Phosphoenolpyruvic acid monopotassium salt is used in glycolysis and gluconeogeneis. It is used for regeneration of ATP from ADP in enzyme-catalyzed syntheses. It is metabolized by an enzyme namely pyruvate kinase to yield pyruvate. It acts as protection against cell injury induced by oxidative stress and against dysfunction in carbohydrate metabolism.
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Applications
Phosphoenolpyruvic acid monopotassium salt is used in glycolysis and gluconeogeneis. It is used for regeneration of ATP from ADP in enzyme-catalyzed syntheses. It is metabolized by an enzyme namely pyruvate kinase to yield pyruvate. It acts as protection against cell injury induced by oxidative stress and against dysfunction in carbohydrate metabolism.
Solubility
Soluble in water. Slightly soluble in methanol.
Notes
Hygroscopic. Incompatible with strong oxidizing agents.
RUO – Research Use Only
Used for regeneration of ATP from ADP in enzyme-catalyzed syntheses: J. Org. Chem., 47, 3765 (1982); 50, 1076 (1985); J. Am. Chem. Soc., 107, 7019 (1985).
Yarman, A.; Schulz, C.; Sygmund, C.; Ludwig, R.; Gorton, L.; Wollenberger, U.; Scheller, F. W. Third Generation ATP Sensor with Enzymatic Analyte Recycling. Electroanalysis 2014, 26 (9), 2043-2048.
Gauss, D.; Schoenenberger, B.; Wohlgemuth, R. Chemical and enzymatic methodologies for the synthesis of enantiomerically pure glyceraldehyde 3-phosphates. Carbohydr. Res. 2014, 389, 18-24.