Regulation of mitochondrial proteostasis by the proton gradient.
The EMBO journal
Patron M,Tarasenko D,Nolte H,Kroczek L,Ghosh M,Ohba Y,Lasarzewski Y,Ahmadi ZA,Cabrera-Orefice A,Eyiama A,Kellermann T,Rugarli EI,Brandt U,Meinecke M,Langer T
33-8200 was used in Immunocytochemistry-immunofluorescence to use a multiproteomic approach to demonstrate the regulation of the m-AAA protease AFG3L2 by the mitochondrial proton gradient, coupling mitochondrial protein turnover to the energetic status of mitochondria.
Tue Aug 16 00:00:00 EDT 2022
Enhancing Proteotoxic Stress in Leiomyosarcoma Cells Triggers Mitochondrial Dysfunctions, Cell Death, and Antitumor Activity in vivo.
Molecular cancer therapeutics
Iuliano L,Drioli S,Pignochino Y,Cafiero CM,Minisini M,D'Este F,Picco R,Dalla E,Giordano G,Grignani G,Di Giorgio E,Benedetti F,Felluga F,Brancolini C
33-8200 was used in Immunocytochemistry-immunoflourescence to evaluate the induction of proteotoxic stress as a possible strategy to kill leiomyosarcoma cells in a therapeutic perspective.
Tue Jun 01 00:00:00 EDT 2021
Degradation of altered mitochondria by autophagy is impaired in Lafora disease.
The FEBS journal
Lahuerta M,Aguado C,Sánchez-Martín P,Sanz P,Knecht E
33-8200 was used in Immunocytochemistry-immunoflourescence to show the autophagic degradation of altered mitochondria is impaired in LD, which is due to a partial defect in the autophagic response and not in the canonical mitophagy signalling pathways.
Fri Jun 01 00:00:00 EDT 2018
Intracellular glycolysis in brown adipose tissue is essential for optogenetically induced nonshivering thermogenesis in mice.
Jeong JH,Chang JS,Jo YH
Published figure using Cytochrome C monoclonal antibody (Product # 33-8200) in Western Blot
Fri Apr 27 00:00:00 EDT 2018
Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability.
Takaki T,Montagner M,Serres MP,Le Berre M,Russell M,Collinson L,Szuhai K,Howell M,Boulton SJ,Sahai E,Petronczki M
33-8200 was used in Immunocytochemistry-immunoflourescence to identify two subunits of the myosin phosphatase complex as proteins that safeguard nuclear integrity.
Mon Jul 24 00:00:00 EDT 2017
Loss of outer retinal neurons and circuitry alterations in the DBA/2J mouse.
Investigative ophthalmology & visual science
Fernández-Sánchez L,de Sevilla Müller LP,Brecha NC,Cuenca N
33-8200 was used in Immunohistochemistry to evaluate possible morphological changes in the outer retina of the DBA/2J mouse concomitant with disease progression and aging, based on the reduction of both the a- and b-waves and photopic flicker ERGs in this mouse line.
Tue Aug 12 00:00:00 EDT 2014
Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies.
Journal of neurochemistry
Trimmer PA,Borland MK,Keeney PM,Bennett JP,Parker WD
33-8200 was used in immunocytochemistry to report the generation of fibrillar and vesicular inclusions in a long-term cybrid cell culture model used to study Parkinson's disease.
Sun Feb 01 00:00:00 EST 2004
Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase.
Journal of cell science
Love DC,Kochan J,Cathey RL,Shin SH,Hanover JA,Kochran J
Sat Feb 15 00:00:00 EST 2003
Afferent regulation of cytochrome-c and active caspase-9 in the avian cochlear nucleus.
Wilkinson BL,Elam JS,Fadool DA,Hyson RL
33-8200 was used in immunohistochemistry (free floating) to study apoptosis of nucleus magnocellularis neurons.
Mon Nov 10 00:00:00 EST 2003
The Toxoplasma gondii protein ROP2 mediates host organelle association with the parasitophorous vacuole membrane.
The Journal of cell biology
Sinai AP,Joiner KA
Mon Jul 09 00:00:00 EDT 2001
Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis.
The Journal of biological chemistry
Nesterov A,Lu X,Johnson M,Miller GJ,Ivashchenko Y,Kraft AS
Fri Apr 06 00:00:00 EDT 2001