Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
POROS CaptureSelect KappaXL Affinity HPLC columns incorporate the advantages of high-speed POROS chromatography resins with the unique selectivity of CaptureSelect affinity ligands. CaptureSelect KappaXL Affinity HPLC columns recognize the Kappa light chain of human immumoglobulin, enabling quantitation and small-scale purification of all immunoglobulins (including IgA, IgM, IgD, IgE), Fab fragments, and bi-specific antibodies containing the Kappa light chain.
Analytical groups supporting biologic drug development require rapid, sensitive, and precise methods for protein quantitation from cell culture, fermentation harvests, or purification intermediates. It is critical for biopharmaceutical manufacturers to be able to monitor bioreactor product titers to determine when to harvest or abort a reactor cycle.
Features of POROS CaptureSelect KappaXL Affinity HPLC columns include:
High speed with high specificity
Automation
POROS Affinity HPLC columns are for use with HPLC systems, which allows the automation of chromatography methods, data collection, and data analysis. In addition, the immobilized affinity ligand enables one method and buffer system to be used across a class of molecules, streamlining analytical approaches.
Multiple cycles
Proper sample preparation, adherence to column operating instructions, and the use of an optimized column cleaning regimen results in strong re-use performance. POROS Affinity HPLC columns can be cycled hundreds of times for cost-effective and reproducible quantitation or purification.
Main characteristics