This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• Ribavirin is a broad-spectrum antiviral nucleoside analog
• It inhibits viral genome synthesis
Applications
• Ribavirin is an antiviral compound
• Its metabolite, ribavirin 5'-phosphate, inhibits inosine monophosphate dehydrogenase (IMP), which is involved in GTP biosynthesis
RUO – Research Use Only
Literature References
Keppeke, G.D.; et al. IMP/GTP balance modulates cytoophidium assembly and IMPDH activity. Cell Div. 2018, 15,13:5.
Li, W.; Shen, F.; Weber, G.; Ribavirin and quercetin synergistically downregulate signal transduction and are cytotoxic in human ovarian carcinoma cells. Oncol Res. 1999, 11(5), 243-7.