IL28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Cytokine ZCYTO20; IFN-lambda-2; IFNL2; IL-28A; Interferon lambda-2; interferon, lambda 2; interferon-lambda 2; interleukin 28A (interferon, lambda 2); Interleukin-28A; ZCYTO20
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