The GeneChip™ Xenopus laevis Genome 2.0 Array can be used to study the whole genome of Xenopus laevis on a single array. The array is comprised of more than 32,400 probe sets representing more than 29,900 X. laevis transcripts, and was designed in close collaboration with the Xenopus research community as part of the GeneChip Consortia Program. Sequences used in the design of the array were selected from the X. laevis UniGene build 69 (July 2006) and GenBank™ mRNAs (through September 12, 2006).

X. laevis is one of the most important model organisms in developmental biology. Much of the current understanding of early embryonic development derives from experiments performed in the Xenopus embryo.

The GeneChip Xenopus laevis Genome 2.0 Array is designed specifically to monitor gene expression in X. laevis, providing significant utility in developmental studies, such as induction and over-expression. This array is especially useful for researchers interested in identifying the genetic mechanisms critical to the following processes:

• Primordial germ cell migration
• Oocyte maturation
• Programmed cell death
• Pluripotency and lineage specificity
• Nuclear transport
• Patterning events
• Chromosome replication
• Chromatin assembly
• Cell cycle progression
• Intracellular signaling
• Organogenesis
• Oncogenesis

Array Annotations (Interim File)
The GeneChip Xenopus laevis Genome 2.0 Array annotation file contains design-time annotations, using both the original probe-set names and new probe-set names. New probe-set names were assigned to differentiate the probe-set identifiers for GeneChip Xenopus laevis Genome 2.0 Array from the older, version-1.0 array. The new naming convention for the version 2.0 array contains the prefix 'Xl2' for all probe-set identifiers, while the original probe-set IDs contain the prefix 'Xl.'

Please see the Documents Section below for related Manuals, Annotation Files and Data Sheets.