Thermo Scientific™

Lab Vision™ Calretinin, Rabbit Polyclonal Antibody

 Related applications:
Anatomical Pathology

Stain formalin-fixed, paraffin-embedded tissues using Thermo Scientific™ Calretinin, Rabbit Polyclonal Antibody, one marker in a comprehensive antibody portfolio that addresses all major disease states, ensuring the ideal tests are always available.

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Description

Calretinin is an intracellular calcium-binding protein belonging to the troponin C superfamily characterized by a structural motif described as the EF-hand domain. The immunohistochemical detection of calretinin in developing cerebellum is restricted to the later stages indicated by weak staining from week 21 of gestation, in Purkinje and basket cells and in neurons of the dentate nucleus. The intensity of staining increases as the cerebellum matures. In tumors, calretinin has been detected in mesotheliomas and some pulmonary adenocarcinomas.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse and Rat. Others not tested.

Epitope: Not determined

Immunogen: Recombinant full-length mouse calretinin protein

Molecular Weight: 31.5 kDa

Positive Control: Mesothelioma

Cellular Localization: Nuclear and Cytoplasmic

This antibody is excellent for staining of formalin-fixed, paraffin-embedded tissues.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)


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