Act now to install this critical update to enhance the security of your Thermo Scientific Xcalibur/Foundation software. This update will take less than two minutes to install and does not change processing capabilities or data associated with your software program.

Installation instructions

Please carefully read the Xcalibur/Foundation Software Release Notes prior to installation to ensure success and to avoid any impact to your data acquisition.

To install the update you need local Windows administrative privileges on the computer being updated. If you require additional assistance, please contact your systems administrator for support.

Once clicked, a .zip file will automatically download to your system. Open the downloaded file to run the .exe file to complete the installation.

If you have any difficulty downloading or installing, please complete the form on this webpage to receive technical assistance.

Do I need the update?

The update is required for all current and past users of Thermo Scientific Xcalibur/Foundation software and must be deployed on all computers that run or have ever run the software programs listed below. Although Xcalibur/Foundation software is frequently used in support of chromatography and mass spectrometry systems, this update is also required for all current and past users, including those who use Xcalibur/Foundation to process data and are not connected to instruments, and those who have run demonstration versions of the software in the past. Even if you have deleted the software from your computer, you must run this update. The security update applies to users of software programs including, but not limited to:

  • Thermo Scientific Xcalibur/Foundation software
  • Thermo Scientific Chromeleon Chromatography Data System (CDS) software
  • Thermo Scientific Compound Discoverer software
  • Thermo Scientific Proteome Discoverer software
  • Thermo Scientific BioPharma Finder software
  • Thermo Scientific FreeStyle software
  • Thermo Scientific TraceFinder software
  • Thermo Scientific LCquan software
  • Thermo Scientific ClinQuan software

Contact us

If you have questions or technical difficulties, please fill out the form below. Thank you for your immediate attention to this update.


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Please provide as much information about the version of software and instrument(s) you are using so that we can connect you with an appropriate technical assistant.

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