This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
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MA1-078 detects eIF2B3 in human, non-human primate and rat samples and has been successfully used in Western blot, ICC/IF, IHC (P) and immunoprecipitation applications.
The immunogen for MA1-078 is full length human eIF2B3 produced in HEK293T cells.
EIF2B3 catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutations in each of the five subunits of translation initiation factor eIF2B, including subunit 3, can cause leukoencephalopathy with vanishing white matter. EIF2B3 has also been identified as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: eIF-2B GDP-GTP exchange factor subunit gamma; eukaryotic translation initiation factor 2B, subunit 3 (gamma, 58kD); eukaryotic translation initiation factor 2B, subunit 3 gamma; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; Translation initiation factor eIF-2B subunit gamma
Gene Aliases: EIF-2B; EIF2B3; Eif2bg; EIF2Bgamma
Molecular Function: translation initiation factor