Your search for "ccdc88a" returned 459 TaqMan® SNP Genotyping Assays
coiled-coil domain containing 88A
This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
A430106J12RIK, AI848406, APE, C130096N06RIK, C330012F17RIK, CCDC88A, D130005J21RIK, GIRDIN, GIV, GRDN, HKRP1, KIAA1212, RGD1306694
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