ACMA (9-Amino-6-Chloro-2-Methoxyacridine)

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ACMA (9-amino-6-chloro-2-methoxyacridine) is a DNA intercalator that selective binds to poly (d(A-T)). Excitation of the ACMA-DNA complex (excitation/emission maxima ~419/483 nm) is possible with most UV-light sources, making it compatible for use with both shorter- and longer-wavelength dyes. ACMA also apparently binds to membranes in the energized state and becomes quenched if a pH gradient forms. It has been extensively employed to follow cation and anion movement across membranes and to study the proton-pumping activity of various membrane-bound ATPases.
For Research Use Only. Not for use in diagnostic procedures.


Excitation/Emission: 419⁄483
Shipping Condition: Room Temperature
Sub Cellular Localization: Nucleus, Cell Membranes & Lipids
Detection Method: Fluorescent
For Use With (Equipment): Fluorescence Microscope
Color: Blue

Contents & storage

Store at room temperature and protect from light.