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Immunogen sequence: YIYYNDVYA FNLDTFTWSK LSPSGTGPTP RSGCQMSVTP QGGIVVYGGY SKQRVKKDVD KGTRHSDMFL LKPEDGREDK WVWTRMNPSG VKPTPRSGFS VAMAPNHQTL FFGGVCDEEE EESLSGEFFN DLYFYDATRN RWFEGQLKGP KSEKKKRRRG RKEEPEGGSR PACGGAGTQG PVQLVKEVVA EDGTVVTIKQ VLTAPGSAGQ PRSEDEDSLE EAGSPAPGPC PRSNAMLAVK HGVLYVYGGM FEAGDRQVTL SDLHCLDLHR MEAWKALVEM DPETQEWLEE TDSEEDSEEV EGAEGGVDDE DSGEESGAED (171-489 aa encoded by BC011680)
Kelch proteins (and Kelch-like proteins) are proteins that have repeated kelch domains. Most Kelch proteins also have a BTB (defn) domain. Each kelch domain forms the blade of a propellar structure, with the repeated kelch domains forming a Beta-propellar. The structure of this Beta-propellar is known but the function is not characterised. KLHDC4 contains six Kelch repeats. There are three named isoforms.
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Protein Aliases: Kelch domain-containing protein 4
Gene Aliases: AA408426; AV352552; BC012312; G430025P05Rik; KLHDC4
UniProt ID: (Human) Q8TBB5
Entrez Gene ID: (Human) 54758, (Mouse) 234825
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