Thermo Scientific™

ActivX™ TAMRA-FP Serine Hydrolase Probe

Catalog number: 88318
Thermo Scientific™

ActivX™ TAMRA-FP Serine Hydrolase Probe

Catalog number: 88318
Catalog Number
88318
Unit Size
6.8 µg
Price (USD)
Price: 534.00
Online price: 507.65
Your price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
883186.8 µg
Price: 534.00
Online price: 507.65
Your price:
-
Product Overview
Figures
Videos
Recommendations
Recommendations
Documents
FAQ
Citations & References
Additional Information
Recommendations

The TAMRA-FP probe feature a reactive fluorophosphonate group that is used to label and detect active serine hydrolases by fluorescent gel imaging, capillary electrophoresis or mass spectrometry. An anti-TAMRA antibody is also available for immuno-enrichment of TAMRA-FP probe-labeled proteins.

ActivX™ active-site enrichment probes are advantageous for determining active enzyme levels through the use of analog-tagged probes to allow profiling of both inactive and active enzymes. The ActivX probes selectively enrich only those enzymes that are functionally active and biologically relevant at the time of labeling. With selective enrichment, one can identify and profile target enzyme classes across samples or can assess the specificity and affinity of enzyme inhibitors.

The serine hydrolase superfamily is one of the largest, most diverse enzyme families in eukaryotic proteomes. Serine hydrolases are generally grouped into two large families: serine proteases (e.g., trypsin, elastase and thrombin) and metabolic serine hydrolases. Metabolic serine hydrolases are divided into multiple enzyme subclasses (e.g., esterases, lipases, amidases and peptidases) based on structure, catalytic mechanism and substrate preference. These probes can be used to assess activity or screen small molecule inhibitors against enzymes derived from cell lysates, subcellular fractions, tissues and recombinant proteins.

These products are subject to a limited use label license.

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Description
ActivX™ TAMRA-FP Serine Hydrolase Probe
Assay
Protein Quantitation Assay
Detection Method
Chemiluminescence, Mass Spectrometry, Western Blot
Substrate Type
Serine Hydrolase Substrate
Product Line
ActivX™
Quantity
6.8 μg
For Use With (Application)
Pull-Down
Target
Serine Hydrolase
Type
Fluorophosphonate (FP) probe
Label or Dye
Other Label(s) or Dye(s)
Format
Tube, Spin Column

Contents & Storage

Store at -80°C away from light. Stock solutions in DMSO can be stored at -20°C for 6 months.

Figures

Documents & Downloads

Certificates

    Frequently asked questions (FAQs)

    Citations & References

    Search citations by name, author, journal title or abstract text