The red-fluorescent tetramethylrhodamine (TAMRA) alkyne can be reacted with azides via a copper-catalyzed click reaction. Click chemistry describes a classRead more
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Catalog number T10183
Price (USD)/ 0.5 mg
646.00
Add to cart
Quantity:
0.5 mg
Price (USD)/ 0.5 mg
646.00
Add to cart
The red-fluorescent tetramethylrhodamine (TAMRA) alkyne can be reacted with azides via a copper-catalyzed click reaction. Click chemistry describes a class of chemical reactions that use bio-orthogonal or biologically unique moities to label and detect a molecule of interest using a two-step procedure. The two-step reaction procedure involves a copper-catalyzed triazole formation of an azide and an alkyne. Click reactions have several characteristics: the reaction between the detection moieties is efficient; no extreme temperatures or solvents are required; the reaction product is stable; the components of the reaction are bioinert; and perhaps most importantly, no side reactions occur – the label and detection tags react selectively and specifically with one another. Unlike traditional chemical reactions utilizing succinimidyl esters or maleimides that target amines and sulfhydryls – functional groups that are not unique – click chemistry-labeled molecules can be applied to complex biological samples and be detected with unprecedented sensitivity due to extremely low background.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
FormatSolid
Quantity0.5 mg
Product TypeTetramethylrhodamine Alkyne
Molecular Weight (g/mol)467.53 Da
SolubilityDMSO (Dimethylsulfoxide)
Chemical ReactivityAzide
Detection MethodFluorescence
Reactive GroupAlkyne
Shipping ConditionRoom Temperature
Reactive MoietyAlkyne
Label or DyeTAMRA™ Isomers, TMR (Tetramethylrhodamine)
Label TypeClassic Dyes
ColorOrange
Product LineMolecular Probes™
Unit Size0.5 mg
Contents & Storage
Store at ≤-20°C, desiccated and protected from light.