See the new Lipofectamine® RNAiMAX Transfection Reagent protocol—now optimized for efficiency, viability and reproducibility

Lipofectamine™ RNAiMAX Transfection Reagent This product, and/or its packaging, incorporates one or more environmental/green features. Click on this icon to learn more.

Catalog number:  13778100

Related applications:


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Lipofectamine® RNAiMAX Transfection Reagent provides the highest transfection efficiencies on the widest variety of cell types for siRNA-mediated gene knockdown experiments. Lipofectamine® RNAiMAX is a proprietary RNAi-specific cationic lipid formulation designed specifically for the delivery of siRNA and miRNA into all cell types.

With Lipofectamine® RNAiMAX Transfection Reagent you will get:

• Superior transfection efficiency requiring lower RNAi concentrations, leading to more effective gene knockdown with minimal nonspecific effects
• Easy optimization due to minimal cytotoxicity across a 10-fold concentration range of transfection reagent
• Superior transfection efficiencies for miRNA antagonists and mimics
• Compatibility with a broad range of cell types, providing the most versatile approach to all of your gene silencing experiments
• A simple and rapid protocol for consistent and reproducible results

High knockdown in a wide range of cells
Lipofectamine® RNAiMAX Transfection Reagent transfects a wide range of cell types (see figure). For gene silencing, Lipofectamine® RNAiMAX Transfection Reagent's high-efficiency transfections lead to the high levels of gene knockdown needed to achieve convincing results.

Simple, high-throughput–ready transfections
Simply mix Lipofectamine® RNAiMAX Transfection Reagent with siRNA, add to your cells, incubate, and measure gene knockdown. The simplicity and speed combined with high transfection efficiency make Lipofectamine® RNAiMAX Transfection Reagent ideal for high-throughput siRNA transfections. Transfection conditions can be easily established for automated or robotic systems used in such applications.

Find an optimized Lipofectamine® RNAiMAX transfection protocol for your cell line.
For Research Use Only. Not for use in diagnostic procedures.


Cell Type: Established Cell Lines,Hard-to-Transfect Cells,Primary Cells,Stem Cells
Green Features: Sustainable packaging
High Throughput Compatibility: High Throughput-Compatible
Product Line: Lipofectamine®
Product Size: 0.1 mL
Sample Type (Specific): Synthetic siRNA
Serum Compatible: Yes
Shipping Condition: Approved for shipment at Room Temperature or on Wet Ice
Transfection Technique: Lipid-Based Transfection

Contents & storage

Each unit contains one vial of reagent. Store at 2–8°C. Lipofectamine® RNAiMAX™ Transfection Reagent is stable for 1 year when stored properly.