Applied Biosystems™

GeneChip™ Mouse Gene 2.0 ST Array

Catalog number: 902119
Applied Biosystems™

GeneChip™ Mouse Gene 2.0 ST Array

Catalog number: 902119
Catalog Number
902119
Unit Size
30 arrays
Price (USD)
13,700.00
Your Price:
Availability
***
Quantity
Catalog Number
Unit Size
6 arrays
Price (USD)
2,730.00
Your Price:
Availability
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Quantity
Catalog Number
Unit Size
2 arrays
Price (USD)
914.00
Your Price:
Availability
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Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
90211930 arrays
13,700.00
Your Price:
***
9021186 arrays
2,730.00
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9025002 arrays
914.00
Your Price:
***
Product Overview
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The GeneChip™ Mouse Gene 2.0 ST Array is a whole-transcript array that includes probes to measure both messenger (mRNA) and long intergenic non-coding RNA transcripts (lincRNA). This whole-transcript array design provides a complete expression profile of mRNA as well as the intermediary lincRNA transcripts that impact the mRNA expression profile.

Since the design of the GeneChip Mouse Gene 1.0 ST Array, there has been a substantial increase in the structural and functional understanding of the mouse genome. This increase in knowledge includes the identification of a large number of long intergenic lincRNA that have been identified by the research community. In order to provide the research community with a tool that can measure the differential expression of this exciting class of RNA transcripts, we designed the GeneChip Mouse Gene 2.0 ST Array. To supplement the lincRNA data contained in RefSeq, we used sequence and transcript data from lncRNA db (http://lncrnadb.com/).

Comprehensive design
Research over the past 20 years has predominantly focused on protein-coding messenger RNA transcripts and their role in cellular processes, such as disease and development. Recently researchers have identified more that 2,000 transcripts (>200 bases) in the mouse genome with little or no protein coding potential. Only a small fraction of these non-coding RNAs has functional annotations to date. However, there is ample evidence that differential expression of lincRNAs plays an important role in the genesis and progression of disease and that aberrant expression of these molecules have also been linked to cancer. Recent advancements in transcriptome profiling provided evidence of the association of lincRNAs in diverse range of cellular functions:
• Regulation of mRNA transcription
• Regulation of mRNA post-transcriptional modifications
• Occlusion/recruitment of transcription factor binding
• Activation and transportation of transcription factors
• Interaction with accessory proteins
• Guide protein complexes to locations in the genome

Key benefits
• Comprehensive coverage provides the best opportunity to discover interesting biology
   - >28,000 coding transcripts
   - >7,000 non-coding (include ˜2,000) long intergenic non-coding transcripts
• Measure alternative splicing events/transcript variants with probes designed to maximize exon coverage
• Reproducible: Intra-lot correlation coefficient = 0.99
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Type
Mouse Gene 2.0 ST Array
Array
Transcriptome Profiling
Product Line
GeneChip™
Number of Arrays
30 arrays
Array Format
array cartridge
Species
Mouse

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