4-(Trifluoromethyl)benzoic acid, 98+%, Thermo Scientific Chemicals
4-(Trifluoromethyl)benzoic acid, 98+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

4-(Trifluoromethyl)benzoic acid, 98+%, Thermo Scientific Chemicals

Have Questions?
Change viewbuttonViewtableView
Quantity:
25 g
5 g
Catalog number A14494.14
also known as A14494-14
Price (USD)/ Each
192.00
-
Add to cart
Quantity:
25 g
Request bulk or custom format
Price (USD)/ Each
192.00
Add to cart
4-(Trifluoromethyl)benzoic acid, 98+%, Thermo Scientific Chemicals
Catalog numberA14494.14
Price (USD)/ Each
192.00
-
Add to cart
Chemical Identifiers
CAS455-24-3
IUPAC Name4-(trifluoromethyl)benzoic acid
Molecular FormulaC8H5F3O2
InChI KeySWKPKONEIZGROQ-UHFFFAOYSA-N
SMILESOC(=O)C1=CC=C(C=C1)C(F)(F)F
View more
SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White
Assay (Aqueous acid-base Titration)≥98.0 to ≤102.0%
Assay (Silylated GC)≥98.0%
Melting Point (clear melt)218.0-225.0?C
FormPowder or lumps
4-(Trifluoromethyl)benzoic acid was used in the synthesis of salicylanilide 4-(trifluoromethyl)benzoates via N,N?-dicyclohexylcarbodiimide coupling in dry N,N-dimethylformamide. It was used as internal standard during the ultra trace analysis of fluorinated aromatic carboxylic acids by GC/MS method.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-(Trifluoromethyl)benzoic acid was used in the synthesis of salicylanilide 4-(trifluoromethyl)benzoates via N,N′-dicyclohexylcarbodiimide coupling in dry N,N-dimethylformamide. It was used as internal standard during the ultra trace analysis of fluorinated aromatic carboxylic acids by GC/MS method.

Solubility
Soluble in water.

Notes
Store in cool, dry conditions in a well sealed container. Store away from oxidizing agents.
RUO – Research Use Only

General References:

  1. Andrew W. Nicholls; Kazuki Akira; John C. Lindon; R. Duncan Farrant; Ian D. Wilson; John Harding; David A. Killick; and Jeremy K. Nicholson. NMR Spectroscopic and Theoretical Chemistry Studies on the Internal Acyl Migration Reactions of the 1-O-Acyl-β-d-glucopyranuronate Conjugates of 2-, 3-, and 4-(Trifluoromethyl)benzoic Acids. Chem. Res. Toxicol. 1996, 9 (8), 1414-1424.
  2. C. U. Galdiga; Tyge Greibrokk. Ultra trace determination of fluorinated aromatic carboxylic acids in aqueous reservoir fluids by solid phase extraction in combination with negative ion chemical ionisation mass spectrometry after derivatisation with pentafluorobenzyl bromide. Fresenius' Journal of Analytical Chemistry. 1998, 361 (8), 797-802.