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This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA. Two alternatively spliced transcript variants that encode different proteins have been found.
1110027I23Rik; AIBP80; alpha integrin-binding protein 80; AU022044; DNA repair protein REV1; REV1; REV1 homolog; REV1 homolog (S. cerevisiae); REV1- like; REV1, DNA directed polymerase; REV1, polymerase (DNA directed); REV1L; rev1-like terminal deoxycytidyl transferase
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100 µg
100 µL