Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the Krüppel C2H2-type zinc-finger protein family, ZNF498 (zinc finger protein 498), also known as Zinc finger and SCAN domain-containing protein 25 (ZSCAN25), is a 544 amino acid protein. Localized to the nucleus, ZNF498 contains seven C2H2-type zinc fingers and one SCAN box domain. Due to the presence of these domains, ZNF498 is believed to be involved in transcriptional regulation. ZNF498 exists as 4 isoforms produced by alternative splicing.
Zinc finger and SCAN domain-containing protein 25; Zinc finger protein 498