Invitrogen
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
Assay-dependent | - |
Flow Cytometry (Flow) |
1-1,000 ng/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG, kappa |
Class |
Recombinant Monoclonal |
Type |
Antibody |
Clone |
LynY507-5B6 |
Immunogen |
A synthetic phospho-peptide corresponding to residues surrounding Tyr507 of human phospho Lyn. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Protein A/G |
Storage buffer |
PBS with 0.10% BSA, 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells with exclusion in T lymphocytes. It has also been observed that Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling and Epithelial - Mesenchymal Transition (EMT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ26625; Lck/Yes-related novel protein tyrosine kinase; p53Lyn; p56Lyn; Tyrosine-protein kinase Lyn; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog
Gene Aliases: AA407514; Hck-2; JTK8; LYN; p53Lyn; p56Lyn
UniProt ID: (Human) P07948, (Mouse) P25911
Entrez Gene ID: (Human) 4067, (Mouse) 17096
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