00:00 EST 2022
Genetic Inhibition of Plppr5 Aggravates Hypoxic-Ischemie-Induced Cortical Damage and Excitotoxic Phenotype.
Frontiers in neuroscience
Sun Y,Jin MF,Li L,Liu Y,Wang D,Ni H
Wed Apr 13 00:00:00 EDT 2022
Burdock (Arctium lappa L.) leaf flavonoids rich in morin and quercetin 3-O-rhamnoside ameliorate lipopolysaccharide-induced inflammation and oxidative stress in RAW264.7 cells.
Food science & nutrition
Cui J,Zong W,Zhao N,Yuan R
Mon Aug 01 00:00:00 EDT 2022
Docetaxel-resistant triple-negative breast cancer cell-derived exosomal lncRNA LINC00667 reduces the chemosensitivity of breast cancer cells to docetaxel via targeting miR-200b-3p/Bcl-2 axis.
European journal of histochemistry : EJH
Li J,Kang J,Liu W,Liu J,Pan G,Mao A,Zhang Q,Lu J,Ding J,Li H
Tue Oct 25 00:00:00 EDT 2022
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma.
Autophagy
Han T,Wang P,Wang Y,Xun W,Lei J,Wang T,Lu Z,Gan M,Zhang W,Yu B,Wang JB
Wed Jun 01 00:00:00 EDT 2022
YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway.
Journal of experimental & clinical cancer research : CR
Li W,Ye K,Li X,Liu X,Peng M,Chen F,Xiong W,Wang Y,Zhu L
Wed Aug 17 00:00:00 EDT 2022
Proteomic analysis reveals zinc-finger CCHC-type containing protein 3 as a factor inhibiting virus infection by promoting innate signaling.
Virus research
Chen X,Li Z,Wang S,Tong G,Chen K,Zhao Y
Sun Oct 02 00:00:00 EDT 2022
Effect of the Pulsed Electromagnetic Field Treatment in a Rat Model of Senile Osteoporosis In Vivo.
Bioelectromagnetics
Zhou J,Wang J,Qu M,Huang X,Yin L,Liao Y,Huang F,Ning P,Zhong P,Zeng Y
Sat Oct 01 00:00:00 EDT 2022
In Vivo Visualization of RNAi Efficiency Using a Pumilio/FBF Protein-Based Reporter.
Analytical chemistry
Shi X,Hu C,Jiang Y,Lei Z,Zhang C,Zhang B,Wang F
Tue Nov 08 00:00:00 EST 2022
Cancer stem cell regulated phenotypic plasticity protects metastasized cancer cells from ferroptosis.
Nature communications
Wu M,Zhang X,Zhang W,Chiou YS,Qian W,Liu X,Zhang M,Yan H,Li S,Li T,Han X,Qian P,Liu S,Pan Y,Lobie PE,Zhu T
Wed Mar 16 00:00:00 EDT 2022
Sodium houttuynia alleviates airway inflammation in asthmatic mice by regulating FoxP3/RORγT expression and reversing Treg/Th17 cell imbalance.
International immunopharmacology
Wang C,Huang CF,Li M
Tue Feb 01 00:00:00 EST 2022
Hyperglycemia Promotes Endothelial Cell Senescence through AQR/PLAU Signaling Axis.
International journal of molecular sciences
Wan Y,Liu Z,Wu A,Khan AH,Zhu Y,Ding S,Li X,Zhao Y,Dai X,Zhou J,Liu J,Li Y,Gong X,Liu M,Tian XL
Mon Mar 07 00:00:00 EST 2022
Role of Lysocardiolipin Acyltransferase in Cigarette Smoke-Induced Lung Epithelial Cell Mitochondrial ROS, Mitochondrial Dynamics, and Apoptosis.
Cell biochemistry and biophysics
Bandela M,Suryadevara V,Fu P,Reddy SP,Bikkavilli K,Huang LS,Dhavamani S,Subbaiah PV,Singla S,Dudek SM,Ware LB,Ramchandran R,Natarajan V
Tue Mar 01 00:00:00 EST 2022
Astragalus propinquus schischkin and Salvia miltiorrhiza bunge promote angiogenesis to treat myocardial ischemia via Ang-1/Tie-2/FAK pathway.
Frontiers in pharmacology
Zhang MX,Huang XY,Song Y,Xu WL,Li YL,Li C
Thu Feb 02 00:00:00 EST 2023
Genome-scale CRISPR-Cas9 screen reveals novel regulators of B7-H3 in tumor cells.
Journal for immunotherapy of cancer
Zhao S,Wang Y,Yang N,Mu M,Wu Z,Li H,Tang X,Zhong K,Zhang Z,Huang C,Cao T,Zheng M,Wang G,Nie C,Yang H,Guo G,Zhou L,Zheng X,Tong A
Wed Jun 01 00:00:00 EDT 2022
X-box binding protein 1: A new metabolic mediator and drug target of metformin?
Frontiers in pharmacology
Lou K,Sun P,Zhang C,Jiang Q,Pang S
Tue Nov 29 00:00:00 EST 2022
NCAPH is a prognostic biomarker and associated with immune infiltrates in lung adenocarcinoma.
Scientific reports
Li C,Meng J,Zhang T
Fri Jun 10 00:00:00 EDT 2022
LncRNA GAS5 regulates the Wnt/β-catenin pathway through the miR-18a-5p/AXIN2/GSK3β axis to inhibit the proliferation and migration of bladder cancer cells.
Carcinogenesis
Zhang Z,Liu T,Cheng C,Wang J,Wang C,Huang H,Li Y
Sat Dec 31 00:00:00 EST 2022
MALAT1 modulates alternative splicing by cooperating with the splicing factors PTBP1 and PSF.
Science advances
Miao H,Wu F,Li Y,Qin C,Zhao Y,Xie M,Dai H,Yao H,Cai H,Wang Q,Song X,Li L
Fri Dec 23 00:00:00 EST 2022
GRP75-driven, cell-cycle-dependent macropinocytosis of Tat/pDNA-Ca2+ nanoparticles underlies distinct gene therapy effect in ovarian cancer.
Journal of nanobiotechnology
Su L,Sun Z,Qi F,Su H,Qian L,Li J,Zuo L,Huang J,Yu Z,Li J,Chen Z,Zhang S
Wed Jul 20 00:00:00 EDT 2022
Ferroptosis as a mechanism of oligodendrocyte loss and demyelination in experimental autoimmune encephalomyelitis.
Journal of neuroimmunology
Li X,Chu Y,Ma R,Dou M,Li S,Song Y,Lv Y,Zhu L
Thu Dec 15 00:00:00 EST 2022
Inhibition of 8-oxoguanine DNA glycosylase (OGG1) expression suppresses polycystic ovarian syndrome via the NF-κB signaling pathway.
Reproductive biology
Xia J,Wu S,Wu G,Yang J
Thu Sep 01 00:00:00 EDT 2022
The OPG/RANKL/RANK system modulates calcification of common carotid artery in simulated microgravity rats by regulating NF-κB pathway.
Canadian journal of physiology and pharmacology
Liu H,Ru NY,Cai Y,Lyu Q,Guo CH,Zhou Y,Li SH,Cheng JH,Chang JR,Ma J,Su XL
Fri Apr 01 00:00:00 EDT 2022
Exploring the protective mechanisms of total tannins from Geum japonicum var. chinense F.Bolle in mice with hematopoietic dysfunction via the JAK2/STAT3/5 signaling pathway.
Journal of ethnopharmacology
Mu W,Ao J,Li Y,Zhang J,Duan C
Wed Oct 05 00:00:00 EDT 2022
Mitochondrial STAT3 exacerbates LPS-induced sepsis by driving CPT1a-mediated fatty acid oxidation.
Theranostics
Li R,Li X,Zhao J,Meng F,Yao C,Bao E,Sun N,Chen X,Cheng W,Hua H,Li X,Wang B,Wang H,Pan X,You H,Yang J,Ikezoe T
Thu Mar 10 00:00:00 EST 2022
ESR1 Regulates the Obesity- and Metabolism-Differential Gene MMAA to Inhibit the Occurrence and Development of Hepatocellular Carcinoma.
Frontiers in oncology
Zhang Y,Cheng J,Zhong C,Xia Q,Li Y,Chen P,Fan X,Mao Q,Lin H,Hong D
Sat Jul 16 00:00:00 EDT 2022
Connective tissue disease-related interstitial lung disease is alleviated by tripterine through inhibition of the PI3K/Akt, apoptosis, and TNF-α signalling pathways.
Frontiers in pharmacology
Zhu W,Wang Y,Liu C,Wu Y,Li Y,Wang Y
Fri Nov 25 00:00:00 EST 2022
Prefrontal GABAA(δ)R Promotes Fear Extinction through Enabling the Plastic Regulation of Neuronal Intrinsic Excitability.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Pan HQ,Liu XX,He Y,Zhou J,Liao CZ,You WJ,Jiang SY,Qin X,Chen WB,Fei EK,Zhang WH,Pan BX
Wed Jul 20 00:00:00 EDT 2022
Fucoidan ameliorates LPS-induced neuronal cell damage and cognitive impairment in mice.
International journal of biological macromolecules
Wang Y,Wang Q,Duan L,Li X,Yang W,Huang T,Kong M,Guan F,Ma S
Thu Dec 01 00:00:00 EST 2022
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression.
Nature cell biology
Huang D,Wang Y,Thompson JW,Yin T,Alexander PB,Qin D,Mudgal P,Wu H,Liang Y,Tan L,Pan C,Yuan L,Wan Y,Li QJ,Wang XF
Tue Feb 01 00:00:00 EST 2022
Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury.
Cell death & disease
Xie Q,Zhang M,Mao X,Xu M,Liu S,Shang D,Xu Y,Chen R,Guan Y,Huang X,Zent R,Pozzi A,Hao CM
Thu Dec 15 00:00:00 EST 2022
Photobiomodulation promotes repair following spinal cord injury by restoring neuronal mitochondrial bioenergetics via AMPK/PGC-1α/TFAM pathway.
Frontiers in pharmacology
Zhu Z,Wang X,Song Z,Zuo X,Ma Y,Zhang Z,Ju C,Liang Z,Li K,Hu X,Wang Z
Fri Sep 30 00:00:00 EDT 2022
Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants.
Journal of medicinal chemistry
Pan S,Zhang L,Luo X,Nan J,Yang W,Bin H,Li Y,Huang Q,Wang T,Pan Z,Mu B,Wang F,Tian C,Liu Y,Li L,Yang S
Thu Feb 10 00:00:00 EST 2022
Proto-oncogene FAM83A contributes to casein kinase 1-mediated mitochondrial maintenance and white adipocyte differentiation.
The Journal of biological chemistry
Huang K,Jia Z,Li H,Peng Y,Chen X,Luo N,Song T,Wang Y,Shi X,Kuang S,Yang G
Sat Oct 01 00:00:00 EDT 2022
Hsa_circ_0000345 inhibits cell proliferation, migration and invasion of nasopharyngeal carcinoma cells via miR-513a-3p/PTEN axis.
The journal of physiological sciences : JPS
Jiang C,Li H,Liu F,Shi L,Liu J,Li Y
Thu May 12 00:00:00 EDT 2022
IL-37 alleviates Coxsackievirus B3-induced viral myocarditis via inhibiting NLRP3 inflammasome-mediated pyroptosis.
Scientific reports
Sun L,Yuan H,Zhao G
Tue Nov 22 00:00:00 EST 2022
Luteolin ameliorates hypoxia-induced pulmonary hypertension via regulating HIF-2α-Arg-NO axis and PI3K-AKT-eNOS-NO signaling pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Ji L,Su S,Xin M,Zhang Z,Nan X,Li Z,Lu D
Thu Sep 01 00:00:00 EDT 2022
Effects of 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione on autophagy and the PI3K/AKT/mTOR signaling pathway in human cholangiocarcinoma QBC939 cells.
Journal of gastrointestinal oncology
He Y,Li Y,Liang T,Mo S,Liao Y,Chen Z,Zhao S,Ran Q,Han C,Hoa PTT
Wed Jun 01 00:00:00 EDT 2022
Trappc9 Deficiency Impairs the Plasticity of Stem Cells.
International journal of molecular sciences
Usman M,Li Y,Ke Y,Chhetri G,Islam MA,Wang Z,Li X
Thu Apr 28 00:00:00 EDT 2022
An oxygen-adaptive interaction between SNHG12 and occludin maintains blood-brain barrier integrity.
Cell reports
Li Y,Wei JY,Liu H,Wang KJ,Jin SN,Su ZK,Wang HJ,Shi JX,Li B,Shang DS,Fang WG,Qin XX,Zhao WD,Chen YH
Tue Apr 12 00:00:00 EDT 2022
AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.
Cancer communications (London, England)
Wei R,Zhu Y,Zhang Y,Zhao W,Yu X,Wang L,Gu C,Gu X,Yang Y
Tue Nov 01 00:00:00 EDT 2022
AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.
Cancer communications (London, England)
Wei R,Zhu Y,Zhang Y,Zhao W,Yu X,Wang L,Gu C,Gu X,Yang Y
Tue Nov 01 00:00:00 EDT 2022
AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.
Cancer communications (London, England)
Wei R,Zhu Y,Zhang Y,Zhao W,Yu X,Wang L,Gu C,Gu X,Yang Y
Tue Nov 01 00:00:00 EDT 2022
AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation.
Cancer communications (London, England)
Wei R,Zhu Y,Zhang Y,Zhao W,Yu X,Wang L,Gu C,Gu X,Yang Y
Tue Nov 01 00:00:00 EDT 2022
Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.
Nature communications
Lim RG,Al-Dalahmah O,Wu J,Gold MP,Reidling JC,Tang G,Adam M,Dansu DK,Park HJ,Casaccia P,Miramontes R,Reyes-Ortiz AM,Lau A,Hickman RA,Khan F,Paryani F,Tang A,Ofori K,Miyoshi E,Michael N,McClure N,Flowers XE,Vonsattel JP,Davidson S,Menon V,Swarup V,Fraenkel E,Goldman JE,Thompson LM
Wed Dec 21 00:00:00 EST 2022
Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages.
Cell reports
Wang Y,Wang Y,Ding L,Ren X,Wang B,Wang L,Zhao S,Yue X,Wu Z,Li C,Liang X,Ma C,Gao L
Tue Nov 29 00:00:00 EST 2022
Phosphoproteomics revealed cellular signals immediately responding to disruption of cancer amino acid homeostasis induced by inhibition of L-type amino acid transporter 1.
Cancer & metabolism
Okanishi H,Ohgaki R,Xu M,Endou H,Kanai Y
Thu Nov 10 00:00:00 EST 2022
Transformer 2 alpha homolog is a downstream gene of hypoxia-inducible factor 1 subunit alpha and is involved in the progression of pancreatic cancer.
Bioengineered
Cao W,Lei S,Zeng Z,Xiao C,Sun B,Xie P,Li Y,Luo D,Yu W
Sun May 01 00:00:00 EDT 2022
lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.
Molecular therapy : the journal of the American Society of Gene Therapy
Wang X,Zheng S,Yang F,Zhang W,Zhao D,Xue X,Lin Q,He Y,Hu G,Hu Y
Wed Mar 02 00:00:00 EST 2022
Babao Dan inhibits lymphangiogenesis of gastric cancer in vitro and in vivo via lncRNA-ANRIL/VEGF-C/VEGFR-3 signaling axis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Guan J,Guan B,Shang H,Peng J,Yang H,Lin J
Sat Oct 01 00:00:00 EDT 2022
Role of SLC39A6 in the development and progression of liver cancer.
Oncology letters
Wan Z,Wang X
Tue Mar 01 00:00:00 EST 2022
An RRx-001 Analogue With Potent Anti-NLRP3 Inflammasome Activity but Without High-Energy Nitro Functional Groups.
Frontiers in pharmacology
Lin H,Yang M,Li C,Lin B,Deng X,He H,Zhou R
Tue Mar 08 00:00:00 EST 2022
Role of BDNF/ProBDNF Imbalance in Postoperative Cognitive Dysfunction by Modulating Synaptic Plasticity in Aged Mice.
Frontiers in aging neuroscience
Xue Z,Shui M,Lin X,Sun Y,Liu J,Wei C,Wu A,Li T
Tue Apr 05 00:00:00 EDT 2022
Silent information regulator 1 ameliorates oxidative stress injury via PGC-1α/PPARγ-Nrf2 pathway after ischemic stroke in rat.
Brain research bulletin
Zhou Y,Peng L,Li Y,Zhao Y
Sat Jan 01 00:00:00 EST 2022
Trehalose improves palmitic acid-induced apoptosis of osteoblasts by regulating SIRT3-medicated autophagy via the AMPK/mTOR/ULK1 pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Cao L,Zhou S,Qiu X,Qiu S
Thu Sep 01 00:00:00 EDT 2022
Siah1 promotes the proliferation of NSCLC cells through ubiquitinating and stabilizing Notch1.
Experimental cell research
Liu Y,Li Q,Geng L,Zhou X,Zhou X,Dong Y,Zhang Y
Sat Oct 01 00:00:00 EDT 2022
Saikosaponin D Inhibited IL-1β Induced ATDC 5 Chondrocytes Apoptosis In Vitro and Delayed Articular Cartilage Degeneration in OA Model Mice In Vivo.
Frontiers in pharmacology
Wu X,Zhao K,Fang X,Lu F,Cheng P,Song X,Zhang W,Yao C,Zhu J,Chen H
Tue Apr 05 00:00:00 EDT 2022
Sleeve gastrectomy suppresses hepatic de novo cholesterogenesis and improves hepatic cholesterol accumulation in obese rats with type 2 diabetes mellitus.
Nutrition (Burbank, Los Angeles County, Calif.)
Chen F,Liu B
Tue Feb 01 00:00:00 EST 2022
Hoxa9/meis1-transgenic zebrafish develops acute myeloid leukaemia-like disease with rapid onset and high penetrance.
Open biology
Wang W,Li H,Huang M,Wang X,Li W,Qian X,Jing L
Sat Oct 01 00:00:00 EDT 2022
Cinnamic Aldehyde, the main monomer component of Cinnamon, exhibits anti-inflammatory property in OA synovial fibroblasts via TLR4/MyD88 pathway.
Journal of cellular and molecular medicine
Chen P,Zhou J,Ruan A,Zeng L,Liu J,Wang Q
Tue Feb 01 00:00:00 EST 2022
Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression.
Brain : a journal of neurology
Li S,Li J,Liu J,Wang J,Li X,Huo Y,Li Y,Liu Y,Li M,Xiao X,Luo XJ
Mon Apr 18 00:00:00 EDT 2022
CBX4-dependent regulation of HDAC3 nuclear translocation reduces Bmp2-induced osteoblastic differentiation and calcification in adamantinomatous craniopharyngioma.
Cell communication and signaling : CCS
Yan X,Kang D,Lin Y,Qi S,Jiang C
Mon Jan 03 00:00:00 EST 2022
Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation.
Pharmacological research
Li X,Zhang Y,Zhao Y,Zhou Y,Han Q,Yang Y,Zhang L,Shi L,Jin X,Zhang R,Gao H,Xue G,Li D,Zhang ZR,Lu Y,Yang B,Pan Z
Mon Aug 01 00:00:00 EDT 2022
PPARγ Alleviates Sepsis-Induced Liver Injury by Inhibiting Hepatocyte Pyroptosis via Inhibition of the ROS/TXNIP/NLRP3 Signaling Pathway.
Oxidative medicine and cellular longevity
Li Z,Liu T,Feng Y,Tong Y,Jia Y,Wang C,Cui R,Qu K,Liu C,Zhang J
Fri Mar 18 00:00:00 EDT 2022
High-throughput membrane-anchored proteome screening reveals PIEZO1 as a promising antibody-drug target for human esophageal squamous cell carcinoma.
Cancer medicine
Qin X,Ni Z,Jiang J,Liu X,Dong X,Li M,Miao K,Rao S,Zhang W,Cai K
Sat Oct 01 00:00:00 EDT 2022
FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon.
Journal of virology
Dong S,Kong N,Wang C,Li Y,Sun D,Qin W,Zhai H,Zhai X,Yang X,Ye C,Ye M,Liu C,Yu L,Zheng H,Tong W,Yu H,Zhang W,Tong G,Shan T
Wed Jul 13 00:00:00 EDT 2022
FUBP3 Degrades the Porcine Epidemic Diarrhea Virus Nucleocapsid Protein and Induces the Production of Type I Interferon.
Journal of virology
Dong S,Kong N,Wang C,Li Y,Sun D,Qin W,Zhai H,Zhai X,Yang X,Ye C,Ye M,Liu C,Yu L,Zheng H,Tong W,Yu H,Zhang W,Tong G,Shan T
Wed Jul 13 00:00:00 EDT 2022
Malic enzyme 2 maintains protein stability of mutant p53 through 2-hydroxyglutarate.
Nature metabolism
Zhao M,Yao P,Mao Y,Wu J,Wang W,Geng C,Cheng J,Du W,Jiang P
Tue Feb 01 00:00:00 EST 2022
Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.
Environmental toxicology and pharmacology
Xu Q,Zhou L,Ri H,Li X,Zhang X,Qi W,Ye L
Tue Nov 01 00:00:00 EDT 2022
CXCL12/CXCR7/β-arrestin1 biased signal promotes epithelial-to-mesenchymal transition of colorectal cancer by repressing miRNAs through YAP1 nuclear translocation.
Cell & bioscience
Si M,Song Y,Wang X,Wang D,Liu X,Qu X,Song Z,Yu X
Sun Oct 09 00:00:00 EDT 2022
EML4-ALK G1202R mutation induces EMT and confers resistance to ceritinib in NSCLC cells via activation of STAT3/Slug signaling.
Cellular signalling
Shen J,Meng Y,Wang K,Gao M,Du J,Wang J,Li Z,Zuo D,Wu Y
Fri Apr 01 00:00:00 EDT 2022
Salubrinal-mediated activation of eIF2α signaling improves oxidative stress-induced BMSCs senescence and senile osteoporosis.
Biochemical and biophysical research communications
Li L,Hu G,Xie R,Yang J,Shi X,Jia Z,Qu X,Wang M,Wu Y
Sat Jun 25 00:00:00 EDT 2022
Dan-Shen-Yin Granules Prevent Hypoxia-Induced Pulmonary Hypertension via STAT3/HIF-1α/VEGF and FAK/AKT Signaling Pathways.
Frontiers in pharmacology
Wang RR,Yuan TY,Chen D,Chen YC,Sun SC,Wang SB,Kong LL,Fang LH,Du GH
Sat Jul 16 00:00:00 EDT 2022
Spatial Training Attenuates Long-Term Alzheimer's Disease-Related Pathogenic Processes in APP/PS1 Mice.
Journal of Alzheimer's disease : JAD
Zhao Y,Bao J,Liu W,Gong X,Liang Z,Li W,Wu M,Xiao Y,Sun B,Wang X,Wang JZ,Wang J,Shu X
Thu Mar 03 00:00:00 EST 2022
Protein disulfide isomerase blocks the interaction of LC3II-PHB2 and promotes mTOR signaling to regulate autophagy and radio/chemo-sensitivity.
Cell death & disease
Wang R,Shang Y,Chen B,Xu F,Zhang J,Zhang Z,Zhao X,Wan X,Xu A,Wu L,Zhao G
Thu Oct 06 00:00:00 EDT 2022
MicroRNA-146a-5p-modified human umbilical cord mesenchymal stem cells enhance protection against diabetic nephropathy in rats through facilitating M2 macrophage polarization.
Stem cell research & therapy
Zhang Y,Le X,Zheng S,Zhang K,He J,Liu M,Tu C,Rao W,Du H,Ouyang Y,Li C,Wu D
Wed Apr 27 00:00:00 EDT 2022
Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas.
Molecular cell
Shi Z,Ge X,Li M,Yin J,Wang X,Zhang J,Chen D,Li X,Wang X,Ji J,You Y,Qian X
Thu Oct 20 00:00:00 EDT 2022
Small Extracellular Vesicles Containing miR-34c Derived from Bone Marrow Mesenchymal Stem Cells Regulates Epithelial Sodium Channel via Targeting MARCKS.
International journal of molecular sciences
Hua Y,Han A,Yu T,Hou Y,Ding Y,Nie H
Fri May 06 00:00:00 EDT 2022
Pulsed electromagnetic field alleviates synovitis and inhibits the NLRP3/Caspase-1/GSDMD signaling pathway in osteoarthritis rats.
Electromagnetic biology and medicine
Liu J,Huang X,Zhou J,Li L,Xiao H,Qu M,Sun Z
Sun Jan 02 00:00:00 EST 2022
Targeting the SREBP-1/Hsa-Mir-497/SCAP/FASN Oncometabolic Axis Inhibits the Cancer Stem-like and Chemoresistant Phenotype of Non-Small Cell Lung Carcinoma Cells.
International journal of molecular sciences
Tiong TY,Weng PW,Wang CH,Setiawan SA,Yadav VK,Pikatan NW,Fong IH,Yeh CT,Hsu CH,Kuo KT
Thu Jun 30 00:00:00 EDT 2022
Ckip-1 Mediates P. gingivalis-Suppressed Cementoblast Mineralization.
Journal of dental research
Huang X,Ma L,Wang X,Wang H,Peng Y,Gao X,Huang H,Chen Y,Zhang Y,Cao Z
Sun May 01 00:00:00 EDT 2022
Transcriptional regulator CTR9 promotes hepatocellular carcinoma progression and metastasis via increasing PEG10 transcriptional activity.
Acta pharmacologica Sinica
Zhang B,Liu ZY,Wu R,Zhang CM,Cao K,Shan WG,Liu Z,Ji M,Tian ZL,Sethi G,Shi HL,Wang RH
Mon Aug 01 00:00:00 EDT 2022
Xihuang pills induce apoptosis in hepatocellular carcinoma by suppressing phosphoinositide 3-kinase/protein kinase-B/mechanistic target of rapamycin pathway.
World journal of gastrointestinal oncology
Teng YJ,Deng Z,Ouyang ZG,Zhou Q,Mei S,Fan XX,Wu YR,Long HP,Fang LY,Yin DL,Zhang BY,Guo YM,Zhu WH,Huang Z,Zheng P,Ning DM,Tian XF
Fri Apr 15 00:00:00 EDT 2022
Thioredoxin-Interacting Protein (TXNIP) Knockdown Protects against Sepsis-Induced Brain Injury and Cognitive Decline in Mice by Suppressing Oxidative Stress and Neuroinflammation.
Oxidative medicine and cellular longevity
Zhang Y,Xing CJ,Liu X,Li YH,Jia J,Feng JG,Yang CJ,Chen Y,Zhou J
Thu May 19 00:00:00 EDT 2022
PIKE-A Modulates Mitochondrial Metabolism through Increasing SDHA Expression Mediated by STAT3/FTO Axis.
International journal of molecular sciences
Sun M,Yan Q,Qiao Y,Zhao H,Wang Y,Shan C,Zhang S
Sun Sep 25 00:00:00 EDT 2022
Viral evasion of PKR restriction by reprogramming cellular stress granules.
Proceedings of the National Academy of Sciences of the United States of America
Gao P,Liu Y,Wang H,Chai Y,Weng W,Zhang Y,Zhou L,Ge X,Guo X,Han J,Yang H
Tue Jul 19 00:00:00 EDT 2022
COOH-terminal fragment of APP interacts with p62, forms an aggregate, and induces autophagic degradation in Alzheimer's cell model.
American journal of physiology. Cell physiology
Tanaka K,Kuramoto K,Nakagawa T,Nomura Y,Ozawa K,Hosoi T
Thu Dec 01 00:00:00 EST 2022
Proteomic Mapping and Targeting of Mitotic Pericentriolar Material in Tumors Bearing Centrosome Amplification.
Cancer research
Xie B,Pu Y,Yang F,Chen W,Yue W,Ma J,Zhang N,Jiang Y,Wu J,Lin Y,Liang X,Wang C,Zou P,Li M
Mon Jul 18 00:00:00 EDT 2022
Metformin alleviates HFD-induced oxidative stress in hepatocyte via activating SIRT6/PGC-1α/ENDOG signaling.
Clinical science (London, England : 1979)
Gao S,Yang Q,Liu Z,Kong W,Chen J,Li X,Peng Y,Bao M,Bian X,Zhang Y,Jiang Q,Li Z,Zhang Y,Yan F,Ye J
Wed Nov 30 00:00:00 EST 2022
Multistage targeting and dual inhibiting strategies based on bioengineered tumor matrix microenvironment-mediated protein nanocages for enhancing cancer biotherapy.
Bioengineering & translational medicine
Hu F,Deng C,Zhou Y,Liu Y,Zhang T,Zhang P,Zhao Z,Miao H,Zheng W,Zhang W,Wang M,Ma X
Sun May 01 00:00:00 EDT 2022
Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy.
Molecular therapy. Nucleic acids
Wang Z,Chang Y,Liu Y,Liu B,Zhen J,Li X,Lin J,Yu Q,Lv Z,Wang R
Tue Jun 14 00:00:00 EDT 2022
Characterization of Mitochondrial Alterations in Aicardi-Goutières Patients Mutated in RNASEH2A and RNASEH2B Genes.
International journal of molecular sciences
Dragoni F,Garau J,Sproviero D,Orcesi S,Varesio C,De Siervi S,Gagliardi S,Cereda C,Pansarasa O
Mon Nov 21 00:00:00 EST 2022
MgIG exerts therapeutic effects on crizotinib-induced hepatotoxicity by limiting ROS-mediated autophagy and pyroptosis.
Journal of cellular and molecular medicine
Li M,Wang C,Yu Z,Lan Q,Xu S,Ye Z,Li R,Ying L,Zhang X,Zhou Z
Mon Aug 01 00:00:00 EDT 2022
Curcumin attenuates isoniazid-induced hepatotoxicity by upregulating the SIRT1/PGC-1α/NRF1 pathway.
Journal of applied toxicology : JAT
Li Y,Luo WW,Cheng X,Xiang HR,He B,Zhang QZ,Peng WX
Fri Jul 01 00:00:00 EDT 2022
Induction of endothelial barrier dysfunction by serum factors in rats subjected to traumatic brain injury and hemorrhagic shock.
Physiological reports
Ke Y,Proctor JL,Zhang C,Medina J,Miller CHT,Kim J,Grissom TE,Birukova AA,Fiskum GM,Birukov KG
Fri Jul 01 00:00:00 EDT 2022
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Cancer biology & therapy
Zhang S,Cao S,Gong M,Zhang W,Zhang W,Zhu Z,Wu S,Yue Y,Qian W,Ma Q,Wang S,Wang Z
Sat Dec 31 00:00:00 EST 2022
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Cancer biology & therapy
Zhang S,Cao S,Gong M,Zhang W,Zhang W,Zhu Z,Wu S,Yue Y,Qian W,Ma Q,Wang S,Wang Z
Sat Dec 31 00:00:00 EST 2022
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Cancer biology & therapy
Zhang S,Cao S,Gong M,Zhang W,Zhang W,Zhu Z,Wu S,Yue Y,Qian W,Ma Q,Wang S,Wang Z
Sat Dec 31 00:00:00 EST 2022
Mechanically activated ion channel Piezo1 contributes to melanoma malignant progression through AKT/mTOR signaling.
Cancer biology & therapy
Zhang S,Cao S,Gong M,Zhang W,Zhang W,Zhu Z,Wu S,Yue Y,Qian W,Ma Q,Wang S,Wang Z
Sat Dec 31 00:00:00 EST 2022
m6A modifications regulate intestinal immunity and rotavirus infection.
eLife
Wang A,Tao W,Tong J,Gao J,Wang J,Hou G,Qian C,Zhang G,Li R,Wang D,Ren X,Zhang K,Ding S,Flavell RA,Li H,Pan W,Zhu S
Mon Jan 31 00:00:00 EST 2022
Catalpol Exerts Antidepressant-Like Effects by Enhancing Anti-oxidation and Neurotrophy and Inhibiting Neuroinflammation via Activation of HO-1.
Neurochemical research
Wu X,Liu C,Wang J,Guan Y,Song L,Chen R,Gong M
Sat Oct 01 00:00:00 EDT 2022
c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia.
Apoptosis : an international journal on programmed cell death
Liu S,Qiao X,Wu S,Gai Y,Su Y,Edwards H,Wang Y,Lin H,Taub JW,Wang G,Ge Y
Thu Dec 01 00:00:00 EST 2022
Recombinant ACE2 protein protects against acute lung injury induced by SARS-CoV-2 spike RBD protein.
Critical care (London, England)
Zhang L,Zhang Y,Qin X,Jiang X,Zhang J,Mao L,Jiang Z,Jiang Y,Liu G,Qiu J,Chen C,Qiu F,Zou Z
Thu Jun 09 00:00:00 EDT 2022
Nonstructural Protein NSs Activates Inflammasome and Pyroptosis through Interaction with NLRP3 in Human Microglial Cells Infected with Severe Fever with Thrombocytopenia Syndrome Bandavirus.
Journal of virology
Gao C,Yu Y,Wen C,Li Z,Ding H,Qi X,Cardona CJ,Xing Z
Wed Jul 13 00:00:00 EDT 2022
Nonstructural Protein NSs Activates Inflammasome and Pyroptosis through Interaction with NLRP3 in Human Microglial Cells Infected with Severe Fever with Thrombocytopenia Syndrome Bandavirus.
Journal of virology
Gao C,Yu Y,Wen C,Li Z,Ding H,Qi X,Cardona CJ,Xing Z
Wed Jul 13 00:00:00 EDT 2022
Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer.
Cell death & disease
Tang X,Liang Y,Sun G,He Q,Hou Z,Jiang X,Gao P,Qu H
Tue Oct 04 00:00:00 EDT 2022
C. elegans monitor energy status via the AMPK pathway to trigger innate immune responses against bacterial pathogens.
Communications biology
Ju S,Chen H,Wang S,Lin J,Ma Y,Aroian RV,Peng D,Sun M
Thu Jun 30 00:00:00 EDT 2022
Molecular mechanism of the TGF‑β/Smad7 signaling pathway in ulcerative colitis.
Molecular medicine reports
Bai B,Li H,Han L,Mei Y,Hu C,Mei Q,Xu J,Liu X
Fri Apr 01 00:00:00 EDT 2022
Therapeutic strategies targeting uPAR potentiate anti-PD-1 efficacy in diffuse-type gastric cancer.
Science advances
Qin L,Wang L,Zhang J,Zhou H,Yang Z,Wang Y,Cai W,Wen F,Jiang X,Zhang T,Ye H,Long B,Qin J,Shi W,Guan X,Yu Z,Yang J,Wang Q,Jiao Z
Fri May 27 00:00:00 EDT 2022
CCT4 knockdown enhances the sensitivity of cisplatin by inhibiting glycolysis in human esophageal squamous cell carcinomas.
Molecular carcinogenesis
Fang J,Ma Y,Li Y,Li J,Zhang X,Han X,Ma S,Guan F
Tue Nov 01 00:00:00 EDT 2022
Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19.
Cell biology and toxicology
Xie C,Zhu J,Huang C,Yang X,Wang X,Meng Y,Geng S,Wu J,Shen H,Hu Z,Meng Z,Li X,Zhong C
Fri Apr 01 00:00:00 EDT 2022
A dual crosslinked hydrogel-mediated integrated peptides and BMSC therapy for myocardial regeneration.
Journal of controlled release : official journal of the Controlled Release Society
Zheng Z,Guo Z,Zhong F,Wang B,Liu L,Ma W,Yu CY,Wei H
Fri Jul 01 00:00:00 EDT 2022
Macrophage-targeted delivery of siRNA to silence Mecp2 gene expression attenuates pulmonary fibrosis.
Bioengineering & translational medicine
Mou Y,Wu GR,Wang Q,Pan T,Zhang L,Xu Y,Xiong W,Zhou Q,Wang Y
Sun May 01 00:00:00 EDT 2022
Bacillus subtilis WB800N alleviates diabetic wounds in mice by regulating gut microbiota homeostasis and TLR2.
Journal of applied microbiology
Mi J,Xie C,Zeng L,Zhu Z,Chen N,He Q,Xu X,Xie H,Zhou J,Li L,Liao J
Mon Aug 01 00:00:00 EDT 2022
Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.
Pharmaceuticals (Basel, Switzerland)
Liu T,Gao H,Zhang Y,Wang S,Lu M,Dai X,Liu Y,Shi H,Xu T,Yin J,Gao S,Wang L,Zhang D
Mon Nov 21 00:00:00 EST 2022
Inflammatory-Dependent Bidirectional Effect of Bile Acids on NLRP3 Inflammasome and Its Role in Ameliorating CPT-11-Induced Colitis.
Frontiers in pharmacology
Liao C,Wang D,Qin S,Zhang Y,Chen J,Xu R,Xu F,Zhang P
Sat Jul 16 00:00:00 EDT 2022
TGR5 Agonist INT-777 Alleviates Inflammatory Neurodegeneration in Parkinson's Disease Mouse Model by Modulating Mitochondrial Dynamics in Microglia.
Neuroscience
Huang R,Gao Y,Chen J,Duan Q,He P,Zhang J,Huang H,Zhang Q,Ma G,Zhang Y,Nie K,Wang L
Tue May 10 00:00:00 EDT 2022
AMG487 inhibits PRRSV replication and ameliorates lung injury in pig lung xenografts by down-regulating the expression of ANXA2.
Antiviral research
Liu J,Yao L,Huang S,Wang B,Li L,Li L,Gu W,Xiao S,Liu G
Wed Jun 01 00:00:00 EDT 2022
Umbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling pathway.
Molecular biology reports
Wang Y,Liu J,Yu B,Jin Y,Li J,Ma X,Yu J,Niu J,Liang X
Mon Aug 01 00:00:00 EDT 2022
Interleukin 7 inhibit autophagy via P53 regulated AMPK/mTOR signaling pathway in non-small cell lung cancer.
Scientific reports
Zhu Y,Jiang X,Ding Z,Ming J
Fri Jul 01 00:00:00 EDT 2022
Amentoflavone attenuates Listeria monocytogenes pathogenicity through an LLO-dependent mechanism.
British journal of pharmacology
Tingting W,Tianqi F,Xinyu W,Can Z,Xue S,Xuming D,Jianfeng W
Fri Jul 01 00:00:00 EDT 2022
PDGF-D-PDGFRβ signaling enhances IL-15-mediated human natural killer cell survival.
Proceedings of the National Academy of Sciences of the United States of America
Ma S,Tang T,Wu X,Mansour AG,Lu T,Zhang J,Wang LS,Caligiuri MA,Yu J
Tue Jan 18 00:00:00 EST 2022
Discovery of 3,4-Dihydrobenzo[f][1,4]oxazepin-5(2H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects.
Journal of medicinal chemistry
Li Y,Zhang L,Yang R,Qiao Z,Wu M,Huang C,Tian C,Luo X,Yang W,Zhang Y,Li L,Yang S
Thu Feb 10 00:00:00 EST 2022
DNA methylation of miR-138 regulates cell proliferation and EMT in cervical cancer by targeting EZH2.
BMC cancer
Chen R,Gan Q,Zhao S,Zhang D,Wang S,Yao L,Yuan M,Cheng J
Tue May 03 00:00:00 EDT 2022
Ultrasound-based radiomics for the evaluation of fetal rat lung maturity: A noninvasive assessment method (Ultrasound-based radiomics in fetal rat lung).
Prenatal diagnosis
Du Y,Jiao J,Cao A,Ji C,Li M,Ji C,Wu Y,Guo Y,Wang Y,Zhou J,Ren Y
Sat Oct 01 00:00:00 EDT 2022
LncRNA ANRIL mediates endothelial dysfunction through BDNF downregulation in chronic kidney disease.
Cell death & disease
Su H,Liu B,Chen H,Zhang T,Huang T,Liu Y,Wang C,Ma Q,Wang Q,Lv Z,Wang R
Fri Jul 29 00:00:00 EDT 2022
Tuftelin 1 Facilitates Hepatocellular Carcinoma Progression through Regulation of Lipogenesis and Focal Adhesion Maturation.
Journal of immunology research
Zhu L,Zhou KX,Ma MZ,Yao LL,Zhang YL,Li H,Du C,Yang XM
Fri Jul 01 00:00:00 EDT 2022
Proteomic analysis reveals that Xbp1s promotes hypoxic pulmonary hypertension through the p-JNK MAPK pathway.
Journal of cellular physiology
Jiang H,Niu Y,He Y,Li X,Xu Y,Liu X
Tue Mar 01 00:00:00 EST 2022
Rosmarinic Acid Decreases the Malignancy of Pancreatic Cancer Through Inhibiting Gli1 Signaling.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhou X,Wang W,Li Z,Chen L,Wen C,Ruan Q,Xu Z,Liu R,Xu J,Bai Y,Deng J
Sat Jan 01 00:00:00 EST 2022
LncGSAR Controls Ovarian Granulosa Cell Steroidogenesis via Sponging MiR-125b to Activate SCAP/SREBP Pathway.
International journal of molecular sciences
Wang Y,Guo Y,Duan C,Li J,Ji S,Yan H,Liu Y,Zhang Y
Wed Oct 12 00:00:00 EDT 2022
Total extract of Abelmoschus manihot L. alleviates uric acid-induced renal tubular epithelial injury via inhibition of caspase-8/caspase-3/NLRP3/GSDME signaling.
Frontiers in pharmacology
Ding Z,Zhao J,Wang X,Li W,Chen C,Yong C,Zhu Y,Tian F,Liu L,Yu M,Zhou E,Gu L,Yao C,Gao K
Wed Sep 07 00:00:00 EDT 2022
miR-328-5p Induces Human Intervertebral Disc Degeneration by Targeting WWP2.
Oxidative medicine and cellular longevity
Yan J,Wu LG,Zhang M,Fang T,Pan W,Zhao JL,Zhou Q
Tue Oct 11 00:00:00 EDT 2022
Epoxymicheliolide prevents dextran sulfate sodium-induced colitis in mice by inhibiting TAK1-NF-κB pathway and activating Keap1-NRF2 signaling in macrophages.
International immunopharmacology
He J,Liu L,Liu X,Chen H,Liu K,Huang N,Wang Y
Thu Dec 01 00:00:00 EST 2022
Nr2f2 Overexpression Aggravates Ferroptosis and Mitochondrial Dysfunction by Regulating the PGC-1α Signaling in Diabetes-Induced Heart Failure Mice.
Mediators of inflammation
Miao W,Chen M,Chen M,Cui C,Zhu Y,Luo X,Wu B
Mon Sep 12 00:00:00 EDT 2022
Transcriptomic Analysis of Dysregulated Genes of the nDNA-mtDNA Axis in a Mouse Model of Dilated Cardiomyopathy.
Frontiers in genetics
Ziemann M,Wu W,Deng XL,Du XJ
Sat Jul 16 00:00:00 EDT 2022
Hyaluronic acids mediate the infiltration, migration, and M2 polarization of macrophages: evaluating metabolic molecular phenotypes in gliomas.
Molecular oncology
Zhang H,Zhang N,Dai Z,Wang Z,Zhang X,Liang X,Zhang L,Feng S,Wu W,Ye W,Zhang J,Luo P,Liu Z,Cheng Q,Liu Z
Thu Dec 01 00:00:00 EST 2022
Effect of Ultraviolet B Irradiation on Melanin Content Accompanied by the Activation of p62/GATA4-Mediated Premature Senescence in HaCaT Cells.
Dose-response : a publication of International Hormesis Society
Yan J,Ma LP,Liu F,Sun B,Tian M,Lu X,Liu HX,Gao L,Liu QJ
Sun May 01 00:00:00 EDT 2022
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection.
Molecular brain
Xu B,Yang R,Yang B,Li L,Chen J,Fu J,Qu X,Huo D,Tan C,Chen H,Peng Z,Wang X
Mon Jan 03 00:00:00 EST 2022
BPIFA2 as a Novel Early Biomarker to Identify Fatal Radiation Injury After Radiation Exposure.
Dose-response : a publication of International Hormesis Society
He L,Zhou S,Li W,Wang Q,Qi Z,Zhou P,Wang Z,Chen J,Li Y,Lin Z
Fri May 06 00:00:00 EDT 2022
LncRNA LINC01857 reduces metastasis and angiogenesis in breast cancer cells via regulating miR-2052/CENPQ axis.
Open medicine (Warsaw, Poland)
Qian W,Yang L,Ni Y,Yin F,Qin L,Yang Y
Wed Sep 07 00:00:00 EDT 2022
Alternative splicing of the human rhomboid family-1 gene RHBDF1 inhibits epidermal growth factor receptor activation.
The Journal of biological chemistry
Ji R,Shi Q,Cao Y,Zhang J,Zhao C,Zhao H,Sayyed Y,Fu L,Li LY
Wed Jun 01 00:00:00 EDT 2022
Exploitation of tumor antigens and construction of immune subtype classifier for mRNA vaccine development in bladder cancer.
Frontiers in immunology
Zhang X,Zhang Y,Zhao L,Wang J,Li J,Wang X,Zhang M,Hu X
Tue Dec 27 00:00:00 EST 2022
The Gut Microbiota Dysbiosis in Preeclampsia Contributed to Trophoblast Cell Proliferation, Invasion, and Migration via lncRNA BC030099/NF-κB Pathway.
Mediators of inflammation
Tang R,Xiao G,Jian Y,Yuan Q,Jiang C,Wang W
Wed Jul 06 00:00:00 EDT 2022
Identification of amino acid residues in the MT-loop of MT1-MMP critical for its ability to cleave low-density lipoprotein receptor.
Frontiers in cardiovascular medicine
Wang M,Alabi A,Gu HM,Gill G,Zhang Z,Jarad S,Xia XD,Shen Y,Wang GQ,Zhang DW
Tue Sep 13 00:00:00 EDT 2022
miR-138-5p Inhibits the Growth and Invasion of Glioma Cells by Regulating WEE1.
Analytical cellular pathology (Amsterdam)
Gong J,Tang Z,Yu Z,Deng Z,Liu Y,Ren N,Wang L,He Z
Mon Apr 04 00:00:00 EDT 2022
Modification of taxifolin particles with an enteric coating material promotes repair of acute liver injury in mice through modulation of inflammation and autophagy signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ding Q,Chen K,Liu X,Ding C,Zhao Y,Sun S,Zhang Y,Zhang J,Liu S,Liu W
Mon Aug 01 00:00:00 EDT 2022
Berberine Ameliorates Inflammation in Acute Lung Injury via NF-κB/Nlrp3 Signaling Pathway.
Frontiers in nutrition
Chen J,Huang Y,Bian X,He Y
Tue Mar 15 00:00:00 EDT 2022
Bcl-2 hijacks the arsenic trioxide resistance in SH-SY5Y cells.
Journal of cellular and molecular medicine
Wang J,Peng X,Yang D,Guo M,Xu X,Yin F,Wang Y,Huang J,Zhan L,Qi Z
Sat Jan 01 00:00:00 EST 2022
Differential Expression of CB1 Cannabinoid Receptor and Cannabinoid Receptor Interacting Protein 1a in Labor.
Cannabis and cannabinoid research
Kozakiewicz ML,Zhang J,Leone-Kabler S,Yamaleyeva LM,McDonald AG,Brost BC,Howlett AC
Wed Jun 01 00:00:00 EDT 2022
Pseudogene CSPG4P12 affects the biological behavior of non‑small cell lung cancer by Bcl‑2/Bax mitochondrial apoptosis pathway.
Experimental and therapeutic medicine
Hu W,Wu H,Li A,Zheng X,Zhang W,Tian Q,Zhang X
Thu Dec 01 00:00:00 EST 2022
Salubrinal protects against inflammatory response in macrophage and attenuates psoriasiform skin inflammation by antagonizing NF-κB signaling pathway.
Biochemical and biophysical research communications
Shangguan Y,Chen Y,Ma Y,Zhao Y,He Y,Li W
Sat Jan 22 00:00:00 EST 2022
Targeted lipidomics analysis of lysine 179 acetylation of ACSF2 in rat hepatic stellate cells.
Prostaglandins & other lipid mediators
Wang M,Su Y,Hou C,Ren K,Liu X,Zhao S,Wang Y,Liu X
Thu Dec 01 00:00:00 EST 2022
Resident intruder paradigm-induced PMDD rat model of premenstrual irritability: behavioral phenotypes, drug intervention, and biomarkers.
Aging
Gao M,Zhang H,Gao Z,Sun Y,Xu G,Wei F,Wang J,Gao D
Sun Nov 27 00:00:00 EST 2022
Controlled Hemorrhage Sensitizes Angiotensin II-Elicited Hypertension through Activation of the Brain Renin-Angiotensin System Independently of Endoplasmic Reticulum Stress.
Oxidative medicine and cellular longevity
Wu GB,Du HB,Zhai JY,Sun S,Cui JL,Zhang Y,Zhao ZA,Wu JL,Johnson AK,Xue B,Zhao ZG,Zhang GS
Tue Mar 08 00:00:00 EST 2022
Inert Pepper aptamer-mediated endogenous mRNA recognition and imaging in living cells.
Nucleic acids research
Wang Q,Xiao F,Su H,Liu H,Xu J,Tang H,Qin S,Fang Z,Lu Z,Wu J,Weng X,Zhou X
Fri Aug 12 00:00:00 EDT 2022
G protein-coupled receptor 17 restricts rabies virus replication via BAK-mediated apoptosis.
Veterinary microbiology
Liu W,Yang Y,Zeng Z,Tian Y,Wu Q,Zhou M,Fu ZF,Zhao L
Tue Feb 01 00:00:00 EST 2022
Premature translation termination mediated non-ER stress induced ATF6 activation by a ligand-dependent ribosomal frameshifting circuit.
Nucleic acids research
Hsu HT,Murata A,Dohno C,Nakatani K,Chang K
Fri May 20 00:00:00 EDT 2022
Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway.
Brain and behavior
Liu H,He S,Li C,Wang J,Zou Q,Liao Y,Chen R
Thu Dec 01 00:00:00 EST 2022
miR-127-5p Targets JAM3 to Regulate Ferroptosis, Proliferation, and Metastasis in Malignant Meningioma Cells.
Disease markers
Zhang J,Liu Z,Dong Y
Wed Jul 13 00:00:00 EDT 2022
Mechanosensitive Piezo1 channels mediate renal fibrosis.
JCI insight
Zhao X,Kong Y,Liang B,Xu J,Lin Y,Zhou N,Li J,Jiang B,Cheng J,Li C,Wang W
Fri Apr 08 00:00:00 EDT 2022
Integrated bioinformatics analysis and screening of hub genes in polycystic ovary syndrome.
Endocrine
Qiao G,Xing J,Luo X,Zhang C,Yi J
Thu Dec 01 00:00:00 EST 2022
Structure-based discovery of Licoflavone B and Ginkgetin targeting c-Myc G-quadruplex to suppress c-Myc transcription and myeloma growth.
Chemical biology & drug design
Liu L,Geng X,Zhang J,Li S,Gao J
Sat Oct 01 00:00:00 EDT 2022
Inhibition of LSD1 with Bomedemstat Sensitizes Small Cell Lung Cancer to Immune Checkpoint Blockade and T-Cell Killing.
Clinical cancer research : an official journal of the American Association for Cancer Research
Hiatt JB,Sandborg H,Garrison SM,Arnold HU,Liao SY,Norton JP,Friesen TJ,Wu F,Sutherland KD,Rienhoff HY,Martins R,Houghton AM,Srivastava S,MacPherson D
Fri Oct 14 00:00:00 EDT 2022
Up-Regulation of TRIM32 Associated With the Poor Prognosis of Acute Myeloid Leukemia by Integrated Bioinformatics Analysis With External Validation.
Frontiers in oncology
Xu X,Qi J,Yang J,Pan T,Han H,Yang M,Han Y
Sat Jul 16 00:00:00 EDT 2022
Themis is indispensable for IL-2 and IL-15 signaling in T cells.
Science signaling
Liu Y,Cong Y,Niu Y,Yuan Y,Tan F,Lai Q,Hu Y,Hou B,Li J,Lin C,Zheng H,Dong J,Tang J,Chen Q,Brzostek J,Zhang X,Chen XL,Wang HR,Gascoigne NRJ,Xu B,Lin SH,Fu G
Tue Feb 15 00:00:00 EST 2022
Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice.
Nature communications
Wang X,Li Y,Qiang G,Wang K,Dai J,McCann M,Munoz MD,Gil V,Yu Y,Li S,Yang Z,Xu S,Cordoba-Chacon J,De Jesus DF,Sun B,Chen K,Wang Y,Liu X,Miao Q,Zhou L,Hu R,Ding Q,Kulkarni RN,Gao D,Blüher M,Liew CW
Mon Nov 28 00:00:00 EST 2022
AZD5153, a Bivalent BRD4 Inhibitor, Suppresses Hepatocarcinogenesis by Altering BRD4 Chromosomal Landscape and Modulating the Transcriptome of HCC Cells.
Frontiers in cell and developmental biology
Lin CH,Kuo JC,Li D,Koenig AB,Pan A,Yan P,Bai XF,Lee RJ,Ghoshal K
Tue Jul 26 00:00:00 EDT 2022
Cryptotanshinone attenuates LPS-induced acute lung injury by regulating metabolic reprogramming of macrophage.
Frontiers in medicine
Ye Z,Wang P,Feng G,Wang Q,Liu C,Lu J,Chen J,Liu P
Thu Feb 02 00:00:00 EST 2023
FUS Mutation Causes Disordered Lipid Metabolism in Skeletal Muscle Associated with ALS.
Molecular neurobiology
Zhou B,Zheng Y,Li X,Dong H,Yu J,Zou Y,Zhu M,Yu Y,Fang X,Zhou M,Zhang W,Yuan Y,Wang Z,Deng J,Hong D
Thu Dec 01 00:00:00 EST 2022
Palbociclib regulates intracellular lipids in mammary tumor cells by secreting lipoprotein lipase.
Pharmacological reports : PR
Fujii T,Kamishikiryo J,Morita T
Wed Jun 01 00:00:00 EDT 2022
Moringa oleifera Lam. seed extract protects kidney function in rats with diabetic nephropathy by increasing GSK-3β activity and activating the Nrf2/HO-1 pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wen Y,Liu Y,Huang Q,Liu R,Liu J,Zhang F,Liu S,Jiang Y
Sat Jan 01 00:00:00 EST 2022
Neuropeptide Y promotes hepatic apolipoprotein A1 synthesis and secretion through neuropeptide Y Y5 receptor.
Peptides
Liu B,Chen F
Mon Aug 01 00:00:00 EDT 2022
Induction of estrogen receptor β-mediated autophagy sensitizes breast cancer cells to TAD1822-7, a novel biphenyl urea taspine derivative.
Molecular biology reports
Su Q,Wu Q,Chen K,Wang J,Sarwar A,Zhang Y
Tue Feb 01 00:00:00 EST 2022
Knockdown of GBP1 inhibits BCG-induced apoptosis in macrophage RAW 264.7 cells via p38/JNK pathway.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Wang J,Liu Z,Li W,Yu J,Zhang D
Sat Jan 01 00:00:00 EST 2022
TPN171H alleviates pulmonary hypertension via inhibiting inflammation in hypoxia and monocrotaline-induced rats.
Vascular pharmacology
Zhao C,Hu L,He X,Li L,Yin M,Tettey AT,Wang Y,Shen J,Tang S,Wu C,Li Q,Wang Z,Li X
Mon Aug 01 00:00:00 EDT 2022
A Novel Pectin-Like Glycopeptide Isolated from the Fruit of Fructus Mori Impedes Aggregation and Production of Aβ42.
Journal of agricultural and food chemistry
Li S,Jin C,Gao P,Zhou W,Xiao R,Zhang Z,Liao W,Ding K
Wed Aug 17 00:00:00 EDT 2022
Wogonoside attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis through SOCS1/P53/SLC7A11 pathway.
Phytotherapy research : PTR
Liu G,Wei C,Yuan S,Zhang Z,Li J,Zhang L,Wang G,Fang L
Tue Nov 01 00:00:00 EDT 2022
Ornithine decarboxylase of the fungal pathogen Colletotrichum higginsianum plays an important role in regulating global metabolic pathways and virulence.
Environmental microbiology
Yan Y,Tang J,Yuan Q,Liu H,Huang J,Hsiang T,Bao C,Zheng L
Tue Mar 01 00:00:00 EST 2022
Probiotic Bifidobacterium breve Prevents Memory Impairment Through the Reduction of Both Amyloid-β Production and Microglia Activation in APP Knock-In Mouse.
Journal of Alzheimer's disease : JAD
Abdelhamid M,Zhou C,Ohno K,Kuhara T,Taslima F,Abdullah M,Jung CG,Michikawa M
Thu Mar 03 00:00:00 EST 2022
Overexpression of DOCK6 in oral squamous cell cancer promotes cellular migration and invasion and is associated with poor prognosis.
Archives of oral biology
Zhang ZY,Sun YY,Wang HC,Fu WN,Sun CF
Sat Jan 01 00:00:00 EST 2022
Novel Thermosensitive Hydrogel Promotes Spinal Cord Repair by Regulating Mitochondrial Function.
ACS applied materials & interfaces
Li Y,Yang L,Hu F,Xu J,Ye J,Liu S,Wang L,Zhuo M,Ran B,Zhang H,Ye J,Xiao J
Wed Jun 08 00:00:00 EDT 2022
JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage.
Ecotoxicology and environmental safety
Liu C,Wu M,Qu J,Huang X,Zeng Q,Ha M
Wed Jun 15 00:00:00 EDT 2022
Single Cell Dissection of Epithelial-Immune Cellular Interplay in Acute Kidney Injury Microenvironment.
Frontiers in immunology
Zhang M,Wu L,Deng Y,Peng F,Wang T,Zhao Y,Chen P,Liu J,Cai G,Wang L,Wu J,Chen X
Tue May 24 00:00:00 EDT 2022
Differential Expression Profile of microRNAs and Tight Junction in the Lung Tissues of Rat With Mitomycin-C-Induced Pulmonary Veno-Occlusive Disease.
Frontiers in cardiovascular medicine
Song Q,Chen P,Wu SJ,Chen Y,Zhang Y
Mon May 02 00:00:00 EDT 2022
Growth advantage of corrected hepatocytes in a juvenile model of methylmalonic acidemia following liver directed adeno-associated viral mediated nuclease-free genome editing.
Molecular genetics and metabolism
Venturoni LE,Chandler RJ,Liao J,Hoffmann V,Ramesh N,Gordo S,Chau N,Venditti CP
Wed Oct 26 00:00:00 EDT 2022
Quercetin in Tonglong Qibi decoction ameliorates testosterone-induced benign prostatic hyperplasia in rats by regulating Nrf2 signalling pathways and oxidative stress.
Andrologia
Fu W,Chen S,Zhang Z,Chen Y,You X,Li Q
Sat Oct 01 00:00:00 EDT 2022
The Pretreatment of Xiaoqinglong Decoction Alleviates Inflammation and Oxidative Damage and Up-Regulates Angiotensin-Converting Enzyme 2 in Lipopolysaccharide-Induced Septic Acute Lung Injury Rats.
Evidence-based complementary and alternative medicine : eCAM
Su JC,Cheng C,Wang CY,Zhang Y,He YT,Guo ZW,Liu XY,Liu WM,Zhang YJ,Xu SW,Zhang XY,Liu ZB,Zhang XF
Thu Oct 06 00:00:00 EDT 2022
Inhibition of TIGAR Increases Exogenous p53 and Cisplatin Combination Sensitivity in Lung Cancer Cells by Regulating Glycolytic Flux.
International journal of molecular sciences
Fu J,Yu S,Zhao X,Zhang C,Shen L,Liu Y,Yu H
Fri Dec 16 00:00:00 EST 2022
Presenilin Deficiency Increases Susceptibility to Oxidative Damage in Fibroblasts.
Frontiers in aging neuroscience
Zou K,Islam S,Sun Y,Gao Y,Nakamura T,Komano H,Tomita T,Michikawa M
Sat Jul 16 00:00:00 EDT 2022
Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance.
EMBO reports
Chen Y,Wu X,Zhang J,Pan G,Wang X,Guo X,Wang J,Cui X,Gao H,Cheng M,Yang J,Zhang C,Jiang F
Thu Feb 03 00:00:00 EST 2022
Inhibition of the NLRP3 Inflammasome Activation by Manoalide Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis.
Frontiers in cell and developmental biology
Li C,Lin H,He H,Ma M,Jiang W,Zhou R
Tue Mar 08 00:00:00 EST 2022
Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice.
Neural regeneration research
Deng LD,Qi L,Suo Q,Wu SJ,Mamtilahun M,Shi RB,Liu Z,Sun JF,Tang YH,Zhang ZJ,Yang GY,Wang JX
Thu Sep 01 00:00:00 EDT 2022
Hexokinase 2-mediated glycolysis promotes receptor activator of NF-κB ligand expression in Porphyromonas gingivalis lipopolysaccharide-treated osteoblasts.
Journal of periodontology
Yu Y,Jiang L,Li J,Lei L,Li H
Fri Jul 01 00:00:00 EDT 2022
Persistent high glucose induced EPB41L4A-AS1 inhibits glucose uptake via GCN5 mediating crotonylation and acetylation of histones and non-histones.
Clinical and translational medicine
Liao W,Xu N,Zhang H,Liao W,Wang Y,Wang S,Zhang S,Jiang Y,Xie W,Zhang Y
Tue Feb 01 00:00:00 EST 2022
Morphological changes of macrophages and their potential contribution to tendon healing.
Colloids and surfaces. B, Biointerfaces
Yang QQ,Zhang L,Zhou YL,Tang JB
Sat Jan 01 00:00:00 EST 2022
Exosome-transmitted S100A4 induces immunosuppression and non-small cell lung cancer development by activating STAT3.
Clinical and experimental immunology
Wu X,Zhang H,Jiang G,Peng M,Li C,Lu J,Jiang S,Yang X,Jiang Y
Sat Dec 31 00:00:00 EST 2022
Baicalin alleviates endometrial inflammatory injury through regulation of tight junction proteins.
Food & function
Yang D,Yin R,Lei Q,Zhu J,Nan S,Ma N,Zhu H,Chen J,Han L,Ding M,Ding Y
Mon Jun 20 00:00:00 EDT 2022
Myricetin exerts its antiviral activity against infectious bronchitis virus by inhibiting the deubiquitinating activity of papain-like protease.
Poultry science
Peng S,Fang C,He H,Song X,Zhao X,Zou Y,Li L,Jia R,Yin Z
Tue Mar 01 00:00:00 EST 2022
VAMP4 regulates insulin levels by targeting secretory granules to lysosomes.
The Journal of cell biology
Li M,Feng F,Feng H,Hu P,Xue Y,Xu T,Song E
Mon Oct 03 00:00:00 EDT 2022
Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor.
EBioMedicine
Zhang T,Guo Z,Huo X,Gong Y,Li C,Huang J,Wang Y,Feng H,Ma X,Jiang C,Yin Q,Xue L
Tue Mar 01 00:00:00 EST 2022
Administration of miR-195 Inhibitor Enhances Memory Function Through Improving Synaptic Degradation and Mitochondrial Dysfunction of the Hippocampal Neurons in SAMP8 Mice.
Journal of Alzheimer's disease : JAD
Gao Z,Zhang R,Jiang L,Zhou H,Wang Q,Ma Y,Zhang D,Qin Y,Tian P,Zhang N,Shi Z,Xu S
Thu Mar 03 00:00:00 EST 2022
Acidic Tumor Microenvironment Promotes Pancreatic Cancer through miR-451a/MEF2D Axis.
Journal of oncology
Xu J,Li Y,Li Z,Shao W,Song J,Wei J
Tue Jan 25 00:00:00 EST 2022
Overexpressed mitogen-and stress-activated protein kinase 1 promotes the resistance of cytarabine in acute myeloid leukemia through brahma related gene 1-mediated upregulation of heme oxygenase-1.
European journal of pharmacology
Zhang S,Pan C,Shang Q,Wang W,Hu T,Liu P,Chen S,Wang J,Fang Q
Tue Feb 15 00:00:00 EST 2022
Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy.
Acta pharmacologica Sinica
Yang WX,Liu Y,Zhang SM,Wang HF,Liu YF,Liu JL,Li XH,Zeng MR,Han YZ,Liu FY,Sun L,Xiao L
Tue Mar 01 00:00:00 EST 2022
Meningitic Escherichia coli-Induced Interleukin-17A Facilitates Blood-Brain Barrier Disruption via Inhibiting Proteinase 3/Protease-Activated Receptor 2 Axis.
Frontiers in cellular neuroscience
Xu B,Chen J,Fu J,Yang R,Yang B,Huo D,Tan C,Chen H,Wang X
Tue Mar 01 00:00:00 EST 2022
Urolithin A protects dopaminergic neurons in experimental models of Parkinson's disease by promoting mitochondrial biogenesis through the SIRT1/PGC-1α signaling pathway.
Food & function
Liu J,Jiang J,Qiu J,Wang L,Zhuo J,Wang B,Sun D,Yu S,Lou H
Tue Jan 04 00:00:00 EST 2022
NSUN5 promotes progression and predicts poor prognosis in hepatocellular carcinoma.
Oncology letters
Zhang XW,Wu LY,Liu HR,Huang Y,Qi Q,Zhong R,Zhu L,Gao CF,Zhou L,Yu J,Wu HG
Thu Dec 01 00:00:00 EST 2022
Recovery Infectious Enterovirus 71 by Bac-to-Bac Expression System in vitro and in vivo.
Frontiers in microbiology
Lu B,Tang Q,Wang Q,Liu X,Peng H,Zhu B,Xie L,Li Z,Wang H,Zheng Z,Wang L,Li B
Fri Apr 01 00:00:00 EDT 2022
UHRF1 shapes both the trophoblast invasion and decidual macrophage differentiation in early pregnancy.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Liu H,Wang LL,Xu QH,Wang J,Zhang YJ,Luo J,Liao AH
Fri Apr 01 00:00:00 EDT 2022
Antioxidant Activity of Acanthopanax senticosus Flavonoids in H2O2-Induced RAW 264.7 Cells and DSS-Induced Colitis in Mice.
Molecules (Basel, Switzerland)
Su J,Zhang X,Kan Q,Chu X
Sat Apr 30 00:00:00 EDT 2022
Identification of oleoylethanolamide as an endogenous ligand for HIF-3α.
Nature communications
Diao X,Ye F,Zhang M,Ren X,Tian X,Lu J,Sun X,Hou Z,Chen X,Li F,Zhuang J,Ding H,Peng C,Rastinejad F,Luo C,Wu D
Mon May 09 00:00:00 EDT 2022
Clitoria ternatea blue petal extract protects against obesity, oxidative stress, and inflammation induced by a high-fat, high-fructose diet in C57BL/6 mice.
Food research international (Ottawa, Ont.)
Wang Y,Liu T,Xie Y,Li N,Liu Y,Wen J,Zhang M,Feng W,Huang J,Guo Y,Kabbas Junior T,Wang D,Granato D
Thu Dec 01 00:00:00 EST 2022
A novel role of TCAIM: suppressing renal carcinoma growth and enhancing its sensitivity to sunitinib.
The FEBS journal
Ye Z,Ren C,Wang Q,Wang Y
Thu Sep 01 00:00:00 EDT 2022
Exosomal miR-22-3p from Mesenchymal Stem Cells Inhibits the Epithelial-Mesenchymal Transition (EMT) of Melanoma Cells by Regulating LGALS1.
Frontiers in bioscience (Landmark edition)
Chen Y,Fang Y,Li L,Luo H,Cao T,Tu B
Thu Sep 29 00:00:00 EDT 2022
SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.
Journal of medical virology
Han L,Zheng Y,Deng J,Nan ML,Xiao Y,Zhuang MW,Zhang J,Wang W,Gao C,Wang PH
Tue Nov 01 00:00:00 EDT 2022
Auxin and abscisic acid antagonistically regulate ascorbic acid production via the SlMAPK8-SlARF4-SlMYB11 module in tomato.
The Plant cell
Xu X,Zhang Q,Gao X,Wu G,Wu M,Yuan Y,Zheng X,Gong Z,Hu X,Gong M,Qi T,Li H,Luo Z,Li Z,Deng W
Thu Oct 27 00:00:00 EDT 2022
The m6A RNA Modification Quantity and the Prognostic Effect of Reader YTHDC2 in Colorectal Cancer.
Clinical Medicine Insights. Oncology
Liu T,Tang W,Chen Y,Liu Y,Xu D,Jiang Y,Zhou S,Qin X,Ren L,Chang W,Xu J
Fri Jul 29 00:00:00 EDT 2022
Chrysophanol-8-O-glucoside protects mice against acute liver injury by inhibiting autophagy in hepatic stellate cells and inflammatory response in liver-resident macrophages.
Frontiers in pharmacology
Wang T,Lu Z,Qu XH,Xiong ZY,Wu YT,Luo Y,Zhang ZY,Han XJ,Xie CF
Sat Sep 24 00:00:00 EDT 2022
Akkermansia muciniphila Colonization Alleviating High Fructose and Restraint Stress-Induced Jejunal Mucosal Barrier Disruption.
Nutrients
Yu J,Liu T,Gao Z,Liu R,Wang Z,Chen Y,Cao J,Dong Y
Sat Jul 30 00:00:00 EDT 2022
Golgi Phosphoprotein 3 Confers Radioresistance via Stabilizing EGFR in Lung Adenocarcinoma.
International journal of radiation oncology, biology, physics
Chen G,Kong P,Yang M,Hu W,Prise KM,Yu KN,Cui S,Qin F,Meng G,Almahi WA,Nie L,Han W
Fri Apr 01 00:00:00 EDT 2022
Fluid shear stress-induced down-regulation of miR-146a-5p inhibits osteoblast apoptosis via targeting SMAD4.
Physiological research
Liu X,Zhang K,Wang L,Geng B,Liu Z,Yi Q,Xia Y
Fri Dec 16 00:00:00 EST 2022
Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.
Autophagy
Gong Y,Tang N,Liu P,Sun Y,Lu S,Liu W,Tan L,Song C,Qiu X,Liao Y,Yu S,Liu X,Lin SH,Ding C
Fri Jul 01 00:00:00 EDT 2022
Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis.
International journal of biological sciences
Wang T,Lu Z,Han T,Wang Y,Gan M,Wang JB
Mon Jul 25 00:00:00 EDT 2022
Neferine Suppresses Experimental Colitis-Associated Colorectal Cancer by Inhibition of NF-[Formula: see text]B p65 and STAT3.
The American journal of Chinese medicine
Zhou Y,Xiang S,Zheng H,Hou Y,Wang Y,Li CC,Wu Q,Shi J,Chen X
Fri Aug 12 00:00:00 EDT 2022
Caveolin-1 negatively regulates inflammation and fibrosis in silicosis.
Journal of cellular and molecular medicine
He R,Yuan X,Lv X,Liu Q,Tao L,Meng J
Sat Jan 01 00:00:00 EST 2022
FGF15 Protects Septic Mice by Inhibiting Inflammation and Modulating Treg Responses.
Journal of inflammation research
Li X,Zhu Z,Xia Z,Xu B
Wed Mar 22 00:00:00 EDT 2023
Correlation Analysis of Umbilical Cord Blood Metabolic Phenotype and Inflammation in Patients with Gestational Diabetes Mellitus Complicated with Overweight and Obesity.
Evidence-based complementary and alternative medicine : eCAM
Chen Q,Li W,Deng Y,Li Y,Huang L,Zhao L,Li H
Sat Jul 16 00:00:00 EDT 2022
The critical role of B4GALT4 in promoting microtubule spindle assembly in HCC through the regulation of PLK1 and RHAMM expression.
Journal of cellular physiology
Dai Z,Wang K,Gao Y
Sat Jan 01 00:00:00 EST 2022
Mutations in GCK May Lead to MODY2 by Reducing Glycogen Synthesis.
Advanced biology
Li Z,Li K,Sun Y,Jiang X,Liu J,Li J,Fang L,Li G,Guan Q,Xu C
Tue Nov 01 00:00:00 EDT 2022
USP7 Promotes deubiquitination and stabilization of MyD88 to enhance immune responses.
Frontiers in immunology
Zhang N,Wang F,Zhang G,Zhang Q,Liu Y,Wang Q,Elsharkawy MS,Zheng M,Wen J,Zhao G,Li Q
Tue Aug 30 00:00:00 EDT 2022
IPO7 Promotes Odontoblastic Differentiation and Inhibits Osteoblastic Differentiation Through Regulation of RUNX2 Expression and Translocation.
Stem cells (Dayton, Ohio)
Zhang Y,Zhang H,Xiao Z,Yuan G,Yang G
Tue Nov 29 00:00:00 EST 2022
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
Phytotherapy research : PTR
Wu XY,Wang T,Hu HX,Zhang K,Zhao Y,Zhao BB,Lou HX,Wang XN,Shen T
Fri Apr 01 00:00:00 EDT 2022
Sorafenib attenuates liver fibrosis by triggering hepatic stellate cell ferroptosis via HIF-1α/SLC7A11 pathway.
Cell proliferation
Yuan S,Wei C,Liu G,Zhang L,Li J,Li L,Cai S,Fang L
Sat Jan 01 00:00:00 EST 2022
Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer.
Cell
Fu A,Yao B,Dong T,Chen Y,Yao J,Liu Y,Li H,Bai H,Liu X,Zhang Y,Wang C,Guo Y,Li N,Cai S
Thu Apr 14 00:00:00 EDT 2022
Functional characterization of human organic anion transporter 10 (OAT10/SLC22A13) as an orotate transporter.
Drug metabolism and pharmacokinetics
Shinoda Y,Yamashiro T,Hosooka A,Yasujima T,Yuasa H
Fri Apr 01 00:00:00 EDT 2022
Role and mechanism of the Dectin-1-mediated Syk/NF-κB signaling pathway in Talaromyces marneffei infection.
Experimental and therapeutic medicine
Peng Y,Chen Y,Ma J,Zhou W,Wang Y,Wang Y,Zheng H,Shi W
Sat Jan 01 00:00:00 EST 2022
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Cell biology and toxicology
Wang H,Ai J,Shopit A,Niu M,Ahmed N,Tesfaldet T,Tang Z,Li X,Jamalat Y,Chu P,Peng J,Ma X,Qaed E,Han G,Zhang W,Wang J,Tang Z
Wed Jun 01 00:00:00 EDT 2022
Anti-proliferation and anti-inflammation effects of corilagin in rheumatoid arthritis by downregulating NF-κB and MAPK signaling pathways.
Journal of ethnopharmacology
Shen Y,Teng L,Qu Y,Liu J,Zhu X,Chen S,Yang L,Huang Y,Song Q,Fu Q
Thu Feb 10 00:00:00 EST 2022
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
The EMBO journal
Shu Y,Hao Y,Feng J,Liu H,Li ST,Feng J,Jiang Z,Ye L,Zhou Y,Sun Y,Zhou Z,Wei H,Gao P,Zhang H,Sun L
Thu Dec 01 00:00:00 EST 2022
Flubendazole induces mitochondrial dysfunction and DRP1-mediated mitophagy by targeting EVA1A in breast cancer.
Cell death & disease
Zhen Y,Yuan Z,Zhang J,Chen Y,Fu Y,Liu Y,Fu L,Zhang L,Zhou XL
Tue Apr 19 00:00:00 EDT 2022
DECR1 directly activates HSL to promote lipolysis in cervical cancer cells.
Biochimica et biophysica acta. Molecular and cell biology of lipids
Zhou H,Zhang J,Yan Z,Qu M,Zhang G,Han J,Wang F,Sun K,Wang L,Yang X
Tue Mar 01 00:00:00 EST 2022
Inhibition of Mcl-1 Synergistically Enhances the Antileukemic Activity of Gilteritinib and MRX-2843 in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
Cells
Wu S,Edwards H,Wang D,Liu S,Qiao X,Carter J,Wang Y,Taub JW,Wang G,Ge Y
Sat Sep 03 00:00:00 EDT 2022
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules.
Signal transduction and targeted therapy
Zheng Y,Deng J,Han L,Zhuang MW,Xu Y,Zhang J,Nan ML,Xiao Y,Zhan P,Liu X,Gao C,Wang PH
Mon Jan 24 00:00:00 EST 2022
Effect of starvation and refeeding on reactive oxygen species, autophagy and oxidative stress in Chinese perch (Siniperca chuatsi) muscle growth.
Journal of fish biology
Wu P,Chen L,Cheng J,Pan Y,Zhu X,Chu W,Zhang J
Fri Jul 01 00:00:00 EDT 2022
Establishment of a pseudovirus neutralization assay based on SARS-CoV-2 S protein incorporated into lentiviral particles.
Biosafety and health
Wang S,Liu L,Wang C,Wang Z,Duan X,Chen G,Zhou H,Shao H
Tue Feb 01 00:00:00 EST 2022
Actin nucleator formins regulate the tension-buffering function of caveolin-1.
Journal of molecular cell biology
Shi X,Tang D,Xing Y,Zhao S,Fan C,Zhong J,Cui Y,Shi K,Jiu Y
Sat Jan 29 00:00:00 EST 2022
Comprehensive Analysis of Protein Acetylation and Glucose Metabolism in Mouse Brains Infected with Rabies Virus.
Journal of virology
Pei J,Yuan Y,Tian D,Huang F,Zhang C,Wang C,Zhou M,Chen H,Fu Z,Zhao L
Wed Feb 23 00:00:00 EST 2022
Zebrafish Xenograft Model for Studying Pancreatic Cancer-Instructed Innate Immune Microenvironment.
International journal of molecular sciences
Wang X,Li W,Jiang H,Ma C,Huang M,Wei X,Wang W,Jing L
Thu Jun 09 00:00:00 EDT 2022
Sunitinib induced hepatotoxicity in L02 cells via ROS-MAPKs signaling pathway.
Frontiers in pharmacology
Tang TL,Yang Y,Guo L,Xia S,Zhang B,Yan M
Fri Nov 18 00:00:00 EST 2022
Paeoniflorin attenuates monocrotaline-induced pulmonary arterial hypertension in rats by suppressing TAK1-MAPK/NF-κB pathways.
International journal of medical sciences
Yu M,Wu X,Wang J,He M,Han H,Hu S,Xu J,Yang M,Tan Q,Wang Y,Wang H,Xie W,Kong H
Thu May 19 00:00:00 EDT 2022
Inhibiting ALK-TOPK signaling pathway promotes cell apoptosis of ALK-positive NSCLC.
Cell death & disease
Xiao J,Zhang L,Yi H,Zou L,Mo J,Xue F,Zheng J,Huang Y,Lu H,Wu H,Xue P,Zhang X,He L,Li Z,Pang S,Qiao G,Duan Q,Zhu F
Tue Sep 27 00:00:00 EDT 2022
The ubiquitin-26S proteasome system and autophagy relay proteome homeostasis regulation during silique development.
The Plant journal : for cell and molecular biology
Yu P,Hua Z
Thu Sep 01 00:00:00 EDT 2022
Proteasomal deubiquitylase activity enhances cell surface recycling of the epidermal growth factor receptor in non-small cell lung cancer.
Cellular oncology (Dordrecht)
Wang S,Wang T,Yang Q,Cheng S,Liu F,Yang G,Wang F,Wang R,Yang D,Zhou M,Duan C,Zhang Y,Liu H,Dai Z,Tian K,Liu S
Sat Oct 01 00:00:00 EDT 2022
Bisdemethoxycurcumin Attenuated Renal Injury via Activation of Keap1/Nrf2 Pathway in High-Fat Diet-Fed Mice.
International journal of molecular sciences
Ding X,Chen Y,Zhou L,Wu R,Jian T,Lyu H,Liu Y,Chen J
Sat Jul 02 00:00:00 EDT 2022
Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway.
BMC pulmonary medicine
Li MY,Qin YQ,Tian YG,Li KC,Oliver BG,Liu XF,Zhao P,Li JS
Tue Nov 22 00:00:00 EST 2022
Metabolic Reprogramming of Microglia Enhances Proinflammatory Cytokine Release through EphA2/p38 MAPK Pathway in Alzheimer's Disease.
Journal of Alzheimer's disease : JAD
Ma X,Zhang Y,Gou D,Ma J,Du J,Wang C,Li S,Cui H
Tue Jul 26 00:00:00 EDT 2022
Norcantharidin Induces Immunogenic Cell Death of Bladder Cancer Cells through Promoting Autophagy in Acidic Culture.
International journal of molecular sciences
Xu L,Su B,Mo L,Zhao C,Zhao Z,Li H,Hu Z,Li J
Fri Apr 01 00:00:00 EDT 2022
Ellagic acid ameliorates paraquat-induced liver injury associated with improved gut microbial profile.
Environmental pollution (Barking, Essex : 1987)
Qi M,Wang N,Xiao Y,Deng Y,Zha A,Tan B,Wang J,Yin Y,Liao P
Sat Jan 15 00:00:00 EST 2022
Asiatic Acid Attenuates Osteoporotic Bone Loss in Ovariectomized Mice Through Inhibiting NF-kappaB/MAPK/ Protein Kinase B Signaling Pathway.
Frontiers in pharmacology
Dong M,Zeng J,Yang C,Qiu Y,Wang X
Sat Feb 26 00:00:00 EST 2022
The Effects of Intraoperative Hypothermia on Postoperative Cognitive Function in the Rat Hippocampus and Its Possible Mechanisms.
Brain sciences
Xu G,Li T,Huang Y
Wed Jan 12 00:00:00 EST 2022
(±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) Benzoate Protects Against Oxidative Stress Injury in PC12 Cells Exposed to H2O2 Through Activation of Nrf2 Pathway.
Frontiers in pharmacology
Qi S,Zhang X,Fu Z,Pi A,Shi F,Fan Y,Zhang J,Xiao T,Shang D,Lin M,Gao N,Chang J,Gao Y
Tue Aug 09 00:00:00 EDT 2022
Lycopene Improves Bone Quality and Regulates AGE/RAGE/NF-кB Signaling Pathway in High-Fat Diet-Induced Obese Mice.
Oxidative medicine and cellular longevity
Xia B,Zhu R,Zhang H,Chen B,Liu Y,Dai X,Ye Z,Zhao D,Mo F,Gao S,Wang XD,Bromme D,Wang L,Wang X,Zhang D
Thu Mar 17 00:00:00 EDT 2022
Structure and biological evaluation of Caenorhabditis elegans CISD-1/mitoNEET, a KLP-17 tail domain homologue, supports attenuation of paraquat-induced oxidative stress through a p38 MAPK-mediated antioxidant defense response.
Advances in redox research
Boos JR,Jandrain HN,Hagiuda E,Taguchi AT,Hasegawa K,Fedun BL,Taylor SJ,Elad SM,Faber SE,Kumasaka T,Iwasaki T,Geldenhuys WJ
Thu Dec 01 00:00:00 EST 2022
Sodium hydrosulfide reverses β2-microglobulin-induced depressive-like behaviors of male Sprague-Dawley rats: Involving improvement of synaptic plasticity and enhancement of Warburg effect in hippocampus.
Behavioural brain research
Yang SQ,Tang YY,Zeng D,Tian Q,Wei HJ,Wang CY,Zhang P,Chen YJ,Zou W,Tang XQ
Mon Jan 24 00:00:00 EST 2022
Salvianolic acid B alleviates diabetic endothelial and mitochondrial dysfunction by down-regulating apoptosis and mitophagy of endothelial cells.
Bioengineered
Xiang J,Zhang C,Di T,Chen L,Zhao W,Wei L,Zhou S,Wu X,Wang G,Zhang Y
Tue Feb 01 00:00:00 EST 2022
HDM induce airway epithelial cell ferroptosis and promote inflammation by activating ferritinophagy in asthma.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zeng Z,Huang H,Zhang J,Liu Y,Zhong W,Chen W,Lu Y,Qiao Y,Zhao H,Meng X,Zou F,Cai S,Dong H
Wed Jun 01 00:00:00 EDT 2022
Sestrin2 Overexpression Ameliorates Endoplasmic Reticulum Stress-Induced Apoptosis via Inhibiting mTOR Pathway in HepG2 Cells.
International journal of endocrinology
Hu H,Luo Z,Liu X,Huang L,Lu X,Ding R,Duan C,He Y
Thu Dec 22 00:00:00 EST 2022
Effect of 1-Deoxynojirimycin on insulin resistance in prediabetic mice based on next-generation sequencing and intestinal microbiota study.
Journal of ethnopharmacology
Ren X,Xing Y,He L,Xiu Z,Yang L,Han A,Jia Q,Dong Y
Tue May 10 00:00:00 EDT 2022
Genetic instability of lung induced by carbon black nanoparticles is related with Plk1 signals changes.
NanoImpact
Pei Z,Ning J,Zhang N,Zhang X,Zhang H,Zhang R
Fri Apr 01 00:00:00 EDT 2022
The inhibitory effect and mechanism of Yi-qi-hua-yu-jie-du decoction on the drug resistance of gastric cancer stem cells based on ABC transporters.
Chinese medicine
Huang W,Wen F,Gu P,Liu J,Xia Y,Li Y,Zhou J,Song S,Ruan S,Gu S,Chen X,Shu P
Tue Aug 09 00:00:00 EDT 2022
Neobavaisoflavone inhibits allergic inflammatory responses by suppressing mast cell activation.
International immunopharmacology
Liang R,Yuan Y,Bai Y,Liu X,Chen J,Jiang D,Meng D,Chen G,Li B,Zhou L,Guo W
Thu Sep 01 00:00:00 EDT 2022
Long noncoding RNA HOTAIR facilitates pulmonary vascular endothelial cell apoptosis via DNMT1 mediated hypermethylation of Bcl-2 promoter in COPD.
Respiratory research
Dai Z,Liu X,Zeng H,Chen Y
Sat Dec 17 00:00:00 EST 2022
Spinal 5-HT2A receptor is involved in electroacupuncture inhibition of chronic pain.
Molecular pain
Yuan XC,Wang YY,Tian LX,Yan XJ,Guo YX,Zhao YL,Baba SS,Jia H,Wang HS,Li M,Huo FQ
Tue Apr 12 00:00:00 EDT 2022
Targeting APLN/APJ restores blood-testis barrier and improves spermatogenesis in murine and human diabetic models.
Nature communications
Song K,Yang X,An G,Xia X,Zhao J,Xu X,Wan C,Liu T,Zheng Y,Ren S,Wang M,Chang G,Cronin SJF,Penninger JM,Jing T,Ou X,Rao S,Liu Z,Zhao XY
Mon Nov 28 00:00:00 EST 2022
4-Octyl itaconate suppresses the osteogenic response in aortic valvular interstitial cells via the Nrf2 pathway and alleviates aortic stenosis in mice with direct wire injury.
Free radical biology & medicine
Peng X,Su S,Zeng J,Xie K,Yang X,Xian G,Xiao Z,Zhu P,Zheng S,Xu D,Zeng Q
Mon Aug 01 00:00:00 EDT 2022
Pygo1 Regulates the Behavior of Human Non-Small-Cell Lung Cancer via the Wnt/β-Catenin Pathway.
Disease markers
Wen Y,Li Y,Yang B,Guo X,Lin L,Liang J,Zhang K,Li X,Jiang Z,Wang Y,Li Y,Wu X,Fan X,Li F,Yuan W
Mon Nov 28 00:00:00 EST 2022
miR-1297 inhibits osteosarcoma cell proliferation and growth by targeting CCND2.
American journal of cancer research
Jiang P,Mao L,Lei X,Luo C,Zhang Y,Zhong X,Yin Z,Xu X,Li D,Zheng Q
Tue Aug 16 00:00:00 EDT 2022
Lactobacillus plantarum RS-09 Induces M1-Type Macrophage Immunity Against Salmonella Typhimurium Challenge via the TLR2/NF-κB Signalling Pathway.
Frontiers in pharmacology
Zhao C,Chen H,Liang H,Zhao X,Tang W,Wei M,Li Y,Zhang J,Yu X,Chen G,Zhu H,Jiang L,Zhang X
Mon Jun 20 00:00:00 EDT 2022
CLDN4 promotes growth of acute myeloid leukemia cells via regulating AKT and ERK1/2 signaling.
Biochemical and biophysical research communications
Hao S,Yang C,Song P,Shi H,Zou Y,Chen M,Wu X,Yin Y,Yu Z,Zhu W,Li M
Sat Sep 03 00:00:00 EDT 2022
Iron deficiency exacerbates aortic medial degeneration by inducing excessive mitochondrial fission.
Food & function
Zhong X,Wu Q,Wang Z,Zhang M,Zheng S,Shi F,Chen Y,Che Y,Yuan S,Xing K
Mon Jul 18 00:00:00 EDT 2022
High expression of PTGES3 is an independent predictive poor prognostic biomarker and correlates with immune infiltrates in lung adenocarcinoma.
International immunopharmacology
Gao P,Zou K,Xiao L,Zhou H,Xu X,Zeng Z,Zhang W
Thu Sep 01 00:00:00 EDT 2022
Ginsenoside Rk1 regulates glutamine metabolism in hepatocellular carcinoma through inhibition of the ERK/c-Myc pathway.
Food & function
Lu H,Yin H,Qu L,Ma X,Fu R,Fan D
Mon Apr 04 00:00:00 EDT 2022
Long Non-coding Antisense RNA DDIT4-AS1 Regulates Meningitic Escherichia coli-Induced Neuroinflammation by Promoting DDIT4 mRNA Stability.
Molecular neurobiology
Yang B,Xu B,Yang R,Fu J,Li L,Huo D,Chen J,Yang X,Tan C,Chen H,Wang X
Tue Mar 01 00:00:00 EST 2022
Topical retinoic acid induces corneal strengthening by upregulating transglutaminase 2 in murine cornea.
Experimental eye research
Wu J,Wang J,Wang L,Huang Y
Sat Jan 01 00:00:00 EST 2022
Topical retinoic acid induces corneal strengthening by upregulating transglutaminase 2 in murine cornea.
Experimental eye research
Wu J,Wang J,Wang L,Huang Y
Sat Jan 01 00:00:00 EST 2022
Breaking the Iron Homeostasis: A "Trojan Horse" Self-Assembled Nanodrug Sensitizes Homologous Recombination Proficient Ovarian Cancer Cells to PARP Inhibition.
ACS nano
Li Y,Cen Y,Fang Y,Tang S,Li S,Ren Y,Zhang H,Lu W,Xu J
Tue Aug 23 00:00:00 EDT 2022
Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma.
Cell chemical biology
Wang P,Zhang T,Wang X,Xiao H,Li H,Zhou LL,Yang T,Wei B,Zhu Z,Zhou L,Yang S,Lu X,Zhang Y,Huang Y,Gan J,Yang CG
Thu Sep 15 00:00:00 EDT 2022
Melatonin Alleviates Oxidative Stress Induced by H2O2 in Porcine Trophectoderm Cells.
Antioxidants (Basel, Switzerland)
Fu Y,Chen Y,Jin Z,Gao H,Song G,Wang Q,Xu K
Wed May 25 00:00:00 EDT 2022
Oryzanol alleviates high fat and cholesterol diet-induced hypercholesterolemia associated with the modulation of the gut microbiota in hamsters.
Food & function
Yan S,Chen J,Zhu L,Guo T,Qin D,Hu Z,Han S,Wang J,Matias FB,Wen L,Luo F,Lin Q
Wed Apr 20 00:00:00 EDT 2022
Isoliquiritin Ameliorates Cisplatin-Induced Renal Proximal Tubular Cell Injury by Antagonizing Apoptosis, Oxidative Stress and Inflammation.
Frontiers in medicine
Pei Z,Wu M,Yu H,Long G,Gui Z,Li X,Chen H,Jia Z,Xia W
Tue May 03 00:00:00 EDT 2022
miR-17-5p Promotes Glucose Uptake of HTR8/SVneo Trophoblast Cells by Inhibiting TXNIP/NLRP3 Inflammasome Pathway.
Diabetes, metabolic syndrome and obesity : targets and therapy
Jiang Y,Wei L,Zhang H,Chen Y,Gao P,Zhang J,Zhou X,Zhu S,Du Y,Fang C,Li J,Feng L,He M,Wang S,Yu J
Tue Nov 08 00:00:00 EST 2022
Phosphorylation of guanosine monophosphate reductase triggers a GTP-dependent switch from pro- to anti-oncogenic function of EPHA4.
Cell chemical biology
Wolff DW,Deng Z,Bianchi-Smiraglia A,Foley CE,Han Z,Wang X,Shen S,Rosenberg MM,Moparthy S,Yun DH,Chen J,Baker BK,Roll MV,Magiera AJ,Li J,Hurley E,Feltri ML,Cox AO,Lee J,Furdui CM,Liu L,Bshara W,LaConte LEW,Kandel ES,Pasquale EB,Qu J,Hedstrom L,Nikiforov MA
Thu Jun 16 00:00:00 EDT 2022
High RAS-related protein Rab-7a (RAB7A) expression is a poor prognostic factor in pancreatic adenocarcinoma.
Scientific reports
Liu Q,Bai Y,Shi X,Guo D,Wang Y,Wang Y,Guo WZ,Zhang S
Wed Oct 19 00:00:00 EDT 2022
Adhesive, injectable, and ROS-responsive hybrid polyvinyl alcohol (PVA) hydrogel co-delivers metformin and fibroblast growth factor 21 (FGF21) for enhanced diabetic wound repair.
Frontiers in bioengineering and biotechnology
Zhu H,Xu J,Zhao M,Luo H,Lin M,Luo Y,Li Y,He H,Wu J
Tue Sep 20 00:00:00 EDT 2022
Gut microbiota-mediated metabolic restructuring aggravates emotional deficits after anesthesia/surgery in rats with preoperative stress.
Frontiers in immunology
Lei L,Ji M,Yang J,Chen S,Gu H,Yang JJ
Fri Aug 26 00:00:00 EDT 2022
Effect of Azelaic Acid on Psoriasis Progression Investigated Based on Phosphatidylinositol 3-Kinase (PI3K)/Protein Kinase B (AKT) Signaling Pathway.
Clinical, cosmetic and investigational dermatology
Li L,Lu H,Zhang Y,Li Q,Shi S,Liu Y
Fri Dec 02 00:00:00 EST 2022
Probiotic Bifidobacterium breve MCC1274 Mitigates Alzheimer's Disease-Related Pathologies in Wild-Type Mice.
Nutrients
Abdelhamid M,Zhou C,Jung CG,Michikawa M
Sun Jun 19 00:00:00 EDT 2022
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
The Journal of biological chemistry
Xu X,Arunagiri A,Haataja L,Alam M,Ji S,Qi L,Tsai B,Liu M,Arvan P
Sat Oct 01 00:00:00 EDT 2022
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
The Journal of biological chemistry
Xu X,Arunagiri A,Haataja L,Alam M,Ji S,Qi L,Tsai B,Liu M,Arvan P
Sat Oct 01 00:00:00 EDT 2022
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
The Journal of biological chemistry
Xu X,Arunagiri A,Haataja L,Alam M,Ji S,Qi L,Tsai B,Liu M,Arvan P
Sat Oct 01 00:00:00 EDT 2022
Proteasomal degradation of WT proinsulin in pancreatic beta cells.
The Journal of biological chemistry
Xu X,Arunagiri A,Haataja L,Alam M,Ji S,Qi L,Tsai B,Liu M,Arvan P
Sat Oct 01 00:00:00 EDT 2022
Mitochondrial Transplantation Promotes Remyelination and Long-Term Locomotion Recovery following Cerebral Ischemia.
Mediators of inflammation
Chen T,Zhu Y,Jia J,Meng H,Xu C,Xian P,Li Z,Tang Z,Wu Y,Liu Y
Wed Sep 28 00:00:00 EDT 2022
LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis.
Aging
Wang S,Duan J,Liao J,Wang Y,Xiao X,Li L,Liu Y,Gu H,Yang P,Fu D,Du J,Li X,Shao M
Tue Aug 30 00:00:00 EDT 2022
Role of Sleep Restriction in Daily Rhythms of Expression of Hypothalamic Core Clock Genes in Mice.
Current issues in molecular biology
Li W,Wang Z,Cao J,Dong Y,Chen Y
Tue Jan 25 00:00:00 EST 2022
Exosome-mediated delivery of RBP-J decoy oligodeoxynucleotides ameliorates hepatic fibrosis in mice.
Theranostics
He F,Li WN,Li XX,Yue KY,Duan JL,Ruan B,Liu JJ,Song P,Yue ZS,Tao KS,Wang L
Thu Apr 21 00:00:00 EDT 2022
DI-3-n-butylphthalide mitigates stress-induced cognitive deficits in mice through inhibition of NLRP3-Mediated neuroinflammation.
Neurobiology of stress
Chen X,He JL,Liu XT,Zhao N,Geng F,Zhu MM,Liu GP,Ren QG
Thu Sep 01 00:00:00 EDT 2022
Forsythiaside B ameliorates coagulopathies in a rat model of sepsis through inhibition of the formation of PAD4-dependent neutrophil extracellular traps.
Frontiers in pharmacology
He W,Xi Q,Cui H,Zhang P,Huang R,Wang T,Wang D
Tue Nov 22 00:00:00 EST 2022
Benzaldehyde Attenuates the Fifth Stage Larval Excretory-Secretory Product of Angiostrongylus cantonensis-Induced Injury in Mouse Astrocytes via Regulation of Endoplasmic Reticulum Stress and Oxidative Stress.
Biomolecules
Chen KY,Chen YJ,Cheng CJ,Jhan KY,Wang LC
Fri Jan 21 00:00:00 EST 2022
Syntenin Regulated by miR-216b Promotes Cancer Progression in Pancreatic Cancer.
Frontiers in oncology
Zu F,Chen H,Liu Q,Zang H,Li Z,Tan X
Wed Feb 16 00:00:00 EST 2022
Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1α Inhibition.
Frontiers in cardiovascular medicine
Osuru HP,Lavallee M,Thiele RH
Sat Aug 06 00:00:00 EDT 2022
Effect of Qingyangshen glycosides on social defeat mice model.
Journal of ethnopharmacology
Liu D,Wang J,Chang L,Zhu Q,Jiang N,Azhar M,Zeng G
Fri Jul 15 00:00:00 EDT 2022
Enterovirus A71 utilizes host cell lipid β-oxidation to promote its replication.
Frontiers in microbiology
Yang X,Chen J,Lu Z,Huang S,Zhang S,Cai J,Zhou Y,Cao G,Yu J,Qin Z,Zhao W,Zhang B,Zhu L
Wed Oct 19 00:00:00 EDT 2022
Integrative proteomics and m6A microarray analyses of the signatures induced by METTL3 reveals prognostically significant in gastric cancer by affecting cellular metabolism.
Frontiers in oncology
Peng G,Chen S,Zheng N,Tang Y,Su X,Wang J,Dong R,Wu D,Hu M,Zhao Y,Liu M,Wu H
Tue Dec 06 00:00:00 EST 2022
ADH1C Facilitates Cisplatin Resistance of Lung Adenocarcinoma Cells.
DNA and cell biology
Jiang F,Shen Q,Zhang F,Fu J,Hu L,Wang J,Zhou H,Chen J,Wang Y
Wed Jun 01 00:00:00 EDT 2022
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
International journal of biological sciences
Miao J,Zhao C,Tang K,Xiong X,Wu F,Xue W,Duan B,Zhang H,Jing X,Li W,Sun Y,Hou N,Huang C
Thu Apr 14 00:00:00 EDT 2022
COPS5 Conferred the Platinum Resistance in Epithelial Ovarian Cancer.
Current issues in molecular biology
Zhang H,Yan T,Zhong A,Guo L,Lu R
Thu Sep 01 00:00:00 EDT 2022
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
Molecular pharmaceutics
Yang X,Shang P,Ji J,Malichewe C,Yao Z,Liao J,Du D,Sun C,Wang L,Tang YJ,Guo X
Mon Jan 03 00:00:00 EST 2022
Ursolic Acid Ameliorates Spinal Cord Injury in Mice by Regulating Gut Microbiota and Metabolic Changes.
Frontiers in cellular neuroscience
Rong ZJ,Cai HH,Wang H,Liu GH,Zhang ZW,Chen M,Huang YL
Tue May 24 00:00:00 EDT 2022
Dual antioxidant activity and the related mechanisms of a novel pentapeptide GLP4 from the fermented mycelia of Ganoderma lingzhi.
Food & function
Huang P,Luo FJ,Ma YC,Wang SX,Huang J,Qin DD,Xue FF,Liu BY,Wu Q,Wang XL,Liu GQ
Tue Aug 30 00:00:00 EDT 2022
High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction.
EMBO reports
Yuan Y,Miao Y,Ren T,Huang F,Qian L,Chen X,Zuo Y,Zhang HG,He J,Qiao C,Du Q,Wu Q,Zhang W,Zhu C,Xu Y,Wu D,Shi W,Jiang J,Xu G,Zheng H
Wed Jan 05 00:00:00 EST 2022
Eupalinolide B attenuates lipopolysaccharide-induced acute lung injury through inhibition of NF-κB and MAPKs signaling by targeting TAK1 protein.
International immunopharmacology
Yang L,Chen H,Hu Q,Liu L,Yuan Y,Zhang C,Tang J,Shen X
Sat Oct 01 00:00:00 EDT 2022
Knockdown of ZBTB11 impedes R-loop elimination and increases the sensitivity to cisplatin by inhibiting DDX1 transcription in bladder cancer.
Cell proliferation
Chen L,Liu Z,Tang H,Zhou Z,Chen J,Ma Z,Deng M,Li X,Wu Y,Zheng L,Zhou L,Zheng X,Liu Z
Thu Dec 01 00:00:00 EST 2022
Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity.
Nucleic acids research
Wu S,Ge Y,Lin K,Liu Q,Zhou H,Hu Q,Zhao Y,He W,Ju Z
Fri Apr 22 00:00:00 EDT 2022
Therapy-resistant and -sensitive lncRNAs, SNHG1 and UBL7-AS1 promote glioblastoma cell proliferation.
Oxidative medicine and cellular longevity
Cao M,Ma R,Li H,Cui J,Zhang C,Zhao J
Mon Apr 04 00:00:00 EDT 2022
Effects of bicyclol on hepatic sinusoidal obstruction syndrome induced by Gynura segetum.
Journal of clinical laboratory analysis
Yao J,Wu J,Jia S,Shao J,Zhang X,Xu Z,Zhang H,Li H,Yao X
Thu Dec 01 00:00:00 EST 2022
PCDHB14 promotes ferroptosis and is a novel tumor suppressor in hepatocellular carcinoma.
Oncogene
Liu Y,Ouyang L,Mao C,Chen Y,Li T,Liu N,Wang Z,Lai W,Zhou Y,Cao Y,Liu S,Liang Y,Wang M,Liu S,Chen L,Shi Y,Xiao D,Tao Y
Fri Jul 01 00:00:00 EDT 2022
The E3 Ligase TRIM4 Facilitates SET Ubiquitin-Mediated Degradation to Enhance ER-α Action in Breast Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Han D,Wang L,Long L,Su P,Luo D,Zhang H,Li Z,Chen B,Zhao W,Zhang N,Wang X,Liang Y,Li Y,Hu G,Yang Q
Thu Sep 01 00:00:00 EDT 2022
Pdcd4 promotes lipid deposition by attenuating PPARα-mediated fatty acid oxidation in hepatocytes.
Molecular and cellular endocrinology
Du X,Osoro EK,Chen Q,Yan X,Gao D,Wu L,Ren J,Feng L,Wu N,Lu K,Yang X,Zhong B,Han Y,Zhang F,Li D,Lan X,Lu S
Tue Apr 05 00:00:00 EDT 2022
Inhibition of NEK7 Suppressed Hepatocellular Carcinoma Progression by Mediating Cancer Cell Pyroptosis.
Frontiers in oncology
Yan Z,Da Q,Li Z,Lin Q,Yi J,Su Y,Yu G,Ren Q,Liu X,Lin Z,Qu J,Yin W,Liu J
Tue Mar 01 00:00:00 EST 2022
Rifaximin protects against circadian rhythm disruption-induced cognitive impairment through preventing gut barrier damage and neuroinflammation.
Journal of neurochemistry
Meng D,Yang M,Hu L,Liu T,Zhang H,Sun X,Wang X,Chen Y,Jin Y,Liu R
Thu Dec 01 00:00:00 EST 2022
SULF2 enhances GDF15-SMAD axis to facilitate the initiation and progression of pancreatic cancer.
Cancer letters
He R,Shi J,Xu D,Yang J,Shen Y,Jiang YS,Tao L,Yang M,Fu X,Yang JY,Liu D,Huo Y,Shen X,Lu P,Niu N,Sun YW,Xue J,Liu W
Sun Jul 10 00:00:00 EDT 2022
Oridonin Delays Aging Through the AKT Signaling Pathway.
Frontiers in pharmacology
An Y,Zhu J,Wang X,Sun X,Luo C,Zhang Y,Ye Y,Li X,Abulizi A,Huang Z,Zhang H,Yang B,Xie Z
Sat Jul 16 00:00:00 EDT 2022
Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.
BMC cancer
Song J,Ruze R,Chen Y,Xu R,Yin X,Wang C,Xu Q,Zhao Y
Tue Aug 16 00:00:00 EDT 2022
Tumor Necrosis Factor-α-Induced Protein 8-Like 2 Fosters Tumor-Associated Microbiota to Promote the Development of Colorectal Cancer.
Cancer immunology research
Lou Y,Song M,Han M,Zhong J,Tian X,Ren Y,Song Y,Duan L,Zhao P,Song X,Zhang W,Chen YH,Wang H
Tue Mar 01 00:00:00 EST 2022
SORTING NEXIN2 proteins mediate stomatal movement and the response to drought stress by modulating trafficking and protein levels of the ABA exporter ABCG25.
The Plant journal : for cell and molecular biology
Liang C,Li C,Wu J,Zhao M,Chen D,Liu C,Chu J,Zhang W,Hwang I,Wang M
Wed Jun 01 00:00:00 EDT 2022
ITGB5 promotes innate radiation resistance in pancreatic adenocarcinoma by promoting DNA damage repair and the MEK/ERK signaling pathway.
Frontiers in oncology
Wen X,Chen S,Chen X,Qiu H,Wang W,Zhang N,Liu W,Wang T,Ding X,Zhang L
Wed Oct 19 00:00:00 EDT 2022
A virulence factor as a therapeutic: the probiotic Enterococcus faecium SF68 arginine deiminase inhibits innate immune signaling pathways.
Gut microbes
Ghazisaeedi F,Meens J,Hansche B,Maurischat S,Schwerk P,Goethe R,Wieler LH,Fulde M,Tedin K
Fri Aug 05 00:00:00 EDT 2022
LMOD1, an oncogene associated with Lauren classification, regulates the metastasis of gastric cancer cells through the FAK-AKT/mTOR pathway.
BMC cancer
Tan Y,Chen Q,Pan S,An W,Xu H,Xing Y,Zhang J
Sat Apr 30 00:00:00 EDT 2022
The function and mechanism of dopamine in the activation of CD4+ T cell.
Immunopharmacology and immunotoxicology
Shao Y,Dong Y,Wang W,Chen Z,Hao C,Yang Y,Zhang J
Wed Jun 01 00:00:00 EDT 2022
Antitumor Effects of Astaxanthin on Esophageal Squamous Cell Carcinoma by up-Regulation of PPARγ.
Nutrition and cancer
Cui L,Li Z,Xu F,Tian Y,Chen T,Li J,Guo Y,Lyu Q
Tue Apr 26 00:00:00 EDT 2022
Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis.
Oxidative medicine and cellular longevity
Gao S,Zhou L,Lu J,Fang Y,Wu H,Xu W,Pan Y,Wang J,Wang X,Zhang J,Shao A
Tue Apr 05 00:00:00 EDT 2022
Exosomes derived from M2 macrophages induce angiogenesis to promote wound healing.
Frontiers in molecular biosciences
Lyu L,Cai Y,Zhang G,Jing Z,Liang J,Zhang R,Dang X,Zhang C
Sat Oct 29 00:00:00 EDT 2022
Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism.
Gut
Sun X,He X,Zhang Y,Hosaka K,Andersson P,Wu J,Wu J,Jing X,Du Q,Hui X,Ding B,Guo Z,Hong A,Liu X,Wang Y,Ji Q,Beyaert R,Yang Y,Li Q,Cao Y
Sat Jan 01 00:00:00 EST 2022
MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes.
iScience
Ding DX,Wang Y,Yan W,Fu WN
Fri Mar 18 00:00:00 EDT 2022
Mitochondrial apolipoprotein A-I binding protein alleviates atherosclerosis by regulating mitophagy and macrophage polarization.
Cell communication and signaling : CCS
Duan M,Chen H,Yin L,Zhu X,Novák P,Lv Y,Zhao G,Yin K
Sat May 07 00:00:00 EDT 2022
Down-regulation of NR2B receptors contributes to the analgesic and antianxiety effects of enriched environment mediated by endocannabinoid system in the inflammatory pain mice.
Behavioural brain research
Jiang S,Zheng C,Wen G,Bu B,Zhao S,Xu X
Fri Oct 28 00:00:00 EDT 2022
The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling.
Nature immunology
Concepcion AR,Wagner LE,Zhu J,Tao AY,Yang J,Khodadadi-Jamayran A,Wang YH,Liu M,Rose RE,Jones DR,Coetzee WA,Yule DI,Feske S
Tue Feb 01 00:00:00 EST 2022
CCL20/CCR6 axis mediates macrophages to promote proliferation and migration of ESCs by blocking autophagic flux in endometriosis.
Stem cell research & therapy
Tan J,Xu T,Gou Y,Wang H,Liang Z,Cao Y,Wang H,Yu Y,Jiao N,Zhang Z
Fri Jul 15 00:00:00 EDT 2022
LPS Activated Macrophages Induced Hepatocyte Pyroptosis via P2X7R Activation of NLRP3 in Mice.
Iranian journal of immunology : IJI
Luo L,Fang Y,Yuan Q,Liao J,Zhang Z
Tue Mar 01 00:00:00 EST 2022
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Cell research
Zhang HG,Wang B,Yang Y,Liu X,Wang J,Xin N,Li S,Miao Y,Wu Q,Guo T,Yuan Y,Zuo Y,Chen X,Ren T,Dong C,Wang J,Ruan H,Sun M,Xu X,Zheng H
Sat Oct 01 00:00:00 EDT 2022
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Cell research
Zhang HG,Wang B,Yang Y,Liu X,Wang J,Xin N,Li S,Miao Y,Wu Q,Guo T,Yuan Y,Zuo Y,Chen X,Ren T,Dong C,Wang J,Ruan H,Sun M,Xu X,Zheng H
Sat Oct 01 00:00:00 EDT 2022
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Cell research
Zhang HG,Wang B,Yang Y,Liu X,Wang J,Xin N,Li S,Miao Y,Wu Q,Guo T,Yuan Y,Zuo Y,Chen X,Ren T,Dong C,Wang J,Ruan H,Sun M,Xu X,Zheng H
Sat Oct 01 00:00:00 EDT 2022
Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis.
Cell research
Zhang HG,Wang B,Yang Y,Liu X,Wang J,Xin N,Li S,Miao Y,Wu Q,Guo T,Yuan Y,Zuo Y,Chen X,Ren T,Dong C,Wang J,Ruan H,Sun M,Xu X,Zheng H
Sat Oct 01 00:00:00 EDT 2022
Maternal Prkce expression in mature oocytes is critical for the first cleavage facilitating maternal-to-zygotic transition in mouse early embryos.
Cell proliferation
Zhang S,Gong X,Zhou Y,Ma Q,Cai Q,Yang G,Guo X,Chen Y,Xu M,Zhu Y,Zeng Y,Zeng F
Wed Jun 01 00:00:00 EDT 2022
Discovery of cinnamamide-barbiturate hybrids as a novel class of Nrf2 activator against myocardial ischemia/reperfusion injury.
Bioorganic chemistry
Wei B,Zhang J,Li NN,Yang LH,Xu XL,Shi YY,Liu SH,Chen YJ
Fri Jul 01 00:00:00 EDT 2022
Pharmacologic inhibition of LAT1 predominantly suppresses transport of large neutral amino acids and downregulates global translation in cancer cells.
Journal of cellular and molecular medicine
Nishikubo K,Ohgaki R,Okanishi H,Okuda S,Xu M,Endou H,Kanai Y
Sat Oct 01 00:00:00 EDT 2022
Direct conversion of human umbilical cord mesenchymal stem cells into retinal pigment epithelial cells for treatment of retinal degeneration.
Cell death & disease
Zhu X,Chen Z,Wang L,Ou Q,Feng Z,Xiao H,Shen Q,Li Y,Jin C,Xu JY,Gao F,Wang J,Zhang J,Zhang J,Xu Z,Xu GT,Lu L,Tian H
Mon Sep 12 00:00:00 EDT 2022
A homogalacturonan from Lonicera japonica Thunb. disrupts angiogenesis via epidermal growth factor receptor and Delta-like 4 associated signaling.
Glycoconjugate journal
Liao W,Hu X,Du Z,Wang P,Ding K
Thu Dec 01 00:00:00 EST 2022
NPC1-regulated dynamic of clathrin-coated pits is essential for viral entry.
Science China. Life sciences
Li G,Su B,Fu P,Bai Y,Ding G,Li D,Wang J,Yang G,Chu B
Tue Feb 01 00:00:00 EST 2022
Cortisol Stimulates Local Progesterone Withdrawal Through Induction of AKR1C1 in Human Amnion Fibroblasts at Parturition.
Endocrinology
Lu JW,Lei WJ,Ling LJ,Wang LY,Lin YK,Zhang F,Li MD,Pan F,Wang WS,Sun K
Tue Oct 11 00:00:00 EDT 2022
Qingfei Tongluo Formula Mitigates Mycoplasma pneumoniae Infection via the PERK Signaling Pathway.
Disease markers
Liu X,Wang M,Kan Q,Lin Y,Jiang Z
Wed Aug 23 00:00:00 EDT 2023
Inhibition of nuclear deacetylase Sirtuin-1 induces mitochondrial acetylation and calcium overload leading to cell death.
Redox biology
Sun Y,Yang YM,Hu YY,Ouyang L,Sun ZH,Yin XF,Li N,He QY,Wang Y
Fri Jul 01 00:00:00 EDT 2022
c-Myc participates in high glucose-mediated endothelial inflammation via upregulation of IRAK1 expression in diabetic nephropathy.
Cellular signalling
Hou W,Lu L,Li X,Sun M,Zhu M,Miao C
Fri Apr 01 00:00:00 EDT 2022
lncRNA IGF2-AS Regulates Nucleotide Metabolism by Mediating HMGA1 to Promote Pyroptosis of Endothelial Progenitor Cells in Sepsis Patients.
Oxidative medicine and cellular longevity
Liang G,Zeng M,Gao M,Xing W,Jin X,Wang Q,Deng L,Ou H,He Z
Tue Mar 08 00:00:00 EST 2022
Silencing ATF3 Might Delay TBHP-Induced Intervertebral Disc Degeneration by Repressing NPC Ferroptosis, Apoptosis, and ECM Degradation.
Oxidative medicine and cellular longevity
Li Y,Pan D,Wang X,Huo Z,Wu X,Li J,Cao J,Xu H,Du L,Xu B
Fri Apr 29 00:00:00 EDT 2022
iTRAQ-derived quantitative proteomics uncovers the neuroprotective property of bexarotene in a mice model of cerebral ischemia-reperfusion injury.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Liu H,Wang H,Chen S,Liu S,Tian X,Dong Z,Xu L
Sun May 01 00:00:00 EDT 2022
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway.
Journal of cardiovascular translational research
Cheng L,Wang H,Maboh R,Mao G,Wu X,Chen H
Sat Oct 01 00:00:00 EDT 2022
Peroxidase-like Active Nanomedicine with Dual Glutathione Depletion Property to Restore Oxaliplatin Chemosensitivity and Promote Programmed Cell Death.
ACS nano
Wu F,Du Y,Yang J,Shao B,Mi Z,Yao Y,Cui Y,He F,Zhang Y,Yang P
Tue Mar 22 00:00:00 EDT 2022
Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability.
Cell communication and signaling : CCS
Yao R,Zhang M,Zhou J,Liu L,Zhang Y,Gao J,Xu K
Thu May 26 00:00:00 EDT 2022
DR1 Activation Inhibits the Proliferation of Vascular Smooth Muscle Cells through Increasing Endogenous H2S in Diabetes.
Aging and disease
Xi Y,Wen X,Zhang Y,Jiao L,Bai S,Shi S,Chang G,Wu R,Sun F,Hao J,Li H
Wed Jun 01 00:00:00 EDT 2022
Polystyrene Microplastics Postpone APAP-Induced Liver Injury through Impeding Macrophage Polarization.
Toxics
Liu J,Zhang L,Xu F,Meng S,Li H,Song Y
Fri Dec 16 00:00:00 EST 2022
Progesterone Induces Apoptosis and Steroidogenesis in Porcine Placental Trophoblasts.
Animals : an open access journal from MDPI
Liu Y,Ding H,Yang Y,Liu Y,Cao X,Feng T
Sat Oct 08 00:00:00 EDT 2022
Role of complement C1q/C3-CR3 signaling in brain injury after experimental intracerebral hemorrhage and the effect of minocycline treatment.
Frontiers in immunology
Zheng Y,Fan L,Xia S,Yang Q,Zhang Z,Chen H,Zeng H,Fu X,Peng Y,Xu C,Yu K,Liu F,Cao S
Tue Oct 04 00:00:00 EDT 2022
Exogenous Linoleic Acid Intervention Alters Hepatic Glucose Metabolism in an Avian Embryo Model.
Frontiers in physiology
Zhang X,Wu Q,Zheng W,Liu C,Huang L,Zuo X,Xiao W,Han X,Ye H,Wang W,Zhu Y,Yang L
Fri Mar 11 00:00:00 EST 2022
Oxidative phosphorylation regulates interleukin-10 production in regulatory B cells via the extracellular signal-related kinase pathway.
Immunology
Zhu Y,Zhang X,Xie S,Bao W,Chen J,Wu Q,Lai X,Liu L,Xiong S,Peng Y
Thu Dec 01 00:00:00 EST 2022
Srolo Bzhtang reduces inflammation and vascular remodeling via suppression of the MAPK/NF-κB signaling pathway in rats with pulmonary arterial hypertension.
Journal of ethnopharmacology
Chen T,Su S,Yang Z,Zhang D,Li Z,Lu D
Fri Oct 28 00:00:00 EDT 2022
Silk fibroin nanofibrous scaffolds incorporated with microRNA-222 loaded chitosan nanoparticles for enhanced neuronal differentiation of neural stem cells.
Carbohydrate polymers
Li Z,Meng Z,Zhao Z
Tue Feb 01 00:00:00 EST 2022
Microcystin-leucine arginine (MC-LR) induces mouse ovarian inflammation by promoting granulosa cells to produce inflammatory cytokine via activation of cGAS-STING signaling.
Toxicology letters
Liu K,Zhao X,Guo M,Zhu J,Li D,Ding J,Han X,Wu J
Fri Apr 01 00:00:00 EDT 2022
Schizosaccharomyces pombe Fzo1 is subjected to the ubiquitin-proteasome-mediated degradation during the stationary phase.
International microbiology : the official journal of the Spanish Society for Microbiology
Ahmad F,Zhang Y,Yin H,Luo Y,Huang Y
Sun May 01 00:00:00 EDT 2022
USP14 regulates cell cycle progression through deubiquitinating CDK1 in breast cancer.
Acta biochimica et biophysica Sinica
Liu Y,Xu J,Wang Y,Gan M,Hu Q,Wang J,Han T
Fri Nov 25 00:00:00 EST 2022
Platelet-rich plasma attenuates the severity of joint capsule fibrosis following post-traumatic joint contracture in rats.
Frontiers in bioengineering and biotechnology
Zhang Y,Wang Z,Zong C,Gu X,Fan S,Xu L,Cai B,Lu S
Thu Feb 02 00:00:00 EST 2023
Integrated analysis of tRNA-derived small RNAs in proliferative human aortic smooth muscle cells.
Cellular & molecular biology letters
Zhao JZ,Li QY,Lin JJ,Yang LY,Du MY,Wang Y,Liu KX,Jiang ZA,Li HH,Wang SF,Sun B,Mu SQ,Li B,Liu K,Gong M,Sun SG
Wed Jun 15 00:00:00 EDT 2022
Bone marrow-targetable Green Tea Catechin-Based Micellar Nanocomplex for synergistic therapy of Acute myeloid leukemia.
Journal of nanobiotechnology
Bae KH,Lai F,Mong J,Niibori-Nambu A,Chan KH,Her Z,Osato M,Tan MH,Chen Q,Kurisawa M
Wed Nov 16 00:00:00 EST 2022
Pemafibrate attenuates pulmonary fibrosis by inhibiting myofibroblast differentiation.
International immunopharmacology
Liu Y,Chen S,Yu L,Deng Y,Li D,Yu X,Chen D,Lu Y,Liu S,Chen R
Fri Jul 01 00:00:00 EDT 2022
Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang W,Rong G,Gu J,Fan C,Guo T,Jiang T,Deng W,Xie J,Su Z,Yu Q,Mai J,Zheng R,Chen X,Tang X,Zhang J
Tue Mar 01 00:00:00 EST 2022
Monitoring Protein Import into the Endoplasmic Reticulum in Living Cells with Proximity Labeling.
ACS chemical biology
Lyu Z,Sycks MM,Espinoza MF,Nguyen KK,Montoya MR,Galapate CM,Mei L,Genereux JC
Fri Jul 15 00:00:00 EDT 2022
Oleuropein ameliorated lung ischemia-reperfusion injury by inhibiting TLR4 signaling cascade in alveolar macrophages.
Transplant immunology
Xu Z,Sun X,Ding B,Zi M,Ma Y
Sat Oct 01 00:00:00 EDT 2022
Regulation of chromatin accessibility by hypoxia and HIF.
The Biochemical journal
Batie M,Frost J,Shakir D,Rocha S
Thu Mar 31 00:00:00 EDT 2022
Vascular restenosis reduction with platelet membrane coated nanoparticle directed M2 macrophage polarization.
iScience
Li F,Rong Z,Zhang R,Niu S,Di X,Ni L,Liu C
Fri Oct 21 00:00:00 EDT 2022
Knockdown of long noncoding RNA MIAT attenuates cigarette smoke-induced airway remodeling by downregulating miR-29c-3p-HIF3A axis.
Toxicology letters
Gu W,Wang L,Deng G,Gu X,Tang Z,Li S,Jin W,Yang J,Guo X,Li Q
Tue Mar 01 00:00:00 EST 2022
miR‑141 impairs mitochondrial function in cardiomyocytes subjected to hypoxia/reoxygenation by targeting Sirt1 and MFN2.
Experimental and therapeutic medicine
Zhang H,Wang Y,Wu K,Liu R,Wang H,Yao Y,Kvietys P,Rui T
Thu Dec 01 00:00:00 EST 2022
Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis.
EBioMedicine
Xu S,Yang X,Chen Q,Liu Z,Chen Y,Yao X,Xiao A,Tian J,Xie L,Zhou M,Hu Z,Zhu F,Xu X,Hou F,Nie J
Thu Dec 01 00:00:00 EST 2022
Pu-erh Tea Restored Circadian Rhythm Disruption by Regulating Tryptophan Metabolism.
Journal of agricultural and food chemistry
Hu S,Luo L,Bian X,Liu RH,Zhao S,Chen Y,Sun K,Jiang J,Liu Z,Zeng L
Wed May 11 00:00:00 EDT 2022
Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway.
The Science of the total environment
Zhou J,Zeng L,Zhang Y,Wang M,Li Y,Jia Y,Wu L,Su P
Tue Nov 15 00:00:00 EST 2022
Chk1 Inhibition Ameliorates Alzheimer's Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Hu W,Wang Z,Zhang H,Mahaman YAR,Huang F,Meng D,Zhou Y,Wang S,Jiang N,Xiong J,Westermarck J,Lu Y,Wang J,Wang X,Shentu Y,Liu R
Tue Mar 01 00:00:00 EST 2022
Knockdown of hnRNPA1 Promotes NSCLC Metastasis and EMT by Regulating Alternative Splicing of LAS1L exon 9.
Frontiers in oncology
Han P,Cao P,Yue J,Kong K,Hu S,Deng Y,Li L,Li F,Zhao B
Sat Jul 16 00:00:00 EDT 2022
LINC01119 negatively regulates osteogenic differentiation of mesenchymal stem cells via the Wnt pathway by targeting FZD4.
Stem cell research & therapy
Gao H,Dong H,Zheng J,Jiang X,Gong M,Hu L,He J,Wang Y
Sat Jan 29 00:00:00 EST 2022
NCOA4-Mediated Ferroptosis in Bronchial Epithelial Cells Promotes Macrophage M2 Polarization in COPD Emphysema.
International journal of chronic obstructive pulmonary disease
Liu J,Zhang Z,Yang Y,Di T,Wu Y,Bian T
Fri Apr 08 00:00:00 EDT 2022
Methionine deprivation inhibits glioma growth through downregulation of CTSL.
American journal of cancer research
Qian F,Xu H,Zhang Y,Li L,Yu R
Wed Dec 21 00:00:00 EST 2022
Resveratrol activates the SIRT1/PGC-1 pathway in mice to improve synaptic-related cognitive impairment after TBI.
Brain research
Yu D,Zhao XY,Meng QP,Teng D,Deng K,Lin N
Thu Dec 01 00:00:00 EST 2022
Pathogenic variants in TSC2 might cause premature ovarian insufficiency through activated mTOR induced hyperactivation of primordial follicles.
Fertility and sterility
Xu B,Li Z,Li S,Ke H,Zhang Q,Qin Y,Guo T
Thu Dec 01 00:00:00 EST 2022
Serpina3c deficiency induced necroptosis promotes non-alcoholic fatty liver disease through β-catenin/Foxo1/TLR4 signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Qian LL,Ji JJ,Jiang Y,Guo JQ,Wu Y,Yang Z,Ma GS,Yao YY
Sun May 01 00:00:00 EDT 2022
Abrogation of ARF6 in promoting erastin-induced ferroptosis and mitigating capecitabine resistance in gastric cancer cells.
Journal of gastrointestinal oncology
Geng D,Wu H
Wed Jun 01 00:00:00 EDT 2022
Xiaoyao powder improves endometrial receptivity via VEGFR-2-mediated angiogenesis through the activation of the JNK and P38 signaling pathways.
Journal of ethnopharmacology
He M,Li L,Wei X,Geng D,Jiang H,Xiangxiang G,Zhang Y,Du H
Mon Jan 10 00:00:00 EST 2022
A possible mechanism to the antidepressant-like effects of 20 (S)-protopanaxadiol based on its target protein 14-3-3 ζ.
Journal of ginseng research
Chen L,Li R,Chen F,Zhang H,Zhu Z,Xu S,Cheng Y,Zhao Y
Thu Sep 01 00:00:00 EDT 2022
Quantitative Proteomics Analysis Expands the Roles of Lysine β-Hydroxybutyrylation Pathway in Response to Environmental β-Hydroxybutyrate.
Oxidative medicine and cellular longevity
Hou W,Liu G,Ren X,Liu X,He L,Huang H
Thu Mar 24 00:00:00 EDT 2022
Upregulation of Klotho Aggravates Insulin Resistance in Gestational Diabetes Mellitus Trophoblast Cells.
Genetics research
Lin L,Wang X,Zhao W,Chen Y
Mon Nov 07 00:00:00 EST 2022
FBXL6 depletion restrains clear cell renal cell carcinoma progression.
Translational oncology
Yu Y,Yao W,Wang T,Xue W,Meng Y,Cai L,Jian W,Yu Y,Zhang C
Thu Dec 01 00:00:00 EST 2022
Expression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 - Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes.
Frontiers in medicine
Schlichtner S,Yasinska IM,Ruggiero S,Berger SM,Aliu N,Prunk M,Kos J,Meyer NH,Gibbs BF,Fasler-Kan E,Sumbayev VV
Tue Mar 01 00:00:00 EST 2022
Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1.
Nature communications
Chen ZP,Xu D,Wang L,Mao YX,Li Y,Cheng MT,Zhou CZ,Hou WT,Chen Y
Wed Jun 08 00:00:00 EDT 2022
The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine.
Frontiers in cell and developmental biology
Xiao Z,Liu S,Li Z,Cui J,Wang H,Wang Z,Ren Q,Xia L,Wang Z,Li Y
Tue Jul 26 00:00:00 EDT 2022
Gastrodin Ameliorates Cognitive Dysfunction in Vascular Dementia Rats by Suppressing Ferroptosis via the Regulation of the Nrf2/Keap1-GPx4 Signaling Pathway.
Molecules (Basel, Switzerland)
Li Y,Zhang E,Yang H,Chen Y,Tao L,Xu Y,Chen T,Shen X
Sat Sep 24 00:00:00 EDT 2022
Leonurine alleviates ferroptosis in cisplatin-induced acute kidney injury by activating the Nrf2 signalling pathway.
British journal of pharmacology
Hu J,Gu W,Ma N,Fan X,Ci X
Mon Aug 01 00:00:00 EDT 2022
Exosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts.
Cell death & disease
Wang D,Wang X,Song Y,Si M,Sun Y,Liu X,Cui S,Qu X,Yu X
Wed Apr 20 00:00:00 EDT 2022
Zinc-finger protein 750 mitigates malignant biological behavior of oral CSC-like cells enriched from parental CAL-27 cells.
Oncology letters
Xu C,Yang HL,Yang YK,Pan L,Chen HY
Sat Jan 01 00:00:00 EST 2022
OLFM4 depletion sensitizes gallbladder cancer cells to cisplatin through the ARL6IP1/caspase-3 axis.
Translational oncology
Lin Z,Yang S,Zhou Y,Hou Z,Li L,Meng M,Ge C,Zeng B,Lai J,Gao H,Zhao Y,Xie Y,He S,Tang W,Li R,Tan J,Wang W
Tue Feb 01 00:00:00 EST 2022
Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway.
Frontiers in pharmacology
Li Z,Geng J,Xie B,He J,Wang J,Peng L,Hu Y,Dai H,Wang C
Sat Apr 02 00:00:00 EDT 2022
Downregulated XBP-1 Rescues Cerebral Ischemia/Reperfusion Injury-Induced Pyroptosis via the NLRP3/Caspase-1/GSDMD Axis.
Mediators of inflammation
Zhang Y,Yao Z,Xiao Y,Zhang X,Liu J
Tue May 03 00:00:00 EDT 2022
Synthesis and biological evaluation of aminobenzamides containing purine moiety as class I histone deacetylases inhibitors.
Bioorganic & medicinal chemistry
Mao PT,He WB,Mai X,Feng LH,Li N,Liao YJ,Zhu CS,Li J,Chen T,Liu SH,Zhang QM,He L
Tue Feb 15 00:00:00 EST 2022
Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation.
Cell reports
Wang Y,Karki R,Mall R,Sharma BR,Kalathur RC,Lee S,Kancharana B,So M,Combs KL,Kanneganti TD
Tue Oct 04 00:00:00 EDT 2022
LPS induces pulmonary microvascular endothelial cell barrier dysfunction by upregulating ceramide production.
Cellular signalling
Jiang J,Ouyang H,Zhou Q,Tang S,Fang P,Xie G,Yang J,Sun G
Fri Apr 01 00:00:00 EDT 2022
SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease.
The Journal of clinical investigation
Li W,Feng W,Su X,Luo D,Li Z,Zhou Y,Zhu Y,Zhang M,Chen J,Liu B,Huang H
Tue Jan 04 00:00:00 EST 2022
Gegen Qinlian decoction ameliorates murine colitis by inhibiting the expansion of Enterobacteriaceae through activating PPAR-γ signaling.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu J,Tong Y,Shen Z,Li Y,Cheng C,Au R,Xu F,Liu Y,Zhu L,Shen H
Sat Oct 01 00:00:00 EDT 2022
Antisense oligonucleotides targeting the SMN2 promoter region enhance SMN2 expression in spinal muscular atrophy cell lines and mouse model.
Human molecular genetics
Wang J,Bai J,OuYang S,Wang H,Jin Y,Peng X,Ge X,Jiao H,Zou J,He C,Xiao P,Song F,Qu Y
Thu May 19 00:00:00 EDT 2022
Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae.
Life sciences
Liu M,Chen MY,An L,Ma SQ,Mei J,Huang WH,Zhang W
Tue Nov 01 00:00:00 EDT 2022
ROS-responsive nanoparticles for oral delivery of luteolin and targeted therapy of ulcerative colitis by regulating pathological microenvironment.
Materials today. Bio
Tan C,Fan H,Ding J,Han C,Guan Y,Zhu F,Wu H,Liu Y,Zhang W,Hou X,Tan S,Tang Q
Tue Mar 01 00:00:00 EST 2022
Ror2 mediates chronic post-thoracotomy pain by inducing the transformation of A1/A2 reactive astrocytes in rats.
Cellular signalling
Liu C,Shen L,Xu L,Zhu A,Huang Y
Sat Jan 01 00:00:00 EST 2022
Overexpression of CDCA8 Predicts Poor Prognosis and Promotes Tumor Cell Growth in Prostate Cancer.
Frontiers in oncology
Wan S,He Y,Zhang B,Yang Z,Du FM,Zhang CP,Fu YQ,Mi J
Sat Jul 16 00:00:00 EDT 2022
TRIM50 promotes NLRP3 inflammasome activation by directly inducing NLRP3 oligomerization.
EMBO reports
Lin Y,Lv X,Sun C,Sun Y,Yang M,Ma D,Jing W,Zhao Y,Cheng Y,Xuan H,Han L
Mon Nov 07 00:00:00 EST 2022
Novel Sphingosine Kinase 1 Inhibitor Suppresses Growth of Solid Tumor and Inhibits the Lung Metastasis of Triple-Negative Breast Cancer.
Journal of medicinal chemistry
Zhang S,Chen X,Wu C,Xu H,Xie X,Feng M,Hu S,Bai H,Gao F,Tong L,Ding J,Liu H,Xie Z,Wang J
Thu Jun 09 00:00:00 EDT 2022
The m6A-induced lncRNA CASC8 promotes proliferation and chemoresistance via upregulation of hnRNPL in esophageal squamous cell carcinoma.
International journal of biological sciences
Wu Q,Zhang H,Yang D,Min Q,Wang Y,Zhang W,Zhan Q
Mon Aug 22 00:00:00 EDT 2022
Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer.
Cell death and differentiation
Wang Y,Zheng L,Shang W,Yang Z,Li T,Liu F,Shao W,Lv L,Chai L,Qu L,Xu Q,Du J,Liang X,Zeng J,Jia J
Tue Nov 01 00:00:00 EDT 2022
METTL3 Regulates Liver Homeostasis, Hepatocyte Ploidy, and Circadian Rhythm-Controlled Gene Expression in Mice.
The American journal of pathology
Barajas JM,Lin CH,Sun HL,Alencastro F,Zhu AC,Aljuhani M,Navari L,Yilmaz SA,Yu L,Corps K,He C,Duncan AW,Ghoshal K
Sat Jan 01 00:00:00 EST 2022
The Protective Effect of Sulforaphane on Dextran Sulfate Sodium-Induced Colitis Depends on Gut Microbial and Nrf2-Related Mechanism.
Frontiers in nutrition
He C,Gao M,Zhang X,Lei P,Yang H,Qing Y,Zhang L
Sat Jul 16 00:00:00 EDT 2022
Inhibition of noncaspase proteases, calpain and proteasome, via ALLN and Bortezomib contributes to cell death through low degradation of pro-/anti-apoptotic proteins and apoptosis induction.
Medical oncology (Northwood, London, England)
Hamidi R,Ataei F,Hosseinkhani S
Sat Jun 18 00:00:00 EDT 2022
In Vitro and In Vivo Evaluation of Antidiabetic Properties and Mechanisms of Ficus tikoua Bur.
Nutrients
Wang H,Zhang K,Chen X,Han M,Lu J,Zhang Y
Thu Oct 20 00:00:00 EDT 2022
DNMT3B regulates proliferation of A549 cells through the microRNA-152-3p/NCAM1 pathway.
Oncology letters
Yang B,Huang S,Chen H,Li R,Hou S,Zhao J,Li Y
Sat Jan 01 00:00:00 EST 2022
Absence of TNF Leads to Alternative Activation in Peritoneal Macrophages in Experimental Listeria Monocytogenes Infection.
Immunological investigations
Li X,Chen C,Zhang L,Cheng X,Geng H,Ji Q,Li C,Chen H,Körner H,Liu X
Sun May 01 00:00:00 EDT 2022
Circ007071 Inhibits Unsaturated Fatty Acid Synthesis by Interacting with miR-103-5p to Enhance PPARγ Expression in the Dairy Goat Mammary Gland.
Journal of agricultural and food chemistry
Chen Z,Lu Q,Zhang X,Zhang Z,Cao X,Wang K,Lu X,Yang Z,Loor JJ,Jiao P
Wed Oct 26 00:00:00 EDT 2022
Sodium-glucose cotransporter-2 inhibitor alleviated atrial remodeling in STZ-induced diabetic rats by targeting TLR4 pathway.
Frontiers in cardiovascular medicine
Zhan X,Cheng L,Huo N,Yu L,Liu C,Liu T,Li G,Fu H
Sat Sep 24 00:00:00 EDT 2022
Berberine reduces hepatic ceramide levels to improve insulin resistance in HFD-fed mice by inhibiting HIF-2α.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Xia QS,Wu F,Wu WB,Dong H,Huang ZY,Xu L,Lu FE,Gong J
Wed Jun 01 00:00:00 EDT 2022
Remote cyclic compression ameliorates myocardial infarction injury in rats via AMPK-dependent pathway.
Microvascular research
Xu S,Xia X,Liu Y,Chen F,Gu R,Bian X,Xu X,Jia C,Lu S,Gu Y,Bai H,Zhang H
Sun May 01 00:00:00 EDT 2022
Pharmacological induction of AMFR increases functional EAAT2 oligomer levels and reduces epileptic seizures in mice.
JCI insight
Sha L,Li G,Zhang X,Lin Y,Qiu Y,Deng Y,Zhu W,Xu Q
Mon Aug 08 00:00:00 EDT 2022
Brown adipocytes promote epithelial mesenchymal transition of neuroblastoma cells by inducing PPAR-γ/UCP2 expression.
Adipocyte
Ge Z,Shang Y,Wang W,Yang J,Chen SZ
Thu Dec 01 00:00:00 EST 2022
Antibiotic pretreatment attenuates liver ischemia-reperfusion injury by Farnesoid X receptor activation.
Cell death & disease
Liu H,Wang J,Ding Y,Shi X,Ren H
Sat May 21 00:00:00 EDT 2022
Overexpression of VPS16 correlates with tumor progression and chemoresistance in colorectal cancer.
Biochemical and biophysical research communications
Zhang B,Ma Y,Niu H,Liu Z
Sat Jun 04 00:00:00 EDT 2022
The transcription factor KLF14 attenuates LPS-induced acute lung injury by ameliorating apoptosis of alveolar epithelial cells in mice.
Molecular immunology
Liu L,Yuan Y,Zhou Y,Yao L,Li J,Chen F
Thu Dec 01 00:00:00 EST 2022
lncRNA UCA1 induces autophagic gene expression via epigenetic regulation mediated by ATG16L1 and miR-132-3p in SH-SY5Y cells treated with retinoic acid.
Epileptic disorders : international epilepsy journal with videotape
Wen F,Zhan Q,Zou T,Tan ZG,Xiang J
Sat Oct 01 00:00:00 EDT 2022
Identified human breast milk compositions effectively inhibit SARS-CoV-2 and variants infection and replication.
iScience
Lai X,Yu Y,Xian W,Ye F,Ju X,Luo Y,Dong H,Zhou YH,Tan W,Zhuang H,Li T,Liu X,Ding Q,Xiang K
Fri Apr 15 00:00:00 EDT 2022
IL-1β induced by PRRSV co-infection inhibited CSFV C-strain proliferation via the TLR4/NF-κB/MAPK pathways and the NLRP3 inflammasome.
Veterinary microbiology
Chen D,Xu S,Jiang R,Guo Y,Yang X,Zhang Y,Zhou L,Ge X,Han J,Guo X,Yang H
Sat Oct 01 00:00:00 EDT 2022
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection.
Science immunology
Karki R,Lee S,Mall R,Pandian N,Wang Y,Sharma BR,Malireddi RS,Yang D,Trifkovic S,Steele JA,Connelly JP,Vishwanath G,Sasikala M,Reddy DN,Vogel P,Pruett-Miller SM,Webby R,Jonsson CB,Kanneganti TD
Fri Aug 26 00:00:00 EDT 2022