Thermo Scientific™

CaptureSelect™ TSH Affinity Matrix

Catalog number:  194356201L

Related applications:

Chromatography

Back to top

Description

CaptureSelect TSH Affinity Matrix was specifically designed for the purification of thyroid-stimulating hormone (TSH) from recombinant sources.

Main characteristics:

Matrix: agarose bead
Average particle size: 65 µm
Ligand: CaptureSelect TSH affinity ligand
Ligand coupling method: epoxide
Binding capacity: >5 mg/mL of resin
Elution conditions: 0.1 M citrate buffer, pH 3.0
Flow characteristics: 75–200 cm/h (up to 1 bar)
Formulation buffer: 20% (v/v) ethanol

Some features of CaptureSelect TSH Affinity Matrix include:
• Highly selective for thyroid-stimulating hormone with no affinity for the other gonadotropins (FSH, LH, and HCG)
• Enables efficient purification of recombinant TSH with high yields and retained activity
• Offers excellent scalability
• Non–animal-derived

The high selectivity and yields obtained using CaptureSelect TSH Affinity Matrix enable a robust and efficient purification process with excellent purity obtained in one step.

Free of animal components
CaptureSelect affinity ligands are created using a proprietary technology based on camelid-derived single-domain antibody fragments. The ligand is a 13 kDa fragment comprising the three complementarity determining regions (CDRs) that form the antigen binding domain. The ligand is efficiently produced by the yeast Saccharomyces cerevisiae in a production process free of animal components.

For Research Use or Further Manufacturing. Not for use in diagnostic procedures.

Specifications

Product Line: CaptureSelect™
Shipping Condition: Wet Ice
Format: Agarose Bead
Stationary Phase: CaptureSelect TSH Affinity Ligand

Contents & storage

Store in refrigerator (2–8°C).