Ethyl chloroformate is used as derivatization reagent to investigate stereochemical conversion of chiral non-steroidal anti-inflammatory drugs during derivatization reaction. It is also used with ammonia and cyanuric chloride to convert carboxylic acids to nitriles. It is used to develop flexible template strategy for the generation of nanometer-scale templates via dip-pen nanolithography.
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Applications
Ethyl chloroformate is used as derivatization reagent to investigate stereochemical conversion of chiral non-steroidal anti-inflammatory drugs during derivatization reaction. It is also used with ammonia and cyanuric chloride to convert carboxylic acids to nitriles. It is used to develop flexible template strategy for the generation of nanometer-scale templates via dip-pen nanolithography.
Solubility
Not miscible in water.
Notes
Protect from heat. Store away from moisture and oxidizing agents. Store under dry inert gas. Refrigerate. Incompatible with heat, moisture and oxidizing agents.
RUO – Research Use Only
M R Wright; F Jamali. Limited extent of stereochemical conversion of chiral non-steroidal anti-inflammatory drugs induced by derivatization methods employing ethyl chloroformate.Journal of Chromatography B: Biomedical Sciences and Applications.1993,616 (1), 59-65.
Melanie Junge; Helmut Huegel; Philip J Marriott. Enantiomeric analysis of amino acids by using comprehensive two-dimensional gas chromatography.Chirality.2007,19 (3), 228-234.