Thermo Scientific™

Lab Vision™ Insulin Receptor (β -Subunit) Ab-6, Mouse Monoclonal Antibody

Related applications:

Anatomical Pathology

Recommended for a variety molecular biology techniques, Thermo Scientific™ Insulin Receptor (β-Subunit) Ab-6, Mouse Monoclonal Antibody provides accurate, reproducible results.
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The human insulin receptor is a heterotetrameric membrane glycoprotein consisting of disulfide-linked subunits in a Β-α-α-Β configuration. The Β-subunit (95kDa) possesses a single transmembrane domain with tyrosine kinase acivity, whereas the α-subunit (135kDa) is completely extracellular.

Host Species: Mouse

Clone: CT-3

Isotype: IgG1

Species Reactivity: Human, Monkey, Mouse and Rat. Others not known.

Epitope: C-terminal

Immunogen: Recombinant fragment including the C-terminal 100 amino acids of human insulin receptor

Molecular Weight: 95kDa

Positive Control: HEP-G-2, IM-9 lymphocyte cells; Placenta or brain

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunoprecipitation (Not suitable)
  • Affinity Purification (With peptide elution)
  • ELISA (As capture antibody only)
  • Tyrosine Kinase Assay (Ab-mediated capture on microplates)

Note:

USA: RUO; Int'l: RUO