Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody is specific to the C-term of delta chain, CaMKII delta. It can recognize most isoforms the gene encodes, from 50-72 kDa. It can recognize isoforms 2, 3, 4, 9, 11.
Immunogen sequence: MASTTTCTR FTDEYQLFEE LGKGAFSVVR RCMKIPTGQE YAAKIINTKK LSARDHQKLE REARICRLLK HPNIVRLHDS ISEEGFHYLV FDLVTGGELF EDIVAREYYS EADASHCIQQ ILESVNHCHL NGIVHRDLKP ENLLLASKSK GAAVKLADFG LAIEVQGDQQ AWFGFAGTPG YLSPEVLRKD PYGKPVDMWA CGVILYILLV GYPPFWDEDQ HRLYQQIKAG AYDFPSPEWD TVTPEAKDLI NKMLTINPAK RITASEALKH PWIC (1-273 aa encoded by BC032784)
CaMKII delta belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. is a delta chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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