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Your search for "msr1" returned 78 TaqMan® Gene Expression Assays
macrophage scavenger receptor 1
This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008]
CD204, MRS-A, MSR, MSR-A, MSR1, PHSR1, PHSR2, RGD1564316, SCARA1, SCVR, SR-A, SR-AI, SR-AII, SRA
|Protocol||Protocol: TaqMan® Gene Expression Assays||PDF, 2349.1 KB|
|App Note||Application Note: TaqMan® Gene Expression Assays Endogenous Controls||PDF, Unknown KB|
|QRC||QRC: TaqMan® Gene Expression Assays||PDF, 200.9 KB|
|White Paper||Design Process for Gene Expression Assays||PDF, Unknown KB|
|White Paper||Gene Expression Assay Performance Guarantee||PDF, 481.9 KB|
|White Paper||TaqMan® Assays shipped at ambient temperature retain their quality and stability||PDF, Unknown KB|
|Brochure||Understanding Your Shipment||PDF, 3726.3 KB|
|White Paper||Product Stability Study||PDF, Unknown KB|
|Spreadsheet||Pathogen Assay Information||XLSX, Unknown KB|
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