In recent years, the use of LC-MS/MS for pesticide analysis has become increasingly popular due to the amenability of electrospray ionization (ESI) for polar compounds. Traditionally, water samples are extracted in a very time consuming manner, using 1 L of sample that is concentrated 100-1000 times before analysis. This extraction can take several hours or even days of preparation time. Also, the added expense of extraction cartridges leads to more expense per sample for labs. EQuan is a solution that allows for automated online preconcentration of samples without the need for extensive sample preparation or manual intervention.
This application note describes the Multi-residue assay of a group of pesticides in drinking water by EQuan. The method utilizes SRM for Quantification, followed by Data Dependent™ QED MS/MS and library searching for the structural confirmation of these analytes.
