Thermo Scientific™

Dionex™ ICS-5000+ Hybrid HPIC™ System

 Related applications:
Industrial Chromatography

Get best-in-class resolution, sensitivity, and throughput for even the most complex ICxIC (2D-IC) methods and trace level analyses. The versatile Thermo Scientific™ Dionex™ ICS-5000+ Hybrid HPIC™ System provides faster separations without compromising resolution, thanks to its dual high-pressure channels: one optimized for capillary flow rates, the other for standard (4mm) or microbore (2mm). You'll save time and improve reproducibility with precise, automatic eluent generation and sample preparation. Choose from a wide variety of chemistries, detectors, and automation options to fit your needs.

Error loading your content!

  Catalog number Price ({{currency}}) Availability Qty
also known as {{product.formattedSku}} 
{{product.availability.message}} Add To Cart

{{addItemToList.successMessage}} {{addItemToList.listName}}

Back to top


Built on our top-of-the-line IC platform, this system provides the high performance, convenience, and flexibility of the Thermo Scientific™ Dionex™ ICS-5000+ HPIC System with the power of parallel analytical and capillary channels.

Run two analyses concurrently on a single sample, analyze two samples, or perform advanced ICxIC (2D-IC) techniques. The Dionex ICS-5000+ Hybrid HPIC System is ideally suited for trace level determinations with high matrix concentrations, using a standard or microbore column in the first dimension to separate analytes from matrix, followed by a capillary separation in the second dimension. This method provides high sensitivity, enabling conductivity detection limits to rival those of mass spectrometry.

High Pressure, High Performance
  • Fast, sensitive separations without sacrificing resolution—up to two times faster still with Fast IC columns
  • Outstanding resolution using columns with small-diameter particles, thanks to high-pressure capability
  • Continuous operation at up to 5000psi when configured as a Reagent-Free™ IC (RFIC™) system
  • Optimized peak resolution with a choice of isocratic and electrolytic gradient separations on either channel, or optional quaternary low pressure gradients on the standard/microbore channel
  • Flexible support for standard bore (3-7mm I.D.)and microbore (1-3mm I.D.) columns on one channel and capillary columns (0.2-0.6mm I.D.) on the other
  • Wide variety of chemistries available in Thermo Scientific™ standard bore, microbore, capillary, and Fast IC columns
  • Flexible, easy to configure, modular design

The Capillary Advantage

The capillary channel in this hybrid system presents added advantages:

  • Always ready with 24/7 uptime and minimal calibration and equilibration time
  • Up to 18 months of continuous operation on one Eluent Generation cartridge
  • Small dead volumes for minimized peak dispersion and increased signal-to-noise ratio
  • Reduced eluent disposal costs—only 15mL/day for continuous operation at 10µL/min
  • Enhanced ease-of-use with Thermo Scientific™ Dionex™ IC Cube™ capillary consumable cartridges

Choose from a broad variety of Dionex ICS-5000+ modules and related products. See the Dionex ICS-5000+ HPIC System Product Features for a full list.

Sample Preparation and Automation Solutions

Dionex autosamplers integrate seamlessly with all Dionex ICS-5000+ HPIC systems, providing effortless automation and advanced sample preparation capabilities.

Need service or support?

Access our expert service team, information on support plans, parts and consumables resources, and other instrument services.  USA only [EN]


Applications Library Resource

The easy application note finder tool. Find the best solution to your separation challenges: easily download one-click workflows for use with Chromeleon CDS.

Go to AppsLab Library ›


Manuals & protocols