Thermo Scientific™

Lab Vision™ Heat Shock Protein 70 (HSP70) Ab-2, Mouse Monoclonal Antibody

Related applications:

Anatomical Pathology

Obtain accurate, reproducible results in immunohistochemistry, western blotting, immunofluorescence, immunoprecipitation and flow cytometry experiments with Thermo Scientific™ Heat Shock Protein 70 (HSP70) Ab-2, Mouse Monoclonal Antibody.
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Heat shock proteins (HSP's) or stress response proteins (SRP's) are synthesized in variety of environmental and pathophysiological stressful conditions. Many HSP's are involved in processes such as protein denaturation-renaturation, folding-unfolding, transport-translocation, activation-inactivation, and secretion. HSP70 is found to be associated with steroid receptors, actin, p53, polyoma T antigen, nucleotides, and other unknown proteins. Also, HSP70 has been shown to be involved in protective roles against thermal stress, cytotoxic drugs, and other damaging conditions.

Host Species: Mouse

Clone: W27

Isotype: IgG2a

Species Reactivity: Human, Monkey and Cow. Others not known.

Epitope: Not determined

Immunogen: HSP70 protein from HeLa cells

Molecular Weight: 73 kDa (constitutive), 72 kDa (inducible)

Positive Control: BT474 or HeLa cells, Breast CA

Cellular Localization: Nuclear and cytoplasmic

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Flow Cytometry


USA: RUO; Int'l: RUO

General References:

1. Welch W J, et al. (1986) J Cell Biol, 103:2035-2052.

2. Welch W J, et al. (1985) Mol Cell Biol,5:1229-1237.