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MCAM (CD146) Recombinant Human Protein, hIgG1-Fc Tag

Catalog number: 10115H02H250

 Related applications: Protein Assays and Analysis

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Melanoma cell adhesion molecule (MCAM/CD146), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in cell biology research applications. It can also be used as a protein standard.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Gly 559) of human MCAM precursor (NP_006491.2) fused to the Fc region of human IgG1 at the C-terminus.

Activity: Measured by the ability of the immobilized protein to support the adhesion of the HUVEC human umbilical vein endothelial cell line . When 3 x 104 cells/well are added to human CD146 coated plates (0.8 µg/ml, 100 µl/well), approximately >30 % will adhere after one hour at 37°C.

Formulation: Lyophilized in PBS, pH 7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by Sino Biological Inc.

For Research Use Only. Not for use in diagnostic procedures.


Form: Lyophilized
Purity: ≥ 90% by SDS-PAGE
Gene ID: 4162
Species: Human
Expression: Mammalian
Gene Symbol: MCAM
Gene Aliases: MCAM, CD146, MUC18
Product Size: 5 x 50 µg
Protein Form: Truncated, Recombinant
Protein Family: CD Proteins
Endotoxin Level: < 1 EU/µg
Protein Subtype: Other Proteins
Molecular Weight: 86.4 kDa
Research Category: Immunology, Angiogenesis, Development, Extracellular Matrix & Cell Adhesion, Cardiovascular Research, Oncology, Signal Transduction
Protein Tag or Fusion: IgG1 Fc Tag
Validated Application: Assay Standard
Shipping Condition: Room Temperature

Contents & storage

Store at -20 to -70 °C


Manuals & protocols