Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
H2B histone family, member D; H2B/d; H2BFD; HIST1H2BN; histone 1, H2bn; Histone H2B type 1-N; Histone H2B.d; Histone H2Bd