Used in the bromination of benzylic positions under sunlamp irradiation. Employed as chain transfer agent for radical polymerization of methacrylates. It can also be employed as brominating reagent of active hydrogen compounds.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Used in the bromination of benzylic positions under sunlamp irradiation. Employed as chain transfer agent for radical polymerization of methacrylates. It can also be employed as brominating reagent of active hydrogen compounds.
Solubility
Not miscible or difficult to mix in water.
Notes
Store away from oxidizing agents. Protect against electrostatic charges.
RUO – Research Use Only
L R Pohl.; R V Branchflower.; R J Highet.; J L Martin.; D S Nunn.; T J Monks.; J W George.; J A Hinson. The formation of diglutathionyl dithiocarbonate as a metabolite of chloroform, bromotrichloromethane, and carbon tetrachloride. Drug Metabolism and Disposition. 1981, 9, (4), 334-339.
I.Glenn Sipes.; Gopal Krishna.; James R. Gillette. Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: Role of cytochrome P-450. Life Sciences. 1977, 20, (9), 1541-1548.
Precursor of dichlorocarbene, which adds to double bonds under phase-transfer conditions to give cyclopropanes: Liebigs Ann. Chem., 297 (1990).
Bromine radical source. For use in the bromination of benzylic positions under sunlamp irradiation, see: J. Am. Chem. Soc., 82, 391 (1960); Synth. Commun., 6, 109 (1976).
Reacts with Hexamethylphosphorous triamide, A12571, to give the dichloromethylenephosphorane, which undergoes Wittig reaction with aldehydes to give 1,1-dichloroalkenes, giving better results than the CCl4/Ph3P combination: Tetrahedron Lett., 1237, 1239 (1977); Synthesis, 554 (1980).