Product References
Synthetic lethality of drug-induced polyploidy and BCL-2 inhibition in lymphoma.
Nature communications
Portelinha A,da Silva Ferreira M,Erazo T,Jiang M,Asgari Z,de Stanchina E,Younes A,Wendel HG
Sat Mar 18 00:00:00 EDT 2023
The mechanism of acentrosomal spindle assembly in human oocytes.
Science (New York, N.Y.)
Wu T,Dong J,Fu J,Kuang Y,Chen B,Gu H,Luo Y,Gu R,Zhang M,Li W,Dong X,Sun X,Sang Q,Wang L
Fri Nov 18 00:00:00 EST 2022
Proteomic Mapping and Targeting of Mitotic Pericentriolar Material in Tumors Bearing Centrosome Amplification.
Cancer research
Xie B,Pu Y,Yang F,Chen W,Yue W,Ma J,Zhang N,Jiang Y,Wu J,Lin Y,Liang X,Wang C,Zou P,Li M
Mon Jul 18 00:00:00 EDT 2022
Expression Analyses of Polo-Like Kinase 4, a Gene Product Responsible for Autosomal Recessive Microcephaly and Seckel Syndrome, during Mouse Brain Development.
Developmental neuroscience
Hamada N,Iwamoto I,Noda M,Nishikawa M,Nagata KI
Tue Feb 14 00:00:00 EST 2023
Expression Analyses of Polo-Like Kinase 4, a Gene Product Responsible for Autosomal Recessive Microcephaly and Seckel Syndrome, during Mouse Brain Development.
Developmental neuroscience
Hamada N,Iwamoto I,Noda M,Nishikawa M,Nagata KI
Tue Feb 14 00:00:00 EST 2023
Expression Analyses of Polo-Like Kinase 4, a Gene Product Responsible for Autosomal Recessive Microcephaly and Seckel Syndrome, during Mouse Brain Development.
Developmental neuroscience
Hamada N,Iwamoto I,Noda M,Nishikawa M,Nagata KI
Tue Feb 14 00:00:00 EST 2023
Effects of the PLK4 inhibitor Centrinone on the biological behaviors of acute myeloid leukemia cell lines.
Frontiers in genetics
Mu XR,Ma MM,Lu ZY,Liu J,Xue YT,Cao J,Zeng LY,Li F,Xu KL,Wu QY
Wed Sep 07 00:00:00 EDT 2022
ENKD1 promotes CP110 removal through competing with CEP97 to initiate ciliogenesis.
EMBO reports
Song T,Yang Y,Zhou P,Ran J,Zhang L,Wu X,Xie W,Zhong T,Liu H,Liu M,Li D,Zhao H,Zhou J
Wed May 04 00:00:00 EDT 2022
Polo-like kinase 4 as a potential predictive biomarker of chemoradioresistance in locally advanced rectal cancer.
Journal of pathology and translational medicine
Oh H,Kim SG,Bae SU,Byun SJ,Kim S,Lee JH,Hwang I,Kwon SY,Lee HW
Sat Jan 01 00:00:00 EST 2022
Defect of IL17 Signaling, but Not Centrinone, Inhibits the Development of Psoriasis and Skin Papilloma in Mouse Models.
Biomedicines
Jin B,Zhang Y,Miller HD,He L,Ge D,Wang AR,You Z
Mon Aug 15 00:00:00 EDT 2022
Defect of IL17 Signaling, but Not Centrinone, Inhibits the Development of Psoriasis and Skin Papilloma in Mouse Models.
Biomedicines
Jin B,Zhang Y,Miller HD,He L,Ge D,Wang AR,You Z
Mon Aug 15 00:00:00 EDT 2022
MicroRNA‑126 suppresses the proliferation and migration of endothelial cells in experimental diabetic retinopathy by targeting polo‑like kinase 4.
International journal of molecular medicine
Zheng Y,Liu Y,Wang L,Xu H,Lu Z,Xuan Y,Meng W,Ye L,Fang D,Zhou Y,Ke K,Liu Y,An M
Fri Jan 01 00:00:00 EST 2021
MicroRNA‑126 suppresses the proliferation and migration of endothelial cells in experimental diabetic retinopathy by targeting polo‑like kinase 4.
International journal of molecular medicine
Zheng Y,Liu Y,Wang L,Xu H,Lu Z,Xuan Y,Meng W,Ye L,Fang D,Zhou Y,Ke K,Liu Y,An M
Fri Jan 01 00:00:00 EST 2021
Down-regulation of Polo-like kinase 4 (PLK4) induces G1 arrest via activation of the p38/p53/p21 signaling pathway in bladder cancer.
FEBS open bio
Yang Z,Sun H,Ma W,Wu K,Peng G,Ou T,Wu S
Wed Sep 01 00:00:00 EDT 2021
Characteristic Analysis of Featured Genes Associated With Stemness Indices in Colorectal Cancer.
Frontiers in molecular biosciences
Lu Y,Zhou X,Liu Z,Wang W,Li F,Fu W
Tue Nov 03 00:00:00 EST 2020
High PLK4 expression promotes tumor progression and induces epithelial‑mesenchymal transition by regulating the Wnt/β‑catenin signaling pathway in colorectal cancer.
International journal of oncology
Liao Z,Zhang H,Fan P,Huang Q,Dong K,Qi Y,Song J,Chen L,Liang H,Chen X,Zhang Z,Zhang B
Fri Feb 01 00:00:00 EST 2019
High PLK4 expression promotes tumor progression and induces epithelial‑mesenchymal transition by regulating the Wnt/β‑catenin signaling pathway in colorectal cancer.
International journal of oncology
Liao Z,Zhang H,Fan P,Huang Q,Dong K,Qi Y,Song J,Chen L,Liang H,Chen X,Zhang Z,Zhang B
Fri Feb 01 00:00:00 EST 2019
POLQ Overexpression Is Associated with an Increased Somatic Mutation Load and PLK4 Overexpression in Lung Adenocarcinoma.
Cancers
Shinmura K,Kato H,Kawanishi Y,Yoshimura K,Tsuchiya K,Takahara Y,Hosokawa S,Kawase A,Funai K,Sugimura H
Fri May 24 00:00:00 EDT 2019
LncRNA SNHG1 contributes to tumorigenesis and mechanism by targeting miR-338-3p to regulate PLK4 in human neuroblastoma.
European review for medical and pharmacological sciences
Zhang N,Liu FL,Ma TS,Zhang ZZJ
Tue Oct 01 00:00:00 EDT 2019
NudC-like protein 2 restrains centriole amplification by stabilizing HERC2.
Cell death & disease
Li M,Xu X,Zhang J,Liu M,Wang W,Gao Y,Sun Q,Zhang J,Lu Y,Wang F,Liu W,Zhou T,Yang Y
Mon Aug 19 00:00:00 EDT 2019
Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo.
Molecular cancer therapeutics
Liu K,Fang L,Sun H,Pan Z,Zhang J,Chen J,Shao X,Wang W,Tan Y,Ding Z,Ao L,Wu C,Liu X,Li H,Wang R,Su W,Li H
Tue May 01 00:00:00 EDT 2018
Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo.
Molecular cancer therapeutics
Liu K,Fang L,Sun H,Pan Z,Zhang J,Chen J,Shao X,Wang W,Tan Y,Ding Z,Ao L,Wu C,Liu X,Li H,Wang R,Su W,Li H
Tue May 01 00:00:00 EDT 2018
Polo-like kinase 4 mediates epithelial-mesenchymal transition in neuroblastoma via PI3K/Akt signaling pathway.
Cell death & disease
Tian X,Zhou D,Chen L,Tian Y,Zhong B,Cao Y,Dong Q,Zhou M,Yan J,Wang Y,Qiu Y,Zhang L,Li Z,Wang H,Wang D,Ying G,Zhao Q
Fri Jan 19 00:00:00 EST 2018
Polo-like kinase 4 mediates epithelial-mesenchymal transition in neuroblastoma via PI3K/Akt signaling pathway.
Cell death & disease
Tian X,Zhou D,Chen L,Tian Y,Zhong B,Cao Y,Dong Q,Zhou M,Yan J,Wang Y,Qiu Y,Zhang L,Li Z,Wang H,Wang D,Ying G,Zhao Q
Fri Jan 19 00:00:00 EST 2018
Polo-like kinase 4 mediates epithelial-mesenchymal transition in neuroblastoma via PI3K/Akt signaling pathway.
Cell death & disease
Tian X,Zhou D,Chen L,Tian Y,Zhong B,Cao Y,Dong Q,Zhou M,Yan J,Wang Y,Qiu Y,Zhang L,Li Z,Wang H,Wang D,Ying G,Zhao Q
Fri Jan 19 00:00:00 EST 2018
Polo-like kinase 4 mediates epithelial-mesenchymal transition in neuroblastoma via PI3K/Akt signaling pathway.
Cell death & disease
Tian X,Zhou D,Chen L,Tian Y,Zhong B,Cao Y,Dong Q,Zhou M,Yan J,Wang Y,Qiu Y,Zhang L,Li Z,Wang H,Wang D,Ying G,Zhao Q
Fri Jan 19 00:00:00 EST 2018
Novel compound heterozygous variants in PLK4 identified in a patient with autosomal recessive microcephaly and chorioretinopathy.
European journal of human genetics : EJHG
Tsutsumi M,Yokoi S,Miya F,Miyata M,Kato M,Okamoto N,Tsunoda T,Yamasaki M,Kanemura Y,Kosaki K,Saitoh S,Kurahashi H
Thu Dec 01 00:00:00 EST 2016
Novel compound heterozygous variants in PLK4 identified in a patient with autosomal recessive microcephaly and chorioretinopathy.
European journal of human genetics : EJHG
Tsutsumi M,Yokoi S,Miya F,Miyata M,Kato M,Okamoto N,Tsunoda T,Yamasaki M,Kanemura Y,Kosaki K,Saitoh S,Kurahashi H
Thu Dec 01 00:00:00 EST 2016
Molecular basis of the STIL coiled coil oligomerization explains its requirement for de-novo formation of centrosomes in mammalian cells.
Scientific reports
David A,Amartely H,Rabinowicz N,Shamir M,Friedler A,Izraeli S
Thu Apr 14 00:00:00 EDT 2016
Molecular basis of the STIL coiled coil oligomerization explains its requirement for de-novo formation of centrosomes in mammalian cells.
Scientific reports
David A,Amartely H,Rabinowicz N,Shamir M,Friedler A,Izraeli S
Thu Apr 14 00:00:00 EDT 2016
S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation.
Molecular and cellular biology
Nakagawa T,Araki T,Nakagawa M,Hirao A,Unno M,Nakayama K
Thu Oct 01 00:00:00 EDT 2015
S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation.
Molecular and cellular biology
Nakagawa T,Araki T,Nakagawa M,Hirao A,Unno M,Nakayama K
Thu Oct 01 00:00:00 EDT 2015
Loss of KLF14 triggers centrosome amplification and tumorigenesis.
Nature communications
Fan G,Sun L,Shan P,Zhang X,Huan J,Zhang X,Li D,Wang T,Wei T,Zhang X,Gu X,Yao L,Xuan Y,Hou Z,Cui Y,Cao L,Li X,Zhang S,Wang C
Tue Oct 06 00:00:00 EDT 2015
Loss of KLF14 triggers centrosome amplification and tumorigenesis.
Nature communications
Fan G,Sun L,Shan P,Zhang X,Huan J,Zhang X,Li D,Wang T,Wei T,Zhang X,Gu X,Yao L,Xuan Y,Hou Z,Cui Y,Cao L,Li X,Zhang S,Wang C
Tue Oct 06 00:00:00 EDT 2015
Loss of KLF14 triggers centrosome amplification and tumorigenesis.
Nature communications
Fan G,Sun L,Shan P,Zhang X,Huan J,Zhang X,Li D,Wang T,Wei T,Zhang X,Gu X,Yao L,Xuan Y,Hou Z,Cui Y,Cao L,Li X,Zhang S,Wang C
Tue Oct 06 00:00:00 EDT 2015
Loss of KLF14 triggers centrosome amplification and tumorigenesis.
Nature communications
Fan G,Sun L,Shan P,Zhang X,Huan J,Zhang X,Li D,Wang T,Wei T,Zhang X,Gu X,Yao L,Xuan Y,Hou Z,Cui Y,Cao L,Li X,Zhang S,Wang C
Tue Oct 06 00:00:00 EDT 2015
Male hypogonadism and germ cell loss caused by a mutation in Polo-like kinase 4.
Endocrinology
Harris RM,Weiss J,Jameson JL
Sat Oct 01 00:00:00 EDT 2011
Male hypogonadism and germ cell loss caused by a mutation in Polo-like kinase 4.
Endocrinology
Harris RM,Weiss J,Jameson JL
Sat Oct 01 00:00:00 EDT 2011