1-Adamantanamine acts as a catalyst in enantioselective strecker reaction of phosphinoyl imines. It is also useful for making adamantane derivatives, i.e. amantadine hydrochloride. It is used in the pharmaceutical industry as antiviral and an antiparkinsonian drug.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-Adamantanamine acts as a catalyst in enantioselective strecker reaction of phosphinoyl imines. It is also useful for making adamantane derivatives, i.e. amantadine hydrochloride. It is used in the pharmaceutical industry as antiviral and an antiparkinsonian drug.
Solubility
Soluble in organic solvents. Insoluble in water.
Notes
Use only in a chemical fume hood. Keep away from sources of ignition. Incompatible with oxidizing agent.
RUO – Research Use Only
Yang, H.; Liu, Y.; Yang, L.; Liu, K.; Wang, Z.; Zhang, X. Cucurbit[7]uril as a “protective agent”: controlling photochemistry and detecting 1-adamantanamine. Chem. Commun. 2013, 49, 3905-3907.
Bose, A.; Das, J. K.; Das, N. Pore modification of deca-dodecasil-rhombohedral zeolite membrane by carbon loading from in situ decomposition of 1-adamantanamine for improved gas separation. RSC Adv. 2015, 5, , 67195-67205.