Chloroiodomethane is used as an intermediate in pharmaceuticals, organic synthesis, agrochemicals and dyestuff. It is also useful in cyclopropanation (Simmon-Smith reaction), Mannich reaction, aminomethylation and in epoxidation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Chloroiodomethane is used as an intermediate in pharmaceuticals, organic synthesis, agrochemicals and dyestuff. It is also useful in cyclopropanation (Simmon-Smith reaction), Mannich reaction, aminomethylation and in epoxidation.
Solubility
Miscible with acetone, benzene, diethyl ether and alcohol.
Notes
It is incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only
Degennaro, L.; Fanelli, F.; Giovine, A.; Luisi, R. External Trapping of Halomethyllithium Enabled by Flow Microreactors. Adv. Synth. Catal. 2015, 357 (1), 21-27.
Ooki, A.; Nomura, D.; Nishino, S.; Kikuchi, T.; Yokouchi, Y. A global-scale map of isoprene and volatile organic iodine in surface seawater of the Arctic, Northwest Pacific, Indian, and Southern Oceans. J. Geophys. Res. Oceans 2015, 120 (6), 4108-4128.