Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
JUP is a major cytoplasmic protein which is the only known constituent common to sub membranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat.
Protein Aliases: catenin (cadherin-associated protein), gamma 80kDa; Catenin gamma; Desmoplakin III; Desmoplakin-3; gamma-catenin; gamma-catenin (plakoglobin); Junction plakoglobin; OTTHUMP00000164735
Gene Aliases: ARVD12; CTNNG; D930025P04Rik; DP3; DPIII; JUP; PDGB; PG; PKGB