Thermo Scientific sulfur-containing compounds

Organosulfur compounds are responsible for the unpleasant odors of decaying organic matter. Among the 20 common amino acids, two are organosulfur compounds. Thiols, thioethers, thioesters, thioureas, sulfonamides, and sulfoxides are some of the important classes of sulfur products. Sulfur compounds are involved in many chemical reactions as useful intermediates, including the Herz reaction which is a chemical reaction of an aniline-derivative with disulfur dichloride to give an organosulfur compound, Herz salt, as an intermediate from which the corresponding sodium thiolate is formed.

Thermo Fisher Scientific offers sulfur-containing compounds suitable for a range of laboratory research applications.

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Organic sulfides, alternatively referred to as thioethers, are compounds that contain a C-S-C linkage. They readily form stable sulfonium salts when alkylated. These sulfonium salts can be used to prepare sulfur ylides. Sulfides have wide applicability and are the precursors for sulfoxides and sulfones. Sulfides are extensively used in the synthesis of organic compounds that find applications in the research and development of drugs, property-enhancing additives, rubber oxidants, and agricultural chemicals. They are sometimes used as solvents for extraction.

Disulfides are a class of compounds which contains a sulfur-sulfur linkage. In organic synthesis, disulfides are used to prepare other sulfur containing compounds. Aryl disulfides can be used to activate carboxylic acid as aryl thioesters for the subsequent preparation of substituted amides, as often used in β-lactam antibiotic chemistry. With chlorine under milder conditions, disulfide forms sulfenyl chlorides, while under harder conditions, they form sulfonic acid.

Other Thermo Scientific organosulfur compounds, suitable for a variety of research applications, include sulfonyls, sulfoxides, thioureas, and more.

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