HEP10, Pooled Human Cryopreserved Hepatocytes

Catalog number: HMCS10

Gibco™  Related applications: Hepatocytes & Hepatic Models | Pharma & Biopharma | Primary Cell Culture | Target-Based ADME⁄Tox Assays

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Get the convenience, affordability, and power of a pooled population of hepatocytes in a single vial. HEP10™ Pooled Human Hepatocytes are a representative population of 10 different donor hepatocytes that have been isolated using our novel patent-pending CellStream Isolation Technology™, helping to deliver consistent, predictable results in your drug metabolism studies and other biological assays.

• Pure, highly viable hepatocytes isolated using our CellStream Isolation Technology™
• 10 donor hepatocytes, 5 male and 5 female in each vial
• Verified enzymatic and pathway activity

CellStream™ Isolation Technology
HEP10™ Pooled Human Hepatocytes are made using our novel patent-pending CellStream Isolation Technology™. This process eliminates the disadvantages of density gradient fractionation prior to cryopreservation of the pool. Instead, we gently isolate and purify the pre-screened, high-viability, and metabolically-active hepatocytes from other cells and debris. The result is a remarkably pure pooled hepatocyte preparation with high viability for use in drug metabolism studies and other biological assays.

10 Donors in One Vial
Each vial of HEP10™ Pooled Human Hepatocytes contains hepatocytes from ten individual donors, 5 female and 5 male donors. Custom HEP10 lots can also be prepared from our broad array of high-quality, single-donor cells. Large lots are also available for extensive studies.

Verified Activity
Each pool is characterized for CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A4⁄5, FMO activity, and NTCP, OATP1B3, and OATP transporter pathways.

Ready for Your Drug Metabolism Experiments
HEP10™ Pooled Human Hepatocytes are useful in a wide variety of applications, including intrinsic clearance, transport, toxicology, biochemistry and cell biology studies.,

These products require shipment in LN2 vapor dewars therefore additional fees may apply.
For Research Use Only. Not for use in diagnostic procedures.


Form: Cryopreserved
Format: Tube(s)
Species: Human
Cell Type: Hepatocytes
Culture Type: Suspension Cell Culture
Donor Source: Pooled
Product Size: 1.5 mL
Number of Cells: 4-8 x 106
Cell Passage Number: Passage 0

Contents & storage

Vials of cryopreserved hepatocytes should be stored in a cryostorage dewar or -135°C freezer.


Manuals & protocols

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